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1Academic Journal
المؤلفون: Baasanjav Uranbileg, Junken Aoki, Kuniyuki Kano, Makoto Kurano, Masahiko Sumitani, Nobuko Ito, Yutaka Yatomi
المصدر: Medical Mass Spectrometry. 2022, 6(2):85
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المؤلفون: Mo Wang, C. Chris Yun, Yiran Han, Lei Dong, Peijian He
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1073-1092 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Lipopolysaccharide, RC799-869, RT-PCR, reverse transcriptase polymerase chain reaction, IEC, intestinal epithelial cell, Cell membrane, chemistry.chemical_compound, Transactivation, Mice, 0302 clinical medicine, LPA5, FD-4, fluorescein isothiocyanate-labeled 4 kDa dextran, Lysophosphatidic acid, Intestinal Mucosa, Receptors, Lysophosphatidic Acid, Receptor, Original Research, ATX, autotaxin, IBD, inflammatory bowel disease, Dextran Sulfate, Gastroenterology, Diseases of the digestive system. Gastroenterology, GI, gastrointestinal, Colitis, Cell biology, LPA, medicine.anatomical_structure, TJ, tight junction, shRNA, short hairpin RNA, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, Signal transduction, JAMs, junctional adhesion molecules, Rac1, LPA, lysophosphatidic acid, LPA5, LPA receptor 5, Barrier, PBS, phosphate-buffered saline, RAC1, ROCK, RhoA-associated kinase, Permeability, TER, transepithelial electrical resistance, Cell Line, GEF, guanine nucleotide exchange factor, 03 medical and health sciences, Stat, signal transducers and activators of transcription, DSS, dextran sulfate sodium, medicine, Animals, Humans, IF, immunofluorescence, GPCR, G protein-coupled receptor, Intestinal permeability, Hepatology, Stat3, NHE3, Na+/H+ exchanger 3, medicine.disease, AJ, adherens junction, EGFR, epidermal growth factor receptor, Disease Models, Animal, 030104 developmental biology, chemistry, Caco-2 Cells, Lysophospholipids, SD, standard deviation
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المؤلفون: Nicole D. Bouvy, Marion J.J. Gijbels, Audrey C. H. M. Jongen, Hong Liu, Ron M. A. Heeren, Jianhua Cao, Benjamin Balluff, Jarno Melenhorst
المساهمون: Surgery, RS: NUTRIM - R2 - Liver and digestive health, Imaging Mass Spectrometry (IMS), RS: M4I - Imaging Mass Spectrometry (IMS), Pathologie, Moleculaire Genetica, RS: Carim - B07 The vulnerable plaque: makers and markers, RS: GROW - R2 - Basic and Translational Cancer Biology, MUMC+: MA Heelkunde (9), Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes
المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 35-41 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier BVمصطلحات موضوعية: Pathology, medicine.medical_treatment, Clinical Biochemistry, H&E stain, MULTICENTER, Abdominal wall, Laparotomy, PHOSPHATIDYLCHOLINE, Medicine, PE, Phosphatidylethanolamine, Fascia, skin and connective tissue diseases, GROWTH-FACTORS, Incisional hernia, Spectroscopy, PI, Phosphatidylinositol, Lipids, Medical Laboratory Technology, CerPE, Ceramide phosphorylethanolamine, medicine.anatomical_structure, LPC, Lysophosphatidylcholine, PHOSPHATIDYLETHANOLAMINE METABOLISM, lipids (amino acids, peptides, and proteins), HEALTH, PA, Phosphatidic acid, medicine.medical_specialty, PC, Phosphatidylcholine, AA, Arachidonic acid, BIOLOGY, Wound healing, Abdominal fascia, Microbiology, Special issue on Lipidomics, GM3, Monosialodihexosylganglioside, Mass spectrometry imaging, Medical technology, R855-855.5, Fibroblast, SM, Sphingomyelin, business.industry, CYTOKINES, medicine.disease, MMPE, Monomethyl-phosphatidylethanolamine, CLOSURE, sense organs, CL, Cardiolipin, MEMBRANE, business, LPA, Lysophosphatidic acid
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4
المؤلفون: Chieko Iwao, Yoshihiro Shidoji
المصدر: Biochemistry and Biophysics Reports, Vol 28, Iss, Pp 101176-(2021)
Biochemistry and Biophysics Reportsمصطلحات موضوعية: LPE, lysophosphatidylethanolamine, Cell death, Programmed cell death, ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, LCAT, lecithin cholesterol acyltransferase, QH301-705.5, Short Communication, D-MEM, Dulbecco’s modified Eagle’s medium, Biophysics, ATRA, all-trans retinoic acid, Lysophospholipids, Mevalonic acid, QD415-436, KEGG, Kyoto Encyclopedia of Genes and Genomes, Biochemistry, UPLC, ultra-performance liquid chromatography, chemistry.chemical_compound, VIP, variable importance in the projection, Metabolomics, FBS, fetal bovine serum, Q-Tof/MS, quadrupole time-of-flight type mass spectrometry, SPH, second primary hepatoma, Geranylgeranoic acid, GSDMD, gasdermin D, Biology (General), Receptor, TLR4, toll-like receptor-4, PCA, principal component analysis, Hepatoma, LPC, lysophosphatidylcholine, PLA2, phospholipase A2, OPLS-DA, orthogonal partial least squares-discriminant analysis, Pyroptosis, UPRER, unfolded protein response or endoplasmic reticulum stress response, LPL, lysophospholipid, Lysophosphatidylcholine, chemistry, GGA, geranylgeranoic acid, LPCAT, LPC acyltransferase, LIPC, lipase C, HMDB, Human Metabolome Database, LPA, lysophosphatidic acid, Intracellular
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المؤلفون: James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven
المصدر: Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCPمصطلحات موضوعية: Proteomics, Cnp, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, Nadk2, NAD kinase 2, mitochondrial, Pck2, phosphoenolpyruvate carboxykinase [GTP], mitochondrial, Slc16a1, monocarboxylate transporter 1, PPAR, peroxisome proliferator-activated receptor, Mog, myelin-oligodendrocyte glycoprotein, Nfe2l2, nuclear factor erythroid 2-related factor 2, Mlc1, membrane protein MLC1, Biochemistry, C1qc, complement C1q subcomponent subunit C, Transgenic, Analytical Chemistry, Acadl, Long-chain specific acyl-CoA dehydrogenase, mitochondrial, Myelin, Mice, Gsr, glutathione reductase, mitochondrial, Cryl1, lambda-crystallin homolog, Sqstm1, sequestosome-1, BCA, bicinchoninic acid assay, LC3, microtubule-associated protein 1A/1B-light chain 3, Gliosis, SRM, selected reaction monitoring, Aetiology, Gclm, glutamate--cysteine ligase regulatory subunit, μDIA, micro-data-independent acquisition, Acsl3, long-chain-fatty-acid--CoA ligase 3, Cat, catalase, Acot2, Acyl-coenzyme A thioesterase 2, Glial fibrillary acidic protein, Rps27a, ubiquitin-40S ribosomal protein S27a, Acsl6, long-chain-fatty-acid--CoA ligase 6, Aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, Slc25a18, mitochondrial glutamate carrier 2, Bsn, protein bassoon, Fabp7, fatty acid binding protein, brain, Plp1, myelin proteolipid protein, Gsta3, glutathione S-transferase A3, Prdx6, peroxiredoxin-6, Alexander Disease, Slc6a11, sodium- and chloride-dependent GABA transporter 3, Ccnd2, G1/S-specific cyclin-D2, Stxbp5l, syntaxin-binding protein 5-like, GAPDH, glyceraldehyde 3 phosphate dehydrogenase, Slc6a17, sodium-dependent neutral amino acid transporter SLC6A17, Biochemistry & Molecular Biology, Ilk, integrin-linked protein kinase, Kcnj10, ATP-sensitive inward rectifier potassium channel 10, Ugt8, Gan, gigaxonin, Ttyh1, protein tweety homolog 1, Hsp27, heat shock protein beta-1, TBI, traumatic brain injury, reactive gliosis, Hmgcs2, hydroxymethylglutaryl-CoA synthase, mitochondrial, Idh2, isocitrate dehydrogenase [NADP], mitochondrial, KEGG, Kyoto encyclopedia of genes and genomes, Genetics, Humans, Gpr37l1, prosaposin receptor GPR37L1, Molecular Biology, Txnrd1, thioredoxin reductase 1, cytoplasmic, Slc38a3, sodium-coupled neutral amino acid transporter 3, Animal, DAVID, database for annotation, visualization and integrated discovery, GFAP, glial fibrillary acidic protein, astrocytes, Rack1, receptor of activated protein C kinase 1, Ugt8, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Apoa1, apolipoprotein A-I, medicine.disease, Oligodendrocyte, GABA, gamma aminobutyric acid, Slc27a1, long-chain fatty acid transport protein 1, nervous system, Fabp7, Mutation, Mag, myelin-associated glycoprotein, Gclc, glutamate--cysteine ligase catalytic subunit, Gsto1, glutathione S-transferase omega-1, Ephx1, epoxide hydrolase 1, Gpx1, glutathione peroxidase 1, C1qa, complement C1q subcomponent subunit A, MDD, major depressive disorder, Cd44, Cd44 antigen, Slc4a4, electrogenic sodium bicarbonate cotransporter 1, Neurodegenerative, Dlg4, disks large homolog 4, TIC, total ion current, Gstm1, glutathione S-transferase Mu 1, Alexander disease, 2.1 Biological and endogenous factors, Functional ability, Ndrg2, protein NDRG2, Sfxn5, sideroflexin-5, Ca2, carbonic anhydrase 2, S1pr1, sphingosine 1-phosphate receptor 1, Gpx3, glutathione peroxidase 3, Snap25, synaptosomal-associated protein 25, Sparcl1, SPARC-like protein 1, medicine.diagnostic_test, Prdx1, peroxiredoxin-1, medicine.anatomical_structure, Neurological, Pgd, 6-phosphogluconate dehydrogenase, decarboxylating, Mbp, myelin basic protein, LPA, lysophosphatidic acid, Astrocyte, Gss, glutathione synthetase, Stat3, signal transducer and activator of transcription 3, Biotechnology, Sorbs1, Sorbin and SH3 domain-containing protein 1, RFs, Rosenthal fibers, Pygb, glycogen phosphorylase, brain form, Ctsd, cathepsin D, Ddx3x, ATP-dependent RNA helicase DDX3X, Fasn, fatty acid synthase, Slc1a2, excitatory amino acid transporter 2, PPP, pentose phosphate pathway, Mice, Transgenic, Plpp3, phospholipid phosphatase 3, Biology, C1qb, complement C1q subcomponent subunit B, CNS, central nervous system, Gja1, gap junction alpha-1 protein, PRM-MS, parallel reaction monitoring-mass spectrometry, TFA, trifluoro acetic acid, Vim, vimentin, Rare Diseases, Western blot, Downregulation and upregulation, Acox1, peroxisomal acyl-coenzyme A oxidase 1, Mobp, myelin-associated oligodendrocyte basic protein, medicine, Atp1b2, sodium/potassium-transporting ATPase subunit beta-2, Animals, Cryab, alpha-crystallin B chain, MS2, MS/MS or tandem mass spectrometry, Research, Neurosciences, Molecular biology, Ntrk2, BDNF/NT-3 growth factors receptor, Brain Disorders, AxD, Alexander disease, Disease Models, Animal, Acox3, Peroxisomal acyl-coenzyme A oxidase 3, Disease Models, biology.protein, Ugp2, UTP--glucose-1-phosphate uridylyl transferase, Acot1, Acyl-coenzyme A thioesterase 1
وصف الملف: application/pdf
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المؤلفون: Yasuhiro Takenouchi, Hironobu Ishimaru, Keisuke Kitakaze, Kazuhito Tsuboi, Maho Tsuda, Yasuo Okamoto
المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100141-(2021)مصطلحات موضوعية: LPE, lysophosphatidylethanolamine, enzymology, phospholipids/phosphatidic acid, Organophosphonates, Phosphatidic Acids, QD415-436, Naphthalenes, Biochemistry, GDE, glycerophosphodiesterase, Fluorescence, phospholipids/metabolism, chemistry.chemical_compound, cDNA, complementary DNA, Endocrinology, 3-ccPA, 3-carbacyclic phosphatidic acid, Lysophosphatidic acid, LNCaP, Methods, Humans, Anilides, fluorescent substrate, NP-40, Nonidet P-40, Enzyme Assays, LPC, lysophosphatidylcholine, Chemistry, Phosphoric Diester Hydrolases, HEK 293 cells, Cell migration, Cell Biology, Phosphatidic acid, HEK293T, human embryonic kidney 293T, O/E, overexpressing, BrP-LPA, α-bromomethylene phosphonate analog of LPA, HEK293 Cells, Lysophospholipase, lysophospholipid, kinetics, glycerophosphodiesterase, MCF-7 Cells, ATX, autotoxin, Autotaxin, phospholipids/biosynthesis, Intracellular, phospholipases/D, lysophosphatidic acid, LPA, lysophosphatidic acid, lyso-PLD, lysophospholipase D
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المؤلفون: Feng, Hao, Qiwei, Liu, Fuqiang, Zhang, Jiaxin, Du, Amanda, Dumire, Xuemin, Xu, Mei-Zhen, Cui
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: MASMC, mouse aortic smooth muscle cell, TRPP Cation Channels, MAP Kinase Signaling System, Myocytes, Smooth Muscle, SMC, smooth muscle cell, ERK, extracellular-signal-regulated kinase, Muscle, Smooth, Vascular, LPA2, LPA receptor 2, Mitogen-Activated Protein Kinase 14, Mice, LDL, low-density lipoprotein, MEK, mitogen-activated protein kinase kinase, Animals, Mitogen-Activated Protein Kinase 9, Receptors, Lysophosphatidic Acid, oxLDL, oxidized LDL, Egr1, early growth response protein 1, Aorta, LPA1, LPA receptor 1, vascular biology, p38 MAPK, p38 mitogen-activated protein kinases, smooth muscle cells, Enzyme Activation, PKD, protein kinase D, JNK, Jun N-terminal kinases, TF, tissue factor, gene expression, lipids (amino acids, peptides, and proteins), lipid signaling, biological phenomena, cell phenomena, and immunity, Lysophospholipids, atherosclerosis, signal transduction, LPA, lysophosphatidic acid, MAPK, mitogen-activated protein kinase, Research Article
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المؤلفون: Ilaria Casari, Marcello Manfredi, Marco Falasca, Pat Metharom
المصدر: Progress in Lipid Research
مصطلحات موضوعية: 0106 biological sciences, GM3, monosialodihexosyl ganglioside, medicine.medical_treatment, AA, arachidonic acid, Disease, Review, 01 natural sciences, IFNα, interferon α, Biochemistry, S protein, spike protein, ERGIC, ER-Golgi intermediate compartment, DIC, disseminated intravascular coagulation, PUFAs, poly-unsaturated fatty acids, Coronavirus, LPLs, Lysophospholipids, LysoPC, lysophosphatidylcholine, DVT, deep vein thrombosis, RBD, receptor-binding domain, MERS-CoV, Middle East respiratory syndrome coronavirus, TMPRSS2, type II transmembrane serine host cell protease, Lipidome, RO, replication organelles, DHA, C22:6 docosahexaenoic acid, CTD, C-terminal domain, EPA, C20:5 eicosapentaenoic acid, MVB, multivesicular body, plasmenyl-PC, plasmenyl phosphatidylcholine, MAE, microwave-assisted extraction, TAGs, triacylglycerols, VTE, venous thromboembolism, PAs, phosphatidic acids, PCs, phosphatidylcholines, NPC1, receptor Niemann-Pick C1, DMV, double-membrane vesicles, dyslipidaemia, AUC, area under curve, ACE2, angiotensin-converting enzyme 2, 03 medical and health sciences, Viral life cycle, Humans, NTD, N-terminal domain, PAF, platelet-activating factor, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, cPLA2 α, cytosolic phospholipase A2α, PLA2, phospholipase A2, PtdIns3P, monophosphate phosphatidylinositol 3-phosphate, Lipid Metabolism, SARS-CoV, Severe Acute Respiratory Syndrome, S1P, sphingosine 1-phosphates, 030104 developmental biology, Immunology, LPCs, glycerophosphocholines, SPME, solid-phase microextraction, 0301 basic medicine, UAE, ultrasonic-assisted extraction, Viral pathogenesis, coronavirus, LDs, lipid droplets, PtdIns(3,5)P2, bisphosphate phosphatidylinositol 3,5-bisphosphate, medicine.disease_cause, LC-MS, liquid chromatography, Targeted therapy, Pes, glycerophosphoethanolamines, NET, neutrophil extracellular trap, DPA, C22: 5 docosapentaenoic acid, SREBPs, sterol regulatory element-binding proteins, DAGs, diacylglycerols, NEFA, non-esterified fatty acid, HDL, high density lipoproteins, IDL, intermediate density lipoproteins, EBOV, Ebola virus, COVID-19, coronavirus disease 19, LPA, lysophosphatidic acid, PI3K, phosphoinositide 3-kinase, MALDI, matrix-assisted laser desorption/ionization, MCS, membrane contact site, Biology, LMs, lipid mediators, Virus, ER, endoplasmic reticulum, PtdIns, Phosphoinositides, SMs, sphingomyelins, medicine, QqQ, triple quadrupoles, Pandemics, ISTH, International Society on Thrombosis and Haemostasis, ORF, open-reading frame, SARS-CoV-2, SPE, solid-phase extraction, COVID-19, PSTPIPP2, proline-serine-threonine phosphatase-interacting protein 2, RvE3, resolvin E3, Lipid metabolism, Cell Biology, VLDL, very low-density lipoproteins, TC, total cholesterol, NHC, National Health Commission, 010606 plant biology & botany
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المؤلفون: Hongwei Zhang, Juan Wang, Yunwei Han, Pan Zhou
المصدر: Translational Oncology, Vol 14, Iss 4, Pp 101022-(2021)
Translational Oncologyمصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Blood transfusion, Cancer cells, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, EMT, epithelial to mesenchymal transition, Review, P-EVs, platelet-derived extracellular vesicles, PDGF, platelet-derived growth factor, Metastasis, sITP, secondary immune-mediated thrombocytopenia, 0302 clinical medicine, CCDD, cell combination drug delivery, bFGF, basic fibroblast growth factor, TPO, Thrombopoietin, Platelet, 5-HT, 5-hydroxytryptamine, PMP, platelet microparticles, rhTPO, recombinant human thrombopoietin, CTCs, circulating tumor cells, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, VEGF, vascular endothelial growth factor, TNFα, tumor necrosis factor α, Cancer secondary thrombocytopenia, FAK, focal adhesion kinase, 030220 oncology & carcinogenesis, S1P, sphingosine 1-phosphate, PI3K, phosphoinositide 3-kinase, Platelets, medicine.medical_specialty, IL-1, Interleukin-1, ICH, intracranial hemorrhage, TA-GVHD, transfusion-associated graft versus host disease, lcsh:RC254-282, PD-1, programmed cell death protein 1, 03 medical and health sciences, TCIPA, tumor cell induced platelet aggregation, Internal medicine, medicine, PGE2, prostaglandin E2, GARP, Glycoprotein A repetitions predominant, Platelet activation, IL-6, Interleukin-6, Survival rate, business.industry, PD-L1, programmed death-1 ligand, IL-3, Interleukin-3, HSCs, hematopoietic stem cells, Cancer, CLEC-2, C-type lectin-like receptor-2, pITP, primary immune-mediated thrombocytopenia, medicine.disease, TGF-b, transforming growth factor b, CIT, chemotherapy-induced thrombocytopenia, 030104 developmental biology, Platelet transfusion, Cancer cell, TF, tissue factor, Cox-2, cyclooxygenase 2, MMPs, matrix metalloproteinases, Lpa, lysophosphatidic acid, ITP, immune thrombocytopenia, business, MAPK, mitogen-activated protein kinase
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المؤلفون: David A. Ford, Daniel P. Pike, Kaushalya Amunugama
المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100090-(2021)
Journal of Lipid Researchمصطلحات موضوعية: 0301 basic medicine, SIRS, systemic inflammatory response syndrome, TXB2, thromboxane B2, ARDS, LPCAT, lysophosphatidylcholine acyltransferase, HOCl, hypochlorous acid, MPO, myeloperoxidase, AA, arachidonic acid, 030204 cardiovascular system & hematology, Bioinformatics, Biochemistry, Pathogenesis, TPPU, N-[1-(1-oxopropyl)-4-piperidinyl]-N′-[4-(trifluoromethoxy)phenyl]-urea, chemistry.chemical_compound, PC, phosphatidylcholine, 0302 clinical medicine, Endocrinology, AEA, N-arachidonoylethanolamine, prognostics, lipid metabolism, DHET, dihydroxyeicosatrienoic acid, LOX, lipoxygenase, 2-ClSA, 2-chlorostearic acid, ATX, autotaxin, cys-LTs, cysteinyl leukotrienes, Rv, resolvin, TG, triglycerides, CLP, cecal ligation puncture, Lipids, SPMs, specialized pro-resolving mediators, 2-ClFALD, 2-chlorofatty aldehyde, LPS, lipopolysaccharide, RvE1-RvE3, E series resolvins, sPLA2, secretory phospholipase A2, medicine.symptom, Resolvin, LPA, lysophosphatidic acid, bioactive lipids, CEPT, cholesteryl ester transfer, rHDL, recombinant HDL, LTB4, leukotriene B4, RvT1-RvT4, T series resolvins, Inflammation, Cer, ceramide, CS, cecal slurry, QD415-436, Biology, fatty acids, TLR, Toll-like receptors, Sepsis, 03 medical and health sciences, 2-ClFA, 2-chlorofatty acid, medicine, energy imbalance, Humans, cPLA2, cytosolic PLA2, PAF, platelet-activating factor, ARDS, acute respiratory distress syndrome, RvD1-RvD6, D series resolvins, DPA, docosapentaenoic acid, S1P, sphingosine-1-phosphate, 2-ClPA, 2- chloropalmitic acid, LPC, lysophosphatidylcholine, Organ dysfunction, PLA2, phospholipase A2, EET, epoxy-eicosatrienoic acid, cholesterol, biomarkers, resolution, Lipid metabolism, Thematic Review Series, Cell Biology, Sphk, sphingosine kinase, SOFA, sequential organ failure assessment, medicine.disease, sEH, soluble epoxide hydrolase, Systemic inflammatory response syndrome, COX, cyclooxygenase, TC, total cholesterol, 030104 developmental biology, chemistry, LTA, lipotechoic acid, inflammation, 10S,17S- diHDHA, 10(S),17(S) dihydroxy docosahexaenoic acid, sepsis pathogenesis, CYP450, cytochrome P450, PCSK9, proprotein convertase subtilisin/kexin type 9, 2-AG, 2-Arachidonoylglycerol
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المؤلفون: Michal Holčapek, Kim Ekroos, Nils Hoffmann, Xianlin Han, Gerhard Liebisch, Erin S. Baker, Markus R. Wenk, Robert Ahrends, Harald Köfeler
المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100138-(2021)
Journal of Lipid Researchمصطلحات موضوعية: RT, retention time, HILIC, hydrophilic interaction liquid chromatography, HRMS, high-resolution MS, spektrometrie iontové mobility, Computer science, Biochemistry, Mass Spectrometry, Thematic Review Series: Lipidomics: General, ICR, ion cyclotron resonance, LCF, lipid class-specific fragment, PC, phosphatidylcholine, Endocrinology, UHPSFC, ultrahigh-performance supercritical fluid chromatography, ion mobility spectrometry, UHPLC, ultrahigh-performance liquid chromatography, Species identification, IS, internal standard, SRM, selected reaction monitoring, QTOF, quadrupole TOF, LSI, Lipidomics Standards Initiative, TG, triglyceride, Lipids, metabolomics, SPE, solid phase extraction, chromatography, chromatografie, LPA, lysophosphatidic acid, lipid identification, Research groups, TIMS, trapped ion mobility spectrometry, QqQ, triple quadrupole, Best practice, TWIMS, traveling wave ion mobility spectrometry, QD415-436, fosfolipidy, sfingolipidy, lipidomika, Lipidomics, metabolomika, Humans, Good practice, DTIMS, drift tube ion mobility spectrometry, phospholipids, S1P, sphingosine-1-phosphate, Protocol (science), sphingolipids, identifikace lipidů, IMS, ion mobility spectrometry, Thematic Review Series, Cell Biology, FAIMS, field asymmetric waveform ion mobility spectrometry, MS, Data science, ILS, International Lipidomics Society, LC-MS, Workflow, Data quality, lipidomics, RP, reverse-phase
وصف الملف: application/pdf; p. 100138
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المؤلفون: Lisa G. Lippert, Abhinandan Jain, Michael Ritt, Ning Ma, Nagarajan Vaidehi, Sivaraj Sivaramakrishnan
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Protein Kinase C-alpha, Allosteric regulation, DMSO, dimethyl sulfoxide, Molecular Dynamics Simulation, G-loop, Gly-rich loop, Biochemistry, Cell Line, Diglycerides, 03 medical and health sciences, FBS, fetal bovine serum, Allosteric Regulation, Protein Domains, PKCα, protein kinase Cα, REU, Rosetta energy units, SMKI, small molecule kinase inhibitor, Animals, Humans, Binding site, Kinase activity, PKC, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, Protein kinase C, Diacylglycerol kinase, protein translocation, 030102 biochemistry & molecular biology, Chemistry, PKCα, Cell Membrane, Cell Biology, PS, pseudosubstrate, Small molecule, inhibitor, Molecular Docking Simulation, Protein Transport, 030104 developmental biology, kinases, Protein kinase domain, Biophysics, DAG, diacylglycerol, LPA, lysophosphatidic acid, Research Article
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المؤلفون: Nozomu Kono, Makoto Kurano, Junken Aoki, Kuniyuki Kano, Yutaka Yatomi, Hirotaka Matsumoto
المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100029-(2021)
Journal of Lipid Researchمصطلحات موضوعية: 0301 basic medicine, autotaxin, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, PRP, platelet-rich plasma, PC, phosphatidylcholine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Phosphatidylcholine, Lysophosphatidic acid, Methods, plasma, Platelet-poor plasma, Whole blood, ATX, autotaxin, LPC, lysophosphatidylcholine, PPP, platelet-poor plasma, LPL, lysophospholipid, Cell Biology, Metabolism, CTAD, citrate-theophylline-adenosine-dipyridamole, lysoPLD, lysophospholipase D, LC-MS, 030104 developmental biology, Lysophosphatidylcholine, chemistry, Platelet-rich plasma, biomarker, lipids (amino acids, peptides, and proteins), clinical specimen, Lysophospholipids, Autotaxin, biological phenomena, cell phenomena, and immunity, metabolism, LPA, lysophosphatidic acid, lysophosphatidic acid
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المؤلفون: Haruka Yamada, Fumio Sakane, Fumi Hoshino, Qiang Lu
المصدر: Biochemistry and Biophysics Reports, Vol 22, Iss, Pp-(2020)
Biochemistry and Biophysics Reportsمصطلحات موضوعية: 0301 basic medicine, PABD, phosphatidic acid-binding domain, α-Syn-N, N-terminal region of α-Syn, Neurite, animal diseases, Lysine, Diacylglycerol kinase, Biophysics, α-Syn, α-synuclein, Myr, myristoylated, Biochemistry, LPAAT, LPA acyltransferase, lcsh:Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, PC, phosphatidylcholine, 0302 clinical medicine, Phosphatidic acid, Phospholipase D, Lipid sensor, heterocyclic compounds, lcsh:QD415-436, PA, phosphatidic acid, Growth cone, PLD, phospholipase D, lcsh:QH301-705.5, Phagosome, α-Synuclein, DMEM, Dulbecco's modified Eagle's medium, FIPI, 5-fluoro-2-indolyl deschlorohalopemide, Cell biology, nervous system diseases, Glutamine, F-actin, filamentous actin, 030104 developmental biology, DGK, diacylglycerol kinase, chemistry, nervous system, lcsh:Biology (General), 030220 oncology & carcinogenesis, LPA, lysophosphatidic acid, Research Article
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15Academic Journal
المساهمون: Smith, Richard
المصدر: Journal of Proteome Research, 7(10):4215-24; 7; 10
وصف الملف: Medium: X
URL الوصول: http://www.osti.gov/scitech/biblio/974991
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المؤلفون: Xue-Mei Peng, Zhuan Zhou, Jie Li, Shan Gao, Lu-Yuan Li, Zhi-Song Zhang, Tai-Ran Bai, Dao-Lei Dou, Li-Song Zhang
المصدر: EBioMedicine
مصطلحات موضوعية: 0301 basic medicine, Research paper, GRASP55, Golgi reassembly-stacking protein, Membrane trafficking, shRNA, Short hairpin RNA, Ligands, Breast cancer, Cell Movement, Epidermal growth factor receptor, RNA, Small Interfering, IP, Immunoprecipitation, Progression, biology, RHBDF1, Human rhomboid family-1 gene, Chemistry, H&E, Haematoxylin and Eosin staining, Clathrin-Coated Vesicles, General Medicine, GPCR, G protein-coupled receptors, TGFα, Transforming growth factor-α, Cell biology, ErbB Receptors, Protein Transport, AP-1 transcription factor, S1P, Sphingosine-1-phosphate, RHBDF1, Disease Progression, Female, Protein Binding, Clathrin-coated vesicle, EGFR, Auxilins, CCVs, Clathrin-coated vesicles, Breast Neoplasms, ADAM17 Protein, Models, Biological, Clathrin, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cell Line, Tumor, HSC70, Heat shock cognate protein-70, EGFR, Epidermal growth factor receptor, medicine, ELISA, Enzyme-linked immuno sorbent assay, Humans, Gene silencing, Secretion, ADAM17, ADAM metallopeptidase domain 17, TGFα, Cell Proliferation, G protein-coupled receptor, IF, Immunofluorescence, HSC70 Heat-Shock Proteins, Membrane Proteins, Cancer, RT-qPCR, Reverse transcription quantitative PCR, Transforming Growth Factor alpha, medicine.disease, 030104 developmental biology, biology.protein, AP1, Clathrin-associated adaptor protein complex-1, LPA, Lysophosphatidic acid, Transforming growth factor
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المؤلفون: Hyung Wook Nam, Md. Shenuarin Bhuiyan, Kevin J. McCarthy, Sumitra Miriyala, Paari Dominic, Andrew J. Morris, Manikandan Panchatcharam, Anthony W Orr, Diana Escalante-Alcalde, Christopher G. Kevil, Mini Chandra
المصدر: Redox Biology, Vol 14, Iss, Pp 261-271 (2018)
Redox Biologyمصطلحات موضوعية: Male, 0301 basic medicine, Bioenergetics, Clinical Biochemistry, Plpp3, Phospholipid phosphatase 3, Mitochondrion, Biochemistry, Mitochondria, Heart, Mice, chemistry.chemical_compound, Lysophosphatidic acid, Natriuretic peptide, PA, phosphatidic acid, lcsh:QH301-705.5, Mice, Knockout, lcsh:R5-920, medicine.anatomical_structure, Knockout mouse, Intercalated disc, lcsh:Medicine (General), LPA, lysophosphatidic acid, Signal Transduction, Research Paper, medicine.medical_specialty, MAP Kinase Signaling System, medicine.drug_class, Phosphatidate Phosphatase, Biology, 03 medical and health sciences, Oxygen Consumption, Internal medicine, medicine, Animals, Sarcomere organization, Heart Failure, Myocardium, Organic Chemistry, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, lcsh:Biology (General), Heart failure, Lipid phosphate phosphatase, Lysophospholipids, Energy Metabolism, Gene Deletion
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المؤلفون: Irving García-Jiménez, Alejandro Castillo Kauil, Jorge Eduardo del-Río-Robles, Guadalupe Reyes-Cruz, Rodolfo Daniel Cervantes-Villagrana, Yarely Mabell Beltrán-Navarro, José Vázquez-Prado, Jonathan García-Román
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: actin cytoskeleton, Lung Neoplasms, RHOA, cell migration, NSCLC, non–small cell lung carcinoma, Rho guanine nucleotide exchange factor, Biochemistry, Mice, RhoGEF, Rho guanine nucleotide exchange factor, Cell Movement, GTP-Binding Protein gamma Subunits, LPAR, lysophosphatidic acid receptor, Tumor Microenvironment, Neoplasm Metastasis, Receptors, Lysophosphatidic Acid, EGFP, enhanced GFP, DMEM, Dulbecco's modified Eagle's medium, GTP-Binding Protein beta Subunits, PTX, pertussis toxin, Disease Progression, Guanine nucleotide exchange factor, Signal transduction, signal transduction, LPA, lysophosphatidic acid, Research Article, ARHGEF17, heterotrimeric G protein, ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, ERK, extracellular-regulated kinase, Biology, Gbetagamma, FBS, fetal bovine serum, GST, glutathione-S-transferase, medicine, Animals, Humans, Lung cancer, Molecular Biology, Tumor microenvironment, HEK 293T, human embryonic kidney 293T cell line, PAE, porcine aortic endothelial, Cancer, RhoA, Cell Biology, medicine.disease, Actin cytoskeleton, Cancer cell, Cancer research, biology.protein, GPCR, G protein–coupled receptor, lysophosphatidic acid, Rho Guanine Nucleotide Exchange Factors
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المؤلفون: Hyeon-Joong Kim, Hyewhon Rhim, Ik Hyun Cho, Hyoung-Chun Kim, Seung Yeol Nah, Manho Kim, Seok Won Jung, Seog Young Kim
المصدر: Journal of Ginseng Research
Journal of Ginseng Research, Vol 42, Iss 4, Pp 401-411 (2018)مصطلحات موضوعية: 0301 basic medicine, Ginsenoside, PPARγ, peroxisome proliferator-activated receptor-γ, NGF, nerve growth factor, NMDA, n-methyl-d-aspartic acid, Review Article, Pharmacology, Gintonin, GLP151, ginseng major latex-like protein 151, Biochemistry, Genetics and Molecular Biology (miscellaneous), Neuroprotection, sAPPα, soluble amyloid precursor protein α, 03 medical and health sciences, Ginseng, chemistry.chemical_compound, 0302 clinical medicine, ROS, reactive oxygen species, APP, amyloid precursor protein, lcsh:Botany, AChE, acetylcholinesterase, medicine, Adjuvant, Aβ, amyloid β-protein, business.industry, Neurotoxicity, Panax ginseng, PI3K, phosphoinositide-3 kinase, Alzheimer's disease, medicine.disease, Acetylcholinesterase, Choline acetyltransferase, lcsh:QK1-989, 030104 developmental biology, Complementary and alternative medicine, chemistry, EGF, Epidermal growth factor, BDNF, brain-derived neurotrophic factor, Cholinergic, AD, Alzheimer's disease, business, 030217 neurology & neurosurgery, Acetylcholine, Biotechnology, medicine.drug, LPA, Lysophosphatidic acid
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المؤلفون: Daisuke Takahashi, Chiaki Murakami, Fumi Hoshino, Fumio Sakane, Suguru Komenoi, Yuji Suzuki, Sayaka Kado, Maho Asami, Sohei Chiba
المصدر: Biochemistry and Biophysics Reports, Vol 19, Iss, Pp-(2019)
Biochemistry and Biophysics Reportsمصطلحات موضوعية: 0301 basic medicine, WT, wild type, LC-MS, liquid chromatography-mass spectrometry, Diacylglycerol kinase, Gh, growth hormone, Biochemistry, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Gene expression, Phosphatidic acid, DG, diacylglycerol, lcsh:QD415-436, PA, phosphatidic acid, Receptor, lcsh:QH301-705.5, BPD, bipolar disorder, Glp1r, glucagon-like peptide 1 receptor, Chemistry, Cell biology, DGK, diacylglycerol kinase, 030220 oncology & carcinogenesis, Knockout mouse, Signal transduction, Lysophosphatidic acid, LPA, lysophosphatidic acid, Research Article, Prl, prolactin, Bipolar disorder, Il1b, interleukin 1β, Biophysics, GO:BP, Gene Ontology: Biological Process, MEK, mitogen-activated protein kinase/ERK kinase, KEGG, Kyoto Encyclopedia of Genes and Genomes, PI, phosphatidylinositol, SERT, serotonin transporter, Biological pathway, lcsh:Biochemistry, 03 medical and health sciences, PUFA, polyunsaturated fatty acid, Fpr2, N-formyl peptide receptor 2, DAVID, Database for AnnotationVisualization and Integrated Discovery, GWAS, genome-wide association study, Gene, Growth hormone, KO, knockout, Microarray analysis techniques, Prolactin, 030104 developmental biology, lcsh:Biology (General)