المؤلفون: Tadahiro Shinozawa, Koki Nakamura, Masanobu Shoji, Maya Morita, Maya Kimura, Hatsue Furukawa, Hiroki Ueda, Masanari Shiramoto, Kyoko Matsuguma, Yoshikazu Kaji, Ippei Ikushima, Makoto Yono, Shyh-Yuh Liou, Hirofumi Nagai, Atsushi Nakanishi, Keiji Yamamoto, Seigo Izumo

المصدر: Stem Cell Reports, Vol 8, Iss 2, Pp 226-234 (2017)

مصطلحات موضوعية: iPSC, cardiomyocytes, QT prolongation, drug susceptibility, clinical trial, inter-individual difference, drug safety assessment, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671116303046; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/a2998877a57c406ca455ead2f82a7a50

المؤلفون: Hiroki Noguchi, Keiji Kakumoto, Kyoko Matsuguma, Noriyuki Kohda, Takeshi Ikenaga, Tetsuya Yamamoto, 山本 徹也, 松隈 京子, 池永 武, 甲田 哲之, 角元 慶二, 野口 洋樹

المصدر: 痛風と尿酸・核酸 / Gout and Uric & Nucleic Acids. 2019, 43(1):56

المؤلفون: Eri KANDA, Eunhee CHUNG, Kazuichi NATORI, Kazuya ITO, Kei SAKAMOTO, Koji OGAWA, Kyoko MATSUGUMA, Makoto YONO, Masanari SHIRAMOTO, Miyuki KIMURA, Shin IRIE, Shunji MATSUKI, Takashi MATSUI, 伊藤 一弥, 入江 伸, 名取 和一, 坂本 慶, 小川 幸司, 木村 美由紀, 松井 隆, 松木 俊二, 松隈 京子, 白源 正成, 神田 英里, 米納 誠, 鄭 恩希

المصدر: 臨床薬理 / Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 2014, 45(4):151

المؤلفون: Hiroshi TSUKIKAWA, Kyoko MATSUGUMA, Shigeyuki NAKANO, Shin IRIE, Yukiko SUNAMI

المصدر: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 2007, 38(6):401

المؤلفون: Kyoko MATSUGUMA, Kyosuke YAMAMOTO, Miyoko TOKUSHIMA, Seiichiro TAKAKI, Shigetaka MATSUMOTO, Tateo KUNO, Yasuyuki IKEDA, 久野 建夫, 山本 匡介, 徳島 美代子, 松本 重孝, 松隈 京子, 池田 康行, 高木 誠一郎

المصدر: 動脈硬化 / The Journal of Japan Atherosclerosis Society. 1990, 18(6):671

المؤلفون: Kyoko Matsuguma, Susanna Eketjäll, Tatsuya Yoshihara, Fumihiko Azuma, Glen Hughes, Kei Sakamoto, Alan R. Kugler, Robert C. Alexander, Naoki Uchida, Muir Russell, Samantha Budd Haeberlein, Shunji Matsuki

المصدر: The Journal of Clinical Pharmacology. 57:1460-1471

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, business.industry, Healthy subjects, medicine.disease, Multiple dosing, Clinical trial, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cerebrospinal fluid, Orally active, Tolerability, Pharmacokinetics, medicine, Pharmacology (medical), Alzheimer's disease, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e7b8ab5558f619a1893ded62f15383ce
https://doi.org/10.1002/jcph.950

المؤلفون: Shunji Matsuki, Maiko Nomoto, Seiichiro Hojo, Hideto Akama, Kyoko Matsuguma, Fuminori Ohba, Shuhei Imayama

المصدر: Journal of Dermatological Treatment. 27:467-472

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Phosphodiesterase Type 4, Phthalic Acids, Dermatology, Administration, Cutaneous, Dermatitis, Atopic, Ointments, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, In patient, Phosphodiesterase inhibitor, PDE4 Inhibitors, Transdermal, Dose-Response Relationship, Drug, business.industry, Atopic dermatitis, medicine.disease, Bioavailability, Clinical trial, Treatment Outcome, 030104 developmental biology, Quinazolines, Phosphodiesterase 4 Inhibitors, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fa0ca6125dd331f67a92d0fc30a355
https://doi.org/10.3109/09546634.2016.1157257

المؤلفون: Hinako Uchimaru, Yoshikazu Kaji, Masanari Shiramoto, Shin Irie, Kyoko Matsuguma, Ippei Ikushima, Makoto Yonou, Shunji Matsuki

المصدر: Therapeutic innovationregulatory science. 48(2)

مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, business.industry, Population, Prolonged QT, Public Health, Environmental and Occupational Health, Assay sensitivity, Holter electrocardiogram, Crossover study, QT interval, Confidence interval, Moxifloxacin, Anesthesia, Internal medicine, Cardiology, Medicine, Pharmacology (medical), business, education, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8fec696373e6648c805e7010db1f99
https://pubmed.ncbi.nlm.nih.gov/30227503

المؤلفون: Miyuki Kimura, Daiki Kaneko, Shin Irie, Kei Sakamoto, Misato Nakagawa, Masanari Shiramoto, Kyoko Matsuguma, Akihiro Ohnishi, Shunji Matsuki

المصدر: Clinical Pharmacology in Drug Development. 4:99-104

مصطلحات موضوعية: business.industry, Area under the curve, Cmax, Pharmaceutical Science, Filgrastim, Pharmacology, Crossover study, Confidence interval, Pharmacokinetics, Pharmacodynamics, Absolute neutrophil count, Medicine, Pharmacology (medical), business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c213764d9cf4e02c8651c918e9facf9c
https://doi.org/10.1002/cpdd.178

المؤلفون: Mariko Morishita, Shin Irie, Naoki Kotani, Ichiro Ieiri, Yukie Ando, Hiroyuki Kusuhara, Tsuyoshi Okuzono, Noritomo Izumi, Eri Kanda, Kyoko Matsuguma, Shyohei Tsunemitsu, Naoe Yamane, Takeshi Hirota, Shunji Matsuki, Miyuki Kimura, Kazuya Maeda, Mariko Deguchi, Yuichi Sugiyama

المصدر: The Journal of Clinical Pharmacology. 53:654-661

مصطلحات موضوعية: Pharmacology, Fexofenadine, Chemistry, Pharmacokinetics, medicine, Midazolam, Pharmacology (medical), Terfenadine, Ritonavir, Dosing, Saquinavir, Pravastatin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::76cb7f182869193c960eb41613000165
https://doi.org/10.1002/jcph.62

المؤلفون: Kei, Sakamoto, Shunji, Matsuki, Kyoko, Matsuguma, Tatsuya, Yoshihara, Naoki, Uchida, Fumihiko, Azuma, Muir, Russell, Glen, Hughes, Samantha Budd, Haeberlein, Robert C, Alexander, Susanna, Eketjäll, Alan R, Kugler

المصدر: Journal of clinical pharmacology. 57(11)

مصطلحات موضوعية: Adult, Male, Amyloid beta-Peptides, Imidazoles, Brain, Middle Aged, Healthy Volunteers, Peptide Fragments, Amyloid beta-Protein Precursor, Plasma, Young Adult, Asian People, Double-Blind Method, Alzheimer Disease, Aspartic Acid Endopeptidases, Humans, Female, Spiro Compounds, Amyloid Precursor Protein Secretases, Aged, Cerebrospinal Fluid, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::87144b0fd598b9458837d9d210282b8d
https://pubmed.ncbi.nlm.nih.gov/28618005

المؤلفون: Alan R. Kugler, Glen Hughes, Muir Russell, Shunji Matsuki, Robert C. Alexander, Naoki Uchida, Kei Sakamoto, Kyoko Matsuguma, Samantha Budd Haeberlein, Tatsuya Yoshihara, Fumihiko Azuma

المصدر: Alzheimer's & Dementia. 12

مصطلحات موضوعية: Epidemiology, business.industry, Health Policy, Safety tolerability, Pharmacology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Cerebrospinal fluid, Developmental Neuroscience, Pharmacokinetics, Medicine, Neurology (clinical), Geriatrics and Gerontology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf2c1b99e45b684416023cbf8f71e175
https://doi.org/10.1016/j.jalz.2016.06.1206

المؤلفون: Shunji Matsuki, Masahiro Nomoto, Masanari Shiramoto, Kyoko Matsuguma, Jun Morita, Masashi Tanaka, Tomomi Tsuru

المصدر: Biodrugs

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Antineoplastic Agents, Bioequivalence, Pharmacology, 030226 pharmacology & pharmacy, law.invention, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Biosimilar Pharmaceuticals, Randomized controlled trial, Pharmacokinetics, Asian People, Double-Blind Method, Trastuzumab, law, Internal medicine, Medicine, Humans, Pharmacology (medical), Original Research Article, skin and connective tissue diseases, Infusions, Intravenous, neoplasms, business.industry, Immunogenicity, Follow up studies, Biosimilar, General Medicine, Therapeutic Equivalency, 030220 oncology & carcinogenesis, Area Under Curve, business, Biotechnology, medicine.drug, Follow-Up Studies, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956ce744f23dccca2d4ddf7e56a822e5
https://pubmed.ncbi.nlm.nih.gov/26691837

المؤلفون: Seiya Okuda, Sho-ichi Yamagishi, Seiya Kato, Kyoko Matsuguma, Tsutomu Imaizumi, Ryo Shibata, Utako Kaneyuki, Yuriko Matsumoto, Hidehiro Matsuoka, Masumi Kimoto, Seiji Ueda, Toshiko Fujimura

المصدر: Journal of the American Society of Nephrology. 17:2176-2183

مصطلحات موضوعية: Male, Nephrology, Protein-Arginine N-Methyltransferases, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Population, Renal function, Arginine, Kidney, Nephrectomy, Adenoviridae, Amidohydrolases, Rats, Sprague-Dawley, Pathogenesis, chemistry.chemical_compound, Internal medicine, medicine, Animals, education, education.field_of_study, biology, business.industry, General Medicine, medicine.disease, Rats, Nitric oxide synthase, Kinetics, Cholesterol, Endocrinology, Liver, chemistry, Hypertension, biology.protein, Kidney Failure, Chronic, Asymmetric dimethylarginine, business, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eb22542707e0d866fc59a3c0643891
https://doi.org/10.1681/asn.2005121379

المؤلفون: Shinichi Kikawa, Shin Irie, Atsuko Wanibuchi, Kyoko Matsuguma, Hidetoshi Furuie, Makoto Murakami

المصدر: Drug Metabolism and Pharmacokinetics. 20:337-344

مصطلحات موضوعية: Adult, Male, Hydrochloride, Morpholines, Adrenergic beta-Antagonists, Pharmaceutical Science, Blood Pressure, Pharmacology, Placebo, chemistry.chemical_compound, Double-Blind Method, Pharmacokinetics, Heart Rate, Dose escalation, Humans, Urea, Medicine, Pharmacology (medical), Dose-Response Relationship, Drug, business.industry, Landiolol, Regimen, Dose–response relationship, chemistry, Pharmacodynamics, Anesthesia, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda2b582a27e7ffaa50342b40079ef79
https://doi.org/10.2133/dmpk.20.337

المؤلفون: Miyuki Kimura, R. Hanada, Kyoko Matsuguma, Y. Sakata, Koki Furusho, Shunji Matsuki, M. Deguchi, Kei Sakamoto, E. Chung

المصدر: Clinical Therapeutics. 37:e28-e29

مصطلحات موضوعية: Pharmacology, Clinical trial, medicine.medical_specialty, Cerebrospinal fluid, business.industry, Medicine, Pharmacology (medical), Sampling (medicine), business, Intensive care medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::627dc8f96eaf3dfa2360772797581c9a
https://doi.org/10.1016/j.clinthera.2015.05.090

المؤلفون: Miyuki Kimura, Kyoko Matsuguma, Akiko Miyamoto, Asuka Tanaka, Hiromi Takeshita, Daiki Kaneko, Akihiro Ohnishi, Akimasa Watanabe, Chung Eunhee, Shin Irie, Kei Sakamoto, Akiko Hitaka, Shunji Matsuki, Kyoko Shigetome

المصدر: Drug development and industrial pharmacy. 41(3)

مصطلحات موضوعية: Adult, Male, Injections, Subcutaneous, Cmax, Pharmaceutical Science, Pharmacology, Bioequivalence, Filgrastim, Young Adult, Pharmacokinetics, Asian People, Double-Blind Method, Drug Discovery, Granulocyte Colony-Stimulating Factor, Medicine, Humans, Infusions, Intravenous, Biosimilar Pharmaceuticals, Cross-Over Studies, business.industry, Organic Chemistry, Crossover study, Healthy Volunteers, Clinical trial, Pharmacodynamics, Absolute neutrophil count, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfced790b0405fa5e3634165a6e1bf6c
https://pubmed.ncbi.nlm.nih.gov/24471477

المؤلفون: Kyoko, Matsuguma, Shunji, Matsuki, Kei, Sakamoto, Masanari, Shiramoto, Misato, Nakagawa, Miyuki, Kimura, Shin, Irie, Daiki, Kaneko, Akihiro, Ohnishi

المصدر: Clinical pharmacology in drug development. 4(2)

مصطلحات موضوعية: Adult, Male, Cross-Over Studies, Filgrastim, Antigens, CD34, Hematopoietic Stem Cells, Healthy Volunteers, Young Adult, Treatment Outcome, Asian People, Double-Blind Method, Japan, Therapeutic Equivalency, Area Under Curve, Granulocyte Colony-Stimulating Factor, Humans, Biosimilar Pharmaceuticals, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7bf5c223ace2b0d4beb6b56aceda0367
https://pubmed.ncbi.nlm.nih.gov/27128214

المؤلفون: Ichiro, Ieiri, Shyohei, Tsunemitsu, Kazuya, Maeda, Yukie, Ando, Noritomo, Izumi, Miyuki, Kimura, Naoe, Yamane, Tsuyoshi, Okuzono, Mariko, Morishita, Naoki, Kotani, Eri, Kanda, Mariko, Deguchi, Kyoko, Matsuguma, Shunji, Matsuki, Takeshi, Hirota, Shin, Irie, Hiroyuki, Kusuhara, Yuichi, Sugiyama

المصدر: Journal of clinical pharmacology. 53(6)

مصطلحات موضوعية: Adult, Male, Cross-Over Studies, Ritonavir, Dose-Response Relationship, Drug, Liver-Specific Organic Anion Transporter 1, Midazolam, Organic Anion Transporters, HIV Protease Inhibitors, Intestines, Young Adult, Liver, Tandem Mass Spectrometry, Area Under Curve, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Humans, Drug Interactions, ATP Binding Cassette Transporter, Subfamily B, Member 1, Terfenadine, Saquinavir, Chromatography, Liquid, Pravastatin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::04ce13d7dac15cd406d3ad7de8b6e49e
https://pubmed.ncbi.nlm.nih.gov/23381882

المؤلفون: Kazuhide Iwasaki, Masato Fukae, Kyoko Matsuguma, Shin Irie, Eri Kanda, Kazuya Maeda, Yuichi Sugiyama, Mariko Deguchi, Shunji Matsuki, Ichiro Ieiri, Miyuki Kimura, Yukie Ando, Takeshi Hirota, Takeshi Nakamura

المصدر: International journal of clinical pharmacology and therapeutics. 50(10)

مصطلحات موضوعية: Adult, Male, CYP2D6, Genotype, Microdosing, Lansoprazole, Administration, Oral, Organic Anion Transporters, CYP2C19, Pharmacology, Dextromethorphan, 2-Pyridinylmethylsulfinylbenzimidazoles, Young Adult, Therapeutic index, Pharmacokinetics, MicroDose, Glyburide, medicine, Humans, Pharmacology (medical), Cytochrome P-450 CYP2C9, business.industry, Cytochrome P-450 CYP2C19, Cytochrome P-450 CYP2D6, Area Under Curve, Aryl Hydrocarbon Hydroxylases, Warfarin, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece911e13e8d10c6e023f3a4a14e9ac4
https://pubmed.ncbi.nlm.nih.gov/22853867