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1
المؤلفون: Jessica Harper Calderon, Yasalp Jimenez, Hock E, Zhe Li, Marisa Carbonaro, Kevin Barringer, Gavin Thurston, Courtney M. Williams, Christopher Daly, Maria del Pilar Molina-Portela
المصدر: The FASEB Journal. 35
مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, Amino Acid Motifs, Cholesterol 7 alpha-hydroxylase, Fibroblast growth factor, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 4, Cholesterol 7-alpha-Hydroxylase, Molecular Biology, Cell Proliferation, Activator (genetics), Chemistry, FGF15, FGF19, Liver regeneration, Cell biology, Fibroblast Growth Factors, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Hepatocyte, Mutation, Hepatocytes, Female, Protein Multimerization, Thrombospondins, 030217 neurology & neurosurgery, Signal Transduction, Biotechnology
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2
المؤلفون: Axel Knebel, Charline Peng, Brian Werneburg, Xiang Li, Scott Jakes, Kevin Barringer, Jun Li, Lian Wang, Nick A. Morrice
المصدر: Journal of Biochemistry. 141:353-362
مصطلحات موضوعية: Thymus Gland, Protein Serine-Threonine Kinases, Biology, Biochemistry, Substrate Specificity, MAP2K7, Proto-Oncogene Proteins c-pim-1, Proto-Oncogene Proteins, hemic and lymphatic diseases, Consensus Sequence, Animals, Humans, Amino Acid Sequence, Eukaryotic Initiation Factors, Kinase activity, Molecular Biology, Peptide sequence, MAPK14, MAP kinase kinase kinase, Kinase, Cyclin-dependent kinase 2, General Medicine, Rats, biology.protein, Cyclin-dependent kinase 9, Apoptosis Regulatory Proteins
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3
المؤلفون: Peter M. Grob, Janice R. Brickwood, Cheng-Kon Shih, Maryann Hoermann, Julian Adams, Racheline Schwartz, Daniel Pauletti, Eva David, David A. Erickson, Kevin Barringer, Charles L. Cywin, David Joseph, Susan E. Hattox, Janice M. Klunder, Christopher L. Sorge
المصدر: Journal of Medicinal Chemistry. 41:2960-2971
مصطلحات موضوعية: Nevirapine, Pyridines, Mutant, In Vitro Techniques, Antiviral Agents, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Potency, Cell Line, Transformed, chemistry.chemical_classification, biology, Chemistry, Wild type, Drug Resistance, Microbial, Azepines, Nucleotidyltransferase, Virology, HIV Reverse Transcriptase, Reverse transcriptase, Enzyme, Amino Acid Substitution, Enzyme inhibitor, Mutation, HIV-1, Microsomes, Liver, biology.protein, Reverse Transcriptase Inhibitors, Molecular Medicine, medicine.drug
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4Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase
المؤلفون: Andre White, Bennett T. Farmer, Anthony Kronkaitis, Lian Wang, Eugene R. Hickey, Charline Peng, Joey Studts, Jun Li, Kevin Barringer, Sheenah Mische, Kevin Chungeng Qian
المصدر: The Journal of biological chemistry. 280(7)
مصطلحات موضوعية: Models, Molecular, Protein Folding, Protein Conformation, Adenylyl Imidodiphosphate, Biology, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Biochemistry, MAP2K7, Serine, Structure-Activity Relationship, Protein structure, Proto-Oncogene Proteins c-pim-1, hemic and lymphatic diseases, Catalytic Domain, Proto-Oncogene Proteins, Humans, Amino Acid Sequence, Molecular Biology, Peptide sequence, MAPK14, Serine/threonine-specific protein kinase, Kinase, Cell Biology, Enzyme Activation, Apoproteins, Protein Binding
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5
المؤلفون: Kevin Barringer, Roger R. LaFrance, Kevin Chungeng Qian, Sheenah Mische, Bennett T. Farmer, Alistair Baptiste, Joey Studts, Lian Wang, Charline Peng, Anthony Kronkaitis
المصدر: Acta crystallographica. Section F, Structural biology and crystallization communications. 61(Pt 1)
مصطلحات موضوعية: Protein Conformation, Restriction Mapping, Biophysics, Biology, medicine.disease_cause, Crystallography, X-Ray, Transfection, Biochemistry, MAP2K7, Serine, Apoenzymes, Proto-Oncogene Proteins c-pim-1, Structural Biology, hemic and lymphatic diseases, Genetics, medicine, Humans, c-Raf, Threonine, Cloning, Molecular, Escherichia coli, DNA Primers, Serine/threonine-specific protein kinase, Base Sequence, Kinase, Condensed Matter Physics, Recombinant Proteins, Crystallography, Crystallization Communications, Signal transduction, Crystallization