المؤلفون: Agathe Hugele, Susanne Löffler, Belén Hernández Molina, Melina Guillon, Ahmed B. Montaser, Seppo Auriola, Kristiina M. Huttunen

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: amide, bioconversion, brain-targeted drug delivery, L-type amino acid transporter 1 (LAT1), peptidases, prodrug, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1034964/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/cce3d5a18df2438abe6395b679fabb6b

المؤلفون: Johanna Huttunen, Kristiina M. Huttunen

المصدر: CHIMIA, Vol 76, Iss 5 (2022)

مصطلحات موضوعية: ATP-binding cassette (ABC), L-type amino acid transporter 1 (LAT1), multidrug resistance (MDR), prodrug, solute carrier (SLC), Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://chimia.ch/chimia/article/view/6032; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/5d6a9c538d0c483a9bad69c86e3becf7

المؤلفون: Arun Kumar Tonduru, Santosh Kumar Adla, Kristiina M. Huttunen, Thales Kronenberger, Antti Poso

المصدر: Molecules, Vol 27, Iss 23, p 8531 (2022)

مصطلحات موضوعية: organic anion transporting polypeptides (OATPs), molecular dynamics simulations, homology models, xenobiotic transporters, Solute-Carrier O (SLCO), Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/23/8531; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/b5627aceaa3e45db95d73e319836e7d6

المؤلفون: Johanna Huttunen, Santosh Kumar Adla, Magdalena Markowicz-Piasecka, Kristiina M. Huttunen

المصدر: Pharmaceutics, Vol 14, Iss 6, p 1234 (2022)

مصطلحات موضوعية: blood–brain barrier (BBB), brain drug delivery, prodrugs, solute carriers (SLCs), Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/6/1234; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/2d786106ae254fe3805260edccb678c3

المؤلفون: Johanna Huttunen, Mahmoud Agami, Janne Tampio, Ahmed B. Montaser, Kristiina M. Huttunen

المصدر: Molecules, Vol 27, Iss 1, p 37 (2021)

مصطلحات موضوعية: l-type amino acid transporter 1 (LAT1), targeted drug delivery, transporter study methodology, intracellular kinetics, amino acid homeostasis, transporter regulation, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/1/37; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/473ae7aa14484bb48954d43639de5632

المؤلفون: Magdalena Markowicz-Piasecka, Kristiina M. Huttunen, Joanna Sikora

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1309-1322 (2018)

مصطلحات موضوعية: Metformin, donepezil, Alzheimer’s disease, acetylcholinesterase, amyloid, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/6621bf7a7b6547f18d1d1f19b4ce9b86

المؤلفون: Santosh Kumar Adla, Arun Kumar Tonduru, Thales Kronenberger, Eva Kudova, Antti Poso, Kristiina M. Huttunen

المصدر: Molecules, Vol 26, Iss 18, p 5662 (2021)

مصطلحات موضوعية: neurosteroid, cellular uptake, Organic Anion Transporting Polypeptides (OATPs), docking, molecular modeling, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/18/5662; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/459abd0c191643a98e6ae5d8bfeffaa0

المؤلفون: Magdalena Markowicz-Piasecka, Adrianna Sadkowska, Joanna Sikora, Marlena Broncel, Kristiina M. Huttunen

المصدر: Pharmaceuticals, Vol 13, Iss 10, p 323 (2020)

مصطلحات موضوعية: hemostasis, coagulation, biguanide, metformin, endothelium, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/13/10/323; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/3603a4b1a3404ff0add683073ff503fc

المؤلفون: Ahmed Montaser, Marko Lehtonen, Mikko Gynther, Kristiina M. Huttunen

المصدر: Pharmaceutics, Vol 12, Iss 4, p 344 (2020)

مصطلحات موضوعية: membrane transport, transporters, neuro-inflammation, LAT1-utilizing pro-drugs, prostaglandin E2, targeted brain delivery, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/4/344; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/f242e94c50e34871bd6ab47eb65f2586

المؤلفون: Magdalena Markowicz-Piasecka, Kristiina M. Huttunen, Adrianna Sadkowska, Joanna Sikora

المصدر: Molecules, Vol 25, Iss 1, p 125 (2019)

مصطلحات موضوعية: endothelium, vascular smooth muscle, metformin, platelet, biguanides, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/1/125; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/82e734dc02ef4e168e667a9d2bf89ad4

المؤلفون: Katayun Bahrami, Juulia Järvinen, Tuomo Laitinen, Mika Reinisalo, Paavo Honkakoski, Antti Poso, Kristiina M. Huttunen, Jarkko Rautio

Relation: https://doi.org/10.5281/zenodo.6841457; https://doi.org/10.5281/zenodo.6841458; oai:zenodo.org:6841458

الاتاحة: https://doi.org/10.5281/zenodo.6841458

المؤلفون: Agnieszka Zajda, Joanna Sikora, Kristiina M. Huttunen, Magdalena Markowicz-Piasecka

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4132

مصطلحات موضوعية: biguanides, coagulation, haemostasis, metformin

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms23084132

الاتاحة: https://doi.org/10.3390/ijms23084132

المؤلفون: Magdalena Markowicz-Piasecka, Johanna Huttunen, Ahmed Montaser, Santosh Kumar Adla, Seppo Auriola, Marko Lehtonen, Kristiina M. Huttunen

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 14; Pages: 7727

مصطلحات موضوعية: breast cancer resistant protein (BCRP), ganciclovir (GCV), methotrexate (MTX), MCF-7/MDA-MB-231 human breast cancer cells, multidrug resistance (MDR)

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms22147727

الاتاحة: https://doi.org/10.3390/ijms22147727

المؤلفون: Magdalena Markowicz-Piasecka, Karol Sadowski, Johanna Huttunen, Joanna Sikora, Kristiina M. Huttunen

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 5642, p 5642 (2021)

مصطلحات موضوعية: metformin, sulfonamides, apoptosis, cellular uptake, cell cycle arrest, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/22/11/5642; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/259123b8b7a6442d8f6a862af637327e

الاتاحة: https://doi.org/10.3390/ijms22115642
https://doaj.org/article/259123b8b7a6442d8f6a862af637327e

المؤلفون: Johanna Huttunen, Thales Kronenberger, Ahmed B. Montaser, Adéla Králová, Tetsuya Terasaki, Antti Poso, Kristiina M. Huttunen

المصدر: Molecular Pharmaceutics. 20:1331-1346

مصطلحات موضوعية: Drug Discovery, Pharmaceutical Science, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6ea49607337940238490e97435d71981
https://doi.org/10.1021/acs.molpharmaceut.2c00948

المؤلفون: Katayun Bahrami, Juulia Järvinen, Tuomo Laitinen, Mika Reinisalo, Paavo Honkakoski, Antti Poso, Kristiina M. Huttunen, Jarkko Rautio

المصدر: Molecular Pharmaceutics. 20:206-218

مصطلحات موضوعية: Drug Delivery Systems, Blood-Brain Barrier, Phenylalanine, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Prodrugs, Biological Transport, Amino Acids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bc3c3e2892be8ef3d43334e6ffd537
https://doi.org/10.1021/acs.molpharmaceut.2c00594

المؤلفون: Julie A. Spicer, Kristiina M. Huttunen, Jiney Jose, Ivo Dimitrov, Hedieh Akhlaghi, Vivien R. Sutton, Ilia Voskoboinik, Joseph Trapani

المصدر: Journal of Medicinal Chemistry. 65:14305-14325

مصطلحات موضوعية: Cytotoxicity, Immunologic, Pore Forming Cytotoxic Proteins, Mice, Membrane Glycoproteins, Perforin, Drug Discovery, Animals, Molecular Medicine, Autoimmunity, Immunosuppressive Agents, T-Lymphocytes, Cytotoxic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d59e97a0f33776e239d024ffea01e8b
https://doi.org/10.1021/acs.jmedchem.2c01338

المؤلفون: Magdalena Markowicz-Piasecka, Ibrahim Komeil, Johanna Huttunen, Joanna Sikora, Kristiina M. Huttunen

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 7; Pages: 2389

مصطلحات موضوعية: biguanides, metformin, organic cation transporters (OCT), cellular uptake, cytotoxicity, apoptosis

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms21072389

الاتاحة: https://doi.org/10.3390/ijms21072389

المؤلفون: Hengjing Cui, Joshua D. Elford, Okko Alitalo, Paula Perez-Pardo, Janne Tampio, Kristiina M. Huttunen, Aletta Kraneveld, Markus M. Forsberg, Timo T. Myöhänen, Aaro J. Jalkanen

المصدر: Neurobiology of Aging.

مصطلحات موضوعية: Aging, General Neuroscience, Neurology (clinical), Geriatrics and Gerontology, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1e6584340bdecbc3ae792a8c16ea2e84
https://doi.org/10.1016/j.neurobiolaging.2023.05.007

المؤلفون: Ahmed Montaser, Johanna Huttunen, Sherihan Abdelhamid Ibrahim, Kristiina M. Huttunen

المصدر: Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)

مصطلحات موضوعية: Cytology, QH573-671

Relation: http://dx.doi.org/10.1155/2019/3528148; https://doaj.org/toc/1942-0900; https://doaj.org/toc/1942-0994; https://doaj.org/article/5906949ad9fb4749872c8aee35e22178

الاتاحة: https://doi.org/10.1155/2019/3528148
https://doaj.org/article/5906949ad9fb4749872c8aee35e22178