يعرض 1 - 20 نتائج من 33 نتيجة بحث عن '"Kun-Hui Lu"', وقت الاستعلام: 0.74s تنقيح النتائج
  1. 1
    Academic Journal
    Supplementary Synthetic Methods from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/journal_contribution/Supplementary_Synthetic_Methods_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324615

    الاتاحة: https://doi.org/10.1158/2159-8290.25324615.v1
    https://figshare.com/articles/journal_contribution/Supplementary_Synthetic_Methods_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324615

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  2. 2
    Academic Journal
    Supplementary Table 1 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/journal_contribution/Supplementary_Table_1_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324612

    الاتاحة: https://doi.org/10.1158/2159-8290.25324612.v1
    https://figshare.com/articles/journal_contribution/Supplementary_Table_1_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324612

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  3. 3
    Academic Journal
    Supplementary Figures 1-14 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/journal_contribution/Supplementary_Figures_1-14_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324618

    الاتاحة: https://doi.org/10.1158/2159-8290.25324618.v1
    https://figshare.com/articles/journal_contribution/Supplementary_Figures_1-14_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324618

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  4. 4
    Dissertation/ Thesis
    Targeting signaling molecule, p110δ, to interfere B-1 functions for potential therapy against murine systemic lupus erythematosus
    全身性紅斑狼瘡之可能療法—藉由抑制p110δ訊息傳遞分子干擾B-1細胞之功能

    المؤلفون: Kun-Hui Lu, 呂昆輝

    Thesis Advisors: Bor-Luen Chiang, 江伯倫

    وصف الملف: 86

    الاتاحة: http://ndltd.ncl.edu.tw/handle/10406750147026610742

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  5. 5
    Dissertation/ Thesis
    Calibration of Default Probability in Credit Risk with Normal Test
    信用風險違約機率校準之NormalTest探討

    المؤلفون: Kun-Hui Lu, 盧昆輝

    Thesis Advisors: Ming-Chin Hung, Yi-Ping Chang, 洪明欽, 張揖平

    وصف الملف: 40

    الاتاحة: http://ndltd.ncl.edu.tw/handle/85149631901149942548

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  6. 6
    Supplementary Table 2 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/dataset/Supplementary_Table_2_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324609

    الاتاحة: https://doi.org/10.1158/2159-8290.25324609.v1
    https://figshare.com/articles/dataset/Supplementary_Table_2_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324609

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  7. 7
    Image
    Figure 5 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_5_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324624

    الاتاحة: https://doi.org/10.1158/2159-8290.25324624.v1
    https://figshare.com/articles/figure/Figure_5_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324624

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  8. 8
    Image
    Figure 6 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_6_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324621

    الاتاحة: https://doi.org/10.1158/2159-8290.25324621.v1
    https://figshare.com/articles/figure/Figure_6_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324621

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  9. 9
    Image
    Figure 2 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_2_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324633

    الاتاحة: https://doi.org/10.1158/2159-8290.25324633.v1
    https://figshare.com/articles/figure/Figure_2_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324633

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  10. 10
    Image
    Figure 3 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_3_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324630

    الاتاحة: https://doi.org/10.1158/2159-8290.25324630.v1
    https://figshare.com/articles/figure/Figure_3_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324630

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  11. 11
    Image
    Figure 1 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_1_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324636

    الاتاحة: https://doi.org/10.1158/2159-8290.25324636.v1

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  12. 12
    Image
    Figure 4 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

    المؤلفون: Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T. Chan, Kun-Hui Lu, Christabella A. Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C. Watt, Sunil Kumar Matsa, John Bisi, Jay Strum, Patrick Roberts, Shom Goel

    مصطلحات موضوعية: Cancer, Molecular and Cellular Biology, Therapeutic Research and Development, Breast Cancer, Cell Cycle, Cell cycle checkpoints, Cell Death And Senescence, Drug Mechanisms, Cell cycle mechanisms of anticancer drug action, Gastrointestinal Cancers, Stomach cancer, Gynecological Cancers, Small Molecule Agents, Kinase inhibitors, Translational Research

    Relation: https://figshare.com/articles/figure/Figure_4_from_INX-315_a_Selective_CDK2_Inhibitor_Induces_Cell_Cycle_Arrest_and_Senescence_in_Solid_Tumors/25324627

    الاتاحة: https://doi.org/10.1158/2159-8290.25324627.v1

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  13. 13
    PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity

    المؤلفون: Tony Tiganis, Pei Kee Goh, Chrysovalantou E. Xirouchaki, Spencer Greatorex, Kevin Sek, Paul A. Beavis, Rachel Xu, Xin Du, Samuel J. Hogarth, Phillip K. Darcy, Mara N. Zeissig, Kun-Hui Lu, Roger J. Daly, Florian Wiede, Nicholas K. Tonks

    المصدر: Cancer Discov

    مصطلحات موضوعية: T cell, Programmed Cell Death 1 Receptor, Cell, Cell- and Tissue-Based Therapy, CD8-Positive T-Lymphocytes, Immunotherapy, Adoptive, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Cytotoxicity, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Blockade, medicine.anatomical_structure, Oncology, Cancer research, hormones, hormone substitutes, and hormone antagonists, CD8, Intracellular

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe8179c7b63b6bcc3c67dfaef438480
    https://doi.org/10.1158/2159-8290.cd-21-0694

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  14. 14
    Data from PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity

    المؤلفون: Tony Tiganis, Nicholas K. Tonks, Phillip K. Darcy, Paul A. Beavis, Roger J. Daly, Kevin Sek, Spencer Greatorex, Samuel J. Hogarth, Chrysovalantou E. Xirouchaki, Pei Kee Goh, Rachel Xu, Mara N. Zeissig, Xin Du, Kun-Hui Lu, Florian Wiede

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e751b3f7f88629ae3ff63080275333a
    https://doi.org/10.1158/2159-8290.c.6549505

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  15. 15
    471 Transient inhibition of cyclin-dependent kinase 4/6 with trilaciclib enhances inhibitory receptor immunotherapy to improve antitumor efficacy

    المؤلفون: Kun-Hui Lu, Catherine Dietrich, Sarah Ahn, Subing Cao, John Yi, Shom Goel

    المصدر: Regular and Young Investigator Award Abstracts.

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::879e447731d2e4223ed6073398574826
    https://doi.org/10.1136/jitc-2022-sitc2022.0471

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  16. 16
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

    المؤلفون: Mara N. Zeissig, Spencer Greatorex, Chrysovalantou E. Xirouchaki, Nicholas K. Tonks, Kevin Sek, Rachel Xu, Pei Kee Goh, Samuel J. Hogarth, Paul A. Beavis, Roger J. Daly, Florian Wiede, Phillip K. Darcy, Xin Du, Tony Tiganis, Kun-Hui Lu

    مصطلحات موضوعية: medicine.anatomical_structure, Downregulation and upregulation, Chemistry, Immunity, T cell, Cell, Cancer research, medicine, Cytotoxicity, hormones, hormone substitutes, and hormone antagonists, Intracellular, CD8, Blockade

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8094c4f372999a9062c30382b8ebf209
    https://doi.org/10.1101/2021.11.11.468140

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  17. 17
    Transforming growth factor β in breast cancer: another new trick for the old dog

    المؤلفون: Kun-Hui Lu, Shom Goel

    المصدر: Nature

    مصطلحات موضوعية: 0301 basic medicine, biology, Mechanism (biology), Immunology, food and beverages, Breast Neoplasms, Cell Biology, Transforming growth factor beta, medicine.disease, Article, Blockade, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Breast cancer, Transforming Growth Factor beta, Cancer research, biology.protein, medicine, Humans, Immunology and Allergy, Female, Tumor growth, 030215 immunology, Transforming growth factor

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d170c8c6127ef69406773a9243df57
    https://doi.org/10.1111/imcb.12421

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  18. 18
    PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

    المؤلفون: Conor J. Kearney, Jason Waithman, Pei K Goh, Paul A. Beavis, Melissa A. Henderson, Shuwei Liang, Sheng Zhang, Xin Du, Simone L Park, Kun-Hui Lu, Florian Wiede, Thomas Gebhardt, Zhong Yin Zhang, Tony Tiganis, Phillip K. Darcy, Katharina Hochheiser, Deborah Meyran, Garron T. Dodd, Jane Oliaro

    المصدر: The EMBO Journal

    مصطلحات موضوعية: Male, Adoptive cell transfer, Receptor, ErbB-2, TCR signalling, STAT‐5 signalling, Immunology, Receptors, Antigen, T-Cell, Mice, Transgenic, Biology, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Immunotherapy, Adoptive, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Immunity, Neoplasms, adoptive T‐cell therapy, Animals, Humans, Src family kinase, Molecular Biology, 030304 developmental biology, Cancer, Mice, Knockout, 0303 health sciences, Antigen Presentation, Protein Tyrosine Phosphatase, Non-Receptor Type 2, CAR T cells, General Immunology and Microbiology, General Neuroscience, protein tyrosine phosphatase N2, Articles, Adoptive Transfer, Chimeric antigen receptor, 3. Good health, Immunosurveillance, Cancer research, CXCL9, Female, 030217 neurology & neurosurgery, CD8, Homing (hematopoietic), Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ad12b92d22774459ce78b726dccfd4
    https://pubmed.ncbi.nlm.nih.gov/31803974

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  19. 19
    PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours

    المؤلفون: Kun-Hui Lu, Conor J. Kearney, Garron T. Dodd, Jason Waithman, Jane Oliaro, Phillip K. Darcy, Paul A. Beavis, Florian Wiede, Tony Tiganis, Sheng Zhang, Conor Kearny, Deborah Meyran, Katharina Hochheiser, Pei K Goh, Melissa A. Henderson, Zhong Yin Zhang, Xin Du, Thomas Gebhardt, Shuwei Liang, Simone L Park

    مصطلحات موضوعية: Immunosurveillance, Adoptive cell transfer, medicine.anatomical_structure, business.industry, Immunity, T cell, Cancer research, Medicine, Src family kinase, business, CD8, Chimeric antigen receptor, Homing (hematopoietic)

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c9eafd64112d3c02fed6c790e7a15d

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  20. 20
    Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells

    المؤلفون: Jürgen Wienands, Thomas Oellerich, Tony Pawson, Facundo D. Batista, Anna Tafuri, Angelo Castello, Kun-Hui Lu, Johannes Tucholski, Michael Engelke, Mauro Gaya

    المصدر: Nature Immunology. 14:966-975

    مصطلحات موضوعية: 0303 health sciences, Chemistry, Proto-Oncogene Proteins c-akt, Kinase, Immunology, breakpoint cluster region, Signal transducing adaptor protein, 3. Good health, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Immunology and Allergy, Phosphorylation, Tyrosine, Signal transduction, PI3K/AKT/mTOR pathway, 030304 developmental biology, 030215 immunology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f05d9a827974bbb90fc7382445740d8
    https://doi.org/10.1038/ni.2685

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