المؤلفون: Muotri, Alysson R

المصدر: Genetics and Molecular Biology. 46(1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Stem Cell Research, Human Genome, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research - Nonembryonic - Human, Mental Health, Neurosciences, Generic health relevance, L1 retrotransposition, neural progenitor cells, translocations, brain mosaicism, Genetics & Heredity, Plant Biology & Botany

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9bb9p94q
https://escholarship.org/content/qt9bb9p94q/qt9bb9p94q.pdf

المؤلفون: Alysson R. Muotri

المصدر: Genetics and Molecular Biology, Vol 46, Iss 1 (2023)

مصطلحات موضوعية: L1 retrotransposition, neural progenitor cells, translocations, brain mosaicism, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000100701&lng=en&tlng=en; http://www.scielo.br/pdf/gmb/v46n1/1415-4757-GMB-46-1-e20220268.pdf; https://doaj.org/toc/1678-4685

URL الوصول: https://doaj.org/article/8b8c9d3f5f8342b39eb5750d35afdf52

المؤلفون: McKerrow, Wilson, Wang, Xuya, Mendez-Dorantes, Carlos, Mita, Paolo, Cao, Song, Grivainis, Mark, Ding, Li, LaCava, John, Burns, Kathleen H., Boeke, Jef D., Fenyo, David

المصدر: McKerrow , W , Wang , X , Mendez-Dorantes , C , Mita , P , Cao , S , Grivainis , M , Ding , L , LaCava , J , Burns , K H , Boeke , J D & Fenyo , D 2022 , ' LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 119 , no. 8 , e2115999119 . https://doi.org/10.1073/pnas.2115999119

مصطلحات موضوعية: retrotransposon, LINE-1, cancer, DNA damage response, copy number alteration, INTEGRATED PROTEOGENOMIC CHARACTERIZATION, L1 RETROTRANSPOSITION, DNA-REPAIR, REVERSE TRANSCRIPTION, ATM, PHOSPHORYLATION, GENE, SMC1, AUTOPHOSPHORYLATION, PROTEINS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/53227d52-bf4e-4ff9-9d05-eafbec03b01c
https://research.rug.nl/en/publications/53227d52-bf4e-4ff9-9d05-eafbec03b01c
https://doi.org/10.1073/pnas.2115999119
https://pure.rug.nl/ws/files/217831018/pnas.2115999119.pdf

المؤلفون: GO Bodea, JM Botto, ME Ferreiro, FJ Sanchez-Luque, J de los Rios Barreda, J Rasmussen, MA Rahman, LR Fenlon, N Jansz, C Gubert, P Gerdes, LG Bodea, P Ajjikuttira, DJ Da Costa Guevara, L Cumner, CC Bell, P Kozulin, V Billon, S Morell, MJHC Kempen, Chloe Love, K Saha, LM Palmer, AD Ewing, DJ Jhaveri, SR Richardson, AJ Hannan, GJ Faulkner

مصطلحات موضوعية: Biomedical and clinical sciences, Neurosciences, Psychology, Biological psychology, Cognitive and computational psychology, CELLS, DIVERSITY, DNA, ELEMENT, EXPRESSION, FAMILY, HUMAN L1 RETROTRANSPOSITION, Life Sciences & Biomedicine, MECHANISM, METHYLATION, Neurosciences & Neurology, Science & Technology, TRANSCRIPTION

Relation: http://hdl.handle.net/10779/DRO/DU:26043967.v2

الاتاحة: http://hdl.handle.net/10779/DRO/DU:26043967.v2
https://figshare.com/articles/journal_contribution/LINE-1_retrotransposons_contribute_to_mouse_PV_interneuron_development/26043967

المؤلفون: Cajuso, Tatiana, Sulo, Paivi, Tanskanen, Tomas, Katainen, Riku, Taira, Aurora, Hanninen, Ulrika A., Kondelin, Johanna, Forsstrom, Linda, Valimaki, Niko, Aavikko, Mervi, Kaasinen, Eevi, Ristimaki, Ari, Koskensalo, Selja, Lepisto, Anna, Renkonen-Sinisalo, Laura, Seppala, Toni, Kuopio, Teijo, Bohm, Jan, Mecklin, Jukka-Pekka, Kilpivaara, Outi, Pitkanen, Esa, Palin, Kimmo, Aaltonen, Lauri A.

المساهمون: Genome-Scale Biology (GSB) Research Program, Research Programs Unit, Department of Medical and Clinical Genetics, Medicum, Department of Pathology, HUSLAB, Helsinki University Hospital Area, HUS Abdominal Center, Department of Surgery, Clinicum, II kirurgian klinikka, Lauri Antti Aaltonen / Principal Investigator, Machine learning in biomedicine

مصطلحات موضوعية: SOMATIC L1 RETROTRANSPOSITION, ISLAND METHYLATOR PHENOTYPE, WHOLE-GENOME, MICROSATELLITE INSTABILITY, SVA ELEMENTS, CPG, HYPOMETHYLATION, GENE, Cancers, Biomedicine

وصف الملف: application/pdf

Relation: The authors thank Alison Ollikainen, Iina Vuoristo, Inga-Lill Aberg, Sini Marttinen, Marjo Rajalaakso, Sirpa Soisalo, Jiri Hamberg, and Heikki Metsola for technical assistance and Alison Ollikainen also for proofreading the manuscript. This work was supported by grants from the Academy of Finland (Finnish Center of Excellence Program 2012-2017, 250345 and 2018-2025, 312041), The Finnish Cancer Society, The European Research Council (268648), The Sigrid Juselius Foundation; Jane and Aatos Erkko Foundation, the Nordic Information for Action eScience Center (NIASC) and Nordic Center of Excellence financed by NordForsk (Project number 62721). We also thank SYSCOL (an EU FP7 Collaborative Project, 258236) for sequencing the RNA samples. The following foundations are acknowledged for personal funding: Ida Montinin Saatio foundation, Cancer Society of Finland, Juhani Ahon Foundation for Medical Research and The Maud Kuistila Memorial Foundation. The authors wish to acknowledge CSC-IT Center for Science, Finland, for computational resources.; Cajuso , T , Sulo , P , Tanskanen , T , Katainen , R , Taira , A , Hanninen , U A , Kondelin , J , Forsstrom , L , Valimaki , N , Aavikko , M , Kaasinen , E , Ristimaki , A , Koskensalo , S , Lepisto , A , Renkonen-Sinisalo , L , Seppala , T , Kuopio , T , Bohm , J , Mecklin , J-P , Kilpivaara , O , Pitkanen , E , Palin , K & Aaltonen , L A 2019 , ' Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival ' , Nature Communications , vol. 10 , 4022 . https://doi.org/10.1038/s41467-019-11770-0; ORCID: /0000-0002-5866-4059/work/62632075; ORCID: /0000-0002-4940-3498/work/62633365; ORCID: /0000-0002-1333-8049/work/91815961; ORCID: /0000-0001-6839-4286/work/101502618; ORCID: /0000-0002-1179-8500/work/156152272; ORCID: /0000-0001-8467-2100/work/156157837; http://hdl.handle.net/10138/305752; 6eabac58-950c-4e4d-8cec-44fe540a8e99; 000484596900002

الاتاحة: http://hdl.handle.net/10138/305752

المؤلفون: Ardeljan, Daniel, Wang, Xuya, Oghbaie, Mehrnoosh, Taylor, Martin S., Husband, David, Deshpande, Vikram, Steranka, Jared P., Gorbounov, Mikhail, Yang, Wan Rou, Sie, Brandon, Larman, H. Benjamin, Jiang, Hua, Molloy, Kelly R., Altukhov, Ilya, Li, Zhi, McKerrow, Wilson, Fenyo, David, Burns, Kathleen H., LaCava, John

المصدر: Ardeljan , D , Wang , X , Oghbaie , M , Taylor , M S , Husband , D , Deshpande , V , Steranka , J P , Gorbounov , M , Yang , W R , Sie , B , Larman , H B , Jiang , H , Molloy , K R , Altukhov , I , Li , Z , McKerrow , W , Fenyo , D , Burns , K H & LaCava , J 2019 , ' LINE-1 ORF2p expression is nearly imperceptible in human cancers ' , Mobile dna , vol. ....

مصطلحات موضوعية: HIGH-FREQUENCY RETROTRANSPOSITION, SOMATIC L1 RETROTRANSPOSITION, TRIMERIC STRUCTURE, MASS-SPECTROMETRY, PROTEIN, INSERTIONS, ENDONUCLEASE, IDENTIFICATION, MUTAGENESIS, MUTATIONS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/f085b5b9-bc0b-4495-81a7-f264d35c0303
https://research.rug.nl/en/publications/f085b5b9-bc0b-4495-81a7-f264d35c0303
https://doi.org/10.1186/s13100-019-0191-2
https://pure.rug.nl/ws/files/113182791/LINE_1_ORF2p_expression_is_nearly_imperceptible_in_human_cancers.pdf

المؤلفون: Álvarez-Lindo, Noemí, Baleriola, Jimena, Ríos, Vivian de los, Suárez, Teresa, De la Rosa, Enrique J.

المساهمون: Ministerio de Economía y Competitividad (España), Álvarez-Lindo, Noemí, Baleriola, Jimena, de los Ríos, Vivian, De la Rosa, Enrique J.

مصطلحات موضوعية: Recombination-activating gene-1, Strand break repair, L1 retrotransposition, Neuronal migration, DNA-damage, Light-chain, Mice, Mutations, Choice, Expression

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-41059-R; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2016-75681-R; Publisher's version; https://doi.org/10.1038/s41598-019-54873-w; Sí; Scientific Reports 9(1)18486 (2019); http://hdl.handle.net/10261/197241; http://dx.doi.org/10.13039/501100003329

الاتاحة: http://hdl.handle.net/10261/197241
https://doi.org/10.1038/s41598-019-54873-w
https://doi.org/10.13039/501100003329

المؤلفون: MacLennan, Marie, Garcia-Canadas, Marta, Reichmann, Judith, Khazina, Elena, Wagner, Gabriele, Playfoot, Christopher J., Salvador-Palomeque, Carmen, Mann, Abigail R., Peressini, Paula, Sanchez, Laura, Dobie, Karen, Read, David, Hung, Chao-Chun, Eskeland, Ragnhild, Meehan, Richard R., Weichenrieder, Oliver, Luis Garcia-Perez, Jose, Adams, Ian R.

المساهمون: MacLennan, Marie Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Reichmann, Judith Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Playfoot, Christopher J. Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Mann, Abigail R. Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Dobie, Karen Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Read, David Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Hung, Chao-Chun Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Meehan, Richard R. Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Luis Garcia-Perez, Jose Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Adams, Ian R. Univ Edinburgh, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland, Garcia-Canadas, Marta Pfizer Univ Granada Junta Andalucia, PTS Granada, Ctr Genom & Invest Oncol GENYO, Granada, Spain, Salvador-Palomeque, Carmen Pfizer Univ Granada Junta Andalucia, PTS Granada, Ctr Genom & Invest Oncol GENYO, Granada, Spain, Peressini, Paula Pfizer Univ Granada Junta Andalucia, PTS Granada, Ctr Genom & Invest Oncol GENYO, Granada, Spain, Sanchez, Laura Pfizer Univ Granada Junta Andalucia, PTS Granada, Ctr Genom & Invest Oncol GENYO, Granada, Spain, Luis Garcia-Perez, Jose Pfizer Univ Granada Junta Andalucia, PTS Granada, Ctr Genom & Invest Oncol GENYO, Granada, Spain, Khazina, Elena Max Planck Inst Dev Biol, Dept Biochem, Tubingen, Germany, Wagner, Gabriele Max Planck Inst Dev Biol, Dept Biochem, Tubingen, Germany, Weichenrieder, Oliver Max Planck Inst Dev Biol, Dept Biochem, Tubingen, Germany, Eskeland, Ragnhild Univ Oslo, Dept Biosci, Oslo, Norway, Eskeland, Ragnhild Oslo Univ Hosp, Dept Immunol, Norwegian Ctr Stem Cell Res, Oslo, Norway, Medical Research Council, Howard Hughes Medical Institute, Wellcome, Max-Planck-Gesellschaft, Kreftforeningen, Universitetet i Oslo, Ministerio de Economia y Competitividad, H2020 European Research Council ERC, Seventh Framework Programme, Consejeria de Economia, Innovacion, Ciencia y Empleo, Junta de Andalucia, MRC

مصطلحات موضوعية: High-frequency retrotransposition, Human l1 retrotransposition, Piwi-interacting rnas, End rule pathway, Ubiquitin ligase, Dna methylation, Orf1 protein, Transposable elements, Chaperone activity, Binding protein

Relation: http://hdl.handle.net/10668/19396; https://doi.org/10.7554/elife.26152; 407617500001

الاتاحة: http://hdl.handle.net/10668/19396
https://doi.org/10.7554/eLife.26152

المؤلفون: Kassiotis, G, Stoye, JP

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, endogenous retroviruses, cancer, immunogenicity, GERM-CELL TUMORS, GROWTH IN-VIVO, K HERV-K, HUMAN TISSUES, L1 RETROTRANSPOSITION, TESTIS ANTIGEN, T-LYMPHOCYTES, IDENTIFICATION, EXPRESSION, MELANOMA, Genetic Pleiotropy, Humans, Neoplasms, 06 Biological Sciences, 11 Medical And Health Sciences, Evolutionary Biology

Relation: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES; http://hdl.handle.net/10044/1/61550; https://dx.doi.org/10.1098/rstb.2016.0277

الاتاحة: http://hdl.handle.net/10044/1/61550
https://doi.org/10.1098/rstb.2016.0277

المؤلفون: Maag, Jesper L. V., Panja, Deb, Sporild, Ida, Patil, Sudarshan, Kaczorowski, Dominik C., Bramham, Clive R., Dinger, Marcel E., Wibrand, Karin

المساهمون: Theoretical Physics

مصطلحات موضوعية: long noncoding RNA (IncRNA), LTP (long term potentiation), retrotransposons, repeat elements, rat brain, time-series data, synaptic plasticity (LTP/LTD), GYRUS IN-VIVO, TERM POTENTIATION, GENE-EXPRESSION, DENTATE GYRUS, L1 RETROTRANSPOSITION, CELL-DIFFERENTIATION, NERVOUS-SYSTEM, MESSENGER-RNA, HUMAN BRAIN, TRANSPOSABLE ELEMENTS

وصف الملف: image/pdf

Relation: https://dspace.library.uu.nl/handle/1874/323863

الاتاحة: https://dspace.library.uu.nl/handle/1874/323863

المؤلفون: Cowley, Michael, Oakey, Rebecca J.

المصدر: Cowley , M & Oakey , R J 2013 , ' Transposable Elements Re-Wire and Fine-Tune the Transcriptome ' , PL o S Genetics , vol. 9 , no. 1 , e1003234 , pp. N/A . https://doi.org/10.1371/journal.pgen.1003234

مصطلحات موضوعية: EMBRYONIC STEM-CELLS, HUMAN GENOME, ENDOGENOUS RETROVIRUSES, L1 RETROTRANSPOSITION, DNA METHYLATION, LINE-1 RETROTRANSPOSITION, EPIGENETIC INHERITANCE, GENE-EXPRESSION, GERM-CELLS, ALU EXONS

Relation: https://kclpure.kcl.ac.uk/portal/en/publications/40e76cc1-b29b-4817-9a12-fd895b138f98

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/40e76cc1-b29b-4817-9a12-fd895b138f98
https://doi.org/10.1371/journal.pgen.1003234

المؤلفون: Shaoline Sheppard, Didier Trono, Sagane Dind, Alexandre Coudray, Julien Duc, Christopher Playfoot, Evarist Planet

المصدر: Genome Res

مصطلحات موضوعية: Transposable element, Adult, Primates, Endogenous retrovirus, RNA-Seq, Computational biology, Biology, Genome, endogenous retroviruses, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, expression, evolution, Gene expression, Genetics, medicine, Animals, Humans, Gene Regulatory Networks, Gene, Genetics (clinical), 030304 developmental biology, Zinc finger, 0303 health sciences, Genome, Human, Research, Brain, Promoter, Human brain, zinc-finger genes, l1 retrotransposition, medicine.anatomical_structure, rna-seq, genome-wide association, DNA Transposable Elements, cells, identification, Human genome, Female, 030217 neurology & neurosurgery, metaanalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5f478a7f4c4fc9671666fa9e473cf0
https://pubmed.ncbi.nlm.nih.gov/34400477

المؤلفون: Rodriguez-Martin, B., Alvarez, E.G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y.S., Temes, J., Garcia-Souto, D., Detering, H., Li, Y., Rodriguez-Castro, J., Dueso-Barroso, A., Bruzos, A.L., Dentro, S.C., Blanco, M.G., Contino, G., Ardeljan, D., Tojo, M., Roberts, N.D., Zumalave, S., Edwards, P.A., Weischenfeldt, J., Puiggròs, M., Chong, Z., Chen, K., Lee, E.A., Wala, J.A., Raine, K., Butler, A., Waszak, S.M., Navarro, F.C.P., Schumacher, S.E., Monlong, J., Maura, F., Bolli, N., Bourque, G., Gerstein, M., Park, P.J., Wedge, D.C., Beroukhim, R., Torrents, D., Korbel, J.O., Martincorena, I., Fitzgerald, R.C., Van Loo, P., Kazazian, H.H., Burns, K.H., Akdemir, K.C., Boutros, P.C., Bowtell, D.D.L., Brors, B., Campbell, P.J., Chan, K., Cortés-Ciriano, I., Dunford, A.J., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J.L., Frenkel-Morgenstern, M., Garsed, D.W., Gordenin, D.A., Haan, D., Haber, J.E., Hess, J.M., Hutter, B., Imielinski, M., Jones, D.T.W., Kazanov, M.D., Klimczak, L.J., Koh, Y., Kumar, K., Lee, J.J.-K., Lynch, A.G., Macintyre, G., Markowetz, F., Martinez-Fundichely, A., Meyerson, M., Miyano, S., Nakagawa, H., Ossowski, S., Pearson, J.V., Rippe, K., Roberts, S.A., Scully, R., Shackleton, M., Sidiropoulos, N., Sieverling, L., Stewart, C., Tubio, J.M.C., Villasante, I., Waddell, N., Yang, L., Yao, X., Yoon, S.-S., Zhang, C.-Z.

المساهمون: University of St Andrews. School of Medicine, University of St Andrews. Statistics, University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis, University of St Andrews. Cellular Medicine Division

المصدر: Nature Genetics
Nature Genetics, 52, 306-319
Rodriguez-Martin, B, Alvarez, E G, Baez-Ortega, A, Zamora, J, Supek, F, Demeulemeester, J, Santamarina, M, Ju, Y S, Temes, J, Garcia-Souto, D, Detering, H, Li, Y, Rodriguez-Castro, J, Dueso-Barroso, A, Bruzos, A L, Dentro, S C, Blanco, M G, Contino, G, Ardeljan, D, Tojo, M, Roberts, N D, Zumalave, S, Edwards, P A, Weischenfeldt, J, Puiggròs, M, Chong, Z, Chen, K, Lee, E A, Wala, J A, Raine, K, Butler, A, Waszak, S M, Navarro, F C P, Schumacher, S E, Monlong, J, Maura, F, Bolli, N, Bourque, G, Gerstein, M, Park, P J, Wedge, D C, Beroukhim, R, Torrents, D, Korbel, J O, Martincorena, I, Fitzgerald, R C, Van Loo, P, Kazazian, H H, Burns, K H, Akdemir, K C, Alvarez, E G, Baez-Ortega, A, Beroukhim, R, Boutros, P C, Bowtell, D D L, Brors, B, Burns, K H, Campbell, P J, Chan, K, Chen, K, Cortés-Ciriano, I, Dueso-Barroso, A, Dunford, A J, Edwards, P A, Estivill, X, Etemadmoghadam, D, Feuerbach, L, Fink, J L, Frenkel-Morgenstern, M, Garsed, D W, Gerstein, M, Gordenin, D A, Haan, D, Haber, J E, Hess, J M, Hutter, B, Imielinski, M, Jones, D T W, Ju, Y S, Kazanov, M D, Klimczak, L J, Koh, Y, Korbel, J O, Kumar, K, Lee, E A, Lee, JJ-K, Li, Y, Lynch, A G, Macintyre, G, Markowetz, F, Martincorena, I, Martinez-Fundichely, A, Meyerson, M, Miyano, S, Nakagawa, H, Navarro, F C P, Ossowski, S, Park, P J, Pearson, J V, Puiggròs, M, Rippe, K, Roberts, N D, Roberts, S A, Rodriguez-Martin, B, Schumacher, S E, Scully, R, Shackleton, M, Sidiropoulos, N, Sieverling, L, Stewart, C, Torrents, D, Tubio, J M C, Villasante, I, Waddell, N, Wala, J A, Weischenfeldt, J, Yang, L, Yao, X, Yoon, S-S, Zamora, J, Zhang, C-Z, Campbell, P J & Tubio, J M C 2020, ' Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition ', Nature Genetics, vol. 52, no. 3, pp. 306-319 . https://doi.org/10.1038/s41588-019-0562-0
Rodriguez-Martin, B, Alvarez, E G, Baez-Ortega, A, Zamora, J, Supek, F, Demeulemeester, J, Santamarina, M, Ju, Y S, Temes, J, Garcia-Souto, D, Detering, H, Li, Y, Rodriguez-Castro, J, Dueso-Barroso, A, Bruzos, A L, Dentro, S C, Blanco, M G, Contino, G, Ardeljan, D, Tojo, M, Roberts, N D, Zumalave, S, Edwards, P A W, Weischenfeldt, J, Puiggròs, M, Chong, Z, Chen, K, Lee, E A, Wala, J A, Raine, K, Butler, A, Waszak, S M, Navarro, F C P, Schumacher, S E, Monlong, J, Maura, F, Bolli, N, Bourque, G, Gerstein, M, Park, P J, Wedge, D C, Beroukhim, R, Torrents, D, Korbel, J O, Martincorena, I, Fitzgerald, R C, Van Loo, P, Kazazian, H H, Sidiropoulos, N, Weischenfeldt, J, PCAWG Structural Variation Working Group & PCAWG Consortium 2020, ' Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition ', Nature Genetics, vol. 52, no. 3, pp. 306-319 . https://doi.org/10.1038/s41588-019-0562-0
Nature Genetics, 52, 3, pp. 306-319

مصطلحات موضوعية: Somatic cell, Carcinogenesis, QH301 Biology, Retrotransposon, medicine.disease_cause, Genoma humà, Genome, 0302 clinical medicine, Neoplasms, ELEMENTS, Carcinogènesi, Cancer, Genetics, Gene Rearrangement, Genetics & Heredity, 0303 health sciences, Women's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17], Manchester Cancer Research Centre, 3rd-DAS, Genomics, Neoplasms/genetics, SOMATIC RETROTRANSPOSITION, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], 3. Good health, READ ALIGNMENT, 030220 oncology & carcinogenesis, Retroelements/genetics, Life Sciences & Biomedicine, Retroelements, INSTABILITY, L1 RETROTRANSPOSITION, QH426 Genetics, Biology, Article, Structural variation, RC0254, 03 medical and health sciences, QH301, SDG 3 - Good Health and Well-being, medicine, Humans, QH426, 030304 developmental biology, Tumors, Science & Technology, LANDSCAPE, RC0254 Neoplasms. Tumors. Oncology (including Cancer), Genome, Human, ResearchInstitutes_Networks_Beacons/mcrc, DELETION, Gene rearrangement, DNA, Gene Rearrangement/genetics, Long interspersed nuclear element, Reordenament genètic, Long Interspersed Nucleotide Elements, Long Interspersed Nucleotide Elements/genetics, Genome, Human/genetics, Carcinogenesis/genetics, Genètica

وصف الملف: Print-Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1bee2c01b8278d49bbe8813c2939cf
https://lirias.kuleuven.be/handle/123456789/651107

المؤلفون: Teresa Suárez, Noemí Álvarez-Lindo, Enrique J. de la Rosa, Vivian de los Ríos, Jimena Baleriola

المساهمون: Ministerio de Economía y Competitividad (España), Álvarez-Lindo, Noemí, Baleriola, Jimena, de los Ríos, Vivian, De la Rosa, Enrique J., Álvarez-Lindo, Noemí [0000-0003-3355-5494], Baleriola, Jimena [0000-0001-9628-4631], de los Ríos, Vivian [0000-0001-5582-6879], De la Rosa, Enrique J. [0000-0001-9984-9706]

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

مصطلحات موضوعية: Retinal Ganglion Cells, Strand break repair, Programmed cell death, DNA damage, lcsh:Medicine, Developmental neurogenesis, Expression, Biology, Axonogenesis, Neuronal migration, Article, Retina, Histones, chemistry.chemical_compound, Mice, Choice, medicine, Animals, DNA Breaks, Double-Stranded, Phosphorylation, lcsh:Science, Mice, Knockout, Multidisciplinary, Recombination-activating gene-1, Cell Death, DNA-damage, lcsh:R, Neurogenesis, Retinal, L1 retrotransposition, Axons, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Retinal ganglion cell, chemistry, Neuronal development, lcsh:Q, Neural development, Mutations, Light-chain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf427d4735d939458153e9d3f09e04c
http://hdl.handle.net/10261/197241

المؤلفون: John LaCava, Zhi Li, Mikhail Gorbounov, H. Benjamin Larman, Wan Rou Yang, Brandon M. Sie, Wilson McKerrow, Mehrnoosh Oghbaie, Hua Jiang, Jared P. Steranka, Kelly R. Molloy, Xuya Wang, David Husband, Daniel Ardeljan, Vikram Deshpande, David Fenyö, Martin S. Taylor, Ilya Altukhov, Kathleen H. Burns

المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE)

المصدر: Mobile DNA
Mobile dna, 11(1):1. BMC
Mobile DNA, Vol 11, Iss 1, Pp 1-19 (2019)

مصطلحات موضوعية: lcsh:QH426-470, Immunoprecipitation, medicine.drug_class, Somatic cell, PROTEIN, Retrotransposon, Biology, Monoclonal antibody, Epitope, 03 medical and health sciences, 0302 clinical medicine, Western blot, Transcription (biology), medicine, TRIMERIC STRUCTURE, Molecular Biology, Gene, 030304 developmental biology, SOMATIC L1 RETROTRANSPOSITION, 0303 health sciences, MUTAGENESIS, IDENTIFICATION, medicine.diagnostic_test, MUTATIONS, Research, INSERTIONS, HIGH-FREQUENCY RETROTRANSPOSITION, MASS-SPECTROMETRY, Molecular biology, Reverse transcriptase, ENDONUCLEASE, 3. Good health, lcsh:Genetics, 030220 oncology & carcinogenesis, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479331235ac7b8944bd99fe954560fa3
http://europepmc.org/articles/PMC6937734

المؤلفون: Banuelos-Sanchez, Guillermo, Sanchez, Laura, Benitez-Guijarro, Maria, Sanchez-Carnerero, Valentin, Salvador-Palomeque, Carmen, Tristan-Ramos, Pablo, Benkaddour-Boumzaouad, Meriem, Morell, Santiago, Garcia-Puche, Jose L., Heras, Sara R., Franco-Montalban, Francisco, Tamayo, Juan A., Garcia-Perez, Jose L.

مصطلحات موضوعية: High-Frequency Retrotransposition, L1 Retrotransposition, Transposable Elements, Modified Nucleosides, Indicator Gene, Stem-Cells, Subfamily, Identification, Transposition, Derivatives

Relation: CS2016-6; Not set; FPU15/03294; IECS-55007420; ERC-STG-2012-309433; SAF2017-89745-R

الاتاحة: https://espace.library.uq.edu.au/view/UQ:0d3b93a

المؤلفون: Riku Katainen, Lauri A. Aaltonen, Ari Ristimäki, Ulrika A. Hänninen, Esa Pitkänen, Aurora Taira, Linda M. Forsström, Tomas Tanskanen, Selja Koskensalo, Niko Välimäki, Laura Renkonen-Sinisalo, Johanna Kondelin, Eevi Kaasinen, Outi Kilpivaara, Teijo Kuopio, Anna Lepistö, Jukka-Pekka Mecklin, Jan Böhm, Tatiana Cajuso, Mervi Aavikko, Päivi Sulo, Kimmo Palin, Toni T. Seppälä

المساهمون: Genome-Scale Biology (GSB) Research Program, Research Programs Unit, Department of Medical and Clinical Genetics, Medicum, Department of Pathology, HUSLAB, Helsinki University Hospital Area, HUS Abdominal Center, Department of Surgery, Clinicum, II kirurgian klinikka, Lauri Antti Aaltonen / Principal Investigator, Machine learning in biomedicine

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Genome instability, MICROSATELLITE INSTABILITY, HYPOMETHYLATION, Carcinogenesis, Colorectal cancer, genetic processes, transposonit, General Physics and Astronomy, Retrotransposon, 02 engineering and technology, Kaplan-Meier Estimate, Genome, 0302 clinical medicine, Cancer genomics, lcsh:Science, Genetics, 0303 health sciences, Gastrointestinal tract, Multidisciplinary, ISLAND METHYLATOR PHENOTYPE, Gastroenterology, food and beverages, genomiikka, Middle Aged, 021001 nanoscience & nanotechnology, 3. Good health, Gene Expression Regulation, Neoplastic, CpG site, syöpägeenit, 030220 oncology & carcinogenesis, DNA methylation, Allelic Imbalance, WHOLE-GENOME, Female, SVA ELEMENTS, 0210 nano-technology, Colorectal Neoplasms, Science, 3122 Cancers, information science, Genomics, suolistosyövät, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Genomic Instability, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Aged, 030304 developmental biology, SOMATIC L1 RETROTRANSPOSITION, CpG Island Methylator Phenotype, Gene Expression Profiling, fungi, Microsatellite instability, General Chemistry, DNA Methylation, medicine.disease, GENE, Mutagenesis, Insertional, 030104 developmental biology, Long Interspersed Nucleotide Elements, CPG, health occupations, Cancer research, lcsh:Q, CpG Islands, 3111 Biomedicine, Caco-2 Cells

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8998dfee8806250d53911716f8a6b7b
https://doi.org/10.1101/443580

المؤلفون: Jose L. Garcia-Perez, Margherita Musella, Valentina Peona, Luca Pagani, Alejandro Rubio-Roldan, Stefania Sarno, Etienne Guichard, Lucia Abitante, Guidantonio Malagoli Tagliazucchi, Cristian Taccioli, Alessio Boattini, Davide Pettener, Evelyn Jagoda, Donata Luiselli, Marco Ricci

المساهمون: Guichard, Etienne, Peona, Valentina, Malagoli Tagliazucchi, Guidantonio, Abitante, Lucia, Jagoda, Evelyn, Musella, Margherita, Ricci, Marco, Rubio-Roldán, Alejandro, Sarno, Stefania, Luiselli, Donata, Pettener, Davide, Taccioli, Cristian, Pagani, Luca, Garcia-Perez, Jose Lui, Boattini, Alessio

المصدر: Mobile DNA
Guichard, E, Peona, V, Tagliazucchi, G M, Abitante, L, Jagoda, E, Musella, M, Ricci, M, Rubio-Roldan, A, Sarno, S, Luiselli, D, Pettener, D, Taccioli, C, Pagani, L, Luis Garcia-Perez, J & Boattini, A 2018, ' Impact of non-LTR retrotransposons in the differentiation and evolution of anatomically modern humans ', Mobile DNA, vol. 9, 28 . https://doi.org/10.1186/s13100-018-0133-4
Mobile DNA, Vol 9, Iss 1, Pp 1-19 (2018)

مصطلحات موضوعية: 0301 basic medicine, Genome evolution, Chimpanzee, Ancient genomes, Lineage (genetic), lcsh:QH426-470, PROMOTER, L1 RETROTRANSPOSITION, CARCINOMA-CELLS, Retrotransposon, Biology, Non-LTR retrotranspososon, SEQUENCE, Genome, 03 medical and health sciences, 0302 clinical medicine, Generation of variability, Genetics, Non-LTR retrotranspososons, Functional analyse, Genetik, Chimpanzees, Molecular Biology, Gene, Human evolution, 030304 developmental biology, GENOME EVOLUTION, 0303 health sciences, Research, Functional analyses, HUMAN BRAIN, Phenotype, Ancient genome, SOMATIC RETROTRANSPOSITION, lcsh:Genetics, 030104 developmental biology, Evolutionary biology, TRANSPOSABLE ELEMENTS, Neuron maturation, Human genome, EMBRYONIC STEM-CELLS, 030217 neurology & neurosurgery, REGULATORY NETWORKS

وصف الملف: application/pdf; ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0cb8168d71d64f758e54d7ecfd5991
https://doi.org/10.1101/207241

المؤلفون: Satoshi Tateishi, Yasuo Ariumi, Hiroyuki Fukuda, Priscilla Turelli, Koudai Kawano, Misao Kuroki, Rokeya Siddiqui, Mariko Yasuda-Inoue

المصدر: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, DNA repair, DNA damage, Ubiquitin-Protein Ligases, mammalian-cells, lcsh:Medicine, Retrotransposon, Biology, embryonic stem-cells, Insert (molecular biology), Article, defective postreplication repair, 03 medical and health sciences, Protein Domains, DNA Repair Protein, Humans, long interspersed element-1, gene delivery, RNA, Small Interfering, lcsh:Science, orf1 protein, Multidisciplinary, complex-formation, lentiviral vector, lcsh:R, HCT116 Cells, l1 retrotransposition, Cell biology, Ubiquitin ligase, DNA-Binding Proteins, genomic DNA, 030104 developmental biology, HEK293 Cells, Long Interspersed Nucleotide Elements, alu retrotransposition, biology.protein, lcsh:Q, Human genome, RNA Interference, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63f77e543a05f51641dabc896693841
https://pubmed.ncbi.nlm.nih.gov/30367120

المؤلفون: Doyle, Glenn A., Crist, Richard C., Karatas, Emre T., Hammond, Matthew J., Ewing, Adam D., Ferraro, Thomas N., Hahn, Chang-Gyu, Berrettini, Wade H.

مصطلحات موضوعية: Dorsolateral Prefrontal Cortex, Genome-Wide Association, Sturge-Weber Syndrome, L1 Retrotransposition, Somatic Mutation, Bipolar Disorder, Disease, Activation, Neurons, Gene, 2738 Psychiatry and Mental health, 3004 Pharmacology

Relation: orcid:0000-0002-4544-994X; 1R21MH101065; 1R01MH109260-01A1; MH096891; DE150101117; Not set; K01-036751; P50MH096891; R21MH101065; R01MH109260

الاتاحة: https://espace.library.uq.edu.au/view/UQ:697678