المؤلفون: Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Paul D. Donohoue, Alexander H. Settle, Alexandra M. Lied, Kyle McGovern, Chris K. Fuller, Peter Cameron, Thomas G. Fazzio, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer

المصدر: Genome Biology, Vol 19, Iss 1, Pp 1-25 (2018)

مصطلحات موضوعية: Cas9, CRISPR, sgRNA, Protospacer adjacent motif, Off-target, Neisseria meningitidis, Biology (General), QH301-705.5, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13059-018-1591-1; https://doaj.org/toc/1474-760X

URL الوصول: https://doaj.org/article/d001df012bc241759e81c0e2bc14037f

المؤلفون: Kenneth Kim, Russell Dekelver, Anthony Conway, Matthew C. Mendel, Michael C. Holmes, Jeffrey C. Miller, Lei Zhang, Tom Redelmeier, Ying K. Tam, David Paschon, Kyle McGovern, Chris Barbosa, Paulo J. C. Lin, Alisa Boyko, Barbara L. Mui, Gary Lee

المصدر: Molecular Therapy. 27:866-877

مصطلحات موضوعية: Male, Transgene, Genetic Vectors, Biology, Gene Knockout Techniques, Mice, 03 medical and health sciences, PCSK9 Gene, Drug Delivery Systems, 0302 clinical medicine, Genome editing, Drug Discovery, Gene expression, Genetics, Animals, Prealbumin, RNA, Messenger, Transgenes, Molecular Biology, Cells, Cultured, 030304 developmental biology, Gene Editing, Pharmacology, 0303 health sciences, fungi, Intron, RNA, Dependovirus, Lipids, Zinc finger nuclease, Introns, Zinc Finger Nucleases, Cell biology, Mice, Inbred C57BL, 030220 oncology & carcinogenesis, Hepatocytes, Nanoparticles, Molecular Medicine, Female, Original Article, Proprotein Convertase 9

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af6d45484602776f4c7467ca7026daf
https://doi.org/10.1016/j.ymthe.2019.03.003

المؤلفون: Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Paul D. Donohoue, Alexander H. Settle, Alexandra M. Lied, Kyle McGovern, Chris K. Fuller, Peter Cameron, Thomas G. Fazzio, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer

مصطلحات موضوعية: 0303 health sciences, 03 medical and health sciences, Protospacer adjacent motif, 0302 clinical medicine, Genome editing, Cas9, CRISPR, Preprint, Computational biology, Biology, 030217 neurology & neurosurgery, 030304 developmental biology, Subgenomic mRNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf11545fa74e8cd6b7f7f61073629ac2
https://doi.org/10.1101/172650