المؤلفون: Thomas Horn, Kumar Reddy Kakularam, Monika Anton, Constanze Richter, Pallu Reddanna, Hartmut Kuhn

المصدر: Redox Biology, Vol 1, Iss 1, Pp 566-577 (2013)

مصطلحات موضوعية: Eicosanoids, Leukotrienes, Lipoxygenases, Gene polymorphism, SNP, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231713000815; https://doaj.org/toc/2213-2317

URL الوصول: https://doaj.org/article/abcbe4f4dcdf424e8c6889e3289c51e6

المؤلفون: Ashish Gupta, Neha Chaudhary, Kumar Reddy Kakularam, Reddanna Pallu, Aparoy Polamarasetty

المصدر: PLoS ONE, Vol 10, Iss 8, p e0134472 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4549307?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3d1e804da3d64a6a8fb1738a7345747f

المؤلفون: Kumar Reddy Kakularam, Felix Karst, Aparoy Polamarasetty, Igor Ivanov, Dagmar Heydeck, Hartmut Kuhn

المصدر: Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112434- (2022)

مصطلحات موضوعية: Eicosanoids, Lipoxygenase, Inhibitors, Leukotrienes, Resolvins, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332221012208; https://doaj.org/toc/0753-3322; https://doaj.org/article/ceedff28c8c34ca48c9278f1abd92056

الاتاحة: https://doi.org/10.1016/j.biopha.2021.112434
https://doaj.org/article/ceedff28c8c34ca48c9278f1abd92056

المؤلفون: Harshavardhan Bhuktar, Sharda Shukla, Kumar Reddy Kakularam, Srikanth Battu, Manupati Srikanth, Susmita Srivastava, Raghavender Medishetti, Pooja Ram, P.C. Jagadish, Mahaboobkhan Rasool, Sandipan Chakraborty, Nooruddin Khan, Pallu Reddanna, Srinivas Oruganti, Manojit Pal

المصدر: Bioorganic Chemistry. 138:106606

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa1113554b37837d4a68cc0b8774611c
https://doi.org/10.1016/j.bioorg.2023.106606

المؤلفون: Dagmar Heydeck, Sabine Stehling, Kumar Reddy Kakularam, Hartmut Kühn, Florian Reisch

المصدر: The FEBS Journal. 288:1387-1406

مصطلحات موضوعية: 0301 basic medicine, Oceans and Seas, Lipoxygenase, Gene Expression, Biology, fatty acids, Biochemistry, Genome, ALOXE3, Substrate Specificity, Evolution, Molecular, 03 medical and health sciences, 0302 clinical medicine, Species Specificity, evolution, oxidative stress, Animals, Arachidonate 15-Lipoxygenase, Seawater, Amino Acids, Molecular Biology, Gene, Mammals, Genetics, Arachidonic Acid, myr, Cell Biology, Evolutionary pressure, lipoxygenases, Adaptation, Physiological, Stop codon, ALOX15, Open reading frame, 030104 developmental biology, Prostaglandin-Endoperoxide Synthases, 030220 oncology & carcinogenesis, Mutation, Eicosanoids, epidermal differentiation, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a266855a6851b12f3f9ac52cbf90a08
https://doi.org/10.1111/febs.15469

المؤلفون: Kumar Reddy Kakularam, Dagmar Heydeck, Igor Ivanov, Hartmut Kühn, Aparoy Polamarasetty, Felix Karst

المصدر: Biomedicine & Pharmacotherapy, Vol 145, Iss, Pp 112434-(2022)

مصطلحات موضوعية: Gene isoform, Leukotrienes, animal structures, Lipoxygenase, RM1-950, Cell Line, Mice, Species Specificity, Sf9 Cells, Animals, Arachidonate 15-Lipoxygenase, Humans, Resolvins, Lipoxygenase Inhibitors, Pharmacology, chemistry.chemical_classification, biology, Inhibitors, ALOX15B, fungi, General Medicine, Lipid signaling, ALOX15, Isoenzymes, Enzyme, ALOX12, Biochemistry, chemistry, biology.protein, Eicosanoids, Human genome, Therapeutics. Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8d8cf08c07eecf4c671571907f1e04
https://pubmed.ncbi.nlm.nih.gov/34801853

المؤلفون: Hartmut Kühn, Dagmar Heydeck, Michael Rothe, Elena V. Shmendel, Kumar Reddy Kakularam, Polamarasetty Aparoy, Igor Ivanov

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1866:158918

مصطلحات موضوعية: 0301 basic medicine, Lipoxygenase, Substrate Specificity, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Catalytic Domain, Animals, Humans, Molecular Biology, chemistry.chemical_classification, biology, ALOX15B, Cell Biology, Lipid signaling, Anandamide, Endocannabinoid system, Isoenzymes, Molecular Docking Simulation, Oxygen, 030104 developmental biology, Enzyme, chemistry, ALOX12, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins), Arachidonic acid, 030217 neurology & neurosurgery, Endocannabinoids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6d323a5910bd1b546cf8741a9a1eb9
https://doi.org/10.1016/j.bbalip.2021.158918

المؤلفون: Polamarasetty Aparoy, Pallu Reddanna, Omkar Singh, Kumar Reddy Kakularam

المصدر: Protein & Peptide Letters. 22:903-912

مصطلحات موضوعية: Sulfonamides, Cyclooxygenase 2 Inhibitors, biology, Chemistry, Stereochemistry, Carbonic anhydrase II, Active site, General Medicine, Carbonic Anhydrase II, Biochemistry, Molecular Docking Simulation, Structure-Activity Relationship, chemistry.chemical_compound, Polmacoxib, Cyclooxygenase 2, Structural Biology, Docking (molecular), Carbonic anhydrase, biology.protein, Humans, Structure–activity relationship, Pharmacophore, Carbonic Anhydrase Inhibitors, Furans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc6f763e128cf75bcbc71f8f8ad45c9
https://doi.org/10.2174/0929866522666150622102131

المؤلفون: Hartmut Kühn, Dagmar Heydeck, Kumar Reddy Kakularam, Susan Adel, Thomas Horn, Pallu Reddanna

المصدر: Archives of Biochemistry and Biophysics. 565:17-24

مصطلحات موضوعية: Genetics, Leukotrienes, Genome, Human, Biophysics, Lipoxygenases, Subspecies, Biology, biology.organism_classification, Biochemistry, Genome, ALOXE3, Species Specificity, Homo sapiens, Databases, Genetic, Animals, Humans, Human genome, 1000 Genomes Project, Molecular Biology, Gene, Denisovan, Neanderthals, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf56974a5bdb25170fca82c1cbb5fc41
https://doi.org/10.1016/j.abb.2014.10.012

المؤلفون: Hartmut Kühn, Aparoy Polymarasetty, Katharina Hofheinz, Thomas Horn, Pallu Reddanna, Susan Adel, Monika Anton, Kumar Reddy Kakularam

المصدر: Archives of Biochemistry and Biophysics. 530:40-47

مصطلحات موضوعية: Models, Molecular, Structural similarity, Molecular Sequence Data, Biophysics, Inflammation, Biology, Biochemistry, Isozyme, Substrate Specificity, Mice, chemistry.chemical_compound, Biosynthesis, Catalytic Domain, Hydroxyeicosatetraenoic Acids, medicine, Animals, Humans, Amino Acid Sequence, Molecular Biology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, Lipid signaling, Recombinant Proteins, Amino acid, ALOX15, Enzyme, chemistry, Mutation, Mutagenesis, Site-Directed, medicine.symptom, Sequence Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20699777cb65d6c854c586bf1ccf5789
https://doi.org/10.1016/j.abb.2012.11.015

المؤلفون: Kumar Reddy Kakularam, Thomas Horn, Aparoy Polamarasetty, Pallu Redanna, Dagmar Heydeck, Saubashya Sur, Susan Adel, Hartmut Kühn, Ralf R. Schumann

المصدر: Progress in Lipid Research

مصطلحات موضوعية: Gene isoform, Tx, thromboxane, Leukotrienes, LX, lipoxins, Evolution, GGT, gamma-glutamyltranspeptidase, Lipoxygenase, AA, arachidonic acid, DHA, 4,7,10,13,16,19-docosahexaenoic acid, Bya, billion years ago, Biochemistry, Article, Evolution, Molecular, LTA4H, leukotriene A4 hydrolase, cPLA2, cytosolic phospholipase 2, LTC4S, leukotriene C4 synthase, Animals, Humans, Receptor, EPA, 5,8,11,14,17-eicosapentaenoic acid, Phylogeny, LOX, lipoxygenase, chemistry.chemical_classification, Genetics, Receptors, Leukotriene, Mya, million years ago, Leukotriene, biology, PG, prostaglandins, Gene polymorphisms, Genetic Variation, DPEP, dipeptidase, Cell Biology, Lipid signaling, Lipoxygenases, biology.organism_classification, RS, resolvins, COX, cyclooxygenase, Multicellular organism, Enzyme, chemistry, Vertebrates, biology.protein, Eicosanoids, Bacteria, Signal Transduction, SNPs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26a65bc0f48c4dd1381988e45e84bc8
https://pubmed.ncbi.nlm.nih.gov/25435097

المؤلفون: Hartmut Kühn, Monika Anton, Kumar Reddy Kakularam, Constanze Richter, Thomas Horn, Pallu Reddanna

المصدر: Redox Biology
Redox Biology, Vol 1, Iss 1, Pp 566-577 (2013)

مصطلحات موضوعية: Models, Molecular, Leukotrienes, Protein Conformation, Clinical Biochemistry, Population, Nonsense mutation, Lipoxygenase, Mutagenesis (molecular biology technique), SNP, Single-nucleotide polymorphism, Biology, Biochemistry, Polymorphism, Single Nucleotide, LTA4, 4-[(2S,3S)-3-[(1E,3E,5Z,8Z)-tetradeca-1,3,5,8-tetraen-1-yl]oxiran-2-yl]butanoic acid, Article, H(p)ETE, hydroperoxyeicosatetraenoic acid, LOXs, lipoxygenases, 15-H(p)ETE, (5Z,8Z,11Z,13E)-15-hydroperoxyeicosa-5,8,11,13-tetraenoic acid, Evolution, Molecular, Mutation Rate, HETE, hydroxyeicosatetraenoic acid, Genetic variation, Humans, LTC4, (5S,6R,7E,9E,11Z,14Z)-6-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl) carbamoyl]ethyl]sulfanyl}-5-hydroxyeicosa-7,9,11,14-tetraenoic acid, 1000 Genomes Project, education, lcsh:QH301-705.5, Gene, IPTG, Isopropyl-β-D-thiogalactopyranosid, Genetics, lcsh:R5-920, education.field_of_study, Organic Chemistry, Gene polymorphism, Genetic Variation, 5-H(p)ETE, (6E,8Z,11Z,14Z)-5-hydroperoxyeicosa-6,8,11,14-tetraenoic acid, 12-H(p)ETE, (5Z,8Z,10E,14Z)-12-hydroperoxyeicosa-5,8,10,14-tetraenoic acid, 8-H(p)ETE, (5Z,9E,11Z,14Z)-8-hydroperoxyeicosa-5,9,11,14-tetraenoic acid, Lipoxygenases, ALOX, arachidonate lipoxygenase, UTR, untranslated region, lcsh:Biology (General), ALOX12, Codon, Nonsense, LTB4, 5(S),12(R)-dihydroxy-6,8,10,14-(Z,E,E,Z)-eicosatetraenoic acid, Eicosanoids, lcsh:Medicine (General)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc39c4a48e2da0075fb4ffe924a8d4b3
https://pubmed.ncbi.nlm.nih.gov/24282679

المؤلفون: Aparoy, Polamarasetty, Kumar Reddy, Kakularam, Reddanna, Pallu

المصدر: Current Medicinal Chemistry ; volume 19, issue 22, page 3763-3778 ; ISSN 0929-8673

الاتاحة: http://dx.doi.org/10.2174/092986712801661112
http://eurekaselect.com/article/download/100314

المؤلفون: Hartmut Kühn, Almerinda Di Venere, Melanie L. Conrad, Kumar Reddy Kakularam, Patrick Scheerer, Constanze Richter, Thomas Horn, Pallu Reddanna, Igor Ivanov

المصدر: Biochimica et biophysica acta. 1831(12)

مصطلحات موضوعية: Models, Molecular, Protein Folding, Glutamine, Mutant, Molecular Sequence Data, Glycine, Biology, medicine.disease_cause, Isozyme, Conserved sequence, Catalytic Domain, Enzyme Stability, Hydroxyeicosatetraenoic Acids, medicine, Escherichia coli, Animals, Arachidonate 15-Lipoxygenase, Humans, Amino Acid Sequence, Settore BIO/10, Molecular Biology, Gene, Conserved Sequence, chemistry.chemical_classification, Mutation, Sequence Homology, Amino Acid, Cell Biology, Recombinant Proteins, Isoenzymes, Kinetics, Enzyme, Biochemistry, chemistry, ALOX12, Thermodynamics, Protein folding, Rabbits

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb93635fe690c1aff7904c7d5975479
https://pubmed.ncbi.nlm.nih.gov/23958500