المؤلفون: Nie, Zhe, Bonnert, Roger, Tsien, Jet, Deng, Xiaoyi, Higgs, Christopher, El Mazouni, Farah, Zhang, Xiaoyu, Li, Renzhe, Ho, Nhi, Feher, Victoria, Paulsen, Janet, Shackleford, David M., Katneni, Kasiram, Chen, Gong, Ng, Alice C. F., McInerney, Mitchell, Wang, Wen, Saunders, Jessica, Collins, Daniel, Yan, Dandan, Li, Peng, Campbell, Michael, Patil, Rahul, Ghoshal, Atanu, Mondal, Pallab, Kundu, Abhijit, Chittimalla, Rajesh, Mahadeva, Muralikumar, Kokkonda, Sreekanth, White, John, Das, Rishi, Mukherjee, Partha, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Malmstrom, Robert, Lawrenz, Morgan, Rodriguez-Granillo, Agustina, Rathod, Pradipsinh K., Tomchick, Diana R., Palmer, Michael J., Laleu, Benoît, Qin, Tian, Charman, Susan A., Phillips, Margaret A.

المساهمون: Welch Foundation, Bill and Melinda Gates Foundation, Medicines for Malaria Venture, U.S. Department of Energy, National Institutes of Health

المصدر: Journal of Medicinal Chemistry ; volume 68, issue 1, page 590-637 ; ISSN 0022-2623 1520-4804

الاتاحة: https://doi.org/10.1021/acs.jmedchem.4c02394
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c02394

المؤلفون: Nie, Zhe, Bonnert, Roger, Tsien, Jet, Deng, Xiaoyi, Higgs, Christopher, El Mazouni, Farah, Zhang, Xiaoyu, Li, Renzhe, Ho, Nhi, Feher, Victoria, Paulsen, Janet, Shackleford, David M., Katneni, Kasiram, Chen, Gong, Ng, Alice C. F., McInerney, Mitchell, Wang, Wen, Saunders, Jessica, Collins, Daniel, Yan, Dandan

المصدر: Journal of Medicinal Chemistry; 1/9/2025, Vol. 68 Issue 1, p590-637, 48p

المؤلفون: Braillard, Stéphanie, Keenan, Martine, Breese, Karen J., Heppell, Jacob, Abbott, Michael, Islam, Rafiqul, Shackleford, David M., Katneni, Kasiram, Crighton, Elly, Chen, Gong, Patil, Rahul, Lee, Given, White, Karen L., Carvalho, Sandra, Wall, Richard J., Chemi, Giulia, Zuccotto, Fabio, Gonzalez, Silvia, Marco, Maria, Deakyne, Julianna, Standing, David, Brunori, Gino, Lyon, Jonathan J., Castañeda-Casado, Pablo, Camino, Isabel, Martinez Martinez, Maria S., Zulfiqar, Bilal, Avery, Vicky M., Feijens, Pim-Bart, Van Pelt, Natascha, Matheeussen, An, Hendrickx, Sarah, Maes, Louis, Caljon, Guy, Yardley, Vanessa, Wyllie, Susan, Charman, Susan A., Chatelain, Eric

المصدر: Braillard , S , Keenan , M , Breese , K J , Heppell , J , Abbott , M , Islam , R , Shackleford , D M , Katneni , K , Crighton , E , Chen , G , Patil , R , Lee , G , White , K L , Carvalho , S , Wall , R J , Chemi , G , Zuccotto , F , Gonzalez , S , Marco , M , Deakyne , J , Standing , D , Brunori , G , Lyon , J J , Castañeda-Casado , ....

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/834df077-1345-4a01-bd6b-8f58a6c672e7
https://doi.org/10.1126/scitranslmed.adh9902
https://discovery.dundee.ac.uk/ws/files/116343034/adh9902_Article_Content_Suppl_Info_Combined_FINAL_17112023_CLEAN.pdf

المؤلفون: Leas, Derek A., Keiser, Jennifer, Charman, Susan A., Shackleford, David M., Jones, Jeremy O., Campbell, Michael, Chen, Gong, Katneni, Kasiram, Patil, Rahul, Hu, Meiyu, Pham, Thao, Häberli, Cécile, Schulze, Thomas T., Neville, Andrew J., Wang, Xiaofang, Dong, Yuxiang, Davis, Paul H., Vennerstrom, Jonathan L.

المصدر: ACS Infectious Diseases; 11/8/2024, Vol. 10 Issue 11, p3963-3972, 10p

المؤلفون: Ren, Rongguo, Leas, Derek A., Häberli, Cécile, Cal, Monica, Chen, Gong, Katneni, Kasiram, Dong, Yuxiang, Kaiser, Marcel, Keiser, Jennifer, Charman, Susan A., Vennerstrom, Jonathan L.

المصدر: Journal of Medicinal Chemistry; 10/24/2024, Vol. 67 Issue 20, p18235-18246, 12p

المؤلفون: Calleja, Dale J., Kuchel, Nathan, Lu, Bernadine G. C., Birkinshaw, Richard W., Klemm, Theresa, Doerflinger, Marcel, Cooney, James P., Mackiewicz, Liana, Au, Amanda E., Yap, Yu Q., Blackmore, Timothy R, Katneni, Kasiram, Crighton, Elly, Newman, Janet, Jarman, Kate E., Call, Melissa J., Lechtenberg, Bernhard C., Czabotar, Peter E., Pellegrini, Marc, Charman, Susan A., Lowes, Kym N., Mitchell, Jeffrey P., Nachbur, Ueli, Lessene, Guillaume, Komander, David

المساهمون: National Health and Medical Research Council, Wellcome Trust

المصدر: Frontiers in Chemistry ; volume 10 ; ISSN 2296-2646

الاتاحة: http://dx.doi.org/10.3389/fchem.2022.861209
https://www.frontiersin.org/articles/10.3389/fchem.2022.861209/full

المؤلفون: Lauterwasser, Erica MW, Fontaine, Shaun D, Li, Hao, Gut, Jiri, Katneni, Kasiram, Charman, Susan A, Rosenthal, Philip J, Bogyo, Matthew, Renslo, Adam R

المصدر: ACS Medicinal Chemistry Letters. 6(11)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Organic Chemistry, Chemical Sciences, Neurosciences, Brain Disorders, Vector-Borne Diseases, Malaria, Rare Diseases, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, antimalarial, trioxolane, mefloquine, drug delivery, Pharmacology and Pharmaceutical Sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5554w0db

المؤلفون: Laleu, Benoît, Akao, Yuichiro, Ochida, Atsuko, Duffy, Sandra, Lucantoni, Leonardo, Shackleford, David M, Chen, Gong, Katneni, Kasiram, Chiu, Francis CK, White, Karen L, Chen, Xue, Sturm, Angelika, Dechering, Koen J, Avery, Vicky M

مصطلحات موضوعية: Macromolecular and materials chemistry, Organic chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry

Relation: Journal of Medicinal Chemistry; Laleu, B; Akao, Y; Ochida, A; Duffy, S; Lucantoni, L; Shackleford, DM; Chen, G; Katneni, K; Chiu, FCK; White, KL; Chen, X; Sturm, A; Dechering, KJ; Avery, VMet al., Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials, Journal of Medicinal Chemistry, 2021; http://hdl.handle.net/10072/407383

الاتاحة: http://hdl.handle.net/10072/407383
https://doi.org/10.1021/acs.jmedchem.1c00441

المؤلفون: Shackleford, David M., Chiu, Francis C. K., Katneni, Kasiram, Blundell, Scott, McLaren, Jenna, Wang, Xiaofang, Zhou, Lin, Sriraghavan, Kamaraj, Alker, André M., Hunziker, Daniel, Scheurer, Christian, Zhao, Qingjie, Dong, Yuxiang, Möhrle, Jörg J., Abla, Nada, Matile, Hugues, Wittlin, Sergio, Vennerstrom, Jonathan L., Charman, Susan A.

المساهمون: Medicines for Malaria Venture, Nebraska Research Initiative

المصدر: ACS Infectious Diseases ; volume 7, issue 7, page 1885-1893 ; ISSN 2373-8227 2373-8227

الاتاحة: http://dx.doi.org/10.1021/acsinfecdis.1c00225
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00225

المؤلفون: Trevaskis, Natalie L., Lee, Given, Escott, Alistair, Phang, Kian Liun, Hong, Jiwon, Cao, Enyuan, Katneni, Kasiram, Charman, Susan A., Han, Sifei, Charman, William N., Phillips, Anthony R.J., Windsor, John A., Porter, Christopher J.H.

المصدر: Trevaskis , N L , Lee , G , Escott , A , Phang , K L , Hong , J , Cao , E , Katneni , K , Charman , S A , Han , S , Charman , W N , Phillips , A R J , Windsor , J A & Porter , C J H 2020 , ' Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans ' , Frontiers in Physiology , vol. 11 , 458 . https://doi.org/10.3389/fphys.2020.00458

مصطلحات موضوعية: allometric, drug, flow, human, intestine, lipid, lymph, lymphatic

وصف الملف: application/pdf

الاتاحة: https://research.monash.edu/en/publications/fbc57129-67c2-448d-b901-441f60cca8f2
https://doi.org/10.3389/fphys.2020.00458
https://researchmgt.monash.edu/ws/files/314558978/310619255_oa.pdf
http://www.scopus.com/inward/record.url?scp=85085877911&partnerID=8YFLogxK

المؤلفون: Charman, Susan A., Andreu, Alice, Barker, Helena, Blundell, Scott, Campbell, Anna, Campbell, Michael, Chen, Gong, Chiu, Francis C.K., Crighton, Elly, Katneni, Kasiram, Morizzi, Julia, Patil, Rahul, Pham, Thao, Ryan, Eileen, Saunders, Jessica, Shackleford, David M., White, Karen L., Almond, Lisa, Dickins, Maurice, Smith, Dennis A., Moehrle, Joerg J., Burrows, Jeremy N., Abla, Nada

المصدر: Charman , S A , Andreu , A , Barker , H , Blundell , S , Campbell , A , Campbell , M , Chen , G , Chiu , F C K , Crighton , E , Katneni , K , Morizzi , J , Patil , R , Pham , T , Ryan , E , Saunders , J , Shackleford , D M , White , K L , Almond , L , Dickins , M , Smith , D A , Moehrle , J J , Burrows , J N & Abla , N ....

مصطلحات موضوعية: Anti-malarial drugs, Biorelevant solubility, Blood to plasma partitioning, CYP inhibition, Ionization constant, Microsomal stability, Partition coefficient, Physiologically-based pharmacokinetic modelling, Protein binding

وصف الملف: application/pdf

الاتاحة: https://research.monash.edu/en/publications/2c3c60db-f68b-48e5-a7b1-1910e49c3065
https://doi.org/10.1186/s12936-019-3075-5
https://researchmgt.monash.edu/ws/files/299940182/295024887_oa.pdf
http://www.scopus.com/inward/record.url?scp=85077398282&partnerID=8YFLogxK

المؤلفون: Braillard, Stéphanie, Keenan, Martine, Breese, Karen J., Heppell, Jacob, Abbott, Michael, Islam, Rafiqul, Shackleford, David M., Katneni, Kasiram, Crighton, Elly, Chen, Gong, Patil, Rahul, Lee, Given, White, Karen L., Carvalho, Sandra, Wall, Richard J., Chemi, Giulia, Zuccotto, Fabio, González, Silvia, Marco, Maria, Deakyne, Julianna

المصدر: Science Translational Medicine; 12/13/2023, Vol. 15 Issue 726, p1-15, 15p

مصطلحات موضوعية: VISCERAL leishmaniasis, CHAGAS' disease, NEGLECTED diseases, PARASITIC diseases, PARASITES

المؤلفون: Katneni, Kasiram, Pham, Thao, Saunders, Jessica, Chen, Gong, Patil, Rahul, White, Karen L., Abla, Nada, Chiu, Francis C.K., Shackleford, David M., Charman, Susan A.

المصدر: Katneni , K , Pham , T , Saunders , J , Chen , G , Patil , R , White , K L , Abla , N , Chiu , F C K , Shackleford , D M & Charman , S A 2018 , ' Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds ' , Pharmaceutical Research , vol. 35 , no. 11 , 210 . https://doi.org/10.1007/s11095-018-2493-3

مصطلحات موضوعية: Caco-2 permeability, human plasma protein binding, lipophilic compounds

وصف الملف: application/pdf

الاتاحة: https://research.monash.edu/en/publications/86fd3edf-e33e-4071-b28b-f45c90c6be04
https://doi.org/10.1007/s11095-018-2493-3
https://researchmgt.monash.edu/ws/files/274271129/256603207_oa.pdf
http://www.scopus.com/inward/record.url?scp=85053424328&partnerID=8YFLogxK

المؤلفون: Ren, Rongguo, Wang, Xiaofang, Leas, Derek A., Scheurer, Christian, Hoevel, Sarah, Cal, Monica, Chen, Gong, Zhong, Longjin, Katneni, Kasiram, Pham, Thao, Patil, Rahul, Sil, Diptesh, Walters, Matthias J., Schulze, Thomas T., Neville, Andrew J., Dong, Yuxiang, Wittlin, Sergio, Kaiser, Marcel, Davis, Paul H., Charman, Susan A.

المصدر: ACS Infectious Diseases; 10/13/2024, Vol. 9 Issue 10, p1964-1980, 17p

المؤلفون: Doggett, J. Stone, Nilsen, Aaron, Forquer, Isaac, Wegmann, Keith W., Jones-Brando, Lorraine, Yolken, Robert H., Bordón, Claudia, Charman, Susan A., Katneni, Kasiram, Schultz, Tracey, Burrows, Jeremy N., Hinrichs, David J., Meunier, Brigitte, Carruthers, Vern B., Riscoe, Michael K.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2012 Sep . 109(39), 15936-15941.

URL الوصول: https://www.jstor.org/stable/41763342

المؤلفون: Abla, Nada, Bashyam, Sridevi, Charman, Susan A., Greco, Béatrice, Hewitt, Philip, Jiménez-Díaz, Maria Belén, Katneni, Kasiram, Kubas, Holger, Picard, Didier, Sambandan, Yuvaraj, Sanz, Laura, Smith, Dennis, Wang, Tai, Willis, Paul, Wittlin, Sergio, Spangenberg, Thomas

المصدر: Abla , N , Bashyam , S , Charman , S A , Greco , B , Hewitt , P , Jiménez-Díaz , M B , Katneni , K , Kubas , H , Picard , D , Sambandan , Y , Sanz , L , Smith , D , Wang , T , Willis , P , Wittlin , S & Spangenberg , T 2017 , ' Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol ' , ACS Medicinal Chemistry Letters , vol. 8 , no. 12 , pp. 1304-1308 . https://doi.org/10.1021/acsmedchemlett.7b00391

مصطلحات موضوعية: amino alcohol, Antiplasmodial, carbazole, Hsp90, pharmacodynamics, pharmacokinetics

وصف الملف: application/pdf

الاتاحة: https://research.monash.edu/en/publications/035e0c0e-dfcc-40f9-8b0c-eaa2f29a33ba
https://doi.org/10.1021/acsmedchemlett.7b00391
https://researchmgt.monash.edu/ws/files/245749637/235507222_oa.pdf
http://www.scopus.com/inward/record.url?scp=85038355663&partnerID=8YFLogxK

المؤلفون: Palmer, Michael J, Deng, Xiaoyi, Watts, Shawn, Krilov, Goran, Gerasyuto, Aleksey, Kokkonda, Sreekanth, El Mazouni, Farah, White, John, White, Karen L, Striepen, Josefine, Bath, Jade, Schindler, Kyra A, Yeo, Tomas, Shackleford, David M, Mok, Sachel, Deni, Ioanna, Lawong, Aloysus, Huang, Ann, Chen, Gong, Wang, Wen, Jayaseelan, Jaya, Katneni, Kasiram, Patil, Rahul, Saunders, Jessica, Shahi, Shatrughan P, Chittimalla, Rajesh, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Wittlin, Sergio, Tumwebaze, Patrick K, Rosenthal, Philip J, Cooper, Roland A., Campos Aguiar, Anna Caroline, Guido, Rafael V C, Pereira, Dhelio B, Mittal, Nimisha, Winzeler, Elizabeth A, Tomchick, Diana R, Laleu, Benoît, Burrows, Jeremy N, Rathod, Pradipsinh K, Fidock, David A., Charman, Susan A, Phillips, Margaret A

المصدر: Natural Sciences and Mathematics | Faculty Scholarship

مصطلحات موضوعية: Animals, Antimalarials, Dihydroorotate Dehydrogenase, Drug Design, Enzyme Inhibitors, Mice, Oxidoreductases Acting on CH-CH Group Donors, Plasmodium falciparum, Pyrroles, Structure-Activity Relationship, Medicinal and Pharmaceutical Chemistry, Parasitic Diseases

Relation: https://scholar.dominican.edu/natural-sciences-and-mathematics-faculty-scholarship/96; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171248/pdf/nihms-1702324.pdf

الاتاحة: https://scholar.dominican.edu/natural-sciences-and-mathematics-faculty-scholarship/96
https://doi.org/10.1021/acs.jmedchem.1c00173
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171248/pdf/nihms-1702324.pdf

المؤلفون: Buckley, Benjamin J., Aboelela, Ashraf, Majed, Hiwa, Bujaroski, Richard S., White, Karen L., Powell, Andrew K., Wang, Wen, Katneni, Kasiram, Saunders, Jessica, Shackleford, David M., Charman, Susan A., Cook, Gregory M., Kelso, Michael J., Ranson, Marie

المساهمون: Health Research Council of New Zealand, National Health and Medical Research Council

المصدر: Bioorganic & Medicinal Chemistry ; volume 37, page 116116 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2021.116116
https://api.elsevier.com/content/article/PII:S0968089621001243?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0968089621001243?httpAccept=text/plain

المؤلفون: Nilsen, Aaron, Miley, Galen P., Forquer, Isaac P., Mather, Michael W., Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M., Stickles, Allison M., Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L., Hinrichs, David J., Winter, Rolf W., Charman, Susan A., Zakharov, Lev N., Bathurst, Ian, Burrows, Jeremy N., Vaidya, Akhil B., Riscoe, Michael K.

المصدر: Journal of Medicinal Chemistry ; volume 57, issue 9, page 3818-3834 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm500147k
https://pubs.acs.org/doi/pdf/10.1021/jm500147k

المؤلفون: Katneni, Kasiram

مصطلحات موضوعية: ComputingMilieux_COMPUTERSANDEDUCATION, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Uncategorized

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209efc70657013040f04383100187341