يعرض 1 - 20 نتائج من 1,320 نتيجة بحث عن '"Khvorova, A"', وقت الاستعلام: 0.90s تنقيح النتائج
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    Academic Journal
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    Academic Journal

    المصدر: Alzheimers & Dementia: The Journal of the Alzheimers Association. 20(9)

    وصف الملف: application/pdf

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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal

    المصدر: Nature. 592(7853)

    وصف الملف: application/pdf

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    Academic Journal
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    Academic Journal

    المساهمون: Neurology, School of Medicine

    المصدر: PMC

    وصف الملف: application/pdf

    Relation: Alzheimer's & Dementia; https://hdl.handle.net/1805/44538

  15. 15
    Academic Journal

    المساهمون: Morningside Graduate School of Biomedical Sciences, Psychiatry, RNA Therapeutics Institute, Samuel Hildebrand, Julianna Buchwald

    المصدر: Alzheimer's & dementia : the journal of the Alzheimer's Association ; 20 ; 4 ; 2632 ; 2652 ; United States

    Relation: This article is based on a previously available preprint in bioRxiv, https://doi.org/10.1101/2022.06.28.498012.; Alzheimer’s & Dementia; https://doi.org/10.1002/alz.13703; Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 Apr;20(4):2632-2652. doi:10.1002/alz.13703. Epub 2024 Feb 20. PMID: 38375983; PMCID: PMC11032532.; http://hdl.handle.net/20.500.14038/53522; Alzheimer's & dementia : the journal of the Alzheimer's Association

  16. 16
    Academic Journal

    المساهمون: Morningside Graduate School of Biomedical Sciences, RNA Therapeutics Institute, Julianna E Buchwald, David A Cooper

    المصدر: Molecular therapy. Nucleic acids ; 34 ; 102080 ; United States

    Relation: Molecular Therapy Nucleic Acids; https://doi.org/10.1016/j.omtn.2023.102080; Fakih HH, Tang Q, Summers A, Shin M, Buchwald JE, Gagnon R, Hariharan VN, Echeverria D, Cooper DA, Watts JK, Khvorova A, Sleiman HF. Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity. Mol Ther Nucleic Acids. 2023 Nov 17;34:102080. doi:10.1016/j.omtn.2023.102080. PMID: 38089931; PMCID: PMC10711485.; http://hdl.handle.net/20.500.14038/53096; Molecular therapy. Nucleic acids

  17. 17
    Academic Journal

    المساهمون: Biochemistry and Molecular Biotechnology, Horae Gene Therapy Center, Li Weibo Institute for Rare Diseases Research, Microbiology and Physiological Systems, Molecular, Cell and Cancer Biology, Morningside Graduate School of Biomedical Sciences, NeuroNexus Institute, Program in Molecular Medicine, RNA Therapeutics Institute, Han Zhang, David A Cooper, Rebecca Panwala, Nicholas Gaston

    المصدر: Nucleic acids research ; 52 ; 2 ; 977 ; 997 ; United States ; England

    Relation: Nucleic Acids Research; https://doi.org/10.1093/nar/gkad1125; Zhang H, Kelly K, Lee J, Echeverria D, Cooper D, Panwala R, Amrani N, Chen Z, Gaston N, Wagh A, Newby GA, Xie J, Liu DR, Gao G, Wolfe SA, Khvorova A, Watts JK, Sontheimer EJ. Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo. Nucleic Acids Res. 2024 Jan 25;52(2):977-997. doi:10.1093/nar/gkad1125. PMID: 38033325; PMCID: PMC10810193.; http://hdl.handle.net/20.500.14038/53101

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    Academic Journal

    المساهمون: Morningside Graduate School of Biomedical Sciences, RNA Therapeutics Institute, David A Cooper

    المصدر: Journal of controlled release : official journal of the Controlled Release Society ; 349 ; 831 ; 843 ; United States ; Netherlands

    Relation: Journal of Controlled Release; https://doi.org/10.1016/j.jconrel.2022.07.041; Biscans A, Ly S, McHugh N, Cooper DA, Khvorova A. Engineered ionizable lipid siRNA conjugates enhance endosomal escape but induce toxicity in vivo. J Control Release. 2022 Sep;349:831-843. doi:10.1016/j.jconrel.2022.07.041. Epub 2022 Aug 3. PMID: 35917865; PMCID: PMC10281028.; http://hdl.handle.net/20.500.14038/52940; Journal of controlled release : official journal of the Controlled Release Society

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    Academic Journal

    المساهمون: Medicine, Psychiatry, RNA Therapeutics Institute

    المصدر: Nucleic acids research ; 52 ; 9 ; 5273 ; 5284 ; United States ; England

    Relation: Nucleic Acids Research; https://doi.org/10.1093/nar/gkae100; Ferguson CM, Godinho BMDC, Echeverria D, Hassler M, Vangjeli L, Sousa J, McHugh N, Alterman J, Hariharan V, Krishnamurthy PM, Watts J, Rogaev E, Khvorova A. A combinatorial approach for achieving CNS-selective RNAi. Nucleic Acids Res. 2024 May 22;52(9):5273-5284. doi:10.1093/nar/gkae100. PMID: 38348876; PMCID: PMC11109952.; http://hdl.handle.net/20.500.14038/53542

  20. 20
    Academic Journal

    المساهمون: Biochemistry and Molecular Biotechnology, Program in Molecular Medicine, RNA Therapeutics Institute

    المصدر: Nucleic acids research ; 52 ; 9 ; 4799 ; 4817 ; United States ; England

    Relation: Nucleic Acids Research; https://doi.org/10.1093/nar/gkae260; Sarli SL, Fakih HH, Kelly K, Devi G, Rembetsy-Brown JM, McEachern HR, Ferguson CM, Echeverria D, Lee J, Sousa J, Sleiman HF, Khvorova A, Watts JK. Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Nucleic Acids Res. 2024 May 22;52(9):4799-4817. doi:10.1093/nar/gkae260. PMID: 38613388; PMCID: PMC11109979.; http://hdl.handle.net/20.500.14038/53541