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1Academic Journal
المؤلفون: Kale Kundert, James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin M. Heineike, Christina M. Fitzsimmons, Benjamin L. Oakes, Jiuxin Qu, Neha Prasad, Oren S. Rosenberg, David F. Savage, Hana El-Samad, Jennifer A. Doudna, Tanja Kortemme
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المصدر: Pathogens and Global Health
article-version (VoR) Version of Recordمصطلحات موضوعية: 0301 basic medicine, 030231 tropical medicine, 030106 microbiology, Review, Global Health, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Genome editing, diagnostics, Global health, genome editing, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, global health security, Gene Editing, Potential impact, Public Health, Environmental and Occupational Health, Outbreak, health, General Medicine, Infectious Diseases, Risk analysis (engineering), Infectious disease (medical specialty), Parasitology, Business, CRISPR-Cas Systems, biotechnology
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3
المؤلفون: Blake McMahon, Rachel J. Lew, Jennifer A. Doudna, Haridha Shivram, Christof Fellmann, Kyle E. Watters
المصدر: Proceedings of the National Academy of Sciences. 117:6531-6539
مصطلحات موضوعية: Genetics, 0303 health sciences, Multidisciplinary, biology, Inverted repeat, Cas9, biology.organism_classification, Genome, 3. Good health, Bacteriophage, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genome editing, chemistry, CRISPR, Gene, 030217 neurology & neurosurgery, DNA, 030304 developmental biology
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4
المؤلفون: Benjamin L. Oakes, Tanja Kortemme, Christof Fellmann, James E. Lucas, Kyle E. Watters, Jennifer A. Doudna, Hana El-Samad, Benjamin M. Heineike, Christina M. Fitzsimmons, Andrew H. Ng, David F. Savage, Oren S. Rosenberg, Neha K. Prasad, Kale Kundert, Jiuxin Qu
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Kundert, Kale; Lucas, James E; Watters, Kyle E; Fellmann, Christof; Ng, Andrew H; Heineike, Benjamin M; et al.(2019). Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs.. Nature communications, 10(1), 2127. doi: 10.1038/s41467-019-09985-2. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/3t52t2n5
Nature communications, vol 10, iss 1
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, CRISPR-Cas9 genome editing, Aptamer, Science, General Physics and Astronomy, 02 engineering and technology, Ligands, Aptamers, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Synthetic biology, CRISPR-Associated Protein 9, MD Multidisciplinary, Genetics, CRISPR, Guide RNA, lcsh:Science, Gene, Subgenomic mRNA, Gene Editing, Multidisciplinary, RNA, General Chemistry, DNA, Aptamers, Nucleotide, 021001 nanoscience & nanotechnology, Molecular conformation, Cell biology, 030104 developmental biology, chemistry, Generic Health Relevance, lcsh:Q, CRISPR-Cas Systems, 0210 nano-technology, Nucleotide, Guide, RNA, Guide, Kinetoplastida, Biotechnology
وصف الملف: application/pdf
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5
المؤلفون: Marco J. Lobba, Gavin J. Knott, Brittney W. Thornton, Jun-Jie Liu, Basem Al-Shayeb, Kyle E. Watters, Jennifer A. Doudna
المصدر: Nature structural & molecular biology, vol 26, iss 4
Knott, Gavin J; Thornton, Brittney W; Lobba, Marco J; Liu, Jun-Jie; Al-Shayeb, Basem; Watters, Kyle E; et al.(2019). Broad-spectrum enzymatic inhibition of CRISPR-Cas12a.. Nature structural & molecular biology, 26(4), 315-321. doi: 10.1038/s41594-019-0208-z. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/72n7n3pp
Nature structural & molecular biologyمصطلحات موضوعية: 1.1 Normal biological development and functioning, Biophysics, Adaptive Immunity, Cleavage (embryo), Medical and Health Sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genome editing, Structural Biology, Endoribonucleases, Genetics, CRISPR, Guide RNA, DNA Cleavage, Molecular Biology, 030304 developmental biology, Gene Editing, chemistry.chemical_classification, 0303 health sciences, Nuclease, biology, Biological Sciences, biology.organism_classification, Emerging Infectious Diseases, Enzyme, chemistry, Biochemistry, Chemical Sciences, biology.protein, Protein Multimerization, CRISPR-Cas Systems, 030217 neurology & neurosurgery, DNA, Bacteria, Developmental Biology
وصف الملف: application/pdf
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6
المؤلفون: Anthony T. Iavarone, Amina Asif, Simon Eitzinger, Gavin J. Knott, Jennifer A. Doudna, Kyle E. Watters, Fayyaz ul Amir Afsar Minhas
المصدر: Nucleic acids research, vol 48, iss 9
Nucleic Acids Researchمصطلحات موضوعية: Candidate gene, Proteome, Computer science, AcademicSubjects/SCI00010, Sequence analysis, Prophages, Bacterial genome size, Biology, Q1, Machine learning, computer.software_genre, Machine Learning, 03 medical and health sciences, Synthetic biology, Protein sequencing, Genome editing, Bacterial Proteins, Sequence Analysis, Protein, CRISPR-Associated Protein 9, Information and Computing Sciences, Genetics, CRISPR, Streptococcus iniae, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Cas9, business.industry, QH, Protein, 030302 biochemistry & molecular biology, Computational Biology, Streptococcus, Biological Sciences, biology.organism_classification, 3. Good health, Identification (information), Narese/24, Artificial intelligence, Mobile genetic elements, business, computer, Sequence Analysis, Environmental Sciences, Developmental Biology
وصف الملف: application/pdf
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7
المؤلفون: Kyle E, Watters, Haridha, Shivram, Christof, Fellmann, Rachel J, Lew, Blake, McMahon, Jennifer A, Doudna
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: musculoskeletal diseases, Gene Editing, anti-CRISPR, Staphylococcus aureus, Staphylococcus, Inverted Repeat Sequences, DNA, Biological Sciences, Biochemistry, HEK293 Cells, Bacterial Proteins, immune system diseases, CRISPR-Associated Protein 9, CRISPR, Humans, genome editing, Amino Acid Sequence, CRISPR-Cas Systems, Enzyme Inhibitors, self-targeting, skin and connective tissue diseases, Cas9, Conserved Sequence, Genome, Bacterial
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8
المؤلفون: Jennifer A. Doudna, Hua B. Bai, Shawn M. Ren, Christof Fellmann, Kyle E. Watters
المصدر: Watters, Kyle E; Fellmann, Christof; Bai, Hua B; Ren, Shawn M; & Doudna, Jennifer A. (2018). Systematic discovery of natural CRISPR-Cas12a inhibitors.. Science (New York, N.Y.), 362(6411), 236-239. doi: 10.1126/science.aau5138. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2vs8h2xs
Science (New York, N.Y.), vol 362, iss 6411مصطلحات موضوعية: 0301 basic medicine, General Science & Technology, Genomics, Computational biology, Genome, Article, Cell Line, Genome engineering, 03 medical and health sciences, 0302 clinical medicine, Bacterial Proteins, Genome editing, MD Multidisciplinary, Humans, Moraxella, CRISPR, DNA Cleavage, Gene Editing, Nuclease, Multidisciplinary, biology, Cas9, Bacterial, Computational Biology, Endonucleases, 030104 developmental biology, biology.protein, CRISPR-Cas Systems, Mobile genetic elements, Genome, Bacterial, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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9
المؤلفون: Kyle E. Watters, Jeremy R. Thompson, Julius B. Lucks, Keith L. Perry, Sharon Aviran, Krishna Choudhary
المصدر: Nucleic Acids Research
Nucleic acids research, vol 46, iss 5مصطلحات موضوعية: 0301 basic medicine, Untranslated region, Biology, Cucumovirus, Virus, Primer extension, Cucumber mosaic virus, 03 medical and health sciences, Information and Computing Sciences, Genetics, RNA and RNA-protein complexes, Viral, Nucleic acid structure, 030102 biochemistry & molecular biology, RNA, Biological Sciences, Reverse transcriptase, Open reading frame, 030104 developmental biology, Mutation, Nucleic Acid Conformation, RNA, Viral, Environmental Sciences, Developmental Biology
وصف الملف: application/pdf
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10
المؤلفون: Christof Fellmann, Haridha Shivram, Blake McMahon, Kyle E. Watters, Jennifer A. Doudna, Rachel J. Lew
المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 12
مصطلحات موضوعية: anti-CRISPR, Staphylococcus aureus, Inverted repeat, Staphylococcus, Computational biology, Biology, Genome, Bacteriophage, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Bacterial Proteins, Genome editing, CRISPR-Associated Protein 9, Genetics, Humans, genome editing, CRISPR, Amino Acid Sequence, Enzyme Inhibitors, Cas9, Gene, Conserved Sequence, 030304 developmental biology, Gene Editing, 0303 health sciences, Prevention, Inverted Repeat Sequences, Human Genome, Bacterial, DNA, biology.organism_classification, 3. Good health, HEK293 Cells, Emerging Infectious Diseases, Infectious Diseases, chemistry, 5.1 Pharmaceuticals, CRISPR-Cas Systems, self-targeting, Development of treatments and therapeutic interventions, Infection, 030217 neurology & neurosurgery, Biotechnology
وصف الملف: application/pdf
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11
المؤلفون: Julius B. Lucks, Angela M Yu, John T. Lis, Kyle E. Watters, Eric J. Strobel
المصدر: Nature structural & molecular biology
مصطلحات موضوعية: 0301 basic medicine, Riboswitch, RNA Folding, Transcription, Genetic, Computational biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Bacillus cereus, Structural Biology, Transcription (biology), RNA polymerase, Escherichia coli, Nucleic acid structure, Molecular Biology, Genetics, Signal recognition particle, Base Sequence, Chemistry, Escherichia coli Proteins, RNA, RNA, Bacterial, 030104 developmental biology, Terminator (genetics), Cobalamin riboswitch, Transcription Termination, Genetic, Mutation, Nucleic Acid Conformation, Signal Recognition Particle
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12
المؤلفون: Kyle E. Watters, Melissa K. Takahashi, Paul M. Gasper, Alan A. Chen, Julius B. Lucks, Timothy R. Abbott, Paul D. Carlson
المساهمون: Institute for Medical Engineering and Science (IMES), Takahashi, Melissa Kimie
المصدر: Cold Spring Harbor Laboratory Press
مصطلحات موضوعية: 0301 basic medicine, Genetics, Transcription, Genetic, 030102 biochemistry & molecular biology, In silico, RNA, Repressor, Gene Expression Regulation, Bacterial, Computational biology, Molecular Dynamics Simulation, Biology, Models, Biological, Article, Antisense RNA, RNA, Bacterial, 03 medical and health sciences, Synthetic biology, 030104 developmental biology, Mutation, Gene expression, Escherichia coli, Nucleic acid structure, Molecular Biology, Gene
وصف الملف: application/pdf
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13
المؤلفون: Kyle E. Watters, Angela M Yu, Julius B. Lucks, Eric J. Strobel, Alan A. Chen, Paul M. Gasper
مصطلحات موضوعية: 0303 health sciences, Signal recognition particle, Chemistry, Point mutation, RNA, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, 03 medical and health sciences, Molecular dynamics, Transcription (biology), Biophysics, Rna folding, Native structure, Protein secondary structure, 030304 developmental biology
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14
المؤلفون: Tanja Kortemme, Christof Fellmann, Benjamin L. Oakes, James E. Lucas, Benjamin M. Heineike, Christina M. Fitzsimmons, Kale Kundert, Jennifer A. Doudna, Andrew H. Ng, David F. Savage, Hana El-Samad, Kyle E. Watters
مصطلحات موضوعية: 0303 health sciences, Chemistry, Ligand, Cell biology, 03 medical and health sciences, Synthetic biology, chemistry.chemical_compound, 0302 clinical medicine, CRISPR, Guide RNA, Gene, 030217 neurology & neurosurgery, DNA, Function (biology), 030304 developmental biology, Subgenomic mRNA
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15
المؤلفون: Melissa K. Takahashi, Julius B. Lucks, James Chappell, Kyle E. Watters
المصدر: Current Opinion in Chemical Biology. 28:47-56
مصطلحات موضوعية: Regulation of gene expression, RNA Folding, Base Sequence, media_common.quotation_subject, Gene regulatory network, RNA, Computational biology, Biology, Molecular diagnostics, Biochemistry, Analytical Chemistry, Computers, Molecular, Synthetic biology, ComputingMethodologies_PATTERNRECOGNITION, Gene Expression Regulation, Gene expression, Animals, Humans, Gene Regulatory Networks, Synthetic Biology, Rna folding, Genetic Engineering, Function (engineering), media_common
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16
المؤلفون: Julius B. Lucks, Eric J. Strobel, Kyle E. Watters
مصطلحات موضوعية: Genetics, chemistry.chemical_classification, Streptavidin, Riboswitch, 0303 health sciences, RNA, Computational biology, Biology, Primer extension, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Transcription (biology), RNA polymerase, Nucleotide, Nucleic acid structure, 030217 neurology & neurosurgery, 030304 developmental biology
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17
المؤلفون: Kyle E. Watters, Julius B. Lucks
المصدر: RNA Structure Determination ISBN: 9781493964314
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Genetics, 030102 biochemistry & molecular biology, RNA, Computational biology, Reverse transcriptase, Primer extension, DNA sequencing, 03 medical and health sciences, 030104 developmental biology, chemistry, RNA editing, Complementary DNA, Nucleotide, Nucleic acid structure
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18
المؤلفون: Eric J. Strobel, Angela M Yu, Kyle E. Watters, Alex H. Settle, Julius B. Lucks
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, RNA Folding, Computer science, Acylation, Computational biology, Biology, 010402 general chemistry, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Article, Primer extension, Nucleic acid secondary structure, 03 medical and health sciences, In vivo, Molecule, Computer Simulation, Nucleotide, Molecular Biology, Cells, Cultured, DNA Primers, 030304 developmental biology, Genetics, chemistry.chemical_classification, 0303 health sciences, Base Sequence, Biochemistry, Genetics and Molecular Biology(all), Hydroxyl Radical, Sequence Analysis, RNA, Inverted Repeat Sequences, RNA, Small molecule, In vitro, 0104 chemical sciences, Folding (chemistry), 030104 developmental biology, chemistry, Rna folding, Function (biology)
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19
المصدر: Nucleic Acids Research
مصطلحات موضوعية: 0301 basic medicine, Riboswitch, RNA Folding, Transcription, Genetic, Base pair, Acylation, Biotin, Computational biology, Biology, Chemistry Techniques, Analytical, Primer extension, Deoxyribonuclease EcoRI, 03 medical and health sciences, chemistry.chemical_compound, Transcription (biology), Hydroxides, Genetics, Nucleic acid structure, Base Pairing, DNA Primers, Base Sequence, Sequence Analysis, RNA, Oligonucleotide, RNA, 030104 developmental biology, chemistry, Nucleic Acid Conformation, Methods Online, Streptavidin, DNA
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20
المؤلفون: Julius B. Lucks, Sarai Meyer, Melissa K. Takahashi, David Loughrey, James Chappell, Kyle E. Watters
المصدر: Biotechnology Journal
مصطلحات موضوعية: Riboswitch, Reviews, Computational biology, Biology, 010402 general chemistry, 01 natural sciences, Applied Microbiology and Biotechnology, 03 medical and health sciences, Synthetic biology, Transcription (biology), Gene expression, Non-coding RNA, RNA structure, 030304 developmental biology, Regulation of gene expression, Genetics, 0303 health sciences, RNA, General Medicine, 0104 chemical sciences, Gene regulation, Gene Expression Regulation, Regulatory sequence, Next-generation sequencing, Molecular Medicine, Synthetic Biology
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