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1
المؤلفون: Nitin Joshi, Jinfang Li, Kelly A Regal, J Brad Phipps, Raymond S. Sinatra
المصدر: Expert Opinion on Drug Metabolism & Toxicology. 11:481-489
مصطلحات موضوعية: Adult, Male, medicine.medical_treatment, Cmax, Bioequivalence, Pharmacology, Administration, Cutaneous, Toxicology, Systemic circulation, Fentanyl, Pharmacokinetics, Humans, Medicine, Prospective Studies, Transdermal, Iontophoresis, business.industry, Patient-controlled analgesia, General Medicine, Analgesics, Opioid, Therapeutic Equivalency, Area Under Curve, Anesthesia, Female, business, Half-Life, medicine.drug
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2
المصدر: Chemical Research in Toxicology. 19:279-287
مصطلحات موضوعية: chemistry.chemical_classification, Chromatography, biology, Chemistry, Electrospray ionization, Active site, Peptide, General Medicine, Metabolism, Glutathione, Toxicology, Mass spectrometry, Amino acid, chemistry.chemical_compound, Enzyme, Biochemistry, polycyclic compounds, biology.protein
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3
المؤلفون: Garold S. Yost, Kelly A. Regal, Cai Yuan, George M. Laws, Gary L. Skiles
المصدر: Chemical Research in Toxicology. 14:1014-1024
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Nucleophilic addition, Chemistry, Stereochemistry, Reactive intermediate, Spectrometry, Mass, Secondary Ion, Dado, Nucleosides, General Medicine, Toxicology, Rats, Skatole, Adduct, DNA Adducts, chemistry.chemical_compound, Liver, Microsomes, Carcinogens, Animals, Amine gas treating, Ion trap, Methylene, Nucleoside
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4
المؤلفون: Sidney D. Nelson, Kelly A. Regal
المصدر: Archives of Biochemistry and Biophysics. 384:47-58
مصطلحات موضوعية: Binding Sites, Magnetic Resonance Spectroscopy, Dose-Response Relationship, Drug, biology, Stereochemistry, Iron, Biophysics, Spin–lattice relaxation, Active site, Biochemistry, Dissociation constant, Crystallography, chemistry.chemical_compound, chemistry, Cytochrome P-450 CYP1A2, Caffeine, biology.protein, Humans, Molecular Biology, Heme, Paraxanthine, Demethylation, Methyl group
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5
المؤلفون: Mohamoud M. Abdi, Nabil Hussain Al-Humadi, Mayssa Attar, Theodore J. Baird, Jeff Behrens, Nathan Boersen, Jacqueline A. Brassard, Melissa J. Beck, Jennifer G. Brown, Edward W. Carney, Ting-Tung A. Chang, Mingli Chen, Dorothy B. Colagiovanni, John B. Colerangle, Roger Collins, Rebecca Dabora, Jill A. Dalton, Kevin H. Denny, Rodney R. Dietert, Forbes P. Donald, J. Neil Duncan, John T. Farmer, Ali S. Faqi, Stephen Frantz, Les Freshwater, Tobias C. Fuchs, David V. Gauvin, Martin David Green, Lining Guo, Scott P. Henry, Philip G. Hewitt, Alan Hoberman, Ho-Wah Hui, Julia Y. Hui, Colleen Johnson, John W. Kille, Andrea S. Kim, Tae-Won Kim, Neil Kirby, Douglas Kornbrust, Douglas B. Learn, Thomas Lee, Elise Lewis, Steven Matsumoto, David L. McCormick, Kathleen B. Meyer-Tamaki, Odete R. Mendes, Michael V. Milburn, Igor Mikaelian, LaRonda L. Morford, John Nicolette, Paul Nugent, Hyesun H. Oh, Lekan Oyejide, Meg Ramos, Kelly A. Regal, David Rehagen, John Cody Resendez, John A. Ryals, Christopher P. Sambuco, Michael Schrag, David G. Serota, Raja Settivari, Richard Slauter, Christopher W. Stewart, Donald Stump, Sekhar Surapaneni, Michael Templin, Bjorn A. Thorsrud, Germaine L. Truisi, Chang Vangyi, Tom Vidmar, Jim Vrbanac, Qingli Wang, Zheng J. Wang, Lawrence O. Whitely, James S. Yan, Malcolm J. York, Husam S. Younis
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6
المؤلفون: Kent L. Kunze, Kelly A. Regal, Sidney D. Nelson, Raimund M. Peter
المصدر: Drug Metabolism and Disposition.
مصطلحات موضوعية: Pharmacology, Stereochemistry, Stable isotope ratio, Pharmaceutical Science, Deuterium, Hydrogen atom abstraction, Catalysis, chemistry.chemical_compound, chemistry, Cytochrome P-450 CYP1A2, Caffeine, Kinetic isotope effect, medicine, Humans, Theophylline, Oxidation-Reduction, Theobromine, Paraxanthine, Methyl group, Demethylation, medicine.drug
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7
المصدر: Chemical research in toxicology. 13(4)
مصطلحات موضوعية: Male, Trifluoromethyl, Chromatography, biology, Kinetics, Cytochrome P450, Substrate (chemistry), General Medicine, Glutathione, Toxicology, Mass Spectrometry, Rats, Inbred F344, Rats, Superoxide dismutase, chemistry.chemical_compound, Apoenzymes, chemistry, Catalase, Coumarins, Cytochrome P-450 CYP2B1, biology.protein, Animals, Enzyme Inhibitors, Sodium cyanide
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8
المؤلفون: Kelly A. Regal, Raimund M. Peter, William N. Howald, Kent L. Kunze, Carlos A. Gartner, Sidney D. Nelson
المصدر: Journal of chromatography. B, Biomedical sciences and applications. 708(1-2)
مصطلحات موضوعية: Chromatography, Metabolite, Primary metabolite, General Chemistry, Isotope dilution, In Vitro Techniques, High-performance liquid chromatography, Sensitivity and Specificity, Gas Chromatography-Mass Spectrometry, chemistry.chemical_compound, chemistry, 1,3,7-Trimethyluric acid, Caffeine, medicine, Microsomes, Liver, Humans, Gas chromatography–mass spectrometry, Theobromine, Chromatography, High Pressure Liquid, Paraxanthine, medicine.drug
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9Academic Journal
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.532.579; http://dmd.aspetjournals.org/content/early/2005/08/31/dmd.105.006031.full.pdf