-
1Academic JournalDiscovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX‑1 in Ovarian Cancer
المؤلفون: Md. Jashim Uddin, Andrew J. Wilson, Brenda C. Crews, Paola Malerba, Md. Imam Uddin, Philip J. Kingsley, Kebreab Ghebreselasie, Cristina K. Daniel, Michael L. Nickels, Mohammed N. Tantawy, Elma Jashim, H. Charles Manning, Dineo Khabele, Lawrence J. Marnett
المصدر: ACS Omega, Vol 4, Iss 5, Pp 9251-9261 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
-
2
المؤلفون: Lawrence J. Marnett, Jeffery Reese, Mohammed N. Tantawy, Mohammad Sib Ansari, Philip J. Kingsley, Imran Huda, Kebreab Ghebreselasie, Brenda C. Crews, Md. Jashim Uddin
-
3
المؤلفون: Lawrence J. Marnett, Jeffery Reese, Mohammed N. Tantawy, Mohammad Sib Ansari, Philip J. Kingsley, Imran Huda, Kebreab Ghebreselasie, Brenda C. Crews, Md. Jashim Uddin
-
4
المؤلفون: Lawrence J. Marnett, Jeffery Reese, Mohammed N. Tantawy, Mohammad Sib Ansari, Philip J. Kingsley, Imran Huda, Kebreab Ghebreselasie, Brenda C. Crews, Md. Jashim Uddin
-
5
المؤلفون: Brenda C. Crews, Ansari M. Aleem, Jashim Uddin, Redoan A Salam, Lawrence J. Marnett, Cristina K. Daniel, Paola Malerba, Kebreab Ghebreselasie, Elma Jashim
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: chemistry.chemical_classification, endocrine system diseases, biology, Organic Chemistry, medicine.disease, Biochemistry, Optical imaging, Enzyme, chemistry, In vivo, Drug Discovery, Cancer research, medicine, biology.protein, Light emission, Cyclooxygenase, Ovarian cancer, IC50, Intracellular
-
6
المؤلفون: Surajit Banerjee, Michael C. Goodman, Shu Xu, Marco Migliore, Lawrence J. Marnett, Daniele Piomelli, Carol A. Rouzer, Kebreab Ghebreselasie
المصدر: Journal of Biological Chemistry. 293:3028-3038
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Flurbiprofen, Phenylcarbamates, Biochemistry, Amidohydrolases, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Fatty acid amide hydrolase, Catalytic Domain, medicine, Cyclooxygenase Inhibitors, Molecular Biology, chemistry.chemical_classification, Phenylpropionates, Fatty acid metabolism, Fatty acid, Stereoisomerism, Cell Biology, Oxidoreductase inhibitor, Enzyme structure, Isoenzymes, 030104 developmental biology, chemistry, Prostaglandin-Endoperoxide Synthases, Enzymology, lipids (amino acids, peptides, and proteins), Arachidonic acid, Prostaglandin H2, Protein Binding, medicine.drug
-
7
المؤلفون: Lawrence J. Marnett, Surajit Banerjee, Kebreab Ghebreselasie, Ansari M. Aleem, Md. Jashim Uddin, Shu Xu, Brenda C. Crews
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: chemistry.chemical_classification, Indole test, biology, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Substituent, Oxidoreductase inhibitor, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Harmaline, chemistry, Drug Discovery, biology.protein, Arachidonic acid, Cyclooxygenase, IC50, Tricyclic
-
8
المؤلفون: Surajit Banerjee, Kebreab Ghebreselasie, Shu Xu, Carol A. Rouzer, Joel Musee, Md. Jashim Uddin, Kelsey C. Duggan, James R. Kiefer, Lawrence J. Marnett
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Time Factors, Stereochemistry, Indomethacin, Biochemistry, Fluorescence, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Amide, Catalytic Domain, Moiety, Animals, Editors' Picks, Enzyme kinetics, Molecular Biology, chemistry.chemical_classification, Dansyl Compounds, 030102 biochemistry & molecular biology, biology, Cyclooxygenase 2 Inhibitors, Cell Membrane, Active site, Cell Biology, Oxidoreductase inhibitor, Enzyme structure, Kinetics, 030104 developmental biology, Enzyme, chemistry, Cyclooxygenase 2, biology.protein, Linker
-
9Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer
المؤلفون: Cristina K. Daniel, Dineo Khabele, Brenda C. Crews, Mohammed N. Tantawy, Michael L. Nickels, Philip J. Kingsley, H. Charles Manning, Paola Malerba, Imam Uddin, Kebreab Ghebreselasie, Lawrence J. Marnett, Andrew J. Wilson, Elma Jashim, Jashim Uddin
المصدر: ACS Omega, Vol 4, Iss 5, Pp 9251-9261 (2019)
مصطلحات موضوعية: 0303 health sciences, Treatment response, medicine.diagnostic_test, business.industry, General Chemical Engineering, Radiosynthesis, Early detection, General Chemistry, Therapeutic evaluation, medicine.disease, Imaging agent, 3. Good health, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, lcsh:QD1-999, In vivo, Positron emission tomography, 030220 oncology & carcinogenesis, Cancer research, Medicine, business, Ovarian cancer, 030304 developmental biology
-
10
المؤلفون: Kebreab Ghebreselasie, Lawrence J. Marnett, Shu Xu, Md. Jashim Uddin, Philip J. Kingsley, Surajit Banerjee, Brenda C. Crews, Cristina K. Daniel
المصدر: ACS Chemical Biology. 11:3052-3060
مصطلحات موضوعية: 0301 basic medicine, media_common.quotation_subject, Mice, Nude, Antineoplastic Agents, Pharmacology, Crystallography, X-Ray, Biochemistry, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, Internalization, Cytotoxicity, media_common, Cyclooxygenase 2 Inhibitors, biology, Chemistry, General Medicine, In vitro, Kinetics, 030104 developmental biology, Podophyllotoxin, Cell culture, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Molecular Medicine, Cyclooxygenase, Conjugate, medicine.drug
-
11
المؤلفون: Terry P. Lybrand, Jeffery J. Prusakiewicz, Christopher W. Moth, Anna L. Blobaum, Dapo Akingbade, Shu Xu, Carol A. Rouzer, Aaron T. Jacobs, Kebreab Ghebreselasie, Lawrence J. Marnett, Mary E. Konkle
المصدر: Biochemistry
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Carboxylic acid, Indomethacin, Biochemistry, Article, Protein Structure, Secondary, Structure-Activity Relationship, 03 medical and health sciences, Enzyme activator, chemistry.chemical_compound, Amide, Structure–activity relationship, Moiety, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Chemistry, Computational Biology, Active site, Esters, Amides, 3. Good health, Enzyme Activation, Enzyme, Cyclooxygenase 2, biology.protein, Cyclooxygenase
-
12
المؤلفون: Shu Xu, Scott W. Rowlinson, Kebreab Ghebreselasie, Lawrence J. Marnett, Shalley N. Kudalkar, William R. Birmingham, Kelsey C. Duggan, Surajit Banerjee, Anna L. Blobaum
المصدر: Journal of Biological Chemistry. 290:12793-12803
مصطلحات موضوعية: chemistry.chemical_classification, biology, Flurbiprofen, Mutagenesis, Tryptophan, Active site, Cell Biology, Biochemistry, chemistry.chemical_compound, Enzyme, chemistry, Enzyme inhibitor, biology.protein, medicine, Cyclooxygenase, Molecular Biology, Prostaglandin G2, medicine.drug
-
13
المؤلفون: Kellie D. Nance, Lawrence J. Marnett, Kebreab Ghebreselasie, Brenda C. Crews, Md. Jashim Uddin, Anna V. Elleman, Cristina K. Daniel, Tamanna Huda
المصدر: ACS Medicinal Chemistry Letters. 5:1254-1258
مصطلحات موضوعية: Scaffold, business.industry, Organic Chemistry, Cell, Fluorine containing, medicine.disease, Ring (chemistry), Bioinformatics, Biochemistry, Combinatorial chemistry, Imaging agent, medicine.anatomical_structure, Drug Discovery, medicine, Structure–activity relationship, Ovarian cancer, business, Human cancer
-
14
المؤلفون: R. Michael Garavito, Gina M. Clayton, Kebreab Ghebreselasie, Lawrence J. Marnett, Daniel J. Hermanson, Surajit Banerjee, Shu Xu
المصدر: Journal of Biological Chemistry. 289:6799-6808
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Thiazines, Carboxamide, Arginine, Meloxicam, Biochemistry, Protein Structure, Secondary, Mice, Piroxicam, chemistry.chemical_compound, Leucine, Thiazine, Catalytic Domain, Serine, medicine, Animals, Cyclooxygenase Inhibitors, Molecular Biology, Binding Sites, biology, Hydrogen bond, Anti-Inflammatory Agents, Non-Steroidal, Water, Active site, Hydrogen Bonding, Cell Biology, Lipids, Enzyme structure, Isoxicam, Thiazoles, Amino Acid Substitution, chemistry, Cyclooxygenase 2, Oxicam, Mutation, Cyclooxygenase 1, biology.protein, Tyrosine, medicine.drug
-
15
المؤلفون: Md. Jashim Uddin, Lawrence J. Marnett, Cristina K. Daniel, Brenda C. Crews, Kebreab Ghebreselasie, Imran Huda
المصدر: ACS Medicinal Chemistry Letters. 5:446-450
مصطلحات موضوعية: Pathology, medicine.medical_specialty, biology, business.industry, medicine.medical_treatment, Organic Chemistry, Intraperitoneal injection, Cancer, Inflammation, medicine.disease, Biochemistry, In vitro, In vivo, Cell culture, Drug Discovery, medicine, Cancer research, biology.protein, Potency, Cyclooxygenase, medicine.symptom, business
-
16
المؤلفون: Brenda C. Crews, Andy J. Liedtke, Kebreab Ghebreselasie, Lawrence J. Marnett, Cristina Daniel, Anna L. Blobaum, Philip J. Kingsley
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Antineoplastic Agents, Pharmacology, 01 natural sciences, Article, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Sulindac, Biosynthesis, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Cyclooxygenase Inhibitors, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Sheep, Cyclooxygenase 2 Inhibitors, biology, 010405 organic chemistry, Cell growth, Chemistry, Stereoisomerism, Metabolism, Lipid signaling, 0104 chemical sciences, 3. Good health, Biochemistry, Cyclooxygenase 1, biology.protein, Molecular Medicine, Female, Arachidonic acid, Cyclooxygenase, Drug Screening Assays, Antitumor, Hydrophobic and Hydrophilic Interactions, medicine.drug
-
17
المؤلفون: Philip J. Kingsley, Jeffery Reese, Brenda C. Crews, Mohammed N. Tantawy, Imran Huda, Md. Jashim Uddin, Mohammad Sib Ansari, Kebreab Ghebreselasie, Lawrence J. Marnett
المصدر: Cancer Prevention Research. 4:1536-1545
مصطلحات موضوعية: Male, Cancer Research, Halogenation, Indomethacin, Mice, Nude, Inflammation, Pharmacology, Inhibitory postsynaptic potential, Article, Rats, Sprague-Dawley, Mice, In vivo, Neoplasms, Tumor Cells, Cultured, medicine, Animals, Humans, Sulfonamides, Cyclooxygenase 2 Inhibitors, medicine.diagnostic_test, Chemistry, Cancer, medicine.disease, In vitro, Molecular Imaging, Rats, Oncology, Celecoxib, Positron emission tomography, Positron-Emission Tomography, Pyrazoles, Female, Radiopharmaceuticals, Molecular imaging, medicine.symptom, medicine.drug
-
18
المؤلفون: Philip J. Kingsley, Anna L. Blobaum, Ronald M. Baldwin, Lawrence J. Marnett, Md. Jashim Uddin, J.A. Clanton, Sam S. Saleh, Kebreab Ghebreselasie, Brenda C. Crews
المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 52:387-393
مصطلحات موضوعية: chemistry.chemical_classification, biology, medicine.drug_class, Organic Chemistry, chemistry.chemical_element, Carboxamide, Biochemistry, Chemical synthesis, Analytical Chemistry, chemistry.chemical_compound, Enzyme, chemistry, Enzyme inhibitor, Yield (chemistry), Drug Discovery, medicine, biology.protein, Organic chemistry, Radiology, Nuclear Medicine and imaging, Triphenylphosphine, Spectroscopy, Acetamide, Nuclear chemistry, Palladium
-
19
المؤلفون: Shu Xu, Matthias Scholz, Lawrence J. Marnett, Menyhárt B. Sárosi, Brenda C. Crews, Wilma Neumann, h.c. Evamarie Hey-Hawkins, Surajit Banerjee, Kebreab Ghebreselasie
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Indomethacin, Selective inhibition, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Mice, Structure-Activity Relationship, Drug Discovery, Animals, General Pharmacology, Toxicology and Pharmaceutics, Solubility, Boranes, Pharmacology, chemistry.chemical_classification, Binding Sites, Sheep, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, 0104 chemical sciences, Inhibitory potency, Enzyme, chemistry, Cyclooxygenase 2, biology.protein, Molecular Medicine, Cyclooxygenase, Pharmacophore, Selectivity
-
20
المؤلفون: Kebreab Ghebreselasie, Lawrence J. Marnett, Carol A. Rouzer
المصدر: Chemistry and Physics of Lipids. 119:69-82
مصطلحات موضوعية: Tris, Receptors, Drug, Arachidonic Acids, Buffers, Ligands, Biochemistry, High-performance liquid chromatography, Glycerides, chemistry.chemical_compound, Drug Stability, Molecule, Receptors, Cannabinoid, Molecular Biology, Incubation, Chromatography, High Pressure Liquid, Detection limit, Chromatography, Ligand, Organic Chemistry, Cell Biology, Culture Media, chemistry, Ionic strength, Chemical stability, Oxidation-Reduction, Endocannabinoids
Full Text Finder