المؤلفون: John J. Kelly, Dale Tranter, Els Pardon, Gamma Chi, Holger Kramer, Lotta Happonen, Kelly M. Knee, Jay M. Janz, Jan Steyaert, Christine Bulawa, Ville O. Paavilainen, Juha T. Huiskonen, Wyatt W. Yue

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Biosciences, Molecular and Integrative Biosciences Research Programme, Department of Bio-engineering Sciences, Structural Biology Brussels

المصدر: Nature Structural & Molecular Biology. 29:420-429

مصطلحات موضوعية: MECHANISM, PROTEIN, EUKARYOTIC CHAPERONIN, ATP HYDROLYSIS, CYTOSOLIC CHAPERONIN, GROUP-II CHAPERONIN, Structural Biology, SUBUNIT, CRYO-EM STRUCTURE, 1182 Biochemistry, cell and molecular biology, CRYSTAL-STRUCTURE, sense organs, CCT CHAPERONIN, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c6ef58fbb341764a444fd4085970ed
https://doi.org/10.1038/s41594-022-00755-1

المؤلفون: Ariamala Gopalsamy, Ann E. Aulabaugh, Amey Barakat, Kevin C. Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro-Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Choi, Robert L. Dow, Olugbeminiyi O. Fadeyi, Xidong Feng, Scott P. France, Roger M. Howard, Jay M. Janz, Jayasankar Jasti, Reema Jasuja, Lyn H. Jones, Amanda King-Ahmad, Kelly M. Knee, Jeffrey T. Kohrt, Chris Limberakis, Spiros Liras, Carlos A. Martinez, Kim F. McClure, Arjun Narayanan, Jatin Narula, Jonathan J. Novak, Thomas N. O’Connell, Mihir D. Parikh, David W. Piotrowski, Olga Plotnikova, Ralph P. Robinson, Parag V. Sahasrabudhe, Raman Sharma, Benjamin A. Thuma, Dipy Vasa, Liuqing Wei, A. Zane Wenzel, Jane M. Withka, Jun Xiao, Hatice G. Yayla

المصدر: Journal of Medicinal Chemistry. 64:326-342

مصطلحات موضوعية: Hemolytic anemia, Erythrocytes, Chemistry, Point mutation, Hemoglobin, Sickle, Cell, Genetic disorder, Phases of clinical research, Hemoglobin A, Anemia, Sickle Cell, Disease, Pharmacology, Multiple dose, medicine.disease, Oxygen, Mice, medicine.anatomical_structure, Drug Discovery, Quinolines, medicine, Animals, Molecular Medicine, Hemoglobin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fb3aa72d831f7f375af97473787b3a
https://doi.org/10.1021/acs.jmedchem.0c01518

المؤلفون: Jay M. Janz, David W. Piotrowski, Dharani Rao, Christine Bulawa, Zane Wenzel, Kevin Beaumont, Phil Jeffrey, Jonathan J. Novak, Jayasankar Jasti, Amey Barakat, John E. Murphy, Kelly M. Knee, Reema Jasuja

المصدر: American Journal of Hematology

مصطلحات موضوعية: business.industry, Anemia, Non covalent, Cell, Hematology, Disease, Anemia, Sickle Cell, medicine.disease, Disease Models, Animal, Hemoglobins, Mice, medicine.anatomical_structure, Text mining, Correspondence, Cancer research, Medicine, Animals, Hemoglobin, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8de2e0e1d3f56e872b775998d02a634
https://pubmed.ncbi.nlm.nih.gov/33891711

المؤلفون: Kelly Jj, Els Pardon, Tranter D, Christine Bulawa, Jay M. Janz, Jan Steyaert, Wyatt W. Yue, Kelly M. Knee, Chi G, Holger Kramer, Juha T. Huiskonen, Ville O. Paavilainen

مصطلحات موضوعية: 0303 health sciences, biology, Chemistry, Chaperonin, Folding (chemistry), 03 medical and health sciences, Cytosol, 0302 clinical medicine, Tubulin, Proteome, biology.protein, Biophysics, Protein folding, sense organs, Cytoskeleton, 030217 neurology & neurosurgery, Actin, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dd73f17a77d4601fa00994e8ee235499
https://doi.org/10.1101/2021.03.26.436673

المؤلفون: John J, Kelly, Dale, Tranter, Els, Pardon, Gamma, Chi, Holger, Kramer, Lotta, Happonen, Kelly M, Knee, Jay M, Janz, Jan, Steyaert, Christine, Bulawa, Ville O, Paavilainen, Juha T, Huiskonen, Wyatt W, Yue

المصدر: Nature structuralmolecular biology. 29(5)

مصطلحات موضوعية: Male, Protein Folding, Chaperonins, Tubulin, Humans, Peptides, Actins, Chaperonin Containing TCP-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a3f1a29810face2c95b478b4c1937b85
https://pubmed.ncbi.nlm.nih.gov/35449234

المؤلفون: Kelly M. Knee, Surjit B. Dixit, Y Colin Echeverría Aitken, Sergei Ponomarev, Y D. L. Beveridge, Ishita Mukerji

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dbeveridge.blogs.wesleyan.edu/outgoing/dbeveridge.blogs.wesleyan.edu/files/2011/07/Biophys-J-95-257-Spectro-and-Molec-Dyn-Evidence-for-a-Sequential.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.306.8180; http://dbeveridge.blogs.wesleyan.edu/outgoing/dbeveridge.blogs.wesleyan.edu/files/2011/07/Biophys-J-95-257-Spectro-and-Molec-Dyn-Evidence-for-a-Sequential.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.306.8180
http://dbeveridge.blogs.wesleyan.edu/outgoing/dbeveridge.blogs.wesleyan.edu/files/2011/07/Biophys-J-95-257-Spectro-and-Molec-Dyn-Evidence-for-a-Sequential.pdf

المؤلفون: Betty Pettersen, Lila Ramaiah, Nathanael G. Lintner, Kelly M. Knee, S. Denise Field, Reema Jasuja, Youngwook Ahn, Lindsay Tomlinson, Amey Barakat, Brendon Kapinos, Zane Wenzel

المصدر: Blood. 136:27-28

مصطلحات موضوعية: Hemolytic anemia, medicine.anatomical_structure, business.industry, Immunology, Cell, Medicine, Cell Biology, Hematology, Disease, business, medicine.disease, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::95d6b76f28888a18ef8f33b9c6205ac3
https://doi.org/10.1182/blood-2020-142052

المؤلفون: Jingkun Yang, Oksana A. Sergeeva, Kelly M. Knee, Jonathan King

المصدر: Protein Science. 23:693-702

مصطلحات موضوعية: Methanococcus, education.field_of_study, Population, Biology, biology.organism_classification, Biochemistry, Chaperonin, Lens protein, Crystallin, Chaperone (protein), Native state, biology.protein, Biophysics, Protein folding, education, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f6f3bb565ddd340b4f08dd933a06fe7d
https://doi.org/10.1002/pro.2452

المؤلفون: Kevin Beaumont, Dharani Rao, Amey Barakat, David W. Piotrowski, Jay Jasti, Parag Sahasrabudhe, Jeanne S. Chang, Jay M. Janz, Zane Wenzel, Reema Jasuja, Kelly M. Knee, Jatin Narula

المصدر: Blood. 134:207-207

مصطلحات موضوعية: Hemolytic anemia, medicine.diagnostic_test, Anemia, Chemistry, Immunology, Cell, Cell Biology, Hematology, Hypoxia (medical), Hematocrit, medicine.disease, Biochemistry, Sickle cell anemia, medicine.anatomical_structure, medicine, Cancer research, Hemoglobin, medicine.symptom, Vaso-occlusive crisis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9dc927dd85912e349487260c05c84d5b
https://doi.org/10.1182/blood-2019-128270

المؤلفون: Oksana A. Sergeeva, Kelly M. Knee, Jonathan King

المصدر: Cell Stress and Chaperones. 18:137-144

مصطلحات موضوعية: Original Paper, biology, Protein subunit, Cell Biology, biology.organism_classification, Biochemistry, Protein Refolding, Chaperonin, Cell biology, HeLa, Protein Subunits, Crystallin, Chaperone (protein), Heat shock protein, biology.protein, Humans, HSP70 Heat-Shock Proteins, Luciferase, Protein folding, HSP90 Heat-Shock Proteins, gamma-Crystallins, sense organs, Chaperonin Containing TCP-1, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf72b52abb7e50e43f0de54330ed052f
https://doi.org/10.1007/s12192-012-0357-z

المؤلفون: Jonathan King, Daniel R. Goulet, Kelly M. Knee

المصدر: Experimental Eye Research. 93:371-381

مصطلحات موضوعية: Protein Denaturation, Protein Folding, Chemistry, Mutant, Sodium Citrate, Small molecule, Cataract, Article, Sensory Systems, Ion, Lens protein, Cellular and Molecular Neuroscience, Ophthalmology, chemistry.chemical_compound, Spectrometry, Fluorescence, Biochemistry, Crystallin, Lens, Crystalline, Sodium citrate, Unfolded protein response, Humans, Protein folding, Citrates, gamma-Crystallins, Protein Unfolding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d4407d97d6d985e5477f41a6fd48d
https://doi.org/10.1016/j.exer.2011.04.011

المؤلفون: Bo Chen, Jonathan King, Daniel R. Goulet, Kelly M. Knee, Wah Chiu, Junjie Zhang

المصدر: Protein Science. 20:30-41

مصطلحات موضوعية: Protein subunit, macromolecular substances, Plasma protein binding, Biology, Biochemistry, GroEL, Chaperonin, enzymes and coenzymes (carbohydrates), Crystallin, Chaperone (protein), Biophysics, biology.protein, Native state, Protein folding, sense organs, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::893ca6c61201e6173c5de0a19a7ebaab
https://doi.org/10.1002/pro.531

المؤلفون: Kelly M. Knee, Jonathan King, Oksana A. Sergeeva

المصدر: Biophysical Journal. 108(2)

مصطلحات موضوعية: education.field_of_study, Chemistry, Mutant, Population, Biophysics, Group II Chaperonins, Chaperonin, Lens protein, Crystallography, Domain interface, Side chain, Native state, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a7c7591c5e11674795971c6a1cd351

المؤلفون: Oksana A, Sergeeva, Jingkun, Yang, Jonathan A, King, Kelly M, Knee

المصدر: Protein science : a publication of the Protein Society. 23(6)

مصطلحات موضوعية: Protein Folding, Archaeal Proteins, Methanococcus, Group II Chaperonins, Humans, gamma-Crystallins, Articles, Protein Structure, Secondary, Protein Binding, Protein Structure, Tertiary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::fecfd0afec3b09b0e291436be70c99bd
https://pubmed.ncbi.nlm.nih.gov/24615724

المؤلفون: Reema Jasuja, Pratap Singh, Kelly M. Knee, Joseph C. Nneji, John J. Kelly, Amey Barakat, Jay M. Janz

المصدر: Blood. 128:3644-3644

مصطلحات موضوعية: Hemolytic anemia, medicine.medical_specialty, Hematology, Mean corpuscular hemoglobin concentration, medicine.diagnostic_test, business.industry, Immunology, Soluble cell adhesion molecules, Inflammation, Cell Biology, Pharmacology, medicine.disease, Biochemistry, Hemolysis, In vivo, Internal medicine, Medicine, Hemoglobin, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::342d69f8ee72e8bbde19e6697296d331
https://doi.org/10.1182/blood.v128.22.3644.3644

المؤلفون: Jose H, Pereira, Corie Y, Ralston, Nicholai R, Douglas, Ramya, Kumar, Tom, Lopez, Ryan P, McAndrew, Kelly M, Knee, Jonathan A, King, Judith, Frydman, Paul D, Adams

المصدر: The EMBO journal. 31(3)

مصطلحات موضوعية: Adenosine Triphosphatases, Models, Molecular, Binding Sites, Adenine Nucleotides, Protein Conformation, Hydrolysis, Group II Chaperonins, macromolecular substances, Crystallography, X-Ray, Article, enzymes and coenzymes (carbohydrates), Kinetics, biological sciences, bacteria, Amino Acid Sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7c6224ebb1cc7eb05ad7e11f9f759fa1
https://pubmed.ncbi.nlm.nih.gov/22193720

المؤلفون: Ishita Mukerji, Sabina Wang, C. Alvin Head, Pedro Montero-Huerta, Hemant S. Thatte, Tohru Ikuta, Jay X. Tang, Kelly M. Knee, Ratan Mani Joshi, Kenneth R. Bridges

المصدر: Archives of biochemistry and biophysics. 510(1)

مصطلحات موضوعية: P50, Erythrocytes, Hemoglobin, Sickle, Biophysics, chemistry.chemical_element, Anemia, Sickle Cell, Nitric Oxide, Biochemistry, Oxygen, Methemoglobin, Article, Nitric oxide, Polymerization, chemistry.chemical_compound, Antisickling Agents, Humans, Molecular Biology, Deoxygenation, Depolymerization, Viscosity, virus diseases, digestive system diseases, Isoelectric point, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209e8feaac4a5bb818f6ed84bbef1f77
https://pubmed.ncbi.nlm.nih.gov/21457702

المؤلفون: Kelly M, Knee, Daniel R, Goulet, Junjie, Zhang, Bo, Chen, Wah, Chiu, Jonathan A, King

المصدر: Protein science : a publication of the Protein Society. 20(1)

مصطلحات موضوعية: enzymes and coenzymes (carbohydrates), Adenosine Triphosphate, Bacterial Proteins, Methanococcus, Group II Chaperonins, Humans, macromolecular substances, sense organs, gamma-Crystallins, Protein Refolding, Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dfc8781ea83b371fbfa26afe44aadc5a
https://pubmed.ncbi.nlm.nih.gov/20981710

المؤلفون: Corie Y. Ralston, Jose Henrique Pereira, Daniel W. Meyer, Daniel R. Goulet, Paul D. Adams, Nicholai R. Douglas, Jonathan King, Kelly M. Knee, Judith Frydman

مصطلحات موضوعية: Models, Molecular, Protein Folding, Protein subunit, Methanococcus, Group II Chaperonins, Crystal structure, macromolecular substances, Crystallography, X-Ray, Biochemistry, Chaperonin, Adenosine Triphosphate, Group I Chaperonins, Molecular Biology, biology, Hydrolysis, Methanococcus maripaludis, Cell Biology, biology.organism_classification, Acceptor, Protein Structure, Tertiary, Crystallography, enzymes and coenzymes (carbohydrates), Chaperone (protein), biological sciences, Protein Structure and Folding, biology.protein, bacteria, Protein folding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1457340c8d92288f1064563c25c65b
https://europepmc.org/articles/PMC2934662/

المؤلفون: Jonathan King, Kelly M. Knee, Daniel R. Goulet, Kate L. Moreau

المصدر: The FASEB Journal. 24

مصطلحات موضوعية: Chemistry, Crystallin, Group ii, Mutant, Genetics, Molecular Biology, Biochemistry, Molecular biology, Biotechnology, Chaperonin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f3a3f4a2f268e4f2a416dd08bd0322c9
https://doi.org/10.1096/fasebj.24.1_supplement.834.3