المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

المصدر: PLoS ONE, Vol 18, Iss 11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681176/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/625ab18a16f6489b880dfdb27a965ac6

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Amino_acid_analysis_traces_for_VHH_heterodimer_Trx_E_AH3_AA6_E_sequential_Edman_degradation_of_sample_from_S2_Fig_/24641522

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s003
https://figshare.com/articles/journal_contribution/Amino_acid_analysis_traces_for_VHH_heterodimer_Trx_E_AH3_AA6_E_sequential_Edman_degradation_of_sample_from_S2_Fig_/24641522

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/LC_A_inhibition_assay_data_in_support_of_Fig_2_/24641516

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s001
https://figshare.com/articles/journal_contribution/LC_A_inhibition_assay_data_in_support_of_Fig_2_/24641516

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Edman_amino_terminal_amino_acid_sequences_of_the_VHH_heterodimer_Trx_E_AH3_AA6_E_in_support_of_Fig_3_/24641519

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s002
https://figshare.com/articles/journal_contribution/Edman_amino_terminal_amino_acid_sequences_of_the_VHH_heterodimer_Trx_E_AH3_AA6_E_in_support_of_Fig_3_/24641519

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/24641549

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s012
https://figshare.com/articles/journal_contribution/S1_Raw_images_-/24641549

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Enteric_proteases_similarly_cleave_a_VHH_dimer_varying_in_spacer_sequences_/24641537

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s008
https://figshare.com/articles/journal_contribution/Enteric_proteases_similarly_cleave_a_VHH_dimer_varying_in_spacer_sequences_/24641537

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Amino_acid_analysis_traces_for_VHH_heterodimer_6H_E_StxA5_Stx2G1_E_sequential_Edman_degradation_of_sample_from_S6_Fig_/24641534

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s007
https://figshare.com/articles/journal_contribution/Amino_acid_analysis_traces_for_VHH_heterodimer_6H_E_StxA5_Stx2G1_E_sequential_Edman_degradation_of_sample_from_S6_Fig_/24641534

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Edman_amino_terminal_amino_acid_sequence_of_the_VHH_heterodimer_6H_E_StxA5_Stx2G1_E_in_support_of_Fig_3_/24641531

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s006
https://figshare.com/articles/journal_contribution/Edman_amino_terminal_amino_acid_sequence_of_the_VHH_heterodimer_6H_E_StxA5_Stx2G1_E_in_support_of_Fig_3_/24641531

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/journal_contribution/Flanking_and_spacer_sequences_of_TcdB-neutralizing_VHH_heterodimer_from_Fig_7_/24641540

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s009
https://figshare.com/articles/journal_contribution/Flanking_and_spacer_sequences_of_TcdB-neutralizing_VHH_heterodimer_from_Fig_7_/24641540

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Characterization_of_sera_from_rabbits_immunized_with_a_VHH_pool_for_their_recognition_of_core_VHHs_/24641561

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g004
https://figshare.com/articles/figure/Characterization_of_sera_from_rabbits_immunized_with_a_VHH_pool_for_their_recognition_of_core_VHHs_/24641561

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/dataset/S1_Data_-/24641546

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.s011
https://figshare.com/articles/dataset/S1_Data_-/24641546

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Comparing_the_enteric_PK_of_conventional_antibodies_IgG1_and_IgA2_to_that_of_VHHs_/24641567

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g006
https://figshare.com/articles/figure/Comparing_the_enteric_PK_of_conventional_antibodies_IgG1_and_IgA2_to_that_of_VHHs_/24641567

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/VHH_heterohexamer_degradation_by_intestinal_proteases_/24641552

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g001
https://figshare.com/articles/figure/VHH_heterohexamer_degradation_by_intestinal_proteases_/24641552

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Intestinal_proteases_preferentially_degrade_epitope_tags_and_VHH_spacers_before_inactivating_VHH_function_/24641555

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g002
https://figshare.com/articles/figure/Intestinal_proteases_preferentially_degrade_epitope_tags_and_VHH_spacers_before_inactivating_VHH_function_/24641555

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Preferred_intestinal_protease_cleavage_sites_identified_in_multimeric_VHH_spacer_and_flanking_regions_/24641558

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g003
https://figshare.com/articles/figure/Preferred_intestinal_protease_cleavage_sites_identified_in_multimeric_VHH_spacer_and_flanking_regions_/24641558

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Comparing_i_in_vitro_i_vs_i_in_vivo_i_assays_of_VHH-agent_enteric_PK_/24641573

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g008
https://figshare.com/articles/figure/Comparing_i_in_vitro_i_vs_i_in_vivo_i_assays_of_VHH-agent_enteric_PK_/24641573

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Monomeric_VHHs_vary_widely_in_functional_stability_to_intestinal_proteases_/24641564

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g005
https://figshare.com/articles/figure/Monomeric_VHHs_vary_widely_in_functional_stability_to_intestinal_proteases_/24641564

المؤلفون: Michelle Debatis, Hillary Danz, Jacqueline M. Tremblay, Kimberly Gaspie, Raymond K. Kudej, Vladimir Vigdorovich, Noah Sather, Justyna J. Jaskiewicz, Saul Tzipori, Charles B. Shoemaker

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Physiology, Biotechnology, Ecology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, similar incubations performed, flexible spacers composed, also called nanobodies, enteric disease therapeutics, multimeric camelid vhh, gi tract proteases, div >< p, chyme incubations comparable, functional core vhhs, enteric vhh pk, enteric proteases, selected nanobodies, digestive tract, enteric use, yet little, widely variable, vivo <, vitro <, unstructured domains, thus indicating

Relation: https://figshare.com/articles/figure/Enteric_proteases_similarly_cleave_VHH_dimers_with_variable_flanking_sequence_and_spacer_length_/24641570

الاتاحة: https://doi.org/10.1371/journal.pone.0291937.g007
https://figshare.com/articles/figure/Enteric_proteases_similarly_cleave_VHH_dimers_with_variable_flanking_sequence_and_spacer_length_/24641570