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1Academic Journal
المؤلفون: Al-Taie, Zahraa S., Coles, Simon J., Congreve, Aileen, Ford, Dylan, Green, Lucy, Horton, Peter N., Jones, Leigh F., Kett, Pippa, Kraehenbuehl, Rolf, Murphy, Patrick J., Tizzard, Graham J., Willmore, Niles B., Wright, Oliver T.
وصف الملف: application/pdf
Relation: https://orca.cardiff.ac.uk/id/eprint/171629/1/reactions-05-00027.pdf; Al-Taie, Zahraa S., Coles, Simon J., Congreve, Aileen, Ford, Dylan, Green, Lucy, Horton, Peter N., Jones, Leigh F., Kett, Pippa, Kraehenbuehl, Rolf, Murphy, Patrick J., Tizzard, Graham J., Willmore, Niles B. and Wright, Oliver T. https://orca.cardiff.ac.uk/view/cardiffauthors/A2374746O.html 2024. C2-Symmetric amino acid amide-derived organocatalysts. Reactions 5 (3) , pp. 567-586. 10.3390/reactions5030027 https://doi.org/10.3390/reactions5030027 file https://orca.cardiff.ac.uk/id/eprint/171629/1/reactions-05-00027.pdf
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2Academic Journal
المؤلفون: Al-Taie, Zahraa S., Coles, Simon J., Congreve, Aileen, Ford, Dylan, Green, Lucy, Horton, Peter N., Jones, Leigh F., Kett, Pippa, Kraehenbuehl, Rolf, Murphy, Patrick J., Tizzard, Graham J., Willmore, Niles B., Wright, Oliver T.
وصف الملف: text
Relation: https://eprints.soton.ac.uk/495355/1/reactions-05-00027.pdf; Al-Taie, Zahraa S., Coles, Simon J., Congreve, Aileen, Ford, Dylan, Green, Lucy, Horton, Peter N., Jones, Leigh F., Kett, Pippa, Kraehenbuehl, Rolf, Murphy, Patrick J., Tizzard, Graham J., Willmore, Niles B. and Wright, Oliver T. (2024) C2-symmetric amino acid amide-derived organocatalysts. Reactions, 5 (3), 567-586. (doi:10.3390/reactions5030027 ).
الاتاحة: https://eprints.soton.ac.uk/495355/
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3Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
المؤلفون: Chakroborty, Anand, Pritchard, Deiniol R. R., Bouillon, Marc E. E., Cervi, Anna, Kraehenbuehl, Rolf, Wild, Charlotte, Fenn, Caroline, Holdsworth, Peter, Capner, Colin, Padalino, Gilda, Forde-Thomas, Josephine E. E., Payne, Joseph, Smith, Brendan G. G., Fisher, Maggie, Lahmann, Martina, Docent i kemi, 1963, Baird, Mark S. S., Hoffmann, Karl F. F.
المصدر: Pharmaceutics. 15(7)
مصطلحات موضوعية: Fasciola hepatica, anthelmintic drug discovery, Hedera helix, saponins and hederagenin
وصف الملف: print
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4Dissertation/ Thesis
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5Academic Journal
المؤلفون: Al-Taie, Zahraa S., Bartholomew, Barbara, Coles, Simon J., Evans, Daniel M., Hollinshead, Jackie, Jones, Leigh F., Kraehenbuehl, Rolf, Murphy, Patrick J., Nash, Robert J., Penkova, Yana B., Tizzard, Graham J.
المصدر: Tetrahedron ; volume 128, page 133119 ; ISSN 0040-4020
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6Academic Journal
المؤلفون: Al-Taie, Zahraa S., Bartholomew, Barbara, Cartmell, Christopher, Froom, Richard, Kerr, Russell G., Kraehenbuehl, Rolf, Murphy, Paddy, Nash, Robert J., Penkova, Yana B., van Teijlingen, Alexander
المصدر: Al-Taie , Z S , Bartholomew , B , Cartmell , C , Froom , R , Kerr , R G , Kraehenbuehl , R , Murphy , P , Nash , R J , Penkova , Y B & van Teijlingen , A 2022 , ' Synthesis of (+)-(R)-Tiruchanduramine ' , Molecules , vol. 27 , no. 4 . https://doi.org/10.3390/molecules27041338
مصطلحات موضوعية: Synoicum macroglossum, beta-carboline, guanidines, tiruchanduramine
وصف الملف: application/pdf
الاتاحة: https://research.bangor.ac.uk/portal/en/researchoutputs/synthesis-of-rtiruchanduramine(7f2b04a3-4457-467e-a9ef-3ad26d853263).html
https://doi.org/10.3390/molecules27041338
https://research.bangor.ac.uk/ws/files/40872259/molecules_27_01338.pdf -
7Academic Journal
المؤلفون: Al-Taie, Zahraa S., Bartholomew, Barbara, Coles, Simon J., Evans, Daniel M., Hollinshead, Jackie, Jones, Leigh F., Kraehenbuehl, Rolf, Murphy, Patrick J., Nash, Robert J., Penkova, Yana B., Tizzard, Graham J.
وصف الملف: text
Relation: https://eprints.soton.ac.uk/471848/1/molecules_1675081_002_.docx; https://eprints.soton.ac.uk/471848/2/1_s2.0_S0040402022003970_main_1_.pdf; Al-Taie, Zahraa S., Bartholomew, Barbara, Coles, Simon J., Evans, Daniel M., Hollinshead, Jackie, Jones, Leigh F., Kraehenbuehl, Rolf, Murphy, Patrick J., Nash, Robert J., Penkova, Yana B. and Tizzard, Graham J. (2022) Cyclic guanidine containing amino acids that promote glucocerebrosidase. Tetrahedron, 123, [132959]. (doi:10.1016/j.tet.2022.132959 ).
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8Academic Journal
المؤلفون: Böckemeier, Lennart, Kraehenbuehl, Rolf, Keszthelyi, Andrea, Gasasira, M.U., Vernon, Ellen, Beardmore, Richard, Broberg Vågbø, C., Chaplin, Daniel, Collins, S., Krokan, H.E., Lambert, S.A.E., Paisz, B., Hartsuiker, Edgar
المصدر: Böckemeier , L , Kraehenbuehl , R , Keszthelyi , A , Gasasira , M U , Vernon , E , Beardmore , R , Broberg Vågbø , C , Chaplin , D , Collins , S , Krokan , H E , Lambert , S A E , Paisz , B & Hartsuiker , E 2020 , ' Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication ' , Science Advances , vol. 6 , no. 22 , eaaz4126 . https://doi.org/10.1126/sciadv.aaz4126
وصف الملف: application/pdf
الاتاحة: https://research.bangor.ac.uk/portal/en/researchoutputs/mre11-exonuclease-activity-removes-the-chainterminating-nucleoside-analog-gemcitabine-from-the-nascent-strand-during-dna-replication(e25601ea-0557-4b7c-84d2-4104b0f04c28).html
https://doi.org/10.1126/sciadv.aaz4126
https://research.bangor.ac.uk/ws/files/29066201/2020_Mre11_exonuclease_activity_removes_the_chain_terminating_nucleoside_analogue_Gemcitabine_from_the_nascent_strand_during_DNA_replication.pdf -
9Academic Journal
المؤلفون: Al-Taie, Zahraa S, Bartholomew, Barbara, Coles, Simon J, Evans, Daniel M, Hollinshead, Jackie, Jones, Leigh F, Kraehenbuehl, Rolf, Murphy, Patrick J, Nash, Robert J, Penkova, Yana B, Tizzard, Graham J
المساهمون: School of Biological, Physical and Forensic Sciences, The University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, UK
المصدر: 123 ; 1
مصطلحات موضوعية: cyclic guanidines, glycosidase inhibitors, glycosidase promoters, N-methylation
وصف الملف: application/pdf
Relation: https://www.sciencedirect.com/science/article/pii/S0040402022003970?via%3Dihub#!; Al-Taie, Z. S., Bartholomew, B., Coles, S. J., Evans, D. M. et al. (2022) Cyclic guanidine containing amino acids that promote glucocerebrosidase, Tetrahedron, 123, Article No. 132959. DOI:10.1016/j.tet.2022.132959; http://hdl.handle.net/2436/624914; Tetrahedron; 132959
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10Academic Journal
المؤلفون: Murphy, Patrick Joseph, Al-Taie, Zahraa S., Bartholomew, Barbara, Coles, Simon J., Hollinshead, Jackie, Jones, Leigh F., Kraehenbuehl, Rolf, Nash, Robert J., Penkova, Yana B., Tizzard, Graham J., Evans, Daniel M.
المصدر: SSRN Electronic Journal ; ISSN 1556-5068
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11Academic Journal
المؤلفون: Zhou, Zheng, Humphryes, Neil, Van Eijk, Patrick, Waters, Raymond, Yu, Shirong, Kraehenbuehl, Rolf, Hartsuiker, Edgar, Reed, Simon H.
مصطلحات موضوعية: R Medicine (General)
وصف الملف: application/pdf
Relation: https://orca.cardiff.ac.uk/id/eprint/84172/1/SReed2.pdf; Zhou, Zheng, Humphryes, Neil, Van Eijk, Patrick https://orca.cardiff.ac.uk/view/cardiffauthors/A2116016T.html orcid:0000-0001-9549-555X orcid:0000-0001-9549-555X, Waters, Raymond, Yu, Shirong, Kraehenbuehl, Rolf, Hartsuiker, Edgar and Reed, Simon H. https://orca.cardiff.ac.uk/view/cardiffauthors/A046523V.html orcid:0000-0002-4711-0560 orcid:0000-0002-4711-0560 2015. UV induced ubiquitination of the yeast Rad4–Rad23 complex promotes survival by regulating cellular dNTP pools. Nucleic Acids Research 43 (15) , pp. 7360-7370. 10.1093/nar/gkv680 https://doi.org/10.1093/nar%2Fgkv680 file https://orca.cardiff.ac.uk/id/eprint/84172/1/SReed2.pdf
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12Academic Journal
المؤلفون: Rack, Johannes G M, Morra, Rosa, Barkauskaite, Eva, Kraehenbuehl, Rolf, Ariza, Antonio, Qu, Yue, Ortmayer, Mary, Leidecker, Orsolya, Cameron, David R, Matic, Ivan, Peleg, Anton Y, Leys, David, Traven, Ana, Ahel, Ivan
المصدر: Rack , J G M , Morra , R , Barkauskaite , E , Kraehenbuehl , R , Ariza , A , Qu , Y , Ortmayer , M , Leidecker , O , Cameron , D R , Matic , I , Peleg , A Y , Leys , D , Traven , A & Ahel , I 2015 , ' Identification of a class of protein ADP-Ribosylating sirtuins in microbial pathogens ' , Molecular Cell , vol. 59 , no. 2 , pp. 309 - 320 . https://doi.org/10.1016/j.molcel.2015.06.013
وصف الملف: application/pdf
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13Academic Journal
المؤلفون: Chen, Dawei, Vollmar, Melanie, Rossi, Marianna N., Phillips, Claire, Kraehenbuehl, Rolf, Slade, Dea, Mehrotra, Pawan V., von Delft, Frank, Crosthwaite, Susan K., Gileadi, Opher, Denu, John M., Ahel, Ivan
المصدر: Journal of Biological Chemistry ; volume 286, issue 15, page 13261-13271 ; ISSN 0021-9258
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14Academic Journal
المؤلفون: Mehrotra, Pawan Vinod, Ahel, Dragana, Ryan, Daniel P., Weston, Ria, Wiechens, Nicola, Kraehenbuehl, Rolf, Owen-Hughes, Tom, Ahel, Ivan
المصدر: Molecular Cell ; volume 41, issue 1, page 46-55 ; ISSN 1097-2765
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15Academic Journal
المصدر: Grishchuk, Alexandra L.; Kraehenbuehl, Rolf; Molnar, Monika; Fleck, Oliver; Kohli, Juerg (2004). Genetic and cytological characterization of the RecA-homologous proteins Rad51 and Dmc1 of Schizosaccharomyces pombe. Current genetics, 44(6), pp. 317-328. Springer-Verlag 10.1007/s00294-003-0439-7
مصطلحات موضوعية: 570 Life sciences, biology
وصف الملف: application/pdf
Relation: https://boris.unibe.ch/117548/
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16
المؤلفون: Tubbs, Julie L., Latypov, Vitaly, Kanugula, Sreenivas, Butt, Amna, Melikishvili, Manana, Kraehenbuehl, Rolf, Fleck, Oliver, Marriott, Andrew, Watson, Amanda J., Verbeek, Barbara, McGown, Gail, Thorncroft, Mary, Santibanez-Koref, Mauro F., Millington, Christopher, Arvai, Andrew S., Kroeger, Matthew D., Peterson, Lisa A., Williams, David M., Fried, Michael G., Margison, Geoffrey P., Pegg, Anthony E., Tainer, John A.
المصدر: Nature
مصطلحات موضوعية: Models, Molecular, Alkyl and Aryl Transferases, Binding Sites, Guanine, Alkylation, DNA Repair, Protein Conformation, DNA, Crystallography, X-Ray, Article, parasitic diseases, Humans, DNA Damage, Protein Binding
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17Academic Journal
المؤلفون: Tumbale, Percy, Appel, C. Denise, Kraehenbuehl, Rolf, Robertson, Patrick D., Williams, Jessica S., Krahn, Joe, Ahel, Ivan, Williams, R. Scott
المصدر: Tumbale , P , Appel , C D , Kraehenbuehl , R , Robertson , P D , Williams , J S , Krahn , J , Ahel , I & Williams , R S 2011 , ' Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease ' , Nature Structural and Molecular Biology , vol. 18 , no. 11 , pp. 1189-1195 . https://doi.org/10.1038/nsmb.2146
مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre
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18Academic Journal
المؤلفون: Tubbs, Julie L, Latypov, Vitaly F, Kanugula, Sreenivas, Butt, Amna, Melikishvili, Manana, Kraehenbuehl, Rolf, Fleck, Oliver, Marriott, Andrew S, Watson, Amanda J, Verbeek, Barbara, McGown, Gail, Thorncroft, Mary R, Santibanez-Koref, Mauro F, Millington, Christopher, Arvai, Andrew S, Kroeger, Matthew D, Peterson, Lisa A, Williams, David M, Fried, Mike, Margison, Geoffrey P, Pegg, Anthony E, Tainer, John A
المساهمون: Skaggs Institute for Chemical Biology and Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
مصطلحات موضوعية: Alkyl and Aryl Transferases, Alkylation, Binding Sites, Crystallography, X-Ray, DNA, DNA Damage, DNA Repair, Guanine, Humans, Models, Molecular, Protein Binding, Protein Conformation
Relation: Flipping of alkylated DNA damage bridges base and nucleotide excision repair. 2009, 459 (7248):808-13 Nature; http://hdl.handle.net/10541/85244; Nature
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19Academic Journal
المؤلفون: Lettieri, Teresa, Kraehenbuehl, Rolf, Capiaghi, Christoph, Livingstone-Zatchej, Magdalena, Thoma, Fritz
المصدر: DNA Repair ; volume 7, issue 5, page 734-743 ; ISSN 1568-7864
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20Academic Journal
المؤلفون: Kölliker, Roland, Kraehenbuehl, Rolf, Boller, Beat, Widmer, Franco
المصدر: Systematic and Applied Microbiology ; volume 29, issue 2, page 109-119 ; ISSN 0723-2020