المؤلفون: Douglas J. Pettibone, Sookhee Ha, Mark Wheatley, Stuart R. Hawtin

المصدر: FEBS Letters. 579:349-356

مصطلحات موضوعية: Models, Molecular, Receptors, Vasopressin, Pyridines, Stereochemistry, Molecular Sequence Data, Glycine, Biophysics, Ligands, Binding, Competitive, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, GPCR, Piperidines, Structural Biology, Oxazines, Genetics, medicine, Humans, Point Mutation, Amino Acid Sequence, Receptor, Oxytocin receptor, Molecular Biology, Ligand binding, G protein-coupled receptor, Alanine, L-371,257, Non-peptide antagonist, Inositol trisphosphate, Cell Biology, Benzoxazines, Transmembrane domain, Amino Acid Substitution, chemistry, Oxytocin, Receptors, Oxytocin, L-368,899, Antidiuretic Hormone Receptor Antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6300c548032e8fa8e18d3ba194b88bdc
https://doi.org/10.1016/j.febslet.2004.10.108

المؤلفون: C. J. Woyden, Roger M. Freidinger, Mark G. Bock, Duane R. Reiss, Joseph M. Pawluczyk, Michelle S. Kuo, Amy G. Quigley, Douglas J. Pettibone, Maribeth T. Guidotti, E V Lis, D. S. Perlow, Peter D. Williams

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:3081-3086

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Ether, Oxytocin, Biochemistry, Chemical synthesis, Oxytocin Antagonist, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Oxazines, Drug Discovery, medicine, Animals, Humans, Molecular Biology, L-371,257, Chemistry, Aryl, Organic Chemistry, Antagonist, Benzoxazines, Rats, Alkoxy group, Molecular Medicine, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765c00dce9dedfe799c42f855a73f496
https://doi.org/10.1016/s0960-894x(98)00568-x

المؤلفون: Douglas J. Pettibone, Peter D. Williams, C. J. Woyden, Roger M. Freidinger, Erb Jm, E V Lis, Duane R. Reiss, Bradley V. Clineschmidt, D. F. Veber, Maribeth T. Guidotti, Joseph M. Pawluczyk

المصدر: ChemInform. 27

مصطلحات موضوعية: chemistry.chemical_compound, L-371,257, Chemistry, Stereochemistry, General Medicine, Non peptide, Oxytocin Antagonist, Bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8bacdd31854d5d30d21f04d2807f88e9
https://doi.org/10.1002/chin.199611203

المؤلفون: A L A L Et Et, Michelle S. Kuo and

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_compound, L-371,257, Oxytocin, chemistry, Stereochemistry, medicine, Ether, General Medicine, medicine.drug, Bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::84f52ad1d4ae998c7988b636d36e8dce
https://doi.org/10.1002/chin.199911149

المؤلفون: Peter D. Williams, et al. et al.

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_compound, L-371,257, Oxytocin, chemistry, medicine, Potency, General Medicine, Pharmacology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b740a34eb46c9f509032463d16de8470
https://doi.org/10.1002/chin.199935177

المؤلفون: B. V. Clineschmidt, Erb Jm, Joseph M. Pawluczyk, Peter D. Williams, E V Lis, Duane R. Reiss, Maribeth T. Guidotti, R. M. Freidinger, D. F. Veber, Douglas J. Pettibone

المصدر: Journal of Medicinal Chemistry. 38:4634-4636

مصطلحات موضوعية: Receptors, Vasopressin, Stereochemistry, Biological Availability, Oxytocin, Non peptide, Oxytocin Antagonist, Uterine Contraction, chemistry.chemical_compound, Obstetric Labor, Premature, Piperidines, Pregnancy, Oral administration, Oxazines, Drug Discovery, medicine, Animals, Humans, L-371,257, Molecular Structure, Bicyclic molecule, Antagonist, Benzoxazines, Rats, Bioavailability, Kinetics, chemistry, Receptors, Oxytocin, Molecular Medicine, Female, Antidiuretic Hormone Receptor Antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffbbb9bfa9df330300e716122c8bdcd
https://doi.org/10.1021/jm00023a002

المؤلفون: Michelle R. Levy, K.J. Stauffer, Roger M. Freidinger, E V Lis, Mark G. Bock, Stuart R. Michelson, Douglas J. Pettibone, D. S. Perlow, Christopher A. Salvatore, Marlene A. Jacobson, B. E. Evans, Joseph M. Pawluczyk, Amy G. Quigley, C. J. Woyden, Maribeth T. Guidotti, Peter D. Williams, Michelle S. Kuo, Steven N. Gallicchio, Duane R. Reiss

المصدر: Bioorganicmedicinal chemistry letters. 9(9)

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Oxytocin, Biochemistry, Oxytocin Antagonist, Cell Line, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Piperidines, In vivo, Drug Discovery, Oxazines, medicine, Potency, Structure–activity relationship, Animals, Humans, Molecular Biology, L-371,257, Chemistry, Organic Chemistry, Antagonist, In vitro, Benzoxazines, Rats, Kinetics, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5060b712acd7d054079f1d505f8a7310
https://pubmed.ncbi.nlm.nih.gov/10340620