المؤلفون: Zuzana Cihlarova, Jan Kubovciak, Margarita Sobol, Katerina Krejcikova, Jana Sachova, Michal Kolar, David Stanek, Cyril Barinka, Grace Yoon, Keith W. Caldecott, Hana Hanzlikova

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/b2171acc68da4971bf5ba54158e90c31

المؤلفون: Hana Hanzlikova, Evgeniia Prokhorova, Katerina Krejcikova, Zuzana Cihlarova, Ilona Kalasova, Jan Kubovciak, Jana Sachova, Richard Hailstone, Jan Brazina, Shereen Ghosh, Sebahattin Cirak, Joseph G. Gleeson, Ivan Ahel, Keith W. Caldecott

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/412587429a3944ccb397a069e9334d8c

المؤلفون: Fernando Gómez-Herreros, Guido Zagnoli-Vieira, Ioanna Ntai, María Isabel Martínez-Macías, Rhona M. Anderson, Andrés Herrero-Ruíz, Keith W. Caldecott

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d099d05d2c184826b76c100d842728a2

المؤلفون: Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f4adc148d44f418d9df058242e7f3bd6

المؤلفون: Gabrielle J. Grundy, Stuart L. Rulten, Raquel Arribas-Bosacoma, Kathryn Davidson, Zuzanna Kozik, Antony W. Oliver, Laurence H. Pearl, Keith W. Caldecott

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f76baaf3e5cb4dc5b122d503eff9616e

المؤلفون: Autumn C. Holmes, Guido Zagnoli-Vieira, Keith W. Caldecott, Bert L. Semler

المصدر: Viruses, Vol 12, Iss 2, p 166 (2020)

مصطلحات موضوعية: vpg unlinkase, tdp2 (tyrosyl dna phosphodiesterase 2), picornavirus, poliovirus, coxsackievirus, rna replication, viral translation, retinal pigment epithelial cells (rpe cells), polysome analysis, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4915/12/2/166; https://doaj.org/toc/1999-4915

URL الوصول: https://doaj.org/article/7a4eea0050444510a534ffea92224018

المؤلفون: Sonia Maciejewski, Joseph H. C. Nguyen, Fernando Gómez-Herreros, Felipe Cortés-Ledesma, Keith W. Caldecott, Bert L. Semler

المصدر: mBio, Vol 7, Iss 1 (2016)

مصطلحات موضوعية: Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/ba5bf0734fdd463c929c7efb532d9693

المؤلفون: Alice Meroni, Sophie E. Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W. Caldecott, Alessandro Vindigni

المصدر: bioRxiv

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0f838238ce33f4239c3fbdd36c7df2
https://doi.org/10.1101/2023.05.02.539129

المؤلفون: Mark J. O'Connor, Alan Lau, Keith W. Caldecott, Niall M.B. Martin, David Rudge, Jos Jonkers, Sven Rottenberg, Marina Pajic, Robert H. Bradbury, Attilla Ting, Bastiaan Evers, Charlotte Knights, Louise Jones, Janneke E. Jaspers, Henry Brown, Rajesh Odedra, Aaron N. Cranston, Stuart L. Rulten, Lenka Oplustil O'Connor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2109b65c80b64c5dc8e0c07cc7793822
https://doi.org/10.1158/0008-5472.c.6508109

المؤلفون: Mark J. O'Connor, Alan Lau, Keith W. Caldecott, Niall M.B. Martin, David Rudge, Jos Jonkers, Sven Rottenberg, Marina Pajic, Robert H. Bradbury, Attilla Ting, Bastiaan Evers, Charlotte Knights, Louise Jones, Janneke E. Jaspers, Henry Brown, Rajesh Odedra, Aaron N. Cranston, Stuart L. Rulten, Lenka Oplustil O'Connor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730097b7c140c8178ff65dd44a170b76
https://doi.org/10.1158/0008-5472.22410926.v1

المؤلفون: Keith W. Caldecott, Michael E. Ward, André Nussenzweig

المصدر: Nature Genetics. 54:115-120

مصطلحات موضوعية: Genetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7bfea4307d08215ae7176f10b2c6e0b
https://doi.org/10.1038/s41588-021-01001-y

المؤلفون: Keith W. Caldecott, Zhengping Shao, Kouji Hirota, Annie A. Demin, Shan Zha, Jan Brazina, Hana Hanzlikova, Shunichi Takeda, Marek Adamowicz, Masataka Tsuda, William Gittens, Richard Hailstone, Ilona Kalasova, Hiroyuki Sasanuma

المصدر: Molecular Cell

مصطلحات موضوعية: Scaffold protein, XRCC1 protein complexes, DNA Repair, DNA polymerase, Poly ADP ribose polymerase, PARP trapping, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, base excision repair, PARP1, Article, Cell Line, DNA Ligase ATP, 03 medical and health sciences, XRCC1, 0302 clinical medicine, Animals, Humans, single-strand breaks, DNA Breaks, Single-Stranded, Molecular Biology, PARP inhibitors, DNA Polymerase beta, Polymerase, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, biology, DNA, Cell Biology, Base excision repair, Fibroblasts, 3. Good health, Cell biology, DNA-Binding Proteins, X-ray Repair Cross Complementing Protein 1, chemistry, biology.protein, Poly(ADP-ribose) Polymerases, 030217 neurology & neurosurgery, DNA Damage, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e86818528d3dada10d5a783f3caced
http://hdl.handle.net/2433/263313

المؤلفون: William J. Nathan, Jennifer M. Colón-Mercado, Dali Zong, Kenta Shinoda, Michael E. Ward, Dongpeng Wang, Wei Wu, Maia Parsadanian, Raphael Souza Pavani, Peter J. McHugh, Seol Kyoung Jung, Steve Coon, Raffaella De Pace, Han-Yu Shih, Jacob Paiano, André Nussenzweig, Sarah E. Hill, Chongyi Chen, Solji Park, Rafael Casellas, Niek van Wietmarschen, Elsa Callen, Andres Canela, Keith W. Caldecott, Hana Hanzlikova

المصدر: Nature

مصطلحات موضوعية: Multidisciplinary, DNA Repair, DNA repair, DNA damage, Brain, DNA, Regulatory Sequences, Nucleic Acid, Biology, Article, Cell biology, chemistry.chemical_compound, PARP1, DNA demethylation, CpG site, chemistry, Enhancer, DNA Single Strand Break, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa542e6d7406cb597c12b65a7f00f105
https://doi.org/10.1038/s41586-021-03468-5

المؤلفون: Guido Zagnoli-Vieira, Keith W. Caldecott, Livia Garavelli, Edoardo Errichiello, R. Rizzi, Orsetta Zuffardi

المصدر: Journal of Human Genetics. 65:1135-1141

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Genes, Recessive, Pedigree chart, 030105 genetics & heredity, Biology, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, Exon, Loss of Function Mutation, Intellectual Disability, Genetics, medicine, Humans, Spinocerebellar Ataxias, Genetics (clinical), Loss function, Phosphoric Diester Hydrolases, Phosphodiesterase, Middle Aged, medicine.disease, DNA-Binding Proteins, 030104 developmental biology, chemistry, Speech delay, Spinocerebellar ataxia, Female, medicine.symptom, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc30d6895b4c2a7c17654153eea9af9
https://doi.org/10.1038/s10038-020-0800-4

المؤلفون: Hana Hanzlikova, Amit Gautam, Richard Hailstone, Jan Brazina, Emilia Komulainen, Marek Adamowicz, Annie A. Demin, Keith W. Caldecott, Sophie E Wells

المصدر: Nature Cell Biology

مصطلحات موضوعية: Ubiquitylation, DNA Repair, Transcription, Genetic, Poly (ADP-Ribose) Polymerase-1, Article, Histones, Mice, XRCC1, chemistry.chemical_compound, PARP1, Ubiquitin, Transcription (biology), Cell Line, Tumor, Histone post-translational modifications, Transcriptional regulation, Animals, Humans, DNA Breaks, Single-Stranded, Mice, Knockout, biology, Ubiquitination, DNA, Hydrogen Peroxide, Cell Biology, Base excision repair, Single-strand DNA breaks, Cell biology, Oxidative Stress, X-ray Repair Cross Complementing Protein 1, Histone, chemistry, biology.protein, Ubiquitin-Specific Proteases, Transcription

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec94f2484cfa1a3b1a909eec53b54d27
http://sro.sussex.ac.uk/id/eprint/103092/1/s41556-021-00792-w.pdf

المؤلفون: Zuzana Cihlarova, Jan Kubovciak, Margarita Sobol, Katerina Krejcikova, Jana Sachova, Michal Kolar, David Stanek, Cyril Barinka, Grace Yoon, Keith W. Caldecott, Hana Hanzlikova

المصدر: Nature communications. 13(1)

مصطلحات موضوعية: Histones, Multidisciplinary, Phenotype, Mutation, General Physics and Astronomy, Humans, Nuclear Proteins, Neurodegenerative Diseases, General Chemistry, RNA Processing, Post-Transcriptional, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e7f98581d42502a0a83f28775a617a
https://pubmed.ncbi.nlm.nih.gov/36028512

المؤلفون: Xiuji Cui, Rebecca McAllister, Rajeev Boregowda, Ji A Sohn, Felipe Cortes Ledesma, Keith W Caldecott, Christoph Seeger, Jianming Hu

المصدر: PLoS ONE, Vol 10, Iss 6, p e0128401 (2015)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC4469307?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/fab186e946174a278756f4c7113ea22b

الاتاحة: https://doi.org/10.1371/journal.pone.0128401
https://doaj.org/article/fab186e946174a278756f4c7113ea22b

المؤلفون: Keith W, Caldecott, Michael E, Ward, André, Nussenzweig

المصدر: Nature genetics. 54(2)

مصطلحات موضوعية: Neurons, Epigenome, Genome, DNA Repair, Genome, Human, DNA Breaks, Mutation, Animals, Brain, Humans, Nervous System Diseases, Regulatory Sequences, Nucleic Acid, DNA Topoisomerases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c480b6ad1806cba14f7600c2e5ce12a7
https://pubmed.ncbi.nlm.nih.gov/35145299

المؤلفون: Hana Hanzlikova, Keith W. Caldecott, Vaitsiankova A, Burdova K

مصطلحات موضوعية: chemistry.chemical_compound, Nuclease, PARP1, Okazaki fragments, chemistry, biology, Poly ADP ribose polymerase, PARP inhibitor, Wild type, DNA replication, biology.protein, DNA, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::600695a082c17558509e8fc5484257d2
https://doi.org/10.1101/2021.07.03.450982

المؤلفون: Alina Vaitsiankova, Kamila Burdova, Margarita Sobol, Amit Gautam, Oldrich Benada, Hana Hanzlikova, Keith W. Caldecott

المصدر: Nature structuralmolecular biology. 29(4)

مصطلحات موضوعية: DNA Replication, DNA Repair, Structural Biology, Poly (ADP-Ribose) Polymerase-1, DNA, Poly(ADP-ribose) Polymerase Inhibitors, Molecular Biology, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7c3f239ccfd875219da8f36a8e64a0
https://pubmed.ncbi.nlm.nih.gov/35332322