المؤلفون: Benjamin Russell Lewis, Muhammad R. Uddin, Mohammad Moniruzzaman, Katie M. Kuo, Anna J. Higgins, Laila M. N. Shah, Frank Sobott, Jerry M. Parks, Dietmar Hammerschmid, James C. Gumbart, Helen I. Zgurskaya, Eamonn Reading

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/db36206389534e89aa35837123b7295a

المؤلفون: Runrun Wu, Jeremy W. Bakelar, Karl Lundquist, Zijian Zhang, Katie M. Kuo, David Ryoo, Yui Tik Pang, Chen Sun, Tommi White, Thomas Klose, Wen Jiang, James C. Gumbart, Nicholas Noinaj

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/cd323a1040434cb5be239dec28a98476

المؤلفون: Benjamin Russell Lewis, Muhammad R. Uddin, Mohammad Moniruzzaman, Katie M. Kuo, Anna J. Higgins, Laila M. N. Shah, Frank Sobott, Jerry M. Parks, Dietmar Hammerschmid, James C. Gumbart, Helen I. Zgurskaya, Eamonn Reading

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4585e9969a8c7f87dfeb44bb38352d67
https://doi.org/10.1101/2022.12.09.519754

المؤلفون: Katie M. Kuo, Samuel Itskanov, James C. Gumbart, Eunyong Park

المصدر: Nature structural & molecular biology
Nature structural & molecular biology, vol 28, iss 2

مصطلحات موضوعية: Models, Molecular, Sec61, Saccharomyces cerevisiae Proteins, 1.1 Normal biological development and functioning, Saccharomyces cerevisiae, Biophysics, Gating, Endoplasmic Reticulum, Medical and Health Sciences, Article, 03 medical and health sciences, 0302 clinical medicine, SEC63, SEC62, Structural Biology, Models, 2.1 Biological and endogenous factors, Molecular Biology, Protein Processing, Heat-Shock Proteins, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Endoplasmic reticulum, Post-Translational, Molecular, Membrane Transport Proteins, Eurotiales, Biological Sciences, biology.organism_classification, Transport protein, Cytosol, Protein Transport, Chemical Sciences, Generic health relevance, Infection, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, SEC Translocation Channels, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd7458d030b9e95da9a766df315e53c
http://europepmc.org/articles/PMC8236211

المؤلفون: Katie M. Kuo, David Ryoo, Karl Lundquist, James C. Gumbart

المصدر: Biophysical journal. 121(17)

مصطلحات موضوعية: Protein Folding, Escherichia coli Proteins, Gram-Negative Bacteria, Biophysics, Escherichia coli, Bacterial Outer Membrane Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3364782835f4ec6b546365eb867e039d
https://pubmed.ncbi.nlm.nih.gov/35927955

المؤلفون: Katie M. Kuo, Helen I. Zgurskaya, James C. Gumbart

المصدر: Biophysical Journal. 122:299a

مصطلحات موضوعية: Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dbfe32431c9c39ab9f6a51903abeff16
https://doi.org/10.1016/j.bpj.2022.11.1689

المؤلفون: Laura Rotolo, Daryll Vanover, Nicholas C. Bruno, Hannah E. Peck, Chiara Zurla, Jackelyn Murray, Richard K. Noel, Laura O’Farrell, Mariluz Araínga, Nichole Orr-Burks, Jae Yeon Joo, Lorena C. S. Chaves, Younghun Jung, Jared Beyersdorf, Sanjeev Gumber, Ricardo Guerrero-Ferreira, Santiago Cornejo, Merrilee Thoresen, Alicia K. Olivier, Katie M. Kuo, James C. Gumbart, Amelia R. Woolums, Francois Villinger, Eric R. Lafontaine, Robert J. Hogan, M. G. Finn, Philip J. Santangelo

المصدر: Nature materials.

مصطلحات موضوعية: Mechanics of Materials, Mechanical Engineering, General Materials Science, General Chemistry, Condensed Matter Physics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7ec4891651d0788c7b5a29165e8651
https://pubmed.ncbi.nlm.nih.gov/36443576

المؤلفون: Katie M. Kuo, David Ryoo, Karl Lundquist, James C. Gumbart

المصدر: Biophysical Journal. 121:465a-466a

مصطلحات موضوعية: Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47bccdbb63810cea0ede78ee619a41f2
https://doi.org/10.1016/j.bpj.2021.11.445

المؤلفون: Zijian Zhang, James C. Gumbart, Alexandra Atalis, Emily J. Devereaux, Randall Toy, Pallab Pradhan, Shohini Ghosh-Choudhary, Simran Dhal, Casey E. Vantucci, Nick J. Willett, Jinhwan Kim, Krishnendu Roy, Katie M. Kuo, Jiaying Liu, Jianguo Wen, Da Huo, Kelsey P. Kubelick, Stanislav Emelianov, Zhiheng Lyu, Younan Xia

المصدر: Nano Lett

مصطلحات موضوعية: medicine.drug_class, T cell, medicine.medical_treatment, Bioengineering, Janus particles, 02 engineering and technology, Multifunctional Nanoparticles, Monoclonal antibody, Article, Natural killer cell, Mice, Immune system, medicine, Animals, Humans, General Materials Science, Chemistry, Mechanical Engineering, Myeloid-Derived Suppressor Cells, Antibodies, Monoclonal, General Chemistry, Immunotherapy, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Cell biology, Rats, Killer Cells, Natural, medicine.anatomical_structure, Myeloid-derived Suppressor Cell, Nanoparticles, 0210 nano-technology, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9272a421da476aeca3cd33f8844f052
https://pubmed.ncbi.nlm.nih.gov/33395313

المؤلفون: Chi S. Sum, Christopher J. Butch, Lawrence J. Wilson, Katie M. Kuo, Michelle B. Kim, Yesim Altas Tahirovic, Mary Ellen Cvijic, Huy Nguyen, Dennis C. Liotta, Tao Wang, Robert Wilson, Valarie M. Truax, Eric J. Miller, Gretchen M. Schroeder, Edgars Jecs

المصدر: Journal of Medicinal Chemistry. 61:7168-7188

مصطلحات موضوعية: 0301 basic medicine, Receptors, CXCR4, Membrane permeability, T-Lymphocytes, Drug Evaluation, Preclinical, Pharmacology, 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP2D6 Inhibitors, Tetrahydroisoquinolines, Drug Discovery, Animals, Humans, Structure–activity relationship, Drug Interactions, Receptor, Cells, Cultured, ADME, Tetrahydroisoquinoline, Ligand (biochemistry), In vitro, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, chemistry, Drug Design, Microsomes, Liver, Molecular Medicine, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aa355fc7e64b8be28843fa21520a33
https://doi.org/10.1021/acs.jmedchem.8b00450

المؤلفون: Mary Ellen Cvijic, Katie M. Kuo, Chi S. Sum, Lawrence J. Wilson, Tao Wang, Yesim Altas Tahirovic, Valarie M. Truax, Eric J. Miller, Michelle B. Kim, Robert Wilson, Dennis C. Liotta, Gretchen M. Schroeder, Edgars Jecs, Huy Nguyen

المصدر: ACS Medicinal Chemistry Letters. 9:446-451

مصطلحات موضوعية: 0301 basic medicine, Benzimidazole, Tetrahydroisoquinoline, Organic Chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Piperazine, 030104 developmental biology, chemistry, Drug Discovery, Muscarinic acetylcholine receptor, Calcium flux, Side chain, Amine gas treating, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fb137ea8c246121b4acf7a962577b6
https://doi.org/10.1021/acsmedchemlett.8b00030

المؤلفون: Katie M. Kuo, Jinchan Liu, James C. Gumbart

المصدر: Biophysical Journal. 121:468a

مصطلحات موضوعية: Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1649ec98a3528099cde62098409b03dd
https://doi.org/10.1016/j.bpj.2021.11.459

المؤلفون: Chi S. Sum, Katie M. Kuo, Dennis C. Liotta, Tao Wang, Lawrence J. Wilson, Eric J. Miller, Brook M. Katzman, Gretchen M. Schroeder, Mary Ellen Cvijic, Edgars Jecs, Robert Wilson, Huy Nguyen, Valarie M. Truax, Michelle B. Kim, Yesim Altas Tahirovic

المصدر: ACS Medicinal Chemistry Letters. 9:89-93

مصطلحات موضوعية: 0301 basic medicine, Drug, CXCR4 Inhibitor, CXCR4 antagonist, Tetrahydroisoquinoline, Stereochemistry, media_common.quotation_subject, Organic Chemistry, Antagonist, Biochemistry, CXCR4, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Drug Discovery, Side chain, IC50, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37978d1c82bb13605d9185553329f15
https://doi.org/10.1021/acsmedchemlett.7b00406

المؤلفون: Robert Wilson, Michelle B. Kim, Edgars Jecs, Katie M. Kuo, Anthony A. Paiva, Dennis C. Liotta, Yesim Altas Tahirovic, Tao Wang, Huy Nguyen, Lawrence J. Wilson, Valarie M. Truax, Gretchen M. Schroeder, Mary Ellen Cvijic, Eric J. Miller, Chi Shing Sum

المصدر: ACS Medicinal Chemistry Letters. 9:17-22

مصطلحات موضوعية: 0301 basic medicine, Chemokine, biology, 010405 organic chemistry, Tetrahydroisoquinoline, Angiogenesis, Organic Chemistry, Chemotaxis, medicine.disease, 01 natural sciences, Biochemistry, CXCR4, 0104 chemical sciences, Metastasis, 03 medical and health sciences, chemistry.chemical_compound, Chemokine receptor, 030104 developmental biology, chemistry, Drug Discovery, Cancer cell, biology.protein, medicine, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a63b4e56550407b42f2c8d00cabfb8
https://doi.org/10.1021/acsmedchemlett.7b00381

المؤلفون: Luke P. Brewster, Sandeep Kumar, Chan Woo Kim, Rudolph L. Gleason, Sidd Dalal, Hanjoong Jo, Katie M. Kuo, Julia Raykin, Haiyan Li, Anastassia Pokutta-Paskaleva, Hiromi Yanagisawa, Andrew D. Morris, Tatiana Chadid, Lucas H. Timmins, Don-Won Kang

المصدر: Circulation. 136:1217-1232

مصطلحات موضوعية: Male, 0301 basic medicine, Aging, medicine.medical_specialty, Cardiovascular health, Receptor, Transforming Growth Factor-beta Type I, Down-Regulation, Protein Serine-Threonine Kinases, 030204 cardiovascular system & hematology, Article, Cell Line, Thrombospondin 1, Mice, 03 medical and health sciences, Vascular Stiffness, 0302 clinical medicine, Transforming Growth Factor beta, Physiology (medical), Internal medicine, RNA, Ribosomal, 18S, medicine, Shear stress, Animals, Humans, Cardiovascular mortality, Mice, Knockout, business.industry, Atrial Remodeling, Anatomy, medicine.disease, Immunohistochemistry, Stiffening, Mice, Inbred C57BL, Disease Models, Animal, Carotid Arteries, 030104 developmental biology, Arterial stiffness, Cardiology, Disturbed flow, Female, Collagen, Endothelium, Vascular, Shear Strength, Cardiology and Cardiovascular Medicine, business, Receptors, Transforming Growth Factor beta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd41dbca9af97ae026cb418cb6a2766
https://doi.org/10.1161/circulationaha.116.026361

المؤلفون: Zijian Zhang, Yui Tik Pang, David Ryoo, Katie M. Kuo, James C. Gumbart

المصدر: Biophysical Journal. 120:91a

مصطلحات موضوعية: Physics, Crystallography, Bama, Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::de2c1e9a9deb8e6bbb76192a54c31b4e
https://doi.org/10.1016/j.bpj.2020.11.762

المؤلفون: Edgars Jecs, Dennis C. Liotta, Eric J. Miller, Katie M. Kuo, Gretchen M. Schroeder, Manohar Saindane, Huy Nguyen, Huanyu Zhao, Robert Wilson, Mary Ellen Cvijic, Brooke M Katzman, Tao Wang, Lawrence J. Wilson, Chi S. Sum, Valarie M. Truax, Yesim Altas Tahirovic, Michelle B. Kim

المصدر: Journal of medicinal chemistry. 61(3)

مصطلحات موضوعية: 0301 basic medicine, Chemokine, Receptors, CXCR4, CXCR4, Intestinal absorption, Permeability, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Cytochrome P-450 CYP2D6 Inhibitors, Tetrahydroisoquinolines, Drug Discovery, Humans, Receptor, Tumor microenvironment, biology, Chemistry, Haematopoiesis, 030104 developmental biology, Absorption, Physicochemical, Cytochrome P-450 CYP2D6, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, biology.protein, Molecular Medicine, Stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e663423d25f58ab1e46b1fb7d16462bc
https://pubmed.ncbi.nlm.nih.gov/29350534

المؤلفون: Karl Lundquist, James C. Gumbart, Katie M. Kuo

المصدر: Biophysical Journal. 118:366a

مصطلحات موضوعية: Chemistry, Biophysics, Barrel (horology), Bacterial outer membrane, Biogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f703223236a0f0148c3221b7c72c49aa
https://doi.org/10.1016/j.bpj.2019.11.2102

المؤلفون: Tatiana Chadid, Katie M Kuo, Haiyan Li, Ian Copland, Luke P Brewster

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 35

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8575a28ca9cd2830092862bb7d78f4f4
https://doi.org/10.1161/atvb.35.suppl_1.193