نتائج البحث - "Kostewicz, Edmund S."

1

Academic Journal

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs:A PEARRL Review

المؤلفون: Litou, Chara, Effinger, Angela, Kostewicz, Edmund S., Box, Karl J., Fotaki, Nikoletta, Dressman, Jennifer B.

المصدر: Litou , C , Effinger , A , Kostewicz , E S , Box , K J , Fotaki , N & Dressman , J B 2019 , ' Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs : A PEARRL Review ' , Pharmacy and Pharmacology Communications , vol. 71 , no. 4 , pp. 643-673 . https://doi.org/10.1111/jphp.12983

مصطلحات موضوعية: Drug-drug interaction, GI motility, GI pH, Metabolism, Permeability, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/3000/3003, name=Pharmaceutical Science

وصف الملف: application/pdf

الاتاحة: https://researchportal.bath.ac.uk/en/publications/bccd3451-262b-4775-aaf4-d9a17133aa57
https://doi.org/10.1111/jphp.12983
https://purehost.bath.ac.uk/ws/files/185394836/PK_interactions_co_medication_GI_diesease_PEARRL_review_Dr_N_Fotaki.pdf
http://www.scopus.com/inward/record.url?scp=85051049807&partnerID=8YFLogxK

View record in BASE

2

Academic Journal

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review

المؤلفون: Henze, Laura J, Koehl, Niklas J, O'Shea, Joseph P, Kostewicz, Edmund S, Holm, René, Griffin, Brendan T

المساهمون: Horizon 2020 Marie Sklodowska-Curie Innovative Training Networks programme

المصدر: Journal of Pharmacy and Pharmacology ; volume 71, issue 4, page 581-602 ; ISSN 2042-7158 0022-3573

الاتاحة: https://doi.org/10.1111/jphp.12912
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjphp.12912
https://academic.oup.com/jpp/article-pdf/71/4/581/60227242/jphp12912.pdf

View record in BASE

3

Academic Journal

In vitro methods to assess drug precipitation in the fasted small intestine – a PEARRL review

المؤلفون: O'Dwyer, Patrick J, Litou, Chara, Box, Karl J, Dressman, Jennifer B, Kostewicz, Edmund S, Kuentz, Martin, Reppas, Christos

المساهمون: European Union's Horizon 2020 Research and Innovation Programme

المصدر: Journal of Pharmacy and Pharmacology ; volume 71, issue 4, page 536-556 ; ISSN 2042-7158 0022-3573

الاتاحة: http://dx.doi.org/10.1111/jphp.12951
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjphp.12951
http://academic.oup.com/jpp/article-pdf/71/4/536/36592328/jphp12951.pdf

View record in BASE

4

Academic Journal

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

المؤلفون: Darwich, Adam, Aarons, Leon, Galetin, Aleksandra, Rostami-Hochaghan Amin, Margolskee, Alison, Pepin, Xavier, Carlert, Sara, Hammarberg, Maria, Hilgendorf, Constanze, Johansson, Pernilla, Karlsson, Eva, Murphy, Donal, Tannergren, Christer, Thorn, Helena, Yasin, Mohammed, Mazuir, Florent, Nicolas, Olivier, Ramusovic, Sergej, Xu, Christine, Pathak, Shriram, Korjamo, Timo, Laru, Johanna, Malkki, Jussi, Pappinen, Sari, Tuunainen, Johanna, Dressman, Jennifer, Hansmann, Simone, Kostewicz, Edmund S., He, Handan, Heimbach, Tycho, Wu, Fan, Hoft, Carolin, Pang, Yan, Bolger, Michael, Huehn, Eva, Bolger, Michael B., Lukacova, Viera, Mullin, James M., Szeto, Ke X., Costales, Chester, Lin, Jian, McAllister, Mark, Modi, Sweta, Rotter, Charles, Varma, Manthena, Wong, Mei, Mitra, Amitava, Bevernage, Jan, Biewenga, Jeike, Peer, Achiel Van, Lloyd, Richard, Shardlow, Carole, Langguth, Peter, Mishenzon, Irina, Nguyen, Mai Anh, Brown, Jonathan, Lennerans, Hans, Abrahmsson, Bertil

المصدر: Darwich , A , Aarons , L , Galetin , A , Rostami-Hochaghan et al , A , Margolskee , A , Pepin , X , Carlert , S , Hammarberg , M , Hilgendorf , C , Johansson , P , Karlsson , E , Murphy , D , Tannergren , C , Thorn , H , Yasin , M , Mazuir , F , Nicolas , O , Ramusovic , S , Xu , C , Pathak , S , Korjamo , T , Laru , J , Malkki , J , Pappinen , S , Tuunainen ....

وصف الملف: application/pdf

الاتاحة: https://research.manchester.ac.uk/en/publications/8ec46268-9deb-4899-bf9c-53be1ada2d02
https://doi.org/10.1016/j.ejps.2016.09.037
https://pure.manchester.ac.uk/ws/files/46273976/Darwich_2016_IMI_ORBITO_3.pdf

View record in BASE

5

Academic Journal

Model-based analysis of biopharmaceutic experiments to improve mechanistic oral absorption modeling : an integrated in vitro in vivo extrapolation perspective using Ketoconazole as a model drug

المؤلفون: Pathak, Shriram M., Ruff, Aaron, Kostewicz, Edmund S., Patel, Nikunjkumar, Turner, David B., Jamei, Masoud

مصطلحات موضوعية: ddc:610

وصف الملف: application/pdf

Relation: http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46879; urn:nbn:de:hebis:30:3-468797; https://nbn-resolving.org/urn:nbn:de:hebis:30:3-468797; https://doi.org/10.1021/acs.molpharmaceut.7b00406; http://publikationen.ub.uni-frankfurt.de/files/46879/acs.molpharmaceut.7b00406.pdf

الاتاحة: http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46879
https://nbn-resolving.org/urn:nbn:de:hebis:30:3-468797
https://doi.org/10.1021/acs.molpharmaceut.7b00406
http://publikationen.ub.uni-frankfurt.de/files/46879/acs.molpharmaceut.7b00406.pdf

View record in BASE

6

The use of the pig as an animal model for the prediction of drug bioavailability in humans

المؤلفون: Kostewicz, Edmund S.

مصطلحات موضوعية: Drugs, Swine

الاتاحة: http://arrow.unisa.edu.au:8081/1959.8/85214
http://arrow.unisa.edu.au/vital/access/manager/Repository/unisa:42697

View record in Networked Digital Library of Theses & Dissertations

7

Academic Journal

A combined in vitro in-silico approach to predict the oral bioavailability of borderline BCS Class II/IV weak base albendazole and its main metabolite albendazole sulfoxide

المؤلفون: Pettarin, Maximo, Bolger, Michael B., Chronowska, Maja, Kostewicz, Edmund S.

المصدر: European Journal of Pharmaceutical Sciences ; volume 155, page 105552 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2020.105552
https://api.elsevier.com/content/article/PII:S0928098720303407?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0928098720303407?httpAccept=text/plain

View record in BASE

8

PBPK models for the prediction of in vivo performance of oral dosage forms

المؤلفون: Kostewicz, Edmund S., Aarons, Leon, Bergstrand, Martin, Bolger, Michael B., Galetin, Aleksandra, Hatley, Oliver, Jamei, Masoud, Lloyd, Richard, Pepin, Xavier, Rostami-Hodjegan, Amin, Sjogren, Erik, Tannergren, Christer, Turner, David B., Wagner, Christian, Weitschies, Werner, Dressman, Jennifer

المصدر: European Journal of Pharmaceutical Sciences. 57(SI):300-321

مصطلحات موضوعية: Physiologically-based pharmacokinetic (PBPK) models, Predicting drug absorption, Innovative Medicines Initiative (IMI), Oral Biopharmaceutical Tools (OrBiTo), In vitro biopharmaceutical tools, Gastrointestinal physiology

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-228424

9

Academic Journal

Evaluating the predictability of the in vitro transfer model and in vivo rat studies as a surrogate to investigate the supersaturation and precipitation behaviour of different Albendazole formulations for humans

المؤلفون: Ruff, Aaron, Holm, René, Kostewicz, Edmund S.

المساهمون: Innovative Medicines Initiative Joint Undertaking, European Union Seventh Framework Program

المصدر: European Journal of Pharmaceutical Sciences ; volume 105, page 108-118 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2017.04.024
https://api.elsevier.com/content/article/PII:S0928098717302282?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0928098717302282?httpAccept=text/plain

View record in BASE

10

Academic Journal

Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling

المؤلفون: Ruff, Aaron, Fiolka, Tom, Kostewicz, Edmund S.

المساهمون: Innovative Medicines Initiative Joint Undertaking, Seventh Framework Program

المصدر: European Journal of Pharmaceutical Sciences ; volume 100, page 42-55 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2016.12.017
https://api.elsevier.com/content/article/PII:S0928098716305577?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0928098716305577?httpAccept=text/xml

View record in BASE

11

Composition of the Small Intestinal Contents Under Fasting and Fed Conditions

المؤلفون: Kostewicz, Edmund S.

المصدر: Oral Drug Delivery for Modified Release Formulations ; page 11-17 ; ISBN 9781119772699 9781119772729

الاتاحة: http://dx.doi.org/10.1002/9781119772729.ch1b
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781119772729.ch1b

View record in BASE

12

The Role and Applications of Dissolution Media for the Investigation of Modified‐Release Formulations

المؤلفون: Andreas, Cord J., Kostewicz, Edmund S.

المصدر: Oral Drug Delivery for Modified Release Formulations ; page 273-287 ; ISBN 9781119772699 9781119772729

الاتاحة: http://dx.doi.org/10.1002/9781119772729.ch15
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781119772729.ch15

View record in BASE

13

Academic Journal

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: a PEARRL Review.

المؤلفون: Litou, Chara, Effinger, Angela, Kostewicz, Edmund S., Box, Karl J., Fotaki, Nikoletta, Dressman, Jennifer B.

المصدر: Journal of Pharmacy & Pharmacology; Apr2019, Vol. 71 Issue 4, p643-673, 31p

مصطلحات موضوعية: GASTROINTESTINAL disease treatment, DRUG efficacy, PHARMACOKINETICS, NONPRESCRIPTION drugs, ORAL medication, METOCLOPRAMIDE

14

Academic Journal

In vitro methods to assess drug precipitation in the fasted small intestine – a PEARRL review.

المؤلفون: O'Dwyer, Patrick J., Litou, Chara, Box, Karl J., Dressman, Jennifer B., Kostewicz, Edmund S., Kuentz, Martin, Reppas, Christos

المصدر: Journal of Pharmacy & Pharmacology; Apr2019, Vol. 71 Issue 4, p536-556, 21p

مصطلحات موضوعية: SMALL intestine, PHARMACEUTICAL industry, DRUG development, BIOPHARMACEUTICS, COUPLING reactions (Chemistry)

15

Academic Journal

Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments

المؤلفون: O’Shea, Joseph P., Faisal, Waleed, Ruane-O’Hora, Therese, Devine, Ken J., Kostewicz, Edmund S., O’Driscoll, Caitriona M., Griffin, Brendan T.

المصدر: European Journal of Pharmaceutics and Biopharmaceutics ; volume 96, page 207-216 ; ISSN 0939-6411

الاتاحة: http://dx.doi.org/10.1016/j.ejpb.2015.07.014
https://api.elsevier.com/content/article/PII:S0939641115003033?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0939641115003033?httpAccept=text/plain

View record in BASE

16

Academic Journal

In vitro models for the prediction of in vivo performance of oral dosage forms

المؤلفون: Kostewicz, Edmund S, Abrahamsson, Bertil, Brewster, Marcus, Brouwers, Joachim, Butler, James, Carlert, Sara, Dickinson, Paul A, Dressman, Jennifer, Holm, René, Klein, Sandra, Mann, James, McAllister, Mark, Minekus, Mans, Muenster, Uwe, Müllertz, Anette, Verwei, Miriam, Vertzoni, Maria, Weitschies, Werner, Augustijns, Patrick

المصدر: Kostewicz , E S , Abrahamsson , B , Brewster , M , Brouwers , J , Butler , J , Carlert , S , Dickinson , P A , Dressman , J , Holm , R , Klein , S , Mann , J , McAllister , M , Minekus , M , Muenster , U , Müllertz , A , Verwei , M , Vertzoni , M , Weitschies , W & Augustijns , P 2014 , ' In vitro models for the prediction of in vivo performance of oral dosage forms ' , European Journal of ....

الاتاحة: https://researchprofiles.ku.dk/da/publications/in-vitro-models-for-the-prediction-of-in-vivo-performance-of-oral-dosage-forms(93f95602-51b8-4126-aacc-567b92c2dcd8).html
https://doi.org/10.1016/j.ejps.2013.08.024

View record in BASE