المؤلفون: Kuo-Hao Lee, Gisela Andrea Camacho-Hernandez, Amy Hauck Newman, Lei Shi

المصدر: Biomolecules, Vol 14, Iss 6, p 713 (2024)

مصطلحات موضوعية: atypical DAT inhibitor, cocaine, dopamine transporter, inward-facing conformation, molecular dynamics, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/6/713; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/395b108d5c4d41e3abc6a00c9797e9a9

المؤلفون: J Robert Lane, Ara M Abramyan, Pramisha Adhikari, Alastair C Keen, Kuo-Hao Lee, Julie Sanchez, Ravi Kumar Verma, Herman D Lim, Hideaki Yano, Jonathan A Javitch, Lei Shi

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: dopamine d2 receptor, na+ sensitivity, inverse agonism, molecular dynamics, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/52189; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/22ae5702392642ec91760a357236acbd

المؤلفون: Amarachi V. Okorom, Gisela Andrea Camacho-Hernandez, Kristine Salomon, Kuo Hao Lee, Therese C. Ku, Jianjing Cao, Sung Joon Won, Jacob Friedman, Jenny Lam, James Paule, Rana Rais, Benjamin Klein, Zheng-Xiong Xi, Lei Shi, Claus J. Loland, Amy Hauck Newman

مصطلحات موضوعية: Biochemistry, Genetics, Neuroscience, Pharmacology, Biotechnology, Cancer, Mental Health, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, yl )- propan, shown therapeutic potential, rat liver microsomes, psychostimulant use disorders, previously reported analogues, piperidine ring system, negligible locomotor activity, jjc8 – 091, exhibit psychostimulant behaviors, ethyl )- piperazin, alkyl alicyclic amines, ol (< b, improve metabolic stability, 20a , 12b , metabolic stability, k <, , dat (<, well tolerated, sert )

Relation: https://figshare.com/articles/journal_contribution/Modifications_to_1_4-_2-Bis_4-fluorophenyl_methyl_sulfinyl_alkyl_Alicyclic_Amines_That_Improve_Metabolic_Stability_and_Retain_an_Atypical_DAT_Inhibitor_Profile/24878538

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c02037.s001
https://figshare.com/articles/journal_contribution/Modifications_to_1_4-_2-Bis_4-fluorophenyl_methyl_sulfinyl_alkyl_Alicyclic_Amines_That_Improve_Metabolic_Stability_and_Retain_an_Atypical_DAT_Inhibitor_Profile/24878538

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: 王子建

وصف الملف: 71

الاتاحة: http://ndltd.ncl.edu.tw/handle/8n83mb

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: Wen-Chun Tsai, 蔡文鈞

وصف الملف: 102

الاتاحة: http://ndltd.ncl.edu.tw/handle/f39yyj

المؤلفون: Kuo-hao Lee, 李國豪

Thesis Advisors: Kun-shan Chen, Yu-chiang Tzeng, 陳錕山, 曾裕強

وصف الملف: 70

الاتاحة: http://ndltd.ncl.edu.tw/handle/jeth2z

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: De-Hone Lin, 林德鴻

وصف الملف: 58

الاتاحة: http://ndltd.ncl.edu.tw/handle/18772736658000112978

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: Bore-Kuen Lee, 李柏坤

الاتاحة: http://ndltd.ncl.edu.tw/handle/35548546573358985660

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: Ying-Sheng Huang, 黃鶯聲

وصف الملف: 66

الاتاحة: http://ndltd.ncl.edu.tw/handle/42143367677379479155

المؤلفون: R. Benjamin Free (1316697), Ashley N. Nilson (14312793), Noelia M. Boldizsar (14312796), Trevor B. Doyle (14312799), Ramona M. Rodriguiz (185135), Vladimir M. Pogorelov (133492), Mayako Machino (14312802), Kuo Hao Lee (8436282), Jeremiah W. Bertz (14312805), Jinbin Xu (33400), Herman D. Lim (1655842), Andrés E. Dulcey (1316673), Robert H. Mach (279778), James H. Woods (1290507), J Robert Lane (12503554), Lei Shi (8144), Juan J. Marugan (191299), William C. Wetsel (185139), David R. Sibley (1618657)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Cancer, Science Policy, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, thus indicating exceptional, receptor binding rates, orthosteric binding site, human primates demonstrated, functional profiling screens, dopamine receptor antagonist, 168 different gpcrs, pet imaging studies, kinetic studies revealed, approved d2r antagonists, ml321 exhibits slow, induced locomotor activity, 2 , novel d2r antagonist, vivo <, ppi studies, taken together, selectively antagonize, restored pre, relatively ineffective, rats demonstrate

Relation: https://figshare.com/articles/journal_contribution/Identification_and_Characterization_of_ML321_A_Novel_and_Highly_Selective_D_sub_2_sub_Dopamine_Receptor_Antagonist_with_Efficacy_in_Animal_Models_That_Predict_Atypical_Antipsychotic_Activity/21799104

الاتاحة: https://doi.org/10.1021/acsptsci.2c00202.s001

المؤلفون: Kuo-Hao Lee, 李國豪

Thesis Advisors: 蔡雪芳

وصف الملف: 109

الاتاحة: http://ndltd.ncl.edu.tw/handle/56473308809763476184

المؤلفون: Anver Basha Shaik (7500401), Comfort A. Boateng (3617120), Francisco O. Battiti (10830442), Alessandro Bonifazi (1322385), Jianjing Cao (1307898), Li Chen (5749), Rezvan Chitsazi (4751388), Saiprasad Ravi (11551926), Kuo Hao Lee (8436282), Lei Shi (8144), Amy Hauck Newman (1307901)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, sterically bulky groups, require long linkers, molecular models confirmed, structure activity relationships, r bioconjugate tools, >- alkyl groups, position modifications would, 33 , 11 , r binding affinities, pyrrolidine ring system, >- alkylated compounds, 3 nm ), 3 , receptor bitopic ligands, 2 , bitopic ligands, pyrrolidine ring, >- alkylated, n <, improved affinities, crystal structure

Relation: https://figshare.com/articles/journal_contribution/Structure_Activity_Relationships_for_a_Series_of_Eticlopride-Based_Dopamine_D_sub_2_sub_D_sub_3_sub_Receptor_Bitopic_Ligands/16797486

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01353.s001

المؤلفون: R. Benjamin Free, Ashley N. Nilson, Noelia M. Boldizsar, Trevor B. Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov, Mayako Machino, Kuo Hao Lee, Jeremiah W. Bertz, Jinbin Xu, Herman D. Lim, Andrés E. Dulcey, Robert H. Mach, James H. Woods, J Robert Lane, Lei Shi, Juan J. Marugan, William C. Wetsel, David R. Sibley

المصدر: ACS Pharmacology & Translational Science. 6:151-170

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::02a97836fc59cbf3baf728f6990d1723
https://doi.org/10.1021/acsptsci.2c00202

المؤلفون: Shike Wang, Kuo-Hao Lee, Nathalia Victoria Araujo, Chang-Guo Zhan, Vivek M. Rangnekar, Ren Xu

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 18; Pages: 6613

مصطلحات موضوعية: prolyl hydroxylation, collagen, high-throughput screening, extracellular matrix, cancer invasion

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms21186613

الاتاحة: https://doi.org/10.3390/ijms21186613

المؤلفون: Collin J. Wilkinson, Kuo-Hao Lee, Danqi Yin, John C. Mauro

المصدر: MRS Communications. 12:1060-1066

مصطلحات موضوعية: General Materials Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d12fb63a9ece03ae739b3d3d6f40c1bd
https://doi.org/10.1557/s43579-022-00195-4

المؤلفون: John C. Mauro, Yongjian Yang, Benedikt Ziebarth, Linfeng Ding, Kuo-Hao Lee

المصدر: Journal of the American Ceramic Society. 105:2536-2545

مصطلحات موضوعية: Fracture toughness, Materials science, Cabin pressurization, Borosilicate glass, Materials Chemistry, Ceramics and Composites, Composite material

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7e488e1d7c08813a1c3f36c69f944f72
https://doi.org/10.1111/jace.18207

المؤلفون: Alessandro Bonifazi, Comfort A. Boateng, Francisco O. Battiti, Amy Hauck Newman, Jianjing Cao, Saiprasad Ravi, Kuo Hao Lee, Anver Basha Shaik, Lei Shi, Rezvan Chitsazi, Li Chen

المصدر: Journal of Medicinal Chemistry. 64:15313-15333

مصطلحات موضوعية: chemistry.chemical_compound, Eticlopride, Molecular model, Stereochemistry, Dopamine receptor D3, Chemistry, Dopamine receptor D2, Drug Discovery, Molecular Medicine, Pharmacophore, Linker, Affinities, Pyrrolidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::03167bb15eeae9f2fd9ae627de73ecf4
https://doi.org/10.1021/acs.jmedchem.1c01353

المؤلفون: R. Benjamin Free, Ashley N. Nilson, Noelia M. Boldizsar, Trevor B. Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov, Mayako Machino, Kuo Hao Lee, Jeremiah W. Bertz, Jinbin Xu, Herman D. Lim, Andrés E. Dulcey, Robert H. Mach, James H. Woods, J Robert Lane, Lei Shi, Juan J. Marugan, William C. Wetsel, David R. Sibley

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::54a0f9a844dff00ad9e58ab05b7c6477
https://doi.org/10.1101/2022.11.14.516475

المؤلفون: Joslyn Jung, Soren Wacker, Andrew D. Fant, Jiqing Guo, Williams E. Miranda, Mary Kudaibergenova, Sergei Y. Noskov, Henry J. Duff, Lei Shi, Andy Guan, Jianjing Cao, Kuo Hao Lee, Amy Hauck Newman, Therese Ku

المصدر: J Chem Inf Model

مصطلحات موضوعية: Models, Molecular, Quantitative structure–activity relationship, Molecular model, General Chemical Engineering, hERG, Library and Information Sciences, Machine learning, computer.software_genre, Ether, Article, Reuptake, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, Cocaine, Dopamine, medicine, Humans, 030304 developmental biology, Dopamine transporter, Dopamine Plasma Membrane Transport Proteins, 0303 health sciences, biology, business.industry, Mechanism (biology), Chemistry, food and beverages, General Chemistry, Potassium channel, 3. Good health, Computer Science Applications, biology.protein, Artificial intelligence, business, computer, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2210ef7eba1109d021c6032ff145c0da
https://doi.org/10.1021/acs.jcim.1c00856

المؤلفون: John C. Mauro, Caio Barca Bragatto, Collin J. Wilkinson, Kuo Hao Lee, Madoka Ono, Rebecca S. Welch

المصدر: Journal of the American Ceramic Society. 104:6183-6193

مصطلحات موضوعية: Molecular dynamics, chemistry.chemical_compound, Materials science, chemistry, Chemical engineering, Materials Chemistry, Ceramics and Composites, Hardening (metallurgy), chemistry.chemical_element, Calcium aluminosilicate, Oxygen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c244a5de49d6626ee1f0b4f59bd68ad9
https://doi.org/10.1111/jace.18032