المؤلفون: Daniel C Farley, Laura McCloskey, Barbara A Thorne, Semih U Tareen, Christopher J Nicolai, David J Campbell, Richard Bannister, Hannah J Stewart, Laura JE Pearson, Bentley J Moyer, Scott H Robbins, Leah Zielinski, Tae Kim, Pippa A Radcliffe, Kyriacos A Mitrophanous, Wayne R Gombotz, James E Miskin, Brenna Kelley-Clarke

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116300298; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/7f7c5943dd9b4748b580d44545f0e674

المؤلفون: Marisa Zallocchi, Katie Binley, Yatish Lad, Scott Ellis, Peter Widdowson, Sharifah Iqball, Vicky Scripps, Michelle Kelleher, Julie Loader, James Miskin, You-Wei Peng, Wei-Min Wang, Linda Cheung, Duane Delimont, Kyriacos A Mitrophanous, Dominic Cosgrove

المصدر: PLoS ONE, Vol 9, Iss 4, p e94272 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3976400?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/15299d8f6d1046bd8a87be0928d96b1d

المؤلفون: Scott Ellis, Liang Fong-Wong, Sharifah Iqball, Vinay Thoree, Kyriacos A Mitrophanous, Katie Binley

المصدر: Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)

مصطلحات موضوعية: gene therapy, integration-defective, lentiviral vectors, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253116301196; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/4750e5f4e14146d5b05c0ccf43bf2cb4

المؤلفون: Sharifah Iqball, Daniel K. Beck, Gayathri Devarajan, Cheen P. Khoo, Deirdre M. O’Connor, Scott Ellis, Efrain Guzman, Kyriacos A. Mitrophanous, Yatish Lad

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 350-366 (2023)

مصطلحات موضوعية: neovascular AMD, gene therapy, lentiviral vectors, EIAV, HIV-1, aflibercept, Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123001031; https://doaj.org/toc/2329-0501; https://doaj.org/article/bf9e54c2315e4b6d9e5ed33512f892a1

الاتاحة: https://doi.org/10.1016/j.omtm.2023.07.001
https://doaj.org/article/bf9e54c2315e4b6d9e5ed33512f892a1

المؤلفون: Katie Binley, Peter Widdowson, Julie Loader, Michelle Kelleher, Sharifah Iqball, Georgina Ferrige, Jackie De Belin, Marie Carlucci, Diana Angell-Manning, Felicity Hurst, Scott Ellis, James Miskin, Alcides Fernandes, Paul Wong, Rando Allikmets, Christopher Bergstrom, Thomas Aaberg, Jiong Yan, Jian Kong, Peter Gouras, Annick Prefontaine, Mark Vezina, Martin Bussieres, Stuart Naylor, Kyriacos A Mitrophanous

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://iovs.arvojournals.org/data/Journals/IOVS/933468/i1552-5783-54-6-4061.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1087.2376; http://iovs.arvojournals.org/data/Journals/IOVS/933468/i1552-5783-54-6-4061.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1087.2376
http://iovs.arvojournals.org/data/Journals/IOVS/933468/i1552-5783-54-6-4061.pdf

المؤلفون: Roger A. Barker, Gaëtane Gouello, Kyriacos A. Mitrophanous, Nicola J. Tuckwell, Helene Lepetit, G. Scott Ralph, Philippe Domenech, Katy Howard, Sarah L Mason, Philip C. Buttery, Stéphane Palfi, Philippe Hantraye, Jean Marc Gurruchaga

المساهمون: Mason, Sarah [0000-0001-6715-4109], Barker, Roger [0000-0001-8843-7730], Apollo - University of Cambridge Repository

المصدر: Human Gene Therapy Clinical Development. 29:148-155

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Parkinson's disease, Drug-Related Side Effects and Adverse Reactions, Genetic enhancement, Genetic Vectors, Stimulation, Disease, ProSavin, Bioinformatics, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Dopamine, Humans, Medicine, Child, Genetics (clinical), Aged, business.industry, lentiviral vector, Lentivirus, Parkinson Disease, Genetic Therapy, Middle Aged, medicine.disease, gene therapy, Treatment Outcome, 030104 developmental biology, Dopamine receptor, Child, Preschool, Female, dopamine, business, 030217 neurology & neurosurgery, Follow-Up Studies, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3973b40bdc74fe3f79e03bc367fab3bf
https://doi.org/10.1089/humc.2018.081

المؤلفون: Julie Loader, Michelle Kelleher, Kyriacos A. Mitrophanous, Vicky Kennedy, Laura McCloskey, Maria Parker, Naghmeh Fouladi, Scott Ellis, Katie Binley, J. Timothy Stout

المصدر: Human Gene Therapy. 29:687-698

مصطلحات موضوعية: Graft Rejection, 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Genetic enhancement, Genetic Vectors, Cell- and Tissue-Based Therapy, Cell Count, Corneal Transplantation, Neovascularization, 03 medical and health sciences, Corneal Opacity, 0302 clinical medicine, Risk Factors, Cornea, Ophthalmology, Genetics, Animals, Humans, Medicine, Corneal Neovascularization, Tissue Distribution, Angiostatins, Molecular Biology, Intraocular Pressure, Corneal transplantation, Angiostatin, business.industry, Endothelial Cells, Corneal Transplant, eye diseases, Culture Media, Endostatins, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, 030221 ophthalmology & optometry, Molecular Medicine, Female, Rabbits, sense organs, Endostatin, medicine.symptom, Genetic Engineering, business, Keratoplasty, Penetrating, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0153c0134825fbd57e766a152d1ccbb
https://doi.org/10.1089/hum.2017.184

المؤلفون: A Rev-independent Human, Codon-optimized Hiv- Gag-pol Gene, Ekaterini Kotsopoulou, V. Narry Kim, Alan J. Kingsman, Susan M. Kingsman, Kyriacos A. Mitrophanous

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/74/10/4839.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.1852; http://jvi.asm.org/content/74/10/4839.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.1852
http://jvi.asm.org/content/74/10/4839.full.pdf

المؤلفون: Kyriacos A. Mitrophanous, Gareth R.I. Barker, G. Scott Ralph, Liang-Fong Wong, Paul J Banks, Hannah Scott, Zafar I. Bashir, James B. Uney, E. Clea Warburton

المصدر: Barker, G, Banks, P, Scott, H, Wong, L-F, Bashir, Z, Uney, J, Warburton, C, Banks, P J & Scott Ralph, G 2017, ' Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections ', Nature Neuroscience, vol. 20, no. 2, pp. 242–250 . https://doi.org/10.1038/nn.4472

مصطلحات موضوعية: Male, 0301 basic medicine, Memory, Episodic, Prefrontal Cortex, Hippocampus, Hippocampal formation, Spatial memory, 03 medical and health sciences, 0302 clinical medicine, Neural Pathways, Explicit memory, Animals, Semantic memory, Prefrontal cortex, Episodic memory, Spatial Memory, Neurons, Long-term memory, musculoskeletal, neural, and ocular physiology, General Neuroscience, Rats, 030104 developmental biology, nervous system, Nerve Net, Psychology, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f905a7fed82eacfe644476f3341aa1
https://doi.org/10.1038/nn.4472

المؤلفون: Tahreem A. Mir, Peter A. Campochiaro, Elliott H. Sohn, Andreas K. Lauer, Michelle Kelleher, Stuart Naylor, Kyriacos A. Mitrophanous, Scott Ellis, Matthew C. Anderton, Richard Harrop

المصدر: Human Gene Therapy. 28:99-111

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Maximum Tolerated Dose, genetic structures, Genetic Vectors, Viral vector, Cohort Studies, Neovascularization, Equine infectious anemia, Macular Degeneration, 03 medical and health sciences, Internal medicine, Genetics, medicine, Humans, Adverse effect, Angiostatins, Molecular Biology, Macular hole, Research Articles, Aged, Aged, 80 and over, Angiostatin, biology, business.industry, Lentivirus, Genetic Therapy, Macular degeneration, medicine.disease, biology.organism_classification, eye diseases, Endostatins, Surgery, 030104 developmental biology, Molecular Medicine, Female, Injections, Intraocular, medicine.symptom, Endostatin, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc54e87a178f42aab503ded5fd3a38b4
https://doi.org/10.1089/hum.2016.117

المؤلفون: Jeanne Gourlay, Caroline Jan, G. Scott Ralph, Katie Binley, Nadja Van Camp, Hannah J Stewart, Yatish Lad, Julie Loader, Stéphane Palfi, Michelle Kelleher, Romina Aron Badin, Camille Robert, Philippe Hantraye, Koichi Hosomi, Pauline Gipchtein, Audrey Fayard, Kyriacos A. Mitrophanous

المصدر: Molecular Therapy. Methods & Clinical Development

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Transgene, Genetic enhancement, MPTP primate model, Pharmacology, ProSavin, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Dopamine, Genetics, medicine, Molecular Biology, Aromatic L-amino acid decarboxylase, business.industry, MPTP, Dopaminergic, lentiviral vector, dopamine replacement, medicine.disease, gene therapy, 3. Good health, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Parkinson’s disease, Molecular Medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff879935805c22964cd0ef7e6b94d7d
https://pubmed.ncbi.nlm.nih.gov/31406701

المؤلفون: Caroline Jan, Koichi Hosomi, Emmanuel Brouillet, Christophe Pouzat, Kyriacos A. Mitrophanous, Edward S. Boyden, Xavier Drouot, Philippe Hantraye, J. F. Mangin, Romina Aron-Badin, J. Dauguet, Stéphane Palfi, S Senova, Isabelle Doignon, G. S. Ralph, L. Barnes, Frédéric Pain, Guillaume P. Dugué, C. Poupon, Hannah J Stewart

المساهمون: Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Imagerie et Modélisation en Neurobiologie et Cancérologie (IMNC (UMR_8165)), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Massachusetts Institute of Technology. Media Laboratory, Program in Media Arts and Sciences (Massachusetts Institute of Technology), Boyden, Edward

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.3362. ⟨10.1038/s41598-018-21486-8⟩
Scientific Reports, 2018, 8 (1), pp.3362. ⟨10.1038/s41598-018-21486-8⟩
Sci.Rep.
Sci.Rep., 2018, 8 (1), pp.3362. ⟨10.1038/s41598-018-21486-8⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Nature

مصطلحات موضوعية: 0301 basic medicine, Male, Deep brain stimulation, medicine.medical_treatment, Genetic Vectors, lcsh:Medicine, Action Potentials, Biology, Optogenetics, Article, 03 medical and health sciences, 0302 clinical medicine, Genes, Reporter, Subthalamic Nucleus, Transduction, Genetic, Biological neural network, medicine, Connectome, Animals, lcsh:Science, [PHYS]Physics [physics], Multidisciplinary, Opsins, lcsh:R, Lentivirus, Motor Cortex, Macaca mulatta, Magnetic Resonance Imaging, Neuromodulation (medicine), Transcranial magnetic stimulation, Subthalamic nucleus, 030104 developmental biology, nervous system, lcsh:Q, Nerve Net, Neuroscience, 030217 neurology & neurosurgery, Tractography

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45952bcc0a8fba50c84760e844330d08
http://europepmc.org/articles/PMC5820256

المؤلفون: Binoy Appukuttan, Tim Stout, Austen Yeager, Matt Hartzell, Trevor J. McFarland, Maria Parker, Vicky Scripps, Scott Ellis, Jessica Bellec, Kyriacos A. Mitrophanous, Thomas Hady

المصدر: Human Gene Therapy. 25:408-418

مصطلحات موضوعية: Primates, genetic structures, medicine.medical_treatment, Genetic Vectors, Green Fluorescent Proteins, Cornea, Corneal Transplantation, Neovascularization, Equine infectious anemia, Corneal Opacity, Immune system, Immune privilege, Transduction, Genetic, Genetics, medicine, Animals, Humans, Corneal Neovascularization, Angiostatins, Molecular Biology, Corneal transplantation, Angiostatin, biology, Genetic Therapy, biology.organism_classification, eye diseases, Endostatins, medicine.anatomical_structure, Immunology, Molecular Medicine, Rabbits, sense organs, medicine.symptom, Endostatin, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f72c1a03824f35c0f6d181c774d137
https://doi.org/10.1089/hum.2013.079

المؤلفون: Philip C. Buttery, Richard Harrop, Helene Lepetit, Claire Thiriez, Xavier Drouot, G. Scott Ralph, Jean Pascal Lefaucheur, Cherry Lucas, Philippe Le Corvoisier, Pippa A Radcliffe, Philippe Hantraye, Patrice Dolphin, Pierre Brugières, Hirokazu Iwamuro, Sarah L Mason, Olivier Rascol, Gilles Fénelon, David P. Breen, Inanna Gabriel, Sarah Deeley, Michelle Kelleher, Sonia Lavisse, Kou Abhay, Aurélie Kas, Stuart Naylor, Roger A. Barker, Jean Marc Gurruchaga, Pierre Cesaro, Natalie Valle Guzman, Stéphane Palfi, Colin Watts, Kyriacos A. Mitrophanous, Nicholas D. Mazarakis, Bijan Ghaleh, James Miskin, Philippe Remy, Naoki Tani, Susan M. Kingsman

المصدر: The Lancet. 383:1138-1146

مصطلحات موضوعية: Male, medicine.medical_specialty, Parkinson's disease, Tyrosine 3-Monooxygenase, Dopamine, Genetic Vectors, Injections, Intralesional, ProSavin, Transfection, Antiparkinson Agents, Internal medicine, Humans, Medicine, Transgenes, GTP Cyclohydrolase, Adverse effect, Aged, business.industry, Dopaminergic Neurons, Putamen, Dopaminergic, Parkinson Disease, Genetic Therapy, General Medicine, Middle Aged, medicine.disease, Surgery, Clinical trial, Tolerability, Dopa Decarboxylase, business, Follow-Up Studies, Infectious Anemia Virus, Equine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0a5babde8323ced726571ab8e4abb8
https://doi.org/10.1016/s0140-6736(13)61939-x

المؤلفون: Douglas J. Jolly, Maritza McIntyre, James Miskin, Joy A. Cavagnaro, Kyriacos A. Mitrophanous, Timothy K. MacLachlan

المصدر: Human Gene Therapy Clinical Development. 24:1-4

مصطلحات موضوعية: Drug, Pharmaceutical drug, Biodistribution, business.industry, media_common.quotation_subject, medicine.medical_treatment, Genetic enhancement, Genetic Vectors, Drug Evaluation, Preclinical, Guidelines as Topic, Genetic Therapy, Computational biology, Viral vector, Pharmacokinetics, Viruses, Immunology, Humans, Medicine, Tissue Distribution, Transgenes, Animal studies, business, Genetics (clinical), Drug metabolism, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949bb9cfe970c13ba59f1ff34e8c93ac
https://doi.org/10.1089/humc.2013.008

المؤلفون: Ian Blount, G. Scott Ralph, Kyriacos A. Mitrophanous, Stéphane Palfi, Laura McCloskey, Alan J. Kingsman, Owen Wells, Christelle J M Truran, Lucy Barnes, Liang Fong-Wong, Iain T. Strickland, Hannah J Stewart

المصدر: Human gene therapy. Clinical development. 27(3)

مصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, Genetic enhancement, Transgene, Dopamine, Recombinant Fusion Proteins, Genetic Vectors, Pharmacology, Biology, ProSavin, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Gene expression, medicine, Animals, Humans, Transgenes, Rats, Wistar, Genetics (clinical), Cells, Cultured, Neurons, Gene Transfer Techniques, Parkinson Disease, Genetic Therapy, medicine.disease, Molecular biology, Rats, 030104 developmental biology, Expression cassette, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443f99a5e506e4b9499cab7758a6bb7f
https://pubmed.ncbi.nlm.nih.gov/27470285

المؤلفون: Kyriacos A. Mitrophanous, Richard Bannister, Nerys E Evans, Marie A Leroux-Carlucci, D. Farley, James Miskin

المصدر: Human Gene Therapy Methods. 23:309-323

مصطلحات موضوعية: viruses, Genetic Vectors, Virus Replication, Applied Microbiology and Biotechnology, Virus, Cell Line, Viral vector, Equine infectious anemia, Mice, Transduction, Genetic, Gene Order, Murine leukemia virus, Genetics, Animals, Humans, Horses, Vector (molecular biology), Research Articles, Genetics (clinical), Pharmacology, biology, Reproducibility of Results, biology.organism_classification, Virology, Molecular biology, Leukemia Virus, Murine, Viral Tropism, Viral replication, Lentivirus, Tissue tropism, Molecular Medicine, Biological Assay, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953699c39dc30326ad021386e3f57f1c
https://doi.org/10.1089/hgtb.2012.102

المؤلفون: Liang Fong-Wong, G. Scott Ralph, Vinay Thoree, Michelle Kelleher, Iain T. Strickland, Kyriacos A. Mitrophanous, Hannah J Stewart, Pippa A Radcliffe, Laura Stevenson, Janine McCarthy, Daniel Chipchase

المصدر: Human Gene Therapy. 22:357-369

مصطلحات موضوعية: Male, Transcription, Genetic, Genetic enhancement, Genetic Vectors, Cell, Gene Dosage, Computational biology, Biology, Gene dosage, Genomic Instability, Cell Line, Viral vector, Equine infectious anemia, Industrial Microbiology, Transduction (genetics), Transduction, Genetic, Genetics, medicine, Animals, Humans, Transgenes, Vector (molecular biology), Rats, Wistar, Molecular Biology, HEK 293 cells, Brain, Parkinson Disease, Genetic Therapy, biology.organism_classification, Rats, HEK293 Cells, medicine.anatomical_structure, Immunology, Molecular Medicine, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbd4ab341a8a3e3de57397f33187d55
https://doi.org/10.1089/hum.2010.142

المؤلفون: C. D. Robertson, Kyriacos A. Mitrophanous, Jacqueline Smith, Adrian Sherman, Michael J. McGrew, P. Barnard, E. A. Elliot, Helen Sang, Pippa A Radcliffe, Simon G. Lillico, C. Haslam

المصدر: Lillico, S G, Sherman, A, McGrew, M J, Robertson, C D, Smith, J, Haslam, C, Barnard, P, Radcliffe, P A, Mitrophanous, K A, Elliot, E A & Sang, H M 2007, ' Oviduct-specific expression of two therapeutic proteins in transgenic hens ', Proceedings of the National Academy of Sciences, vol. 104, no. 6, pp. 1771-6 . https://doi.org/10.1073/pnas.0610401104

مصطلحات موضوعية: Male, Eggs, Transgene, Genetic Vectors, Egg protein, Oviducts, Animals, Genetically Modified, Mice, Egg White, medicine, Animals, Humans, Gene silencing, Ovum, Multidisciplinary, biology, Lentivirus, Egg Proteins, Gene Transfer Techniques, Interferon beta-1a, Interferon-beta, Biological Sciences, Molecular biology, Recombinant Proteins, Cell biology, Transgenesis, Ovalbumin, biology.protein, Oviduct, Female, Chickens, Infectious Anemia Virus, Equine, medicine.drug, Egg white

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09b1e3442649e4021cb3b883e3d357f
https://doi.org/10.1073/pnas.0610401104

المؤلفون: Binoy Appukuttan, Tim Stout, Kyriacos A. Mitrophanous, Khilan Shah, Maria Parker, Laura McCloskey, Scott Ellis, Trevor J. McFarland, Frank Larkin, Matt Hartzell, Vicky Kennedy, Simon Chandler

المصدر: Molecular Therapy. 23

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Angiostatin, genetic structures, business.industry, medicine.medical_treatment, medicine.disease, eye diseases, Neovascularization, medicine.anatomical_structure, Immune privilege, Ophthalmology, Cornea, Corneal neovascularization, Drug Discovery, medicine, Genetics, Molecular Medicine, sense organs, medicine.symptom, Endostatin, business, Molecular Biology, Ex vivo, Corneal transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da609a9ff5d85731fa5eccf1cbae2488