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1
المؤلفون: Kristoffer W. Balling, Brian Lauritzen, Janne Olling, Mads Bjelke, Cecilia Augustsson, Ida Hilden, Anne Charlotte Hegelund, Kristin L. Abel
المصدر: Journal of thrombosis and haemostasis : JTH. 17(3)
مصطلحات موضوعية: Hemorrhage, Factor VIIa, 030204 cardiovascular system & hematology, Pharmacology, Antibodies, Monoclonal, Humanized, Hemophilia A, Hemostatics, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tissue factor pathway inhibitor, In vivo, Breakthrough bleeding, Medicine, Potency, Animals, Humans, Drug Interactions, Hemostasis, biology, Factor VII, medicine.diagnostic_test, business.industry, Hematology, Thromboelastography, Toxicokinetics, Disease Models, Animal, Macaca fascicularis, Coagulation, chemistry, Recombinant factor VIIa, biology.protein, Female, Rabbits, medicine.symptom, business
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2
المؤلفون: Berit Olsen Krogh, Brit B. Sørensen, L. Anders Svensson, Mirella Ezban, Kristoffer W. Balling, Jens Breinholt, Helle Heibroch Petersen, Jes Thorn Clausen, Lene Hansen, Christina Jespersgaard, Birgitte Friederichsen, Albrecht Gruhler, Andrew Neil Bowler, Brian Lauritzen, Lars Christian Petersen, Søren E. Bjørn, Thomas Egebjerg, Mette B. Hermit, Ida Hilden
المصدر: Blood. 119:5871-5878
مصطلحات موضوعية: Models, Molecular, Bleeding Time, medicine.drug_class, Lipoproteins, Immunology, Cross Reactions, Pharmacology, Antibodies, Monoclonal, Humanized, Hemophilia A, Monoclonal antibody, Biochemistry, Thromboplastin, Epitopes, Tissue factor, Tissue factor pathway inhibitor, Species Specificity, Neutralization Tests, Bleeding time, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Antibodies, Blocking, Blood Coagulation, Factor IX, Fibrin, Hemostasis, Factor VIII, medicine.diagnostic_test, biology, business.industry, Cell Biology, Hematology, Antibodies, Neutralizing, Protein Structure, Tertiary, Disease Models, Animal, HEK293 Cells, Coagulation, Factor Xa, Monoclonal, biology.protein, Female, Rabbits, Antibody, business, Protein Binding, medicine.drug
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3
المؤلفون: Mirella Ezban, S. Segel, Thomas Dock Steenstrup, A. Bagger-Sørensen, Egon Persson, Stefan Lethagen, Niels Kristian Klausen, Ida Hilden, M. L. S. Christiansen, Dorthe Viuff, Brit B. Sørensen, Kristoffer W. Balling, Marianne Kjalke
المصدر: Haemophilia. 16:878-887
مصطلحات موضوعية: biology, medicine.diagnostic_test, business.industry, Factor X, Haemophilia A, Hematology, General Medicine, Turoctocog alfa, medicine.disease, Molecular biology, Thromboelastography, law.invention, chemistry.chemical_compound, Thrombin, Von Willebrand factor, chemistry, law, Immunology, biology.protein, medicine, Recombinant DNA, business, Genetics (clinical), Protein C, medicine.drug
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4
المؤلفون: Christina Jespersgaard, Flemming Möller, Torben Elm, Wendy Kappers, Mikael Tranholm, Bernd Peschke, Henning R. Stennicke, Hermann Pelzer, Ditte M. Karpf, Anne K. Kristensen, Ida Hilden, Mirella Ezban, Are Bogsnes, Heidi L. Holmberg, Egon Persson, Anette A. Pedersen, Peter B. Johansen, Henrik Rahbek-Nielsen, Lars Thim, Eva H. N. Olsen, Kristine Øvlisen, Frederik Rode, C. N. Gudme, Søren E. Bjørn, Kristoffer W. Balling, Marianne Kjalke
المصدر: Blood. 121(11)
مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, Glycosylation, Time Factors, animal diseases, Immunology, CHO Cells, Pharmacology, Hemophilia A, Biochemistry, Models, Biological, law.invention, Polyethylene Glycols, Thrombosis and Hemostasis, Rats, Sprague-Dawley, Mice, Thrombin, Cricetulus, Von Willebrand factor, In vivo, law, hemic and lymphatic diseases, Cricetinae, PEG ratio, medicine, Potency, Animals, Humans, Cells, Cultured, Mice, Knockout, Factor VIII, biology, Chemistry, Chinese hamster ovary cell, Cell Biology, Hematology, Turoctocog alfa, Rats, Mice, Inbred C57BL, Disease Models, Animal, Treatment Outcome, biology.protein, Recombinant DNA, Female, Rabbits, medicine.drug
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5
المؤلفون: Mette Dahl Andersen, Lars Christian Petersen, Brit B. Sørensen, Henrik Agersø, Henrik Østergaard, Thomas N. Krogh, Lene Hansen, Karin Knobe, Pernille Holm, Anette A. Pedersen, Mette B. Hermit, Kristoffer W. Balling, Torben Elm, Mikael Tranholm, Timothy C. Nichols, Flemming Möller, Jais Rose Bjelke, Jørn Meidahl Petersen, Mirella Ezban, Søren E. Bjørn, Marie Louise S. Christiansen, Haleh Ahmadian
المصدر: Blood. 118(8)
مصطلحات موضوعية: Male, medicine.medical_specialty, Swine, Immunology, Polyethylene glycol, Pharmacology, In Vitro Techniques, Biochemistry, Hemophilia B, Hemostatics, law.invention, Polyethylene Glycols, Thrombosis and Hemostasis, Factor IX, chemistry.chemical_compound, Mice, Dogs, law, In vivo, Polysaccharides, Internal medicine, PEG ratio, medicine, Thromboplastin, Animals, Humans, Hematology, Binding Sites, Half-life, Cell Biology, Mice, Mutant Strains, Recombinant Proteins, Disease Models, Animal, Kinetics, chemistry, Recombinant DNA, Swine, Miniature, Female, medicine.drug, Half-Life
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6
المصدر: Thrombosis and Haemostasis. 104:860-861
مصطلحات موضوعية: Heterozygote, Protein Folding, Glycosylation, Endoplasmic Reticulum, Chlorocebus aethiops, Animals, Humans, Protein Isoforms, Medicine, Transgenes, Genetics, Brefeldin A, biology, business.industry, Haplotype, Factor V, Vascular biology, Heterozygote advantage, Hematology, Protein Transport, Haplotypes, COS Cells, Mutation, Mutation (genetic algorithm), biology.protein, business