المؤلفون: Siseth Martínez-Caballero, Céline Freton, Rafael Molina, Sergio G. Bartual, Virginie Gueguen-Chaignon, Chryslène Mercy, Federico Gago, Kiran V. Mahasenan, Inés G. Muñoz, Mijoon Lee, Dusan Hesek, Shahriar Mobashery, Juan A. Hermoso, Christophe Grangeasse

المصدر: Cell Reports, Vol 42, Iss 7, Pp 112756- (2023)

مصطلحات موضوعية: CP: Microbiology, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723007672; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/d81c8fc5e2aa4f5d9ff7f86ec5f0dc25

المؤلفون: Choon Kim, Kiran V. Mahasenan, Atul Bhardwaj, Olaf Wiest, Mayland Chang, Shahriar Mobashery

المصدر: ACS Omega, Vol 6, Iss 30, Pp 19983-19994 (2021)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/7da29ff0ab894a20996c30c25f9d7507

المؤلفون: Siseth Martínez-Caballero, Kiran V. Mahasenan, Choon Kim, Rafael Molina, Rhona Feltzer, Mijoon Lee, Renee Bouley, Dusan Hesek, Jed F. Fisher, Inés G. Muñoz, Mayland Chang, Shahriar Mobashery, Juan A. Hermoso

المصدر: Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5392-5405 (2021)

مصطلحات موضوعية: Divisome, Staphylococcus aureus, X-ray crystal structure, SAXS in-solution structure, Molecular dynamics simulations, PBP1, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037021004037; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/0af59740be1241078a1417fa0b394874

المؤلفون: Martín Alcorlo, David A. Dik, Stefania De Benedetti, Kiran V. Mahasenan, Mijoon Lee, Teresa Domínguez-Gil, Dusan Hesek, Elena Lastochkin, Daniel López, Bill Boggess, Shahriar Mobashery, Juan A. Hermoso

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/120e67d6e4b84738995cb033a43e838a

المؤلفون: Choon Kim (6916526), Kiran V. Mahasenan (1336059), Atul Bhardwaj (2020060), Olaf Wiest (105849), Mayland Chang (475727), Shahriar Mobashery (475725)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Pharmacology, Evolutionary Biology, Immunology, Infectious Diseases, Plant Biology, Virology, Computational Biology, Astronomical and Space Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transmembrane regions, ARH domain, small-molecule binders, reading frames, coronavirus disease, low-micromolar binders, proteins optimized, PP 1a, polypeptide stretches, PP 1ab, Drug Discovery, Escherichia coli, ORF, NSP 3, template hits, genome encodes, anti-COVID -19 pharmaceuticals

Relation: https://figshare.com/articles/journal_contribution/Production_of_Proteins_of_the_SARS-CoV_2_Proteome_for_Drug_Discovery/15025040

الاتاحة: https://doi.org/10.1021/acsomega.1c02984.s001

المؤلفون: Atul Bhardwaj, Kiran V. Mahasenan, Choon Kim, Olaf Wiest, Mayland Chang, Shahriar Mobashery

المصدر: ACS Omega, Vol 6, Iss 30, Pp 19983-19994 (2021)
ACS Omega

مصطلحات موضوعية: Proteases, Drug discovery, Chemistry, General Chemical Engineering, General Chemistry, Computational biology, medicine.disease_cause, Genome, Transmembrane protein, Article, Open reading frame, Proteome, medicine, Gene, QD1-999, Coronavirus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714241b67153764f53133ee2de17e1e6
https://doaj.org/article/7da29ff0ab894a20996c30c25f9d7507

المؤلفون: Kiran V. Mahasenan, Jeshina Janardhanan, Sara Tejera, Elena Lastochkin, Shahriar Mobashery, Yuanyuan Qian, William R. Wolter, Giuseppe Allegretta, Zhihong Peng, Melissa Malia N. Gozun, Mayland Chang, Rhona Feltzer, Valerie A. Schroeder

المصدر: Journal of Medicinal Chemistry. 63:5287-5296

مصطلحات موضوعية: 0303 health sciences, biology, Chemistry, medicine.drug_class, Antibiotics, Allosteric regulation, In vitro toxicology, Active site, biochemical phenomena, metabolism, and nutrition, medicine.disease_cause, 01 natural sciences, 0104 chemical sciences, Microbiology, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Staphylococcus aureus, In vivo, Drug Discovery, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, Quinazolinone, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6291ab9052c87a4a8a8d6f64b0fe64be
https://doi.org/10.1021/acs.jmedchem.0c00153

المؤلفون: Kiran V. Mahasenan, Rhona Feltzer, Dusan Hesek, Mijoon Lee, Renee Bouley, Siseth Martínez-Caballero, Choon Kim, Jed F. Fisher, Shahriar Mobashery, Rafael Molina, Juan A. Hermoso, Inés G. Muñoz, Mayland Chang

المساهمون: National Institutes of Health (US), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), ALBA Synchrotron

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5392-5405 (2021)

مصطلحات موضوعية: Staphylococcus aureus, Penicillin binding proteins, PASTA domains, Antibiotics inhibition, SAXS in-solution structure, Biophysics, Peptidoglycan binding, Biochemistry, chemistry.chemical_compound, Structural Biology, Glycosyltransferase, Genetics, Divisome, ComputingMethodologies_COMPUTERGRAPHICS, biology, Molecular dynamics simulations, PBP1, X-ray crystal structure, PASTA domain, Computer Science Applications, Structural biology, chemistry, biology.protein, Penicillin Antibiotic, Peptidoglycan, Linker, TP248.13-248.65, Biotechnology, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa14893e10e00bda2814c5622751d7fd
http://hdl.handle.net/10261/256139

المؤلفون: Julia Sanz-Aparicio, Mijoon Lee, Kiran V. Mahasenan, María T. Batuecas, Shahriar Mobashery, Choon Kim, Juan A. Hermoso, Jed F. Fisher, Neha Rana, Stefania De Benedetti, Dusan Hesek

المساهمون: University of Notre Dame, Ministerio de Ciencia, Innovación y Universidades (España), ALBA Synchrotron, National Institutes of Health (US)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, 010405 organic chemistry, Stereochemistry, Pseudomonas aeruginosa, Mutant, Oxocarbenium, Biofilm, General Medicine, Periplasmic space, medicine.disease_cause, 01 natural sciences, Biochemistry, 0104 chemical sciences, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Catalytic cycle, medicine, Molecular Medicine, Glycoside hydrolase, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fb3588b071701ca8769f50964297a2
https://doi.org/10.1021/acschembio.9b00754

المؤلفون: Shahriar Mobashery, Kiran V. Mahasenan, Mayland Chang, Juan A. Hermoso

المساهمون: National Institutes of Health (US), Ministerio de Economía y Competitividad (España)

المصدر: Acc Chem Res
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Staphylococcus aureus, medicine.drug_class, medicine.medical_treatment, Allosteric regulation, Antibiotics, Cephalosporin, Biology, Molecular Dynamics Simulation, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Article, Microbiology, chemistry.chemical_compound, Adjuvants, Immunologic, Bacterial Proteins, Catalytic Domain, Drug Discovery, medicine, Penicillin-Binding Proteins, Quinazolinones, Bacteria, 010405 organic chemistry, Drug discovery, Pseudomonas aeruginosa, Glycopeptides, General Medicine, General Chemistry, 0104 chemical sciences, Anti-Bacterial Agents, chemistry, Peptidoglycan, Peptidoglycan Glycosyltransferase, Adjuvant, Allosteric Site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cc18732765b8952ad22dacaa684e3a
https://europepmc.org/articles/PMC8176569/

المؤلفون: Yuanyuan, Qian, Giuseppe, Allegretta, Jeshina, Janardhanan, Zhihong, Peng, Kiran V, Mahasenan, Elena, Lastochkin, Melissa Malia N, Gozun, Sara, Tejera, Valerie A, Schroeder, William R, Wolter, Rhona, Feltzer, Shahriar, Mobashery, Mayland, Chang

المصدر: J Med Chem

مصطلحات موضوعية: Mice, Mice, Inbred ICR, Staphylococcus aureus, Structure-Activity Relationship, Neutropenia, Animals, Female, Microbial Sensitivity Tests, biochemical phenomena, metabolism, and nutrition, Article, Anti-Bacterial Agents, Quinazolinones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::152bc927bf3a7db1e25ac82eece1fd30
https://pubmed.ncbi.nlm.nih.gov/32343145

المؤلفون: Mijoon Lee, Shahriar Mobashery, Elena Lastochkin, Kiran V. Mahasenan, Jed F. Fisher, María T. Batuecas, Juan A. Hermoso, David A. Dik, Daniel R. Marous

المساهمون: Ministerio de Economía y Competitividad (España)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Mutation, Missense, 010402 general chemistry, Cleavage (embryo), medicine.disease_cause, 01 natural sciences, Biochemistry, Catalysis, Bacterial cell structure, 03 medical and health sciences, Catalytic Domain, medicine, Escherichia coli, chemistry.chemical_classification, Escherichia coli K12, biology, Chemistry, Escherichia coli Proteins, Wild type, Glycosyltransferases, Active site, Lyase, 0104 chemical sciences, 030104 developmental biology, Enzyme, Amino Acid Substitution, Lytic cycle, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d96d30a0da0fdffbb70dfb1497b096
https://doi.org/10.1021/acs.biochem.8b00800

المؤلفون: Mayland Chang, Ming Gao, Trung T. Nguyen, Derong Ding, Mark A. Suckow, Valerie A. Schroeder, Shahriar Mobashery, William R. Wolter, Kiran V. Mahasenan

المصدر: ACS Medicinal Chemistry Letters. 9:708-713

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Metalloproteinase, Trifluoromethyl, Stereochemistry, Drug discovery, ADAM10, Organic Chemistry, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Enzyme, chemistry, Pharmacokinetics, 030220 oncology & carcinogenesis, Drug Discovery, Potency, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa00abb3c720ab1b20391127e04dcb6
https://doi.org/10.1021/acsmedchemlett.8b00163

المؤلفون: John Jacobs, Emma Frost, Mark A. Suckow, Shahriar Mobashery, Kiran V. Mahasenan, Derong Ding, William R. Wolter, Katerina Zorina-Lichtenwalter, Mayland Chang, Valerie A. Schroeder, Ming Gao, Maria Bastian

المصدر: ACS Medicinal Chemistry Letters. 8:654-659

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Benzoxazinones, In silico, Organic Chemistry, Context (language use), Matrix metalloproteinase, Biology, Biochemistry, Combinatorial chemistry, Small molecule, 03 medical and health sciences, Molecular dynamics, 030104 developmental biology, 0302 clinical medicine, Enzyme, chemistry, 030220 oncology & carcinogenesis, Drug Discovery, Biophysics, Enzyme kinetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8295158ed7f8b1d255d132612f7a5bc
https://doi.org/10.1021/acsmedchemlett.7b00130

المؤلفون: Renee Bouley, María T. Batuecas, Mayland Chang, Jed F. Fisher, Rafael Molina, Shahriar Mobashery, Kiran V. Mahasenan, Juan A. Hermoso

المساهمون: Ministerio de Economía y Competitividad (España)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Models, Molecular, 0301 basic medicine, Penicillin binding proteins, Protein Conformation, Stereochemistry, Allosteric regulation, Crystallography, X-Ray, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Biochemistry, Article, Catalysis, Cell wall, 03 medical and health sciences, chemistry.chemical_compound, Colloid and Surface Chemistry, Allosteric Regulation, Bacterial Proteins, Biosynthesis, medicine, Penicillin-Binding Proteins, chemistry.chemical_classification, Molecular Structure, biology, Active site, General Chemistry, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, Staphylococcus aureus, Biocatalysis, biology.protein, Thermodynamics, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad315d911cb80d53ececc9cc645283ff
https://doi.org/10.1021/jacs.6b12565

المؤلفون: Kiran V. Mahasenan, Valerie A. Schroeder, Haoqian Zhang, Alpa Trivedi, Mark A. Suckow, Shahriar Mobashery, William R. Wolter, Mayland Chang, Linda J. Noble-Haeusslein, Ming Gao

المصدر: ACS Chemical Neuroscience. 7:1482-1487

مصطلحات موضوعية: Male, 0301 basic medicine, Cord, Physiology, Cognitive Neuroscience, Drug Evaluation, Preclinical, Matrix Metalloproteinase Inhibitors, Motor Activity, Matrix metalloproteinase, Selective inhibition, Pharmacology, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Matrix Metalloproteinase 14, medicine, Animals, Sulfones, Spinal cord injury, Spinal Cord Injuries, Mice, Knockout, Molecular Structure, Chemistry, Phenyl Ethers, Recovery of Function, Cell Biology, General Medicine, Spinal cord, medicine.disease, Molecular Docking Simulation, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Matrix Metalloproteinase 9, Spinal Cord, Drug Design, Anesthesia, Matrix Metalloproteinase 2, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d69527efc04a6ed4191523784b84ba9
https://doi.org/10.1021/acschemneuro.6b00217

المؤلفون: Matthew M. Champion, Mark A. Suckow, Mijoon Lee, Shahriar Mobashery, William R. Wolter, Rocio L. Pérez, Mayland Chang, Valerie A. Schroeder, Elena Lastochkin, Charles E. Peterson, Dusan Hesek, Margaret K. Rose, Jeffrey I. Jones, Kiran V. Mahasenan, Derong Ding, Trung T. Nguyen

المصدر: Journal of medicinal chemistry. 61(19)

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Pharmacology, Matrix metalloproteinase, Matrix Metalloproteinase Inhibitors, Sulfides, Diabetes Mellitus, Experimental, 03 medical and health sciences, Methylamines, Mice, 0302 clinical medicine, Downregulation and upregulation, Becaplermin, Diabetes mellitus, Drug Discovery, medicine, Animals, Humans, Metalloproteinase, Wound Healing, Chemistry, Drug discovery, medicine.disease, Diabetic foot, Diabetic Foot, Mice, Inbred C57BL, 030104 developmental biology, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Wound healing, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d32d749a5acdfecbed5da9c9c20ef24
https://pubmed.ncbi.nlm.nih.gov/30212201

المؤلفون: Kiran V. Mahasenan, Isabel Usón, Mijoon Lee, Shahriar Mobashery, Juan A. Hermoso, Dusan Hesek, David A. Dik, Shusuke Tomoshige, Claudia Millán, Teresa Domínguez-Gil, María T. Batuecas, Elena Lastochkin

المساهمون: Agencia Estatal de Investigación (España), National Institutes of Health (US), Ministerio de Economía y Competitividad (España), University of Notre Dame, Ministerio de Economía, Industria y Competitividad (España)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Glycan, Peptidog, genetic structures, 010402 general chemistry, 01 natural sciences, Bacterial cell structure, Cell wall, 03 medical and health sciences, chemistry.chemical_compound, Lycanlytic transglycosylases, chemistry.chemical_classification, Cell-wall recycling, Multidisciplinary, biology, Active site, Glycosidic bond, Lyase, 0104 chemical sciences, 030104 developmental biology, Enzyme, Biochemistry, chemistry, biology.protein, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cddd902b5ad6ac1f28aacc5c8b64e32
http://hdl.handle.net/10261/174141

المؤلفون: Mijoon, Lee, María T, Batuecas, Shusuke, Tomoshige, Teresa, Domínguez-Gil, Kiran V, Mahasenan, David A, Dik, Dusan, Hesek, Claudia, Millán, Isabel, Usón, Elena, Lastochkin, Juan A, Hermoso, Shahriar, Mobashery

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(17)

مصطلحات موضوعية: Structure-Activity Relationship, Bacterial Proteins, Glycoside Hydrolases, Protein Domains, Pseudomonas aeruginosa, Peptidoglycan, Biological Sciences, Crystallography, X-Ray

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d23f2bc5d315a3186b2f6cf0f0bfae1b
https://pubmed.ncbi.nlm.nih.gov/29632171

المؤلفون: Daniel R. Marous, Malika Kumarasiri, Kiran V. Mahasenan, Juan A. Hermoso, Shahriar Mobashery, Jed F. Fisher, David A. Dik, Enrico Speri, Byungjin Byun

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Stereochemistry, lcsh:Medicine, Flagellum, 010402 general chemistry, Cleavage (embryo), medicine.disease_cause, 01 natural sciences, Article, Bacterial cell structure, Cell wall, 03 medical and health sciences, chemistry.chemical_compound, Cell Wall, Catalytic Domain, Escherichia coli, medicine, lcsh:Science, Type VI secretion system, Multidisciplinary, Escherichia coli Proteins, lcsh:R, Acetal, Glycosyltransferases, Type VI Secretion Systems, 3. Good health, 0104 chemical sciences, 030104 developmental biology, chemistry, Lytic cycle, lcsh:Q

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f772e864809e4a2f751ed688031b98a
https://doi.org/10.1038/s41598-018-22527-y