المؤلفون: Lee, Benjamin, Griffin, Shawn, Doh, Jean, Ciurea, Stefan, Jeyakumar, Deepa, Kongtim, Piyanuch, Naqvi, Kiran

مصطلحات موضوعية: Blast-phase CML, Chronic myeloid leukemia, Myeloid blast crisis, Tyrosine kinase inhibitor, “7 + 3” chemotherapy

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8ws8s27j
https://escholarship.org/content/qt8ws8s27j/qt8ws8s27j.pdf

المؤلفون: Lee, Benjamin, Liu, Jenny, Griffin, Shawn, Doh, Jean, Ciurea, Stefan, Kongtim, Piyanuch, Brem, Elizabeth

المصدر: Cancer Medicine. 13(19)

مصطلحات موضوعية: Bruton tyrosine kinase inhibitor, blastoid variant, mantle cell lymphoma, Humans, Lymphoma, Mantle-Cell, Male, Agammaglobulinaemia Tyrosine Kinase, Female, Protein Kinase Inhibitors, Aged, Middle Aged, Retrospective Studies, Antineoplastic Combined Chemotherapy Protocols, Aged, 80 and over, Adult, Treatment Outcome, Hematopoietic Stem Cell Transplantation, Salvage Therapy, Tumor Suppressor Protein p53, Tyrosine Kinase Inhibitors

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7r53x254
https://escholarship.org/content/qt7r53x254/qt7r53x254.pdf

المصدر: A Phase 1 Trial of the Combination of the Heat Shock Protein-90 (HSP90) Inhibitor Onalespib (AT13387) and the Cyclin-Dependent Kinase (CDK) Inhibitor AT7519M in Patients With Advanced Solid Tumors

المؤلفون: Dederer, Verena, Sanz Murillo, Marta, Karasmanis, Eva, Hatch, Kathryn, Chatterjee, Deep, Preuss, Franziska, Abdul Azeez, Kamal, Nguyen, Landon, Galicia, Christian, Dreier, Birgit, Plückthun, Andreas, Versees, Wim, Mathea, Sebastian, Leschziner, Andres, Reck-Peterson, Samara, Knapp, Stefan

المصدر: Journal of Biological Chemistry. 300(7)

مصطلحات موضوعية: DARPin, LRRK2, Parkinson’s disease, Rab8a, WD40, cryo-electron microscopy, kinase, kinase inhibitor, microtubule, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Humans, Ankyrin Repeat, Parkinson Disease, HEK293 Cells, rab GTP-Binding Proteins, Phosphorylation, Cryoelectron Microscopy, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/65h9j1ct
https://escholarship.org/content/qt65h9j1ct/qt65h9j1ct.pdf

المؤلفون: Lin, Lin, Zhao, Jingrong, Kubota, Naoto, Li, Zhelin, Lam, Yi-Li, Nguyen, Lauren P, Yang, Lu, Pokharel, Sheela P, Blue, Steven M, Yee, Brian A, Chen, Renee, Yeo, Gene W, Chen, Chun-Wei, Chen, Liang, Zheng, Sika

المصدر: Neuron. 112(13)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Genetics, Pediatric, Stem Cell Research, Congenital Structural Anomalies, Stem Cell Research - Nonembryonic - Non-Human, Rare Diseases, Stem Cell Research - Embryonic - Non-Human, Brain Disorders, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Neurological, Animals, Tumor Suppressor Protein p53, Mice, Brain, Mice, Knockout, Neural Stem Cells, Nonsense Mediated mRNA Decay, Epistasis, Genetic, Microcephaly, Cell Cycle, Cyclin-Dependent Kinase Inhibitor p21, RNA-Binding Proteins, EJC, PAX6, TBR2, Upf1, Upf3a, Upf3b, cell division, neurogenesis, p21, p53, progenitor cell competence, Psychology, Cognitive Sciences, Neurology & Neurosurgery, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9742k8ch
https://escholarship.org/content/qt9742k8ch/qt9742k8ch.pdf

المؤلفون: Du, Steven, Fu, Dan, A Bota, Daniela, Kong, Xiao-Tang

المصدر: CNS Oncology. 13(1)

مصطلحات موضوعية: Brutons tyrosine kinase inhibitor, diffuse large B-cell lymphoma, ibrutinib, primary CNS lymphoma, relapsed or refractory primary CNS lymphoma, whole-brain radiation therapy, Humans, Piperidines, Adenine, Female, Aged, Central Nervous System Neoplasms, Pyrazoles, Pyrimidines, Neoplasm Recurrence, Local, Salvage Therapy, Remission Induction, Lymphoma

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/84t2m1jg
https://escholarship.org/content/qt84t2m1jg/qt84t2m1jg.pdf

المؤلفون: Roeker, Lindsey E, Coombs, Catherine C, Shah, Nirav N, Jurczak, Wojciech, Woyach, Jennifer A, Cheah, Chan Y, Patel, Krish, Maddocks, Kami, Wang, Yucai, Zinzani, Pier Luigi, Munir, Talha, Koh, Youngil, Thompson, Meghan C, Muehlenbein, Catherine E, Wang, Chunxiao, Sizelove, Richard, Abhyankar, Sarang, Hasanabba, Safarulla, Tsai, Donald E, Eyre, Toby A, Wang, Michael

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Patient Safety, Infectious Diseases, Cancer, Clinical Trials and Supportive Activities, Rare Diseases, Hematology, Clinical Research, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, B-cell malignancies, Bruton tyrosine kinase inhibitor, Long-term safety, Toxicity, Cardiorespiratory Medicine and Haematology, Immunology, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3dx0s71c
https://escholarship.org/content/qt3dx0s71c/qt3dx0s71c.pdf

المؤلفون: García Román, Silvia

المساهمون: University/Department: Universitat Ramon Llull. IQS SE - Química Orgànica i Farmacèutica (2015 - )

Thesis Advisors: Borrell Bilbao, José Ignacio, Rosell Costa, Rafael

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: LUNG CANCER, PYRIDO[2,3- d]PYRIMIDINE, TYROSINE KINASE INHIBITOR, DDR2, G719S EGFR, KRAS, Ciències naturals, químiques, físiques i matemàtiques

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/401388

المؤلفون: Meagher, Margaret, Minervini, Andrea, Mir, Maria, Cerrato, Clara, Rebez, Giacomo, Autorino, Riccardo, Hampton, Lance, Campi, Riccardo, Kriegmair, Maximilian, Linares, Estefania, Hevia, Vital, Musquera, Maria, DAnna, Mauricio, Roussel, Eduard, Albersen, Maarten, Pavan, Nicola, Claps, Francesco, Antonelli, Alessandro, Marchioni, Michele, Paksoy, Nail, Erdem, Selcuk, Derweesh, Ithaar

مصطلحات موضوعية: Immunotherapy, Metastatic renal cell carcinoma, Nephrectomy, Survival, Tyrosine kinase inhibitor

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5wj3c1wm
https://escholarship.org/content/qt5wj3c1wm/qt5wj3c1wm.pdf

المؤلفون: Lee, Jin, Reyes, Nabora, Ravishankar, Supriya, Zhou, Minqi, Krasilnikov, Maria, Ringler, Christian, Pohan, Grace, Wilson, Chris, Ang, Kenny, Peng, Tien, Tsukui, Tatsuya, Sheppard, Dean, Arkin, Michelle, Wolters, Paul

المصدر: The Journal of Clinical Investigation. 134(9)

مصطلحات موضوعية: Aging, Cellular senescence, Drug screens, Fibrosis, Pulmonology, Animals, Cyclin-Dependent Kinase Inhibitor p16, Mice, Humans, Fibroblasts, Cellular Senescence, Idiopathic Pulmonary Fibrosis, Senotherapeutics, Male, Lung, Female, HSP90 Heat-Shock Proteins

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/94x7g6t7
https://escholarship.org/content/qt94x7g6t7/qt94x7g6t7.pdf

المؤلفون: Wang, Jichuan, Ferrena, Alexander, Zhang, Ranxin, Singh, Swapnil, Viscarret, Valentina, Al-Harden, Waleed, Aldahamsheh, Osama, Borjihan, Hasibagan, Singla, Amit, Yaguare, Simon, Tingling, Janet, Lo, Yungtai, Gorlick, Richard, Schwartz, Edward, Zhao, Hongling, Yang, Rui, Geller, David, Zheng, Deyou, Hoang, Bang, Zi, Xiaolin

المصدر: Oncogene. 43(13)

مصطلحات موضوعية: Animals, Humans, Mice, Bone Neoplasms, Carcinogenesis, Cyclin-Dependent Kinase Inhibitor p27, Mice, Knockout, Osteosarcoma, S-Phase Kinase-Associated Proteins, Tumor Microenvironment

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4kz2t6w6
https://escholarship.org/content/qt4kz2t6w6/qt4kz2t6w6.pdf

المؤلفون: Wirta, David, Li, Xiao-Yan, Shen, Wang, Lu, Caroline, Novack, Gary D, Group, VVN539-CS201 Study, Christie, William, Hartman, Paul J, Tafoya, Lawrence, Tekwani, Navin, Louis, St

المصدر: Ophthalmology Science. 4(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Ophthalmology and Optometry, Neurosciences, Clinical Research, Clinical Trials and Supportive Activities, Eye Disease and Disorders of Vision, Patient Safety, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Eye, VVN539-CS201 Study Group, Glaucoma, Intraocular pressure, Ocular hypertension, Rho-kinase inhibitor, VVN539

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4cj771xf

المؤلفون: Ya-Chun Huang, Nan-Yao Lee, Meng-Yu Weng

المصدر: Journal of Microbiology, Immunology and Infection, Vol 58, Iss 1, Pp 112-119 (2025)

مصطلحات موضوعية: Biologics, Janus kinase inhibitor, Pneumocystis jirovecii colonization, Rheumatoid arthritis, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1684118224001579; https://doaj.org/toc/1684-1182

URL الوصول: https://doaj.org/article/00f716d4ddf14f35bed1b071904852ab

المؤلفون: Daniel Isufi, BSc(Med), Mikkel Bak Jensen, MD, Nikolai Loft, MD, PhD, Lone Skov, MD, PhD, DMSc, Jesper Elberling, MD, PhD, Farzad Alinaghi, MD, PhD

المصدر: JAAD International, Vol 18, Iss , Pp 106-116 (2025)

مصطلحات موضوعية: immune-mediated diseases, infections, JAK inhibitors, Janus kinase inhibitor, randomized clinical trials, Dermatology, RL1-803

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266632872400169X; https://doaj.org/toc/2666-3287

URL الوصول: https://doaj.org/article/b7cfb694dc984328bc812dac7b138985

المؤلفون: Masato Kikuta, Sei Naito, Takahiro Osawa, Kazuyuki Numakura, Takafumi Narisawa, Yuki Takai, Mayu Yagi, Yuya Sekine, Ojiro Tokairin, Nobuo Shinohara, Tomonori Habuchi, Norihiko Tsuchiya

المصدر: BMC Cancer, Vol 25, Iss 1, Pp 1-12 (2025)

مصطلحات موضوعية: Comparison, Immunotherapy, Immune-combinations, Prognosis, Renal cell carcinoma, Tyrosine kinase inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/93e83d9a23c9462f89ca3d5c3755fa7d

المؤلفون: Peter Youssef, Sabina Ciciriello, Talib Tahir, Joanna Leadbetter, Belinda Butcher, Miriam Calao, Nicole Walsh, Catherine O’Sullivan, Tegan Smith, Geoffrey Littlejohn

المصدر: Rheumatology and Therapy, Vol 12, Iss 1, Pp 173-202 (2025)

مصطلحات موضوعية: Australia, Biologic disease-modifying antirheumatic drug (bDMARD), Janus kinase inhibitor (JAKi), Persistence, Real-world effectiveness, Remission, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-6576; https://doaj.org/toc/2198-6584

URL الوصول: https://doaj.org/article/a57c54c4b9674f7187f7a4755c3e2ff1

المؤلفون: Liu Y, Li X, Zhang M, Men Y, Wang Y, Zhu X, Zheng L

المصدر: Drug Design, Development and Therapy, Vol Volume 19, Pp 515-524 (2025)

مصطلحات موضوعية: ha121-28, food effects, pharmacokinetics, safety, tyrosine kinase inhibitor, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/effects-of-food-on-the-pharmacokinetics-and-safety-of-ha121-28-tablet--peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/d9452ef88bbf4e14a59ace3007981ab9

المؤلفون: Bacharach J, Sadri E, Sawhney G, Kopczynski C, Merchea MM

المصدر: Clinical Ophthalmology, Vol Volume 19, Pp 175-186 (2025)

مصطلحات موضوعية: glaucoma, intraocular pressure, prostaglandin analog, rho-kinase inhibitor, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: https://www.dovepress.com/effects-of-switching-to-netarsudillatanoprost-fixed-dose-combination-f-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483

URL الوصول: https://doaj.org/article/00589d1a34f14672a4ab0c005d7a820c

المؤلفون: Seung Hyun Park, Kyung Noh Yoon, Yang Xu, Myung Chan Gye

المصدر: The World Journal of Men's Health, Vol 43, Iss 1, Pp 174-187 (2025)

مصطلحات موضوعية: cyclin-dependent kinase inhibitor p57, leydig cells, mice, stem cells, testes, Medicine, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690

URL الوصول: https://doaj.org/article/42621e1527184901bbb1a9e1801a2ca8

المؤلفون: Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama

المصدر: Scientific Reports, Vol 15, Iss 1, Pp 1-19 (2025)

مصطلحات موضوعية: Graft-versus-host disease, Meibomian gland dysfunction, Janus kinase inhibitor, Delgocitinib, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a256eec9e033479881ef93518e08c279