المؤلفون: Roy, Suchismita, Sinha, Saptarshi, Silas, Ananta James, Ghassemian, Majid, Kufareva, Irina, Ghosh, Pradipta

المصدر: Science Signaling. 17(839)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Generic health relevance, Phosphorylation, Signal Transduction, Humans, HEK293 Cells, GTP-Binding Protein alpha Subunits, Gi-Go, Receptors, CXCR4, Epidermal Growth Factor, Receptors, G-Protein-Coupled, Animals, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/11p4w9fm
https://escholarship.org/content/qt11p4w9fm/qt11p4w9fm.pdf

المؤلفون: Wedegaertner, Helen, Bosompra, Oye, Kufareva, Irina, Trejo, JoAnn

المصدر: Molecular Biology of the Cell. 34(9)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Breast Cancer, Women's Health, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Neurological, Arrestin, Ubiquitination, Nedd4 Ubiquitin Protein Ligases, Arrestins, Signal Transduction, Ubiquitin-Protein Ligases, Medical and Health Sciences, Developmental Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5528664r
https://escholarship.org/content/qt5528664r/qt5528664r.pdf

المؤلفون: Shroka, Thomas M, Kufareva, Irina, Salanga, Catherina L, Handel, Tracy M

المصدر: Science Signaling. 16(770)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Mice, Animals, Receptors, Chemokine, Mice, Knockout, Chemokines, Chemokine CCL2, beta-Arrestins, Receptors, CCR2, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7tg829jd
https://escholarship.org/content/qt7tg829jd/qt7tg829jd.pdf

المؤلفون: Carretero Chavez, Willow, Krantz, Marcus, Klipp, Edda, Kufareva, Irina

المصدر: BMC Bioinformatics. 24(1)

مصطلحات موضوعية: Bioengineering, Networking and Information Technology R&D (NITRD), Databases, Factual, Documentation, Kinetics, Signal Transduction, Software, Computational modeling, Cell signaling, Network biology, Rxncon, Boolean networks, Mathematical Sciences, Biological Sciences, Information and Computing Sciences, Bioinformatics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/47s8w0pm
https://escholarship.org/content/qt47s8w0pm/qt47s8w0pm.pdf

المؤلفون: Navia-Pelaez, Juliana M, Choi, Soo-Ho, dos Santos Aggum Capettini, Luciano, Xia, Yining, Gonen, Ayelet, Agatisa-Boyle, Colin, Delay, Lauriane, dos Santos, Gilson Gonçalves, Catroli, Glaucilene F, Kim, Jungsu, Lu, Jenny W, Saylor, Benjamin, Winkels, Holger, Durant, Christopher P, Ghosheh, Yanal, Beaton, Graham, Ley, Klaus, Kufareva, Irina, Corr, Maripat, Yaksh, Tony L, Miller, Yury I

المصدر: Journal of Experimental Medicine. 218(7)

مصطلحات موضوعية: Pain Research, Neurodegenerative, Neurosciences, Peripheral Neuropathy, Genetics, Chronic Pain, Aetiology, 2.1 Biological and endogenous factors, Neurological, ATP Binding Cassette Transporter 1, ATP Binding Cassette Transporter, Subfamily G, Member 1, Animals, Biological Transport, Cell Line, Cholesterol, HEK293 Cells, Humans, Inflammation, Male, Membrane Microdomains, Mice, Mice, Inbred C57BL, Microglia, Neuralgia, Protein Binding, Signal Transduction, Spinal Cord, Medical and Health Sciences, Immunology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3342r38r

المؤلفون: Zacarías, Natalia V Ortiz, Chahal, Kirti K, Šimková, Tereza, van der Horst, Cas, Zheng, Yi, Inoue, Asuka, Theunissen, Emy, Mallee, Lloyd, van der Es, Daan, Louvel, Julien, IJzerman, Adriaan P, Handel, Tracy M, Kufareva, Irina, Heitman, Laura H

المصدر: Journal of Medicinal Chemistry. 64(5)

مصطلحات موضوعية: Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Binding Sites, CHO Cells, Cell Line, Tumor, Cricetulus, Cysteine, Drug Design, HEK293 Cells, Humans, Ligands, Molecular Docking Simulation, Mutagenesis, Site-Directed, Mutation, Protein Binding, Receptors, CCR2, Sulfonamides, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/32q1j7bs

المؤلفون: Ear, Jason, El-Hafeez, Amer Ali Abd, Roy, Suchismita, Ngo, Tony, Rajapakse, Navin, Choi, Julie, Khandelwal, Soni, Ghassemian, Majid, McCaffrey, Luke, Kufareva, Irina, Sahoo, Debashis, Ghosh, Pradipta

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Genetics, 1.1 Normal biological development and functioning, 5.1 Pharmaceuticals, Generic health relevance, Animals, Cell Line, Cell Line, Tumor, Cell Proliferation, Colonic Neoplasms, GTP-Binding Protein alpha Subunits, Gi-Go, Guanine Nucleotide Exchange Factors, Humans, Microfilament Proteins, PDZ Domains, Phosphorylation, Protein Binding, Protein Isoforms, Protein Transport, Signal Transduction, Vesicular Transport Proteins, Zebrafish, cancer, cell biology, cell junctions, cell signaling, protein interactions, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/03d8f26n
https://escholarship.org/content/qt03d8f26n/qt03d8f26n.pdf

المؤلفون: Kalogriopoulos, Nicholas A, Lopez-Sanchez, Inmaculada, Lin, Changsheng, Ngo, Tony, Midde, Krishna K, Roy, Suchismita, Aznar, Nicolas, Murray, Fiona, Garcia-Marcos, Mikel, Kufareva, Irina, Ghassemian, Majid, Ghosh, Pradipta

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(46)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, 1.1 Normal biological development and functioning, Animals, COS Cells, Chlorocebus aethiops, ErbB Receptors, GTP-Binding Protein alpha Subunits, HEK293 Cells, HeLa Cells, Heterotrimeric GTP-Binding Proteins, Humans, Phosphorylation, Receptor Protein-Tyrosine Kinases, Signal Transduction, Tyrosine, heterotrimeric G proteins, growth factor receptor tyrosine kinases, EGFR, tyrosine phosphorylation, transactivation, Hela Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/18z0c8nf
https://escholarship.org/content/qt18z0c8nf/qt18z0c8nf.pdf

المؤلفون: Swanson, Lee, Katkar, Gajanan D, Tam, Julian, Pranadinata, Rama F, Chareddy, Yogitha, Coates, Jane, Anandachar, Mahitha Shree, Castillo, Vanessa, Olson, Joshua, Nizet, Victor, Kufareva, Irina, Das, Soumita, Ghosh, Pradipta

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(43)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Infectious Diseases, 2.1 Biological and endogenous factors, Inflammatory and immune system, Animals, Colitis, Disease Models, Animal, Female, HEK293 Cells, Humans, Macrophages, Mice, Mice, Knockout, Microfilament Proteins, RAW 264.7 Cells, Sepsis, Signal Transduction, Toll-Like Receptor 4, Vesicular Transport Proteins, Girdin, TIR domain, inflammation, macrophages, ccdc88a

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/09v968vw
https://escholarship.org/content/qt09v968vw/qt09v968vw.pdf

المؤلفون: Stephens, Bryan S, Ngo, Tony, Kufareva, Irina, Handel, Tracy M

المصدر: Science Signaling. 13(640)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 2.1 Biological and endogenous factors, Cancer, Generic health relevance, Animals, CHO Cells, Chemokine CXCL12, Cricetulus, HEK293 Cells, Humans, Models, Molecular, Multiprotein Complexes, Mutagenesis, Site-Directed, Protein Structure, Quaternary, Receptors, CXCR4, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/31d6j6np
https://escholarship.org/content/qt31d6j6np/qt31d6j6np.pdf

المؤلفون: Jaracz‐Ros, Agnieszka, Bernadat, Guillaume, Cutolo, Pasquale, Gallego, Carmen, Gustavsson, Martin, Cecon, Erika, Baleux, Françoise, Kufareva, Irina, Handel, Tracy M, Bachelerie, Françoise, Levoye, Angélique

المصدر: Journal of Leukocyte Biology. 107(6)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Emerging Infectious Diseases, Biotechnology, Prevention, Vaccine Related, Biodefense, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Amino Acid Sequence, Benzylamines, Binding Sites, Chemokine CXCL11, Chemokine CXCL12, Cyclams, Cyclic AMP, Gene Expression, HEK293 Cells, Heterocyclic Compounds, Humans, Molecular Dynamics Simulation, Mutation, Oligopeptides, Protein Binding, Protein Conformation, alpha-Helical, Protein Conformation, beta-Strand, Protein Interaction Domains and Motifs, Receptors, CXCR, Receptors, CXCR4, Recombinant Proteins, beta-Arrestins, ACKR3, chemokine variants, CXCL12, CXCR4, GPCR signaling, pluridimensional efficacy, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5hd7z1fw

المؤلفون: Ngo, Tony, Stephens, Bryan S, Gustavsson, Martin, Holden, Lauren G, Abagyan, Ruben, Handel, Tracy M, Kufareva, Irina

المصدر: PLoS biology. 18(4)

مصطلحات موضوعية: Animals, Humans, Disulfides, Cysteine, Receptors, CXCR4, Blotting, Western, Flow Cytometry, Binding Sites, Protein Conformation, Mutation, Models, Molecular, Chemokine CXCL12, Protein Interaction Domains and Motifs, HEK293 Cells, beta-Arrestins, Insecta, Receptors, CXCR4, Blotting, Western, Models, Molecular, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/68f331zf

المؤلفون: Josephs, Tracy M, Keller, Andrew N, Khajehali, Elham, DeBono, Aaron, Langmead, Christopher J, Conigrave, Arthur D, Capuano, Ben, Kufareva, Irina, Gregory, Karen J, Leach, Katie

المصدر: British Journal of Pharmacology. 177(8)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Underpinning research, 1.1 Normal biological development and functioning, Allosteric Regulation, Allosteric Site, Binding Sites, HEK293 Cells, Humans, Receptors, Calcium-Sensing, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9kc638dm

المؤلفون: Nicola, George, Kufareva, Irina, Ilatovskiy, Andrey V, Abagyan, Ruben

المصدر: Journal of Computer-Aided Molecular Design. 34(3)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Biotechnology, 5.1 Pharmaceuticals, Generic health relevance, Adenosine Triphosphate, Binding Sites, Drug Design, Genome, Human, Humans, Protein Binding, Protein Domains, Protein Kinases, Surface Properties, Kinase, Kinome, Pocket, Pocketome, Exosite, Exositome, Drugable, Druggable, Bioinformatics, Cheminformatics, Drug discovery, Protein, Target, Theoretical and Computational Chemistry, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Theoretical and computational chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3q47r7h8
https://escholarship.org/content/qt3q47r7h8/qt3q47r7h8.pdf

المؤلفون: Ear, Jason, Saklecha, Anokhi, Rajapakse, Navin, Choi, Julie, Ghassemian, Majid, Kufareva, Irina, Ghosh, Pradipta

المصدر: iScience. 23(2)

مصطلحات موضوعية: Biological Sciences, Cell Biology, Functional Aspects of Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4sc493j6

المؤلفون: Zhao, Bin N, Campbell, James J, Salanga, Catherina L, Ertl, Linda S, Wang, Yu, Yau, Simon, Dang, Ton, Zeng, Yibin, McMahon, Jeffrey P, Krasinski, Antoni, Zhang, Penglie, Kufareva, Irina, Handel, Tracy M, Charo, Israel F, Singh, Rajinder, Schall, Thomas J

المصدر: The Journal of Immunology. 203(12)

مصطلحات موضوعية: Underpinning research, 1.1 Normal biological development and functioning, Animals, Biomarkers, Cell Line, Chemokine CCL2, Dose-Response Relationship, Drug, Female, Gene Expression, Humans, Mice, Monocytes, Receptors, CCR2, Immunology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9sc9p452

المؤلفون: Kufareva, Irina, Bestgen, Benoit, Brear, Paul, Prudent, Renaud, Laudet, Béatrice, Moucadel, Virginie, Ettaoussi, Mohamed, Sautel, Celine F, Krimm, Isabelle, Engel, Matthias, Filhol, Odile, Borgne, Marc Le, Lomberget, Thierry, Cochet, Claude, Abagyan, Ruben

المصدر: Scientific reports. 9(1)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/05r8j6xs

المؤلفون: Kalogriopoulos, Nicholas A, Rees, Steven D, Ngo, Tony, Kopcho, Noah J, Ilatovskiy, Andrey V, Sun, Nina, Komives, Elizabeth A, Chang, Geoffrey, Ghosh, Pradipta, Kufareva, Irina

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(33)

مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Generic health relevance, Allosteric Regulation, Crystallography, X-Ray, GTP-Binding Protein alpha Subunits, Gi-Go, Guanine Nucleotide Exchange Factors, HeLa Cells, Heterotrimeric GTP-Binding Proteins, Humans, Hydrophobic and Hydrophilic Interactions, Microfilament Proteins, Molecular Dynamics Simulation, Protein Binding, Protein Conformation, Receptors, G-Protein-Coupled, Signal Transduction, Vesicular Transport Proteins, guanine-nucleotide exchange modulator, GIV/Girdin, X-ray crystallography, hydrogen-deuterium exchange, molecular dynamics, Hela Cells, hydrogen–deuterium exchange

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8cb3p6mr
https://escholarship.org/content/qt8cb3p6mr/qt8cb3p6mr.pdf

المؤلفون: Regan, Daniel P, Coy, Jonathan W, Chahal, Kirti Kandhwal, Chow, Lyndah, Kurihara, Jade N, Guth, Amanda M, Kufareva, Irina, Dow, Steven W

المصدر: The Journal of Immunology. 202(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Rare Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Aetiology, 2.1 Biological and endogenous factors, Angiotensin II Type 1 Receptor Blockers, Animals, Cell Line, Tumor, Female, Humans, Losartan, Lung Neoplasms, MAP Kinase Signaling System, Mice, Mice, Inbred BALB C, Mice, Inbred ICR, Mice, Knockout, Monocytes, Neoplasm Metastasis, Neoplasm Proteins, Neoplasms, Experimental, Receptor, Angiotensin, Type 1, Receptors, CCR2, Immunology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2qj1v37r

المؤلفون: Bestgen, Benoît, Kufareva, Irina, Seetoh, Weiguang, Abell, Chris, Hartmann, Rolf W, Abagyan, Ruben, Le Borgne, Marc, Filhol, Odile, Cochet, Claude, Lomberget, Thierry, Engel, Matthias

المصدر: Journal of Medicinal Chemistry. 62(4)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Cancer, 5.1 Pharmaceuticals, Allosteric Regulation, Allosteric Site, Antineoplastic Agents, Apoptosis, Benzoates, Casein Kinase II, Cell Line, Tumor, Humans, Ligands, Molecular Docking Simulation, Molecular Structure, Naphthyridines, Phenazines, Prodrugs, Protein Binding, Protein Kinase Inhibitors, Structure-Activity Relationship, Thiazoles, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3rz1t4h5
https://escholarship.org/content/qt3rz1t4h5/qt3rz1t4h5.pdf