المؤلفون: Schimmel, Joost, Muñoz-Subirana, Núria, Kool, H, van Schendel, Robin, van der Vlies, Sven, Kamp, Juliette, de Vrij, Femke, Kushner, Steven, Smith, Graeme C.M., Boulton, SJ, Tijsterman, Marcel

المصدر: Schimmel , J , Muñoz-Subirana , N , Kool , H , van Schendel , R , van der Vlies , S , Kamp , J , de Vrij , F , Kushner , S , Smith , G C M , Boulton , SJ & Tijsterman , M 2023 , ' Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways ' , Cell Reports , vol. 42 , no. 2 , 112019 . https://doi.org/10.1016/j.celrep.2023.112019

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/13c5895e-25ca-427c-826b-f13719a0c5e2
https://doi.org/10.1016/j.celrep.2023.112019
https://pure.eur.nl/ws/files/81366710/Modulating_mutational_outcomes_and_improving_precise_gene_editing_at_CRISPR_Cas9_induced_breaks_by_chemical_inhibition_of_end_joining_pathways.pdf
http://www.scopus.com/inward/record.url?scp=85146842806&partnerID=8YFLogxK

المؤلفون: Zelenskyy, Alex, Schimmel, J, Kool, H, Kanaar, Roland, Tijsterman, M

المصدر: Zelenskyy , A , Schimmel , J , Kool , H , Kanaar , R & Tijsterman , M 2017 , ' Inactivation of Pol theta and C-NHEJ eliminates off-target integration of exogenous DNA ' , Nature Communications , vol. 8 , 66 . https://doi.org/10.1038/s41467-017-00124-3

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCOR01, name=EMC OR-01

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/8d820b0b-6427-4166-bfea-b1707c34cd09
https://doi.org/10.1038/s41467-017-00124-3
https://pure.eur.nl/ws/files/47822435/REPUB_108584_OA.pdf
http://hdl.handle.net/1765/108584

المؤلفون: Sampadi, B., Vermeulen, S., Misovic, B., Boei, J.J., Batth, T.S., Chang, J.G., Paulsen, M.T., Magnuson, B., Schimmel, J., Kool, H., Olie, C.S., Everts, B., Vertegaal, A.C.O., Olsen, J.V., Ljungman, M., Jeggo, P.A., Mullenders, L.H.F., Vrieling, H.

المصدر: Cells

مصطلحات موضوعية: ionizing radiation, low dose, linear no-threshold, signal transduction, cell signaling, DNA damage response, phosphoproteomics, mitochondria, reactive oxygen species, antioxidant response

وصف الملف: application/pdf

Relation: lumc-id: 175905489; https://hdl.handle.net/1887/3563900

الاتاحة: https://hdl.handle.net/1887/3563900
https://doi.org/10.3390/cells11233794

المؤلفون: Kool, H.

الاتاحة: http://data.europeana.eu/aggregation/europeana/2021626/AtlantisPubliek_detail_aspx_xmldescid_765287

المؤلفون: Zoeteman, B. C. J., Hrubec, J., de Greef, E., Kool, H. J.

المصدر: Environmental Health Perspectives, 1982 Dec 01. 46, 197-205.

URL الوصول: https://www.jstor.org/stable/3429438

المؤلفون: Kool, H. J., van Kreijl, C. F., de Greef, E., van Kranen, H. J.

المصدر: Environmental Health Perspectives, 1982 Dec 01. 46, 207-214.

URL الوصول: https://www.jstor.org/stable/3429439

المؤلفون: Schimmel, J., Munoz Subirana, N., Kool, H., Schendel, R. van, Tijsterman, M.

المصدر: Nature Communications

وصف الملف: application/pdf

Relation: https://www.nature.com/articles/s41467-021-25154-w.pdf; lumc-id: 120528957; https://hdl.handle.net/1887/3213879

الاتاحة: https://hdl.handle.net/1887/3213879
https://www.nature.com/articles/s41467-021-25154-w.pdf
https://doi.org/10.1038/s41467-021-25154-w

المؤلفون: Brandt, M M, Van Dijk, CGM, Chrifi, I, Kool, H M, Louzao-Martinez, L, Pei, J, Rottier, R J, Verhaar, M C, Duncker, D J, Cheng, C

المصدر: Cardiovascular Research ; volume 114, issue suppl_1, page S91-S92 ; ISSN 0008-6363 1755-3245

مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine, Physiology

الاتاحة: http://dx.doi.org/10.1093/cvr/cvy060.268
http://academic.oup.com/cardiovascres/article-pdf/114/suppl_1/S91/24692064/cvy060.268.pdf

المؤلفون: Schimmel, J., Kool, H., Schendel, R. van, Tijsterman, M.

المصدر: EMBO Journal

مصطلحات موضوعية: cNHEJ, CRISPR/Cas9, double-strand break repair, embryonic stem cells, polymerase theta-mediated end joining

Relation: lumc-id: 42353596; https://hdl.handle.net/1887/116012

الاتاحة: https://hdl.handle.net/1887/116012
https://doi.org/10.15252/embj.201796948

المؤلفون: Kool, H. J., van Kranen, H. J.

المصدر: Monographs in Virology ; Enteric Viruses in Water ; page 134-145 ; ISSN 0077-0965 1662-3851 ; ISBN 9783805538039 9783318040371

الاتاحة: http://dx.doi.org/10.1159/000409130
https://www.karger.com/Article/Pdf/409130
http://www.karger.com/Article/Pdf/409130

المؤلفون: Kool, H, Mous, D, Tibboel, Dick, de Klein, Annelies, Rottier, Robbert

المصدر: Kool , H , Mous , D , Tibboel , D , de Klein , A & Rottier , R 2014 , ' Pulmonary Vascular Development Goes Awry in Congenital Lung Abnormalities ' , Birth defects research part C-embryo today-reviews , vol. 102 , no. 4 , pp. 343-358 . https://doi.org/10.1002/bdrc.21085

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMGC021303, name=EMC MGC-02-13-03, /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMGC025301A, name=EMC MGC-02-53-01-A, /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMGC029601, name=EMC MGC-02-96-01, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الاتاحة: https://pure.eur.nl/en/publications/90087e0b-c4a8-43a0-93d3-d146b3d6acdf
https://doi.org/10.1002/bdrc.21085
http://hdl.handle.net/1765/82404

المؤلفون: Ochieng, J.K., Schilders, K., Kool, H., Boerema- de Munck, A., Kempen, M. van, Gontan, C., Smits, R., Grosveld, F.G., Wijnen, R.M.H., Tibboel, D., Rottier, R.J.

المصدر: American Journal of Respiratory Cell and Molecular Biology, 51, 2, pp. 311-22

مصطلحات موضوعية: Radboudumc 9: Rare cancers RIMLS: Radboud Institute for Molecular Life Sciences

Relation: http://hdl.handle.net/2066/136849

الاتاحة: http://hdl.handle.net/2066/136849
https://doi.org/10.1165/rcmb.2013-0419OC

المؤلفون: Anindya, R, Mari, PO, Kristensen, U, Kool, H, Giglia, GC, Mullenders, LH, Fousteri, M, Vermeulen, Wim, Egly, JM, Svejstrup, JQ

المصدر: Anindya , R , Mari , PO , Kristensen , U , Kool , H , Giglia , GC , Mullenders , LH , Fousteri , M , Vermeulen , W , Egly , JM & Svejstrup , JQ 2010 , ' A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair ' , Molecular Cell , vol. 38 , no. 5 , pp. 637-648 . https://doi.org/10.1016/j.molcel.2010.04.017

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMGC011203, name=EMC MGC-01-12-03

الاتاحة: https://pure.eur.nl/en/publications/8435e0a0-b072-47d8-97f0-d23b82640753
https://doi.org/10.1016/j.molcel.2010.04.017
http://hdl.handle.net/1765/28259

المؤلفون: Overmeer, RM, Gourdin, Audrey, Giglia, GC, Kool, H, Houtsmuller, Adriaan, Siegal, G, Fousteri, MI, Mullenders, LHF, Vermeulen, Wim

المصدر: Overmeer , RM , Gourdin , A , Giglia , GC , Kool , H , Houtsmuller , A , Siegal , G , Fousteri , MI , Mullenders , LHF & Vermeulen , W 2010 , ' Replication Factor C Recruits DNA Polymerase delta to Sites of Nucleotide Excision Repair but Is Not Required for PCNA Recruitment ' , Molecular and Cellular Biology , vol. 30 , no. 20 , pp. 4828-4839 . https://doi.org/10.1128/MCB.00285-10

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMGC011203, name=EMC MGC-01-12-03, /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMM032401, name=EMC MM-03-24-01

الاتاحة: https://pure.eur.nl/en/publications/ce2fc61b-2c18-4342-a0da-f039b8c77ea6
https://doi.org/10.1128/MCB.00285-10
http://hdl.handle.net/1765/69381

المؤلفون: Luijsterburg, M.S., Goedhart, J., Moser, J., Kool, H., Geverts, B., Houtsmuller, A.B., Mullenders, L.H., Vermeulen, W., van Driel, R.

المصدر: Luijsterburg , M S , Goedhart , J , Moser , J , Kool , H , Geverts , B , Houtsmuller , A B , Mullenders , L H , Vermeulen , W & van Driel , R 2007 , ' Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC. ' , Journal of Cell Science , vol. 120 , no. 15 , pp. 2706-2716 . https://doi.org/10.1242/jcs.008367

الاتاحة: https://dare.uva.nl/personal/pure/en/publications/dynamic-in-vivo-interaction-of-ddb2-e3-ubiquitin-ligase-with-uvdamaged-dna-is-independent-of-damagerecognition-protein-xpc(c1e91dc9-1f23-486c-958e-5f57313778eb).html
https://doi.org/10.1242/jcs.008367

المؤلفون: Moser, J, Volker, M, Kool, H, Alekseev, S, Vrieling, H, Yasui, A, van Zeeland, AA, Mullenders, LHF

المصدر: Moser , J , Volker , M , Kool , H , Alekseev , S , Vrieling , H , Yasui , A , van Zeeland , AA & Mullenders , LHF 2005 , ' The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions ' , Dna repair , vol. 4 , no. 5 , pp. 571-582 . https://doi.org/10.1016/j.dnarep.2005.01.001

مصطلحات موضوعية: UV-damaged DNA binding protein, xeroderma pigmentosum group E, 6-4 photoproducts, cylcobutane pyrimidine dimmers, nucleotide excision repair, PIGMENTOSUM GROUP-E, CYCLOBUTANE PYRIMIDINE DIMERS, GLOBAL GENOMIC REPAIR, GROUP-E CELLS, IN-VIVO, GENE-PRODUCT, P48 SUBUNIT, DDB2 GENE, IRRADIATION, XPC

الاتاحة: https://hdl.handle.net/11370/38fb4b52-3f34-4a21-8fea-7edb18fdc1cf
https://research.rug.nl/en/publications/38fb4b52-3f34-4a21-8fea-7edb18fdc1cf
https://doi.org/10.1016/j.dnarep.2005.01.001

المؤلفون: Alekseev, S, Kool, H, Rebel, H, Fousteri, M, Moser, J, Backendorf, C, de Gruijl, FR, Vrieling, H, Mullenders, LHF

المصدر: Alekseev , S , Kool , H , Rebel , H , Fousteri , M , Moser , J , Backendorf , C , de Gruijl , FR , Vrieling , H & Mullenders , LHF 2005 , ' Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation ' , Cancer Research , vol. 65 , no. 22 , pp. 10298-10306 . https://doi.org/10.1158/0008-5472.CAN-05-2295

مصطلحات موضوعية: DNA-BINDING-PROTEIN, CYCLOBUTANE PYRIMIDINE DIMERS, NUCLEOTIDE EXCISION-REPAIR, PIGMENTOSUM GROUP-E, TRANSCRIPTION-COUPLED REPAIR, GLOBAL GENOMIC REPAIR, XERODERMA-PIGMENTOSUM, DAMAGED-DNA, INDUCED APOPTOSIS, COCKAYNE-SYNDROME

Relation: https://research.rug.nl/en/publications/9bed4260-3707-4da8-9132-12cd959016ab

الاتاحة: https://hdl.handle.net/11370/9bed4260-3707-4da8-9132-12cd959016ab
https://research.rug.nl/en/publications/9bed4260-3707-4da8-9132-12cd959016ab
https://doi.org/10.1158/0008-5472.CAN-05-2295

المؤلفون: Kool, H.

مصطلحات الفهرس: agro-industriële ketens, agro-industrial chains, agro-industriële sector, agroindustrial sector, ketenmanagement, supply chain management, dierenwelzijn, animal welfare, veehouderij, livestock farming, dierlijke productie, animal production, 217-I Beheer van productieketens, 217-I Production Chain Management, Presentation

URL: https://edepot.wur.nl/198860
https://edepot.wur.nl/198860

المؤلفون: Lenders, S., Stark, M., Kool, H.

مصطلحات الفهرس: sportterreinen, sports grounds, neerslag, precipitation, afvoer, discharge, sportveldgronden, sports turf soils, kaderrichtlijn water, water framework directive, bodemwater, soil water, 502-E Graslanden, 502-E Grasslands, 208-C Sport, Article

URL: https://edepot.wur.nl/339749
https://edepot.wur.nl/339749

المؤلفون: Kool, H.

مصطلحات الفهرس: pluimveehouderij, poultry farming, huisvesting van kippen, chicken housing, batterijhuisvesting, battery husbandry, dierenwelzijn, animal welfare, batterijkooien, battery cages, pluimvee, poultry, hennen, hens, dierlijke productie, animal production, 603-C Huisvesting, management en verzorging van dieren, 603-C Animal Housing, Management and Care, 608-G Pluimvee, 608-G Poultry, Letter

URL: https://edepot.wur.nl/177229
https://edepot.wur.nl/177229