المؤلفون: Sophia L. Samodelov, Zhibo Gai, Francesca De Luca, Klara Haldimann, Sven N. Hobbie, Daniel Müller, Gerd A. Kullak-Ublick, Michele Visentin

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Colistin, Drug-induced kidney injury, Kim-1, L-carnitine, Mitochondria, Nephrotoxicity polymyxins, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a51caf5e8b014775b1788ea24ca7f003

المؤلفون: Bostrom, AE, Chatzittofis, A, Ciuculete, DM, Flanagan, JN, Krattinger, R, Bandstein, M, Mwinyi, J, Kullak-Ublick, GA, Oberg, KG, Arver, S, Schioth, HB, Jokinen, J

المصدر: Epigenetics. 15(1-2):145-160

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:142081477

المؤلفون: Akhmedov, A, Bonetti, NR, Reiner, MF, Spescha, RD, Amstalden, H, Merlini, M, Gaul, DS, Diaz-Canestro, C, Briand-Schumacher, S, Spescha, RS, Semerano, A, Giacalone, G, Savarese, G, Montecucco, F, Kulic, L, Nitsch, RM, Matter, CM, Kullak-Ublick, GA, Sessa, M, Luescher, TF, Beer, JH, Liberale, L, Camici, GG

المصدر: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 39(11):2233-2245

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:142434928

المؤلفون: Church, RJ, Kullak-Ublick, GA, Aubrecht, J, Bonkovsky, HL, Chalasani, N, Fontana, RJ, Goepfert, JC, Hackman, F, King, NMP, Kirby, S, Kirby, P, Marcinak, J, Ormarsdottir, S, Schomaker, SJ, Schuppe-Koistinen, I, Wolenski, F, Arber, N, Merz, M, Sauer, JM, Andrade, RJ, van Bommel, F, Poynard, T, Watkins, PB

المصدر: Hepatology (Baltimore, Md.). 69(2):760-773

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:140189261

المؤلفون: Andreas Trojan, Emanuele Laurenzi, Stephan Jüngling, Sven Roth, Michael Kiessling, Ziad Atassi, Yannick Kadvany, Meinrad Mannhart, Christian Jackisch, Gerd Kullak-Ublick, Hans Friedrich Witschel

المصدر: Frontiers in Digital Health, Vol 6 (2024)

مصطلحات موضوعية: cancer, ePROs, systemic therapy, digital patient monitoring, interactive machine learning, early warning systems (EWS), Medicine, Public aspects of medicine, RA1-1270, Electronic computers. Computer science, QA75.5-76.95

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fdgth.2024.1443987/full; https://doaj.org/toc/2673-253X

URL الوصول: https://doaj.org/article/b73687fc63bc423ea85ada7bc1ad7170

المؤلفون: Seth Duwor, Katharina Enthofer, Christoph Ganter, Prabin Poudel, Anna Svarin, Gerd A. Kullak-Ublick

المصدر: Pharmacoepidemiology, Vol 3, Iss 1, Pp 33-50 (2024)

مصطلحات موضوعية: calcineurin inhibitors, cytochrome P450, therapeutic drug monitoring, intoxication, pharmacovigilance, pharmacoenhancement, Therapeutics. Pharmacology, RM1-950, Other systems of medicine, RZ201-999, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2813-0618/3/1/2; https://doaj.org/toc/2813-0618

URL الوصول: https://doaj.org/article/cff3d84d5787481db17d8967cc6c97e9

المؤلفون: Jane I. Grove, Camilla Stephens, M. Isabel Lucena, Raúl J. Andrade, Sabine Weber, Alexander Gerbes, Einar S. Bjornsson, Guido Stirnimann, Ann K. Daly, Matthias Hackl, Kseniya Khamina-Kotisch, Jose J. G. Marin, Maria J. Monte, Sara A. Paciga, Melanie Lingaya, Shiva S. Forootan, Christopher E. P. Goldring, Oliver Poetz, Rudolf Lombaard, Alexandra Stege, Helgi K. Bjorrnsson, Mercedes Robles-Diaz, Dingzhou Li, Thi Dong Binh Tran, Shashi K. Ramaiah, Sophia L. Samodelov, Gerd A. Kullak-Ublick, Guruprasad P. Aithal, on behalf of the TransBioLine consortium

المصدر: Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2397-7523

URL الوصول: https://doaj.org/article/01c9031ea63844faa64609c76d355eda

المؤلفون: Andreas Trojan, Christian Kühne, Michael Kiessling, Johannes Schumacher, Stefan Dröse, Christian Singer, Christian Jackisch, Christoph Thomssen, Gerd A Kullak-Ublick

المصدر: JMIR Formative Research, Vol 8, p e55917 (2024)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://formative.jmir.org/2024/1/e55917; https://doaj.org/toc/2561-326X

URL الوصول: https://doaj.org/article/869aa6dfcdec43b9ab44d038d3dac136

المؤلفون: Andreas Trojan, Sven Roth, Ziad Atassi, Michael Kiessling, Reinhard Zenhaeusern, Yannick Kadvany, Johannes Schumacher, Gerd A Kullak-Ublick, Matti Aapro, Alexandru Eniu

المصدر: JMIR Cancer, Vol 10, p e54178 (2024)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://cancer.jmir.org/2024/1/e54178; https://doaj.org/toc/2369-1999

URL الوصول: https://doaj.org/article/93eadb61cfc44112ad034c037c1f76ca

المؤلفون: M.I. Lucena, M. Villanueva-Paz, I. Alvarez-Alvarez, G.P. Aithal, E.S. Björnsson, G. Cakan-Akdogan, F.J. Cubero, F. Esteves, J.M. Falcon-Perez, B. Fromenty, C. Garcia-Ruiz, J.I. Grove, O. Konu, M. Kranendonk, G.A. Kullak-Ublick, J.P. Miranda, A. Remesal-Doblado, P. Sancho-Bru, L. Nelson, R.J. Andrade, A.K. Daly, J.C. Fernandez-Checa

المصدر: Pharmacological Research, Vol 200, Iss , Pp 107046- (2024)

مصطلحات موضوعية: Idiosyncratic Drug-induced liver injury, Preclinical models, Integrative database, DILI prediction, Humanized Mouse Models, Organ-on-a-chip, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661823004024; https://doaj.org/toc/1096-1186

URL الوصول: https://doaj.org/article/2c7c8e11fae04b7f942b7aa0a4dabc81

المؤلفون: Lucena MI, Villanueva-Paz M, Alvarez-Alvarez I, Aithal GP, Bjornsson ES, Cakan-Akdogan G, Cubero FJ, Esteves F, Falcon-Perez JM, Fromenty B, Garcia-Ruiz C, Grove JI, Konu O, Kranendonk M, Kullak-Ublick GA, Miranda JP, Remesal-Doblado A, Sancho-Bru P, Nelson L, Andrade RJ, Daly AK, Fernandez-Checa JC

المصدر: Pharmacological Research, February 2024

وصف الملف: application/pdf

Relation: https://eprints.ncl.ac.uk/296161; https://eprints.ncl.ac.uk/fulltext.aspx?url=296161/06061DF0-61F0-4B92-A7D3-A84948988E31.pdf&pub_id=296161

الاتاحة: https://eprints.ncl.ac.uk/296161

المؤلفون: Giovannoni, Luis, Kullak-Ublick, Gerd A, Jetter, Alexander

المصدر: Giovannoni, Luis; Kullak-Ublick, Gerd A; Jetter, Alexander (2024). Developing a Model for Quantifying QTc-Prolongation Risk to Enhance Medication Safety Assessment: A Retrospective Analysis. Journal of Personalized Medicine, 14(2):172.

مصطلحات موضوعية: Clinic for Clinical Pharmacology and Toxicology, 610 Medicine & health, QTc prolongation, QT-prolonging drugs, medication safety assessment

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/257669/1/ZORA_pdf_version_1706758124.pdf; info:pmid/38392605; urn:issn:2075-4426

الاتاحة: https://www.zora.uzh.ch/id/eprint/257669/
https://www.zora.uzh.ch/id/eprint/257669/1/ZORA_pdf_version_1706758124.pdf
https://doi.org/10.3390/jpm14020172

المؤلفون: Thomson, Paul, Fragkas, Nik, Kafu, Laila M, Aithal, Guruprasad P, Lucena, M Isabel, Terracciano, Luigi, Meng, Xiaoli, Pirmohamed, Munir, Brees, Dominique, Kullak‐Ublick, Gerd A, Odermatt, Alex, Hammond, Thomas, Kammüller, Michael, Naisbitt, Dean J

المصدر: Thomson, Paul; Fragkas, Nik; Kafu, Laila M; Aithal, Guruprasad P; Lucena, M Isabel; Terracciano, Luigi; Meng, Xiaoli; Pirmohamed, Munir; Brees, Dominique; Kullak‐Ublick, Gerd A; Odermatt, Alex; Hammond, Thomas; Kammüller, Michael; Naisbitt, Dean J (2024). Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-Desmethyl Naproxen metabolite but not the acyl glucuronide. Allergy, 79(1):200-214.

مصطلحات موضوعية: Clinic for Clinical Pharmacology and Toxicology, 610 Medicine & health, Immunology, Immunology and Allergy

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/237585/1/ZORA_Allergy_20__202023_20__20Thomson.pdf; info:pmid/37515456; urn:issn:0105-4538

الاتاحة: https://www.zora.uzh.ch/id/eprint/237585/
https://www.zora.uzh.ch/id/eprint/237585/1/ZORA_Allergy_20__202023_20__20Thomson.pdf
https://doi.org/10.1111/all.15830

المؤلفون: Samodelov, Sophia L, Gai, Zhibo, De Luca, Francesca, Haldimann, Klara, Hobbie, Sven N, Müller, Daniel, Kullak-Ublick, Gerd A, Visentin, Michele

المصدر: Samodelov, Sophia L; Gai, Zhibo; De Luca, Francesca; Haldimann, Klara; Hobbie, Sven N; Müller, Daniel; Kullak-Ublick, Gerd A; Visentin, Michele (2024). L-carnitine co-administration prevents colistin-induced mitochondrial permeability transition and reduces the risk of acute kidney injury in mice. Scientific Reports, 14(1):16444.

مصطلحات موضوعية: Clinic for Clinical Pharmacology and Toxicology, 610 Medicine & health, Colistin, Drug-induced kidney injury, Kim-1, L-carnitine, Mitochondria, Nephrotoxicity polymyxins, Proximal tubule

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/261599/1/ZORA_261599.pdf; info:pmid/39013979; urn:issn:2045-2322

الاتاحة: https://www.zora.uzh.ch/id/eprint/261599/
https://www.zora.uzh.ch/id/eprint/261599/1/ZORA_261599.pdf

المؤلفون: Kastrinou-Lampou, Vlasia, Rodríguez-Pérez, Raquel, Poller, Birk, Huth, Felix, Schadt, Heiko S, Kullak-Ublick, Gerd A, Arand, Michael, Camenisch, Gian

المصدر: Kastrinou-Lampou, Vlasia; Rodríguez-Pérez, Raquel; Poller, Birk; Huth, Felix; Schadt, Heiko S; Kullak-Ublick, Gerd A; Arand, Michael; Camenisch, Gian (2025). Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms. Archives of Toxicology, 99(1):377-391.

مصطلحات موضوعية: Institute of Pharmacology and Toxicology, Clinic for Clinical Pharmacology and Toxicology, 570 Life sciences, biology, 610 Medicine & health

Time: 142-005

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/265399/1/Drug_induced_cholestasis.pdf; info:pmid/39542928; urn:issn:0340-5761

الاتاحة: https://www.zora.uzh.ch/id/eprint/265399/
https://www.zora.uzh.ch/id/eprint/265399/1/Drug_induced_cholestasis.pdf

المؤلفون: Andrade, Raúl J, Aithal, Guruprasad P, de Boer, Ynto S, Liberal, Rodrigo, Gerbes, Alexander, Regev, Arie, Terziroli Beretta-Piccoli, Benedetta, Schramm, Christoph, Kleiner, David E, De Martin, Eleonora, Kullak-Ublick, Gerd A, Stirnimann, Guido, Devarbhavi, Harshad, Vierling, John M, Manns, Michael P, Sebode, Marcial, Londoño, Maria Carlota, Avigan, Mark, Robles-Diaz, Mercedes, García-Cortes, Miren, Atallah, Edmond, Heneghan, Michael, Chalasani, Naga, Trivedi, Palak J, Hayashi, Paul H, Taubert, Richard, Fontana, Robert J, Weber, Sabine, Oo, Ye Htun, Zen, Yoh, Licata, Anna, Lucena, M Isabel, Mieli-Vergani, Giorgina, Vergani, Diego, Björnsson, Einar S

المساهمون: Andrade, Raúl J, Aithal, Guruprasad P, de Boer, Ynto S, Liberal, Rodrigo, Gerbes, Alexander, Regev, Arie, Terziroli Beretta-Piccoli, Benedetta, Schramm, Christoph, Kleiner, David E, De Martin, Eleonora, Kullak-Ublick, Gerd A, Stirnimann, Guido, Devarbhavi, Harshad, Vierling, John M, Manns, Michael P, Sebode, Marcial, Londoño, Maria Carlota, Avigan, Mark, Robles-Diaz, Mercede, García-Cortes, Miren, Atallah, Edmond, Heneghan, Michael, Chalasani, Naga, Trivedi, Palak J, Hayashi, Paul H, Taubert, Richard, Fontana, Robert J, Weber, Sabine, Oo, Ye Htun, Zen, Yoh, Licata, Anna, Lucena, M Isabel, Mieli-Vergani, Giorgina, Vergani, Diego, Björnsson, Einar S

مصطلحات موضوعية: AIH, DI-ALH, DILI, Drug-induced autoimmune-like hepatitis, Liver injury, autoimmune hepatitis, diagnosis, drug-induced liver injury, epidemiology, hepatotoxicity, management, outcome

Relation: info:eu-repo/semantics/altIdentifier/pmid/37164270; info:eu-repo/semantics/altIdentifier/wos/WOS:001065088800001; volume:79; issue:3; firstpage:853; lastpage:866; numberofpages:14; journal:JOURNAL OF HEPATOLOGY; https://hdl.handle.net/10447/619501

الاتاحة: https://hdl.handle.net/10447/619501
https://doi.org/10.1016/j.jhep.2023.04.033

المؤلفون: Max Maane, Fangrui Xiu, Peter Bellstedt, Gerd A. Kullak-Ublick, Michele Visentin

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: cis-inhibition, OCT, organic cation transporter, SLC, thermal shift assay, thermodynamic stabilization, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1154213/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/70468cc9ab774e55a56d25d254b6394e

المؤلفون: Ting Gui, Qingfa Chen, Jiangsong Li, Ke Lu, Chen Li, Bin Xu, Yang Chen, Jingwen Men, Gerd A. Kullak-Ublick, Weihua Wang, Zhibo Gai

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: chronic kidney disease, 1-deoxysphingolipids, mitochondrial dysfunction, astragaloside IV, nuclear factor erythroid-related factor 2, p62, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1092475/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/7e9c1537b3804c118fb2b076e867cfd3

المؤلفون: Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P. Grobusch, Etienne Karita, Henry Mugerwa, Stephen Asiimwe, Abraham Oduro, Bakary Fofana, Seydou Doumbia, Jay Prakash Jain, Sarita Barsainya, Gerd A. Kullak-Ublick, Guoqin Su, Esther K. Schmitt, Katalin Csermak, Preetam Gandhi, David Hughes

المصدر: Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Cipargamin, Malaria, KAE609, Hepatic safety, Phase II randomized controlled trial, Plasmodium falciparum, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/890ef9801b434e61bb32253a0c40d2ec

المؤلفون: Grove, Jane I, Stephens, Camilla, Lucena, M Isabel, Andrade, Raúl J, Weber, Sabine, Gerbes, Alexander, Bjornsson, Einar S, Stirnimann, Guido, Daly, Ann K, Hackl, Matthias, Khamina-Kotisch, Kseniya, Marin, Jose J G, Monte, Maria J, Paciga, Sara A, Lingaya, Melanie, Forootan, Shiva S, Goldring, Christopher E P, Poetz, Oliver, Lombaard, Rudolf, Stege, Alexandra, Bjorrnsson, Helgi K, Robles-Diaz, Mercedes, Li, Dingzhou, Tran, Thi Dong Binh, Ramaiah, Shashi K, Samodelov, Sophia L, Kullak-Ublick, Gerd A, Aithal, Guruprasad P

المصدر: Grove, Jane I; Stephens, Camilla; Lucena, M Isabel; Andrade, Raúl J; Weber, Sabine; Gerbes, Alexander; Bjornsson, Einar S; Stirnimann, Guido; Daly, Ann K; Hackl, Matthias; Khamina-Kotisch, Kseniya; Marin, Jose J G; Monte, Maria J; Paciga, Sara A; Lingaya, Melanie; Forootan, Shiva S; Goldring, Christopher E P; Poetz, Oliver; Lombaard, Rudolf; Stege, Alexandra; Bjorrnsson, Helgi K; Robles-Diaz, Mercedes; Li, Dingzhou; Tran, Thi Dong Binh; Ramaiah, Shashi K; Samodelov, Sophia L; Kullak-Ublick, Gerd A; Aithal, Guruprasad P (2023). Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol ....

مصطلحات موضوعية: Clinic for Clinical Pharmacology and Toxicology, 610 Medicine & health, Religious studies, Cultural Studies

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/237586/1/s41512_023_00155_z.pdf; info:pmid/37697410; urn:issn:2397-7523

الاتاحة: https://www.zora.uzh.ch/id/eprint/237586/
https://www.zora.uzh.ch/id/eprint/237586/1/s41512_023_00155_z.pdf