المؤلفون: Holly Jackson, Judith Anzures-Cabrera, Kirsten I. Taylor, Gennaro Pagano, PASADENA Investigators, Prasinezumab Study Group, Claudia Altendorf, Chareyna Anandan, Giulia Andrews, Solène Ansquer, Raphaele Arrouasse, Sana Aslam, Jean-Philippe Azulay, Jeanette Baker, Ernest Balaguer Martinez, Shadi Barbu, Kara Bardram, Danny Bega, Helena Bejr-Kasem Marco, Isabelle Benatru, Eve Benchetrit, Felix Bernhard, Amir Besharat, Sagari Bette, Amelie Bichon, Andrew Billnitzer, Sophie Blondeau, Thomas Boraud, Freiderike Borngräber, James Boyd, Kathrin Brockmann, Matthew Brodsky, Ethan Brown, Christof Bruecke, Fabienne Calvas, Monica Canelo, Federico Carbone, Claire Carroll, Laura Casado Fernandez, Catherine Cassé-Perrot, Anna Castrioto, Helene Catala, Justine Chan, Samia Cheriet, Anthony Ciabarra, Joseph Classen, Juliana Coleman, Robert Coleman, Yaroslau Compta, Anne-Gaëlle Corbillé, Jean-Christophe Corvol, Mariana Cosgaya, Nabila Dahodwala, Philippe Damier, Elodie David, Thomas Davis, Marissa Dean, Berengere Debilly, Janell DeGiorgio, Andres Deik, Laure Delaby, Marie-Helene Delfini, Pascal Derkinderen, Philipp Derost, Maria de Toledo, Lisa Deuel, Ann Marie Diaz-Hernandez, Cameron Dietiker, Karina Dimenshteyn, Julio Dotor, Franck Durif, Jens Ebentheuer, Karla Maria Eggert, Sara Eichau Madueño, Claudia Eickhoff, Aaron Ellenbogen, Philipp Ellmerer, Ines Esparragosa Vazquez, Alexandre Eusebio, Siobhan Ewert, John Fang, Danielle Feigenbaum, Frederique Fluchere, Alexandra Foubert-Samier, Marie Fournier, Anne Fradet, Valerie Fraix, Samuel Frank, Franca Fries, Monique Galitzky, Marisol Gallardó Pérez, Jose Manuel García Moreno, Carmen Gasca, Thomas Gasser, Joyce Gibbons, Caroline Giordana, Alicia Gonzalez Martinez, Ira Goodman, Arantza Gorospe, Marie Goubeaud, David Grabli, Mangone Graziella, Stephan Grimaldi, Jeffrey Gross, Raquel Guimaraes-Costa, Andreas Hartmann, Christian Hartmann, Travis Hassell, Robert Hauser, Antonio Hernandez, Jorge Hernandez-Vara, Guenter Hoeglinger, Christian Homedes, Andrea Horta-Barba, Jean-Luc Houeto, Julius Huebl, Jennifer Hui, Stuart Isaacson, Joseph Jankovic, Annette Janzen, Junior Jauregui, Jocelyne Jiao, Maria Jose Marti Domenech, Xavier Joseph, Srinath Kadimi, Pat Kaminski, Silja Kannenberg, Jan Kassubek, Maya Katz, Kevin Klos, Shannon Klos, Christopher Kobet, Jennifer Koebert, Patricia Krause, Andrea Kuehn, Jaime Kulisevsky Bojarsky, Rajeev Kumar, Martin Kunz, Lille Kurvits, Kimberly Kwei, Simon Laganiere, Brice Laurens, Johannes Levin, Oren Levy, Peter LeWitt, Gurutz Linazasoro Cristóbal, Irene Litvan, Karlo Lizarraga, Katherine Longardner, Rocio Lopez, Lydia Lopez Manzanares, Sara Lucas del Pozo, Maria Rosario Luquin Puido, Nijee Luthra, Kelly Lyons, Sylvia Maass, Gerrit Machetanz, Yolanda Macias, David Maltete, Jorge Uriel Manez Miro, Louise-Laure Mariani, Juan Marin, Kathrin Marini, Ana Marques, Gloria Marti, Saul Martinez, Wassilios Meissner, Sara Meoni, Brit Mollenhauer, Dunia Mon Martinez, Johnson Moon, Elena Moro, Peter Morrison, Christoph Muehlberg, Manpreet Multani, Christine Murphy, Anthony Nicholas, Rajesh Pahwa, Antonio Palasi, Heidi Pape, Neepa Patel, Prity Patel, Marina Peball, Elizabeth Peckham, Terry Peery, Rafael Perez, Jesus Perez, Alisa Petit, Elmar Pinkhardt, Werner Poewe, Elsa Pomies, Cecile Preterre, Joseph Quinn, Olivier Rascol, Philippe Remy, Irene Richard, Benjamin Roeben, Emily Ruether, Jost-Julian Rumpf, David Russell, Hayet Salhi, Daniela Samaniego-Toro, Alexandra Samier-Foubert, Antonio Sanchez, Emmanuelle Schmitt, Alfons Schnitzler, Oliver Schorr, Julie Schwartzbard, Kerstin Schweyer, Klaus Seppi, Victoria Sergo, Holly Shill, Andrew Siderowf, Tanya Simuni, Umberto Spampinato, Ashok Sriram, Natividad Stover, Caroline Tanner, Arjun Tarakad, Carolyn Taylor, Claire Thalamus, Thomas Toothaker, Nadege Van Blercom, Nora Vanegas-Arrogave, Lydia Vela, Sylvian Vergnet, Tiphaine Vidal, Jonathan Vöglein, Ryan Walsh, Cheryl Waters, Mirko Wegscheider, Endy Weidinger, Caroline Weill, Gregor Wenzel, Tatiana Witjas, Isabel Wurster, Brenton Wright, Milan Zimmermann, Rafael Zuzuarregui, Markus Abt, Atieh Bamdadian, Teresa Barata, Nicholas Barbet, Sara Belli, Frank Boess, Azad Bonni, Edilio Borroni, Anne Boulay, Markus Britschgi, Jerome Chague, Valerie Cosson, Christian Czech, Dennis Deptula, Cheikh Diack, Rachelle Doody, Juergen Dukart, Giulia D’Urso, Sebastian Dziadek, Hannah Eddleston, Chris Edgar, Laurent Essioux, Morgan Farell, Rebecca Finch, Paulo Fontoura, Waltraud Gruenbauer, Andrea Hahn, Stefan Holiga, Michael Honer, Shirin Jadidi, Kelly Johnson-Wood, Markus Keller, Timothy Kilchenmann, Martin Koller, Thomas Kremer, Thomas Kustermann, Claire Landsdall, Michael Lindemann, Florian Lipsmeier, Cecile Luzy, Marianne Manchester, Maddalena Marchesi, Ferenc Martenyi, Meret Martin-Facklam, Katerina Mironova, Annabelle Monnet, Emma Moore, Daniel K Ness, Markus Niggli, Tania Nikolcheva, Susanne Ostrowitzki GP, Benedicte Passmard, Agnes Poirier, Anke Post, Megana Prasad, Nathalie Pross, Tiffany Quock, Benedicte Ricci, Ellen Rose, Christoph Sarry, Christine Schubert, Dennis Selkoe, Jeff Sevigny, Kaycee Sink, Hannah Staunton, Tim Steven, Alexander Strasak, Hanno Svoboda KT, Radhika Tripuraneni, Dylan Trundell, Daniel Umbricht, Lynne Verselis, Annamarie Vogt, Ekaterina Volkova-Volkmar, Cornelia Weber, Silke Weber, Wagner Zago

المصدر: Frontiers in Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: PASADENA, PPMI (Parkinson’s Progression Markers Initiative), Parkinson’s disease, progression predictors, ridge regression, disease stage, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.765765/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/053f64fffcf24c75a54f51f0e4c78787

المؤلفون: Gennaro Pagano, Frank G. Boess, Kirsten I. Taylor, Benedicte Ricci, Brit Mollenhauer, Werner Poewe, Anne Boulay, Judith Anzures-Cabrera, Annamarie Vogt, Maddalena Marchesi, Anke Post, Tania Nikolcheva, Gene G. Kinney, Wagner M. Zago, Daniel K. Ness, Hanno Svoboda, Markus Britschgi, Susanne Ostrowitzki, Tanya Simuni, Kenneth Marek, Martin Koller, Jeff Sevigny, Rachelle Doody, Paulo Fontoura, Daniel Umbricht, Azad Bonni, PASADENA Investigators, Prasinezumab Study Group, Claudia Altendorf, Chareyna Anandan, Giulia Andrews, Solène Ansquer, Raphaele Arrouasse, Sana Aslam, Jean-Philippe Azulay, Jeanette Baker, Ernest Balaguer Martinez, Shadi Barbu, Kara Bardram, Danny Bega, Helena Bejr-Kasem Marco, Isabelle Benatru, Eve Benchetrit, Felix Bernhard, Amir Besharat, Sagari Bette, Amelie Bichon, Andrew Billnitzer, Sophie Blondeau, Thomas Boraud, Freiderike Borngräber, James Boyd, Kathrin Brockmann, Matthew Brodsky, Ethan Brown, Christof Bruecke, Fabienne Calvas, Monica Canelo, Federico Carbone, Claire Carroll, Laura Casado Fernandez, Catherine Cassé-Perrot, Anna Castrioto, Helene Catala, Justine Chan, Samia Cheriet, Anthony Ciabarra, Joseph Classen, Juliana Coleman, Robert Coleman, Yaroslau Compta, Anne-Gaëlle Corbillé, Jean-Christophe Corvol, Mariana Cosgaya, Nabila Dahodwala, Philippe Damier, Elodie David, Thomas Davis, Marissa Dean, Berengere Debilly, Janell DeGiorgio, Andres Deik, Laure Delaby, Marie-Helene Delfini, Pascal Derkinderen, Philipp Derost, Maria de Toledo, Lisa Deuel, Ann Marie Diaz-Hernandez, Cameron Dietiker, Karina Dimenshteyn, Julio Dotor, Franck Durif, Jens Ebentheuer, Karla Maria Eggert, Sara Eichau Madueño, Claudia Eickhoff, Aaron Ellenbogen, Philipp Ellmerer, Ines Esparragosa Vazquez, Alexandre Eusebio, Siobhan Ewert, John Fang, Danielle Feigenbaum, Frederique Fluchere, Alexandra Foubert-Samier, Marie Fournier, Anne Fradet, Valerie Fraix, Samuel Frank, Franca Fries, Monique Galitzky, Marisol Gallardó Pérez, Jose Manuel García Moreno, Carmen Gasca, Thomas Gasser, Joyce Gibbons, Caroline Giordana, Alicia Gonzalez Martinez, Ira Goodman, Arantza Gorospe, Marie Goubeaud, David Grabli, Mangone Graziella, Stephan Grimaldi, Jeffrey Gross, Raquel Guimaraes-Costa, Andreas Hartmann, Christian Hartmann, Travis Hassell, Robert Hauser, Antonio Hernandez, Jorge Hernandez-Vara, Günter Höglinger, Christian Homedes, Andrea Horta-Barba, Jean-Luc Houeto, Julius Huebl, Jennifer Hui, Stuart Isaacson, Joseph Jankovic, Annette Janzen, Junior Jauregui, Jocelyne Jiao, Maria Jose Marti Domenech, Xavier Joseph, Srinath Kadimi, Pat Kaminski, Silja Kannenberg, Jan Kassubek, Maya Katz, Kevin Klos, Shannon Klos, Christopher Kobet, Jennifer Koebert, Patricia Krause, Andrea Kuehn, Jaime Kulisevsky Bojarsky, Rajeev Kumar, Martin Kunz, Lille Kurvits, Kimberly Kwei, Simon Laganiere, Brice Laurens, Johannes Levin, Oren Levy, Peter LeWitt, Gurutz Linazasoro Cristóbal, Irene Litvan, Karlo Lizarraga, Katherine Longardner, Rocio Lopez, Lydia Lopez Manzanares, Sara Lucas del Pozo, Maria Rosario Luquin Puido, Nijee Luthra, Kelly Lyons, Sylvia Maass, Gerrit Machetanz, Yolanda Macias, David Maltete, Jorge Uriel Manez Miro, Louise-Laure Mariani, Juan Marin, Kathrin Marini, Ana Marques, Gloria Marti, Saul Martinez, Wassilios Meissner, Sara Meoni, Dunia Mon Martinez, Johnson Moon, Elena Moro, Peter Morrison, Christoph Muehlberg, Manpreet Multani, Christine Murphy, Anthony Nicholas, Rajesh Pahwa, Antonio Palasi, Heidi Pape, Neepa Patel, Prity Patel, Marina Peball, Elizabeth Peckham, Terry Peery, Rafael Perez, Jesus Perez, Alisa Petit, Elmar Pinkhardt, Elsa Pomies, Cecile Preterre, Joseph Quinn, Olivier Rascol, Philippe Remy, Irene Richard, Benjamin Roeben, Emily Ruether, Jost-Julian Rumpf, David Russell, Hayet Salhi, Daniela Samaniego-Toro, Alexandra Samier-Foubert, Antonio Sanchez, Emmanuelle Schmitt, Alfons Schnitzler, Oliver Schorr, Julie Schwartzbard, Kerstin Schweyer, Klaus Seppi, Victoria Sergo, Holly Shill, Andrew Siderowf, Umberto Spampinato, Ashok Sriram, Natividad Stover, Caroline Tanner, Arjun Tarakad, Carolyn Taylor, Claire Thalamus, Thomas Toothaker, Nadege Van Blercom, Nora Vanegas-Arrogave, Lydia Vela, Sylvian Vergnet, Tiphaine Vidal, Jonathan Vöglein, Ryan Walsh, Cheryl Waters, Mirko Wegscheider, Endy Weidinger, Caroline Weill, Gregor Wenzel, Tatiana Witjas, Isabel Wurster, Brenton Wright, Milan Zimmermann, Rafael Zuzuarregui, Markus Abt, Atieh Bamdadian, Teresa Barata, Nicholas Barbet, Sara Belli, Frank Boess, Edilio Borroni, Jerome Chague, Valerie Cosson, Christian Czech, Dennis Deptula, Cheikh Diack, Juergen Dukart, Giulia D'Urso, Sebastian Dziadek, Hannah Eddleston, Chris Edgar, Laurent Essioux, Morgan Farell, Rebecca Finch, Waltraud Gruenbauer, Andrea Hahn, Stefan Holiga, Michael Honer, Shirin Jadidi, Kelly Johnson-Wood, Markus Keller, Timothy Kilchenmann, Thomas Kremer, Thomas Kustermann, Claire Landsdall, Michael Lindemann, Florian Lipsmeier, Cecile Luzy, Marianne Manchester, Ferenc Martenyi, Meret Martin-Facklam, Katerina Mironova, Annabelle Monnet, Emma Moore, Daniel K Ness, Markus Niggli, Benedicte Passmard, Agnes Poirier, Megana Prasad, Nathalie Pross, Tiffany Quock, Ellen Rose, Christoph Sarry, Christine Schubert, Dennis Selkoe, Kaycee Sink, Hannah Staunton, Tim Steven, Alexander Strasak, Kirsten Taylor, Radhika Tripuraneni, Dylan Trundell, Lynne Verselis, Ekaterina Volkova-Volkmar, Cornelia Weber, Silke Weber, Wagner Zago

المصدر: Frontiers in Neurology, Vol 12 (2021)

مصطلحات موضوعية: Parkinson's disease, alpha-synuclein (α-syn), prasinezumab, monoclonal antibodies, disease progression, MDS-UPDRS = Movement Disorder Society—Unified Parkinson's Disease Rating Scale, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2021.705407/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/a1132dd1342e45bda3945621de12e3fd

المؤلفون: Michael K. Lee, Schenk Dale B, Peter Seubert, Hadar Feinberg, Robin Barbour, Kelly Johnson-Wood, Menelas N. Pangalos, Amita Goel, Irene Griswold-Prenner, Linnea Diep, William I. Weis, Jingzhi Li, Davinder Gill, John P. Anderson, J. Steven Jacobsen, Thomas A. Comery, Donald Walker, Nicolas Piot, Guriqbal S. Basi, Angela Widom, Anthony Partridge, Jeanne Baker, Farshid Oshidari, Katerina Grantcharova

المصدر: Journal of Biological Chemistry. 285:3417-3427

مصطلحات موضوعية: Male, Genetically modified mouse, Heterozygote, medicine.medical_treatment, Molecular Conformation, Crystallography, X-Ray, Biochemistry, Epitopes, Mice, Immune system, Alzheimer Disease, In vivo, medicine, Animals, Humans, Molecular Biology, Amyloid beta-Peptides, Behavior, Animal, Linear epitope, biology, Cell Biology, Immunotherapy, medicine.disease, Recombinant Proteins, In vitro, Disease Models, Animal, Kinetics, Cross-Linking Reagents, Protein Structure and Folding, Immunology, biology.protein, Alzheimer's disease, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c127e58115c08c9d0fd96b9cce7c07
https://doi.org/10.1074/jbc.m109.045187

المؤلفون: Elizabeth F. Brigham, Karen S. Chen, Stephen B. Freedman, Ruth Motter, Weiqun Liu, Manuel Buttini, John P. Anderson, Lisa McConlogue, Sukanto Sinha, Kelly Johnson-Wood, Dora Games, Michael K. Lee, Michelle Zeller

المصدر: Journal of Biological Chemistry. 282:26326-26334

مصطلحات موضوعية: Genetically modified mouse, Aging, medicine.medical_specialty, Amyloid beta, Synaptic Membranes, Biochemistry, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, Internal medicine, mental disorders, Neurites, medicine, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, Molecular Biology, Gene, Gene knockout, Mice, Knockout, chemistry.chemical_classification, biology, Cell Biology, medicine.disease, Enzyme assay, Enzyme Activation, Disease Models, Animal, Enzyme, Endocrinology, chemistry, Immunology, biology.protein, Amyloid Precursor Protein Secretases, Alzheimer's disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3db05cead87c83caac2caa1064e167
https://doi.org/10.1074/jbc.m611687200

المؤلفون: Sue G. Griffith, Frederique Bard, Michael K. Lee, Kang Hu, Peter Seubert, Kelly Johnson-Wood, Celeste Lee, Ronald Black, Dale Schenk

المصدر: Annals of Neurology. 58:430-435

مصطلحات موضوعية: Amyloid, Blotting, Western, BACE1-AS, Dose-Response Relationship, Immunologic, Epitope, Epitopes, Alzheimer Disease, Antibody Specificity, Meningoencephalitis, Amyloid precursor protein, Humans, Medicine, Senile plaques, Amyloid beta-Peptides, biology, business.industry, P3 peptide, medicine.disease, Immunohistochemistry, Molecular biology, Peptide Fragments, Biochemistry of Alzheimer's disease, Neurology, Immunology, biology.protein, Immunization, Neurology (clinical), Alzheimer's disease, business, Epitope Mapping

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbc01a9c54e517b4b6781f9a4f7fe8b
https://doi.org/10.1002/ana.20592

المؤلفون: P. Seubert, Kathleen Hoenow, Dora Games, Teresa Guido, Vasquez Nicki J, Ted Yednock, Michael K. Lee, Dora Kholodenko, Catherine Cannon, Robin Barbour, Michael Fox, Kang Hu, Robert Carretto, Minh Nguyen, Ruth Motter, Pearl Tang, Dale Schenk, Celeste Lee, Frederique Bard, Kelly Johnson-Wood, Amanda Reed, Karen Khan

المصدر: Proceedings of the National Academy of Sciences. 100:2023-2028

مصطلحات موضوعية: medicine.drug_class, Molecular Sequence Data, Monoclonal antibody, Epitope, Epitopes, Alzheimer Disease, Antibody Specificity, Amyloid precursor protein, medicine, Humans, Amino Acid Sequence, Amyloid beta-Peptides, Multidisciplinary, biology, P3 peptide, Antibodies, Monoclonal, Biological Sciences, Molecular biology, Isotype, Peptide Fragments, Complement system, Epitope mapping, Immunology, biology.protein, Antibody, Epitope Mapping

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546e4278e4417ccb13a8b57592f18668
https://doi.org/10.1073/pnas.0436286100

المؤلفون: Ismail Kola, Weiqun Liu, Kjell A. Svensson, Mary E. Shuck, Hartmut Tintrup, Sarah Wright, John A. Wijsman, Karen S. Chen, Lisa McConlogue, Thomas T. Kawabe, John P. Anderson, Kang Hu, Guriqbal Basi, Michael Power, Steven L. Roberds, Karl Kappenman, Dale Schenk, Stephen B. Freedman, Michael Schoor, Normand Frigon, David W. Robertson, Ralf Kuehn, Dora Kate Games, Sukanto Sinha, George Shopp, Kelly Johnson-Wood, Nanette F. Nichols, Michael Jerome Bienkowski, Mike Lee, Gwen Tatsuno, Ruth Motter, Daniel G. Branstetter

المصدر: Human Molecular Genetics. 10:1317-1324

مصطلحات موضوعية: Male, medicine.medical_specialty, Ratón, medicine.disease_cause, Cell Line, Amyloid beta-Protein Precursor, Mice, Degenerative disease, Alzheimer Disease, Culture Techniques, Internal medicine, Endopeptidases, mental disorders, Genetics, medicine, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, Genetics (clinical), Mice, Knockout, Mutation, Amyloid beta-Peptides, biology, Brain, General Medicine, medicine.disease, Phenotype, Mice, Inbred C57BL, Endocrinology, Knockout mouse, Mice, Inbred CBA, biology.protein, Female, Amyloid Precursor Protein Secretases, Alzheimer's disease, Amyloid precursor protein secretase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62941ba2369e7d9bf17cea82323484d
https://doi.org/10.1093/hmg/10.12.1317

المؤلفون: Gui-Qiu Yu, Gwen Tatsuno, Kelly Johnson-Wood, Lennart Mucke, Lisa McConlogue, Margaret Mallory, Dora Kholodenko, Kang Hu, Eliezer Masliah, Edward Rockenstein

المصدر: The Journal of Neuroscience. 20:4050-4058

مصطلحات موضوعية: Genetically modified mouse, Aging, Transgene, medicine.medical_treatment, Molecular Sequence Data, Mice, Transgenic, Plaque, Amyloid, Biology, Receptors, Presynaptic, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, medicine, Animals, Humans, Amino Acid Sequence, RNA, Messenger, ARTICLE, Cognitive decline, Receptor, Peptide sequence, Amyloid beta-Peptides, General Neuroscience, Growth factor, Neurodegeneration, Wild type, medicine.disease, Peptide Fragments, Cell biology, Nerve Degeneration, Synapses, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a91a80896086054b05d7fdcf05c1e6
https://doi.org/10.1523/jneurosci.20-11-04050.2000

المؤلفون: Carol Lin, Eliezer Masliah, Tony Wyss-Coray, Margaret Mallory, Kelly Johnson-Wood, Lennart Mucke, Lisa McConlogue

المصدر: Nature. 389:603-606

مصطلحات موضوعية: Genetically modified mouse, Aging, medicine.medical_treatment, Central nervous system, BACE1-AS, Mice, Transgenic, Biology, Mice, Alzheimer Disease, Transforming Growth Factor beta, medicine, Animals, Humans, Benzothiazoles, Aged, Mice, Inbred BALB C, Amyloid beta-Peptides, Multidisciplinary, Neurodegeneration, Brain, Amyloidosis, medicine.disease, Cerebral Amyloid Angiopathy, Thiazoles, medicine.anatomical_structure, Cytokine, Astrocytes, Cancer research, Cerebral amyloid angiopathy, Alzheimer's disease, Blood vessel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93fe0bf89ace8e7f3391c1cc1cad744
https://doi.org/10.1038/39321

المؤلفون: Robin Barbour, Kelly Johnson-Wood, Dora Games, H. Tan, Dale Schenk, Lisa McConlogue, Michael K. Lee, Kang Hu, P. Seubert, G. Gordon, Ruth Motter, I. Lieberburg, Karen Khan, M. Gordon

المصدر: Proceedings of the National Academy of Sciences. 94:1550-1555

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, Amyloid, Transgene, Hippocampus, Mice, Transgenic, Biology, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, Internal medicine, mental disorders, medicine, Amyloid precursor protein, Animals, Humans, Inbreeding, Tissue Distribution, Crosses, Genetic, Amyloid beta-Peptides, Multidisciplinary, Amyloidosis, Age Factors, P3 peptide, Brain, Biological Sciences, medicine.disease, Immunohistochemistry, Disease Models, Animal, Endocrinology, Mutation, Immunology, biology.protein, Alzheimer's disease, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abc89061b819a1db9caf7e715e4dba4
https://doi.org/10.1073/pnas.94.4.1550

المؤلفون: Weiming Xia, Ivan Lieberburg, Peter St. George Hyslop, Dale Schenk, G. Levesque, Thekla S. Diehl, Peter Seubert, Dennis J. Selkoe, Paul E. Fraser, Billie J. Perry, Dora Kholodenko, Kelly Johnson-Wood, Robert Strome, Johanna M. Rommens, Soyeon Kim, Hong Yao, Angela Davis, Ruth Motter, Martin Citron, R. Sherrington, George A. Carlson, David Westaway, Michael K. Lee

المصدر: Nature Medicine. 3:67-72

مصطلحات موضوعية: Genetically modified mouse, Amyloid, Genetic Vectors, Mutant, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Biology, Transfection, medicine.disease_cause, Hippocampus, General Biochemistry, Genetics and Molecular Biology, Presenilin, Cell Line, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, Presenilin-2, mental disorders, Presenilin-1, medicine, Animals, Humans, APH-1, Mutation, Amyloid beta-Peptides, Wild type, Brain, Membrane Proteins, General Medicine, medicine.disease, Molecular biology, Peptide Fragments, Alzheimer's disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dffe9085e8ba40c54689e072591e9d
https://doi.org/10.1038/nm0197-67

المؤلفون: Thomas Donaldson, J. C. Clemens, Michael Power, Dale Schenk, Michael K. Lee, Robin Barbour, Lisa McConlogue, Frances Gillespie, James Vitale, Ferdie Soriano, Eliezer Masliah, Karen Khan, Lennart Mucke, Dora Games, Sam Wadsworth, Patricia Borthelette, Ree Alessandrini, Sheila P. Little, Jun Zhao, Ivan Lieberburg, Hua Tan, Elizabeth Penniman, Paul Leibowitz, Tony Carr, Peter Seubert, Stephanie Hagopian, Martin Montoya-Zavala, Ben Wolozin, Kelly Johnson-Wood, Ben W. Snyder, Catherine Blackwell, Terry Guido, Lisa Paganini, David S. Adams

المصدر: Nature. 373:523-527

مصطلحات موضوعية: Amyloid, Molecular Sequence Data, BACE1-AS, Mice, Transgenic, Immunoenzyme Techniques, Amyloid beta-Protein Precursor, Mice, chemistry.chemical_compound, Alzheimer Disease, mental disorders, Amyloid precursor protein, medicine, Animals, Humans, Senile plaques, DNA Primers, Platelet-Derived Growth Factor, Amyloid beta-Peptides, Microscopy, Confocal, Multidisciplinary, Base Sequence, biology, P3 peptide, Brain, medicine.disease, Biochemistry of Alzheimer's disease, Cell biology, chemistry, Mutation, biology.protein, Thioflavin, Alzheimer's disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5005c9bdf0ac9e05ed925c25c6442603
https://doi.org/10.1038/373523a0

المؤلفون: Lawrence C. Fritz, William J. Burke, Kelly Johnson-Wood, Pamela J. Ward, Sonia Braa, Robin Barbour, Dale Schenk, Hyung D. Chung, Kari J. Reinikainen, Thomas Henriksson, Paavo Riekkinen

المصدر: Journal of Neurochemistry. 56:1037-1042

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Amyloid, medicine.drug_class, medicine.medical_treatment, Enzyme-Linked Immunosorbent Assay, Disease, Monoclonal antibody, Biochemistry, Amyloid beta-Protein Precursor, Cellular and Molecular Neuroscience, Degenerative disease, Cerebrospinal fluid, Alzheimer Disease, Reference Values, mental disorders, medicine, Humans, Protein Precursors, Amyloid beta-Peptides, Protease, medicine.diagnostic_test, Chemistry, Antibodies, Monoclonal, medicine.disease, Immunoassay, Alzheimer's disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dbdf430d81022345049648a7ea47d6
https://doi.org/10.1111/j.1471-4159.1991.tb02026.x

المؤلفون: Dora Games, Menelas N. Pangalos, Pearl Tang, Gill Davinder, Kristin Kling, Ruth Motter, Sally Schroeter, Peter Seubert, J. Steven Jacobsen, Dale Schenk, Kelly Johnson-Wood, Robin Barbour, Dora Kholodenko, Guriqbal S. Basi, Karen Khan

المصدر: Neuro-degenerative diseases. 5(2)

مصطلحات موضوعية: Amyloid pathology, Pathology, medicine.medical_specialty, medicine.medical_treatment, Transgene, Peptide, Mice, Transgenic, Plaque, Amyloid, Antibodies, Mice, In vivo, medicine, Animals, chemistry.chemical_classification, Cerebral Cortex, Amyloid beta-Peptides, biology, Capture antibody, Amyloidosis, Immunotherapy, medicine.disease, Neurology, chemistry, Solubility, biology.protein, Cancer research, Female, Neurology (clinical), Antibody, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53486ddd39f117999f01960727cccd34
https://pubmed.ncbi.nlm.nih.gov/18182780

المؤلفون: Henry Grajeda, Manuel Buttini, Peter Seubert, Karen Khan, Eliezer Masliah, Robin Barbour, Ruth Motter, Stephen B. Freedman, Dale Schenk, Dora Games, Kelly Johnson-Wood

مصطلحات موضوعية: Amyloid, Synaptophysin, Hippocampus, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Neuropathology, Mice, Alzheimer Disease, Neurobiology of Disease, medicine, Animals, Cognitive decline, Cerebral Cortex, Neocortex, Amyloid beta-Peptides, biology, General Neuroscience, Neurodegeneration, P3 peptide, Age Factors, medicine.disease, Immunohistochemistry, Disease Models, Animal, medicine.anatomical_structure, Nerve Degeneration, Synapses, biology.protein, Immunotherapy, Peptides, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5cbed101445582a771a4040de61bcd
https://europepmc.org/articles/PMC6725749/

المؤلفون: Vasquez Nicki J, Kelly Johnson-Wood, Robin Barbour, Peter Seubert, Siobhán McClean, Minh Tan Nguyen, Dale Schenk, David J. Brayden, Deirdra Ahern, Jiping Huang, Ruth Motter, Louise Templeton

المصدر: Vaccine. 19(30)

مصطلحات موضوعية: Nervous system, Amyloid, Ratón, medicine.medical_treatment, Dose-Response Relationship, Immunologic, Pharmacology, Serum antibody, Antibodies, Mice, mental disorders, medicine, Animals, Particle Size, Saline, Polyglactin 910, Amyloid beta-Peptides, General Veterinary, General Immunology and Microbiology, biology, business.industry, Public Health, Environmental and Occupational Health, medicine.disease, Microspheres, Dose–response relationship, Infectious Diseases, medicine.anatomical_structure, Biodegradation, Environmental, Immunology, biology.protein, Molecular Medicine, Immunization, Alzheimer's disease, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceeb932ba55ee202beeaea2aee7056c
https://pubmed.ncbi.nlm.nih.gov/11457544

المؤلفون: Nancy G. Wehner, Dora Games, Kelly Johnson-Wood, Terry Guido, Karen Khan, Ferdie Soriano, Nicki Vasquez, Dale B. Schenk, Peter A. Seubert, Frederique Bard, Henry Grajeda, Ted Yednock

المصدر: Annals of the New York Academy of Sciences. 920

مصطلحات موضوعية: Genetically modified mouse, Pathology, medicine.medical_specialty, Mice, Transgenic, Hippocampus, General Biochemistry, Genetics and Molecular Biology, Mice, History and Philosophy of Science, Alzheimer Disease, medicine, Neurites, Animals, Humans, Gliosis, Overproduction, Pathological, Early onset, Amyloid beta-Peptides, Chemistry, General Neuroscience, Amyloidosis, Brain, medicine.disease, Peptide Fragments, Amyloid deposition, Immunization, Astrocytes, Immunology, Antibody Formation, Astrocytosis, Immunotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddf74c697aee96ccc8d3bcf788981da
https://pubmed.ncbi.nlm.nih.gov/11193164

المؤلفون: Jiping Huang, Catherine Cannon, Kelly Johnson-Wood, Kang Hu, Peter Seubert, Karen Khan, Ted Yednock, Dale Schenk, Teresa Guido, Henry Grajeda, Ivan Lieberburg, Rae Lyn Burke, Ruth Motter, Robin Barbour, Minh Nguyen, Michael K. Lee, Vasquez Nicki J, Dora Games, Frederique Bard, Brent Welch, Dora Kholodenko, Ferdie Soriano, Kim Weiss

المصدر: Nature medicine. 6(8)

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Amyloid beta, BACE1-AS, Mice, Transgenic, Plaque, Amyloid, In Vitro Techniques, General Biochemistry, Genetics and Molecular Biology, Antibodies, Mice, Phagocytosis, Alzheimer Disease, mental disorders, medicine, Amyloid precursor protein, Animals, Humans, Senile plaques, Amyloid beta-Peptides, biology, P3 peptide, General Medicine, medicine.disease, Biochemistry of Alzheimer's disease, Disease Models, Animal, Immunology, Crenezumab, biology.protein, Immunization, Alzheimer's disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1291d5410fd2f29c76ba71ebd80c6c83
https://pubmed.ncbi.nlm.nih.gov/10932230

المؤلفون: Teresa Guido, Dale Schenk, Mark Wogulis, Ferdie Soriano, Henry Grajeda, Dora Games, Kang Hu, Zhenmei Liao, Christopher Vandevert, Peter Seubert, Vasquez Nicki J, Jiping Huang, Shannan Walker, Linda Mutter, Dora Kholodenko, Michael K. Lee, Ted Yednock, Robin Barbour, George Shopp, Ivan Lieberburg, Karen Khan, Whitney Dunn, Kelly Johnson-Wood, Grace Gordon, Ruth Motter

المصدر: Nature. 400(6740)

مصطلحات موضوعية: Amyloid beta, BACE1-AS, Freund's Adjuvant, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Neuropathology, Buffers, Hippocampus, Presenilin, Mice, Alzheimer Disease, mental disorders, medicine, Amyloid precursor protein, Neurites, Animals, Humans, Point Mutation, Multidisciplinary, Amyloid beta-Peptides, biology, Vaccination, Brain, medicine.disease, Peptide Fragments, Serum Amyloid P-Component, Astrocytes, Immunology, Crenezumab, biology.protein, Alzheimer's disease, Gantenerumab, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2638d3ba5934ac909ddb6e72fd3e1ef
https://pubmed.ncbi.nlm.nih.gov/11961526

المؤلفون: Peter Seubert, R. Wolfert, Kelly Johnson-Wood, R. Motter, Linda Chang, Dale Schenk, D. Olson, C. Clark, Carmen Vigo-Pelfrey, Bruce L. Miller, Doug R. Galasko, P. Southwick, Robin Barbour, B. Munroe, Robert C. Green, Dora Kholodenko, Ivan Lieberburg

المصدر: Annals of neurology. 38(4)

مصطلحات موضوعية: Apolipoprotein E, Male, medicine.medical_specialty, Amyloid, Genotype, Molecular Sequence Data, Enzyme-Linked Immunosorbent Assay, tau Proteins, Central nervous system disease, Degenerative disease, Cerebrospinal fluid, Apolipoproteins E, Alzheimer Disease, Internal medicine, medicine, Humans, Amino Acid Sequence, Beta (finance), Aged, Amyloid beta-Peptides, business.industry, Middle Aged, medicine.disease, Peptide Fragments, Endocrinology, Neurology, Female, Neurology (clinical), Alzheimer's disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a84caba706cf9e37279384a8e3ecb6
https://pubmed.ncbi.nlm.nih.gov/7574461