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1
المؤلفون: Xingyue He, Mark G. Qian, Matthew O. Duffey, Larry Cohen, Michael D. Sintchak, Mi-Sook Kim, Jessica Riceberg, Vaishali Shindi, Kelly Connolly, Jianping Guo, Agatha Zawadzka, Rachel E. Gershman, Teresa A. Soucy, Neil Bence, Zhigen Hu, Xiaofeng Yang, Shumet A. Hailu, Nina Molchinova, Nanda Gulavita, Ji Zhang, Hirotake Mizutani, Keli Song, A D Patil, Scott Freeze, Jessica Grieves, Dylan Bradley England, Roushan Afroze, James J. Minissale, Anya Lublinsky, Mitsuhiro Ito, David Lok, Scott Weston Lane, William D. Mallender, Stephen Grossman, Kara Hoar, Nitya Durvasula, Bei-Ching Chuang, Yongbo Hu, Steven P. Langston, Sai M. Pulukuri, Miho Mizutani, Ryan Chau, Nancy Bump, Katherine M. Galvin, Christopher F. Claiborne, Paul D. Greenspan, He Xu, Gaulin Jeffrey L, Melissa Gallery, Douglas Bowman, Yana Wang, Koji Ono, Mcintyre Charles
المصدر: Journal of medicinal chemistry. 64(5)
مصطلحات موضوعية: Adenosine, SUMO protein, Antineoplastic Agents, Plasma protein binding, Ubiquitin-Activating Enzymes, 01 natural sciences, Adduct, 03 medical and health sciences, Mice, Structure-Activity Relationship, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Enzyme Inhibitors, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, Chemistry, Cancer, Sumoylation, medicine.disease, Xenograft Model Antitumor Assays, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cell culture, Covalent bond, Molecular Medicine, Sulfonic Acids, Protein Processing, Post-Translational, Protein Binding
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2Academic Journal
المؤلفون: David M. Margolis, Katherine M. Galvin, James R. Davie, Yang Shi, Jason J. Coull, Fabio Romerio, Jian-min Sun, Janet L
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.629.196; http://jvi.asm.org/content/74/15/6790.full.pdf
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3Academic Journal
المؤلفون: Mol Cell Biol, K M Galvin, Y Shi, Katherine M. Galvin, Yang Shi
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.627.7890; http://mcb.asm.org/content/17/7/3723.full.pdf
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4
المؤلفون: Emily F. Calderwood, Kathleen Aertgeerts, Michael D. Smith, Dylan Bradley England, Roushan Afroze, Ryan Chau, Stepan Vyskocil, Nancy E. Forsyth, Dong Mei Zhang, Ruth Adams, Stephen G. Stroud, O. P. Veiby, Christelle C. Renou, R. Scott Rowland, Erin Paske, Jane X. Liu, Ming Tregay, Michael D. Sintchak, Juliet A Williams, Shih-Chung Huang, Xu Tianlin, Bheemashankar Kulkarni, Sharmila Adhikari, Yuan Tian, Jason Yano, Christopher Blackburn, Paul D. Greenspan, Cheryl A. Farrer, Matthew O. Duffey, Liting Ma, Mi-Sook Kim, Qin Zhang, Sean Harrison, Hirotake Mizutani, Katherine M. Galvin, Alexandra E. Gould, Johnny J. Yang, Steven P. Langston, Dave Janowick, Natalia Iartchouk, Mansoureh Rezaei, Jeffery Gaulin, Khristofer Garcia, Hongbo Zeng, Ribo Guo, Tricia J. Vos, Jouhara Chouitar, Saurabh Menon
المصدر: Journal of Medicinal Chemistry. 54:1836-1846
مصطلحات موضوعية: Models, Molecular, Proto-Oncogene Proteins B-raf, Tetrahydronaphthalenes, Mutant, Melanoma, Experimental, Administration, Oral, Biological Availability, Mice, Nude, Antineoplastic Agents, Pharmacology, Crystallography, X-Ray, Mice, Structure-Activity Relationship, Pharmacokinetics, Mouse xenograft, In vivo, Drug Discovery, medicine, Animals, chemistry.chemical_classification, Chemistry, Melanoma, Stereoisomerism, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Bioavailability, Enzyme, Drug Design, Mutation, Molecular Medicine
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5
المؤلفون: Kristin E. Burke, Douglas Bowman, Arijit Chakravarty, Bradley Stringer, Katherine M. Galvin, Barbara Hibner
المصدر: High Content Screening: Science, Techniques and Applications
مصطلحات موضوعية: Chemistry, High-content screening, Pharmacodynamics, Pharmacology
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6
المؤلفون: Douglas Bowman, Jeffrey Ecsedy, John J. Hunter, Patrick J. LeRoy, Katherine M. Galvin, Kara Hoar, Vaishali Shinde, Jason Ruan, Krissy E. Burke
المصدر: Cancer Research. 67:5362-5370
مصطلحات موضوعية: Cancer Research, Molecular Sequence Data, Aurora A kinase, Aurora B kinase, Aurora inhibitor, Spindle Apparatus, macromolecular substances, Protein Serine-Threonine Kinases, Biology, Mice, Aurora Kinases, Serine, Animals, Humans, Amino Acid Sequence, Phosphorylation, Mitosis, Aurora Kinase A, Centrosome, Dose-Response Relationship, Drug, Benzazepines, HCT116 Cells, Xenograft Model Antitumor Assays, Cell biology, Spindle apparatus, enzymes and coenzymes (carbohydrates), Spindle checkpoint, Oncology, Colonic Neoplasms, embryonic structures, biological phenomena, cell phenomena, and immunity, HT29 Cells, Microtubule-Associated Proteins
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7
المؤلفون: David M. Margolis, Ulla Hansen, Katherine M. Galvin, James R. Davie, Janet Volker, Yang Shi, Jason J. Coull, Fabio Romerio, Jian-Min Sun
المصدر: Journal of Virology. 74:6790-6799
مصطلحات موضوعية: Gene Expression Regulation, Viral, Transcription, Genetic, Immunology, Repressor, Biology, Microbiology, Histone Deacetylases, Virology, medicine, Humans, Promoter Regions, Genetic, Psychological repression, Transcription factor, YY1 Transcription Factor, HIV Long Terminal Repeat, Virion, RNA-Binding Proteins, Molecular biology, Long terminal repeat, HDAC1, Virus-Cell Interactions, Cell biology, DNA-Binding Proteins, Trichostatin A, Insect Science, DNA, Viral, embryonic structures, HIV-1, Erythroid-Specific DNA-Binding Factors, Histone deacetylase, HeLa Cells, Transcription Factors, medicine.drug
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8
المؤلفون: Katherine M. Galvin, Victoria Fairchild-Huntress, Dean A. Falb, Judy H. Dunmore, John N. Lorenz, Michael J. Donovan, Michael A. Gimbrone, Kristen L. Dixon, Dennis Huszar, Richard J. Paul, Catherine A. Lynch, Ronald Meyer
المصدر: Nature Genetics. 24:171-174
مصطلحات موضوعية: Male, medicine.medical_specialty, Smad6 Protein, Recombinant Fusion Proteins, Cardiovascular Abnormalities, Restriction Mapping, Mice, Inbred Strains, Mice, Transgenic, SMAD, Biology, Bone morphogenetic protein, Cardiovascular System, Muscle, Smooth, Vascular, Mice, Endocardial cushion formation, Downregulation and upregulation, Internal medicine, Genetics, medicine, Animals, Homeostasis, Receptor, Mice, Knockout, Genomic Library, Mice, Inbred BALB C, R-SMAD, Homozygote, Cell biology, DNA-Binding Proteins, Mutagenesis, Insertional, Endocrinology, Trans-Activators, Female, Signal transduction, Signal Transduction
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9
المؤلفون: Katherine M. Galvin, Jing Wang, Raymond H. See, Jeng-Shin Lee, Yang Shi
المصدر: Nucleic Acids Research. 23:925-931
مصطلحات موضوعية: Transcription, Genetic, HMG-box, Protein Conformation, Recombinant Fusion Proteins, viruses, Repressor, Biology, Genetics, Humans, Amino Acid Sequence, Cyclic AMP Response Element-Binding Protein, Frameshift Mutation, Transcription factor, YY1 Transcription Factor, Sequence Deletion, Zinc finger transcription factor, Zinc finger, Activating Transcription Factor 2, DHR1 domain, DNA-binding domain, Molecular biology, Cell biology, DNA-Binding Proteins, embryonic structures, Erythroid-Specific DNA-Binding Factors, Adenovirus E1A Proteins, HeLa Cells, Transcription Factors, Binding domain
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10
المؤلفون: Paul D. Greenspan, Susan Chen, Liting Ma, Jane X. Liu, Johnny J. Yang, Qin Zhang, Ruth Adams, Shih-Chung Huang, Bheemashankar Kulkarni, Ryan W. Chau, Masayuki Nagayoshi, Matthew O. Duffey, Shaoxia Yu, Christopher Blackburn, Khristofer Garcia, Katherine M. Galvin, Tricia J. Vos, Sean Harrison, R. Scott Rowland, Xu Tianlin, Steven P. Langston, Mi-Sook Kim, Saurabh Menon, Alexandra E. Gould
المصدر: Bioorganicmedicinal chemistry letters. 20(16)
مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Stereochemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Pyrazoline, Pyrazoline derivatives, Non-specific serine/threonine protein kinase, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Computer Simulation, Molecular Biology, Protein Kinase Inhibitors, chemistry.chemical_classification, Binding Sites, biology, Organic Chemistry, Chemical modification, Thiophene derivatives, Recombinant Proteins, Enzyme, chemistry, Amino Acid Substitution, Enzyme inhibitor, biology.protein, Molecular Medicine, Pyrazoles
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11
المؤلفون: Bert H. O'Neil, Mark Manfredi, Howard A. Burris, Howard Fingert, Katherine M. Galvin, Omar Eton, E. Claire Dees, Jeffrey R. Infante, Bradley Stringer, Roger B. Cohen, Suzanne F. Jones, Margaret von Mehren, Hua Liu, Jeffrey Ecsedy, Yih Lee, Hadi Danaee
المصدر: Cancer chemotherapy and pharmacology. 67(4)
مصطلحات موضوعية: Adult, Male, Cancer Research, Maximum Tolerated Dose, Aurora inhibitor, Aurora A kinase, Administration, Oral, Antineoplastic Agents, Modafinil, Disorders of Excessive Somnolence, Pharmacology, Biology, Protein Serine-Threonine Kinases, Toxicology, medicine.disease_cause, Drug Administration Schedule, Article, Young Adult, Pharmacokinetics, Aurora Kinases, Neoplasms, medicine, Humans, Pharmacology (medical), In patient, Benzhydryl Compounds, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, Benzazepines, Middle Aged, Spindle apparatus, Oncology, Tumor progression, Maximum tolerated dose, Methylphenidate, Central Nervous System Stimulants, Female, Carcinogenesis, Half-Life
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12
المؤلفون: Katherine M. Galvin, Michael Seltzer
المصدر: Nonprofit and Voluntary Sector Quarterly. 20:249-266
مصطلحات موضوعية: Government, business.industry, 05 social sciences, Foundation (evidence), Public relations, medicine.disease, 0506 political science, Acquired immunodeficiency syndrome (AIDS), Political science, 0502 economics and business, 050602 political science & public administration, medicine, business, 050203 business & management, Social Sciences (miscellaneous)
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13
المؤلفون: Mark G. Manfredi, Jeffrey A. Ecsedy, Kristan A. Meetze, Suresh K. Balani, Olga Burenkova, Wei Chen, Katherine M. Galvin, Kara M. Hoar, Jessica J. Huck, Patrick J. LeRoy, Emily T. Ray, Todd B. Sells, Bradley Stringer, Stephen G. Stroud, Tricia J. Vos, Gabriel S. Weatherhead, Deborah R. Wysong, Mengkun Zhang, Joseph B. Bolen, Christopher F. Claiborne
مصطلحات موضوعية: Male, Aurora inhibitor, Aurora B kinase, Aurora A kinase, Administration, Oral, Mice, Nude, Antineoplastic Agents, Tumor initiation, Biology, Pharmacology, Protein Serine-Threonine Kinases, Inhibitory Concentration 50, Mice, Aurora kinase, Aurora Kinases, Cell Line, Tumor, Animals, Aurora Kinase B, Humans, Enzyme Inhibitors, Aurora Kinase A, Multidisciplinary, Dose-Response Relationship, Drug, Biological Sciences, Benzazepines, Apoptosis, Disease Progression, Female, Neoplasm Transplantation
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14
المؤلفون: Eric S. Lander, Clifford J. Tabin, Monte Westerfield, Deborah J. Goff, Katherine M. Galvin, Hillary Katz
المصدر: Genomics. 14:200-202
مصطلحات موضوعية: Genetics, Polymorphism, Genetic, Base Sequence, Molecular Sequence Data, Computational biology, Biology, biology.organism_classification, Polymerase Chain Reaction, Genome, Genetic marker, Multigene Family, Animals, Microsatellite, Identification (biology), Repeated sequence, Zebrafish, Organism, Genomic organization
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15
المؤلفون: Katherine M. Galvin, Yang Shi
المصدر: Molecular and cellular biology. 17(7)
مصطلحات موضوعية: Transcription, Genetic, Sp1 Transcription Factor, Repressor, Biology, DNA-binding protein, Structure-Activity Relationship, Coactivator, Humans, Cyclic AMP Response Element-Binding Protein, Molecular Biology, Transcription factor, Psychological repression, YY1 Transcription Factor, Genetics, Zinc finger, Sp1 transcription factor, YY1, Nuclear Proteins, Zinc Fingers, Cell Biology, DNA-Binding Proteins, Repressor Proteins, NFI Transcription Factors, embryonic structures, CCAAT-Enhancer-Binding Proteins, Trans-Activators, Erythroid-Specific DNA-Binding Factors, HeLa Cells, Transcription Factors, Research Article
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16
المؤلفون: Katherine M. Galvin, Yang Shi, Jeng-Shin Lee
المصدر: Biochimica et biophysica acta. 1332(2)
مصطلحات موضوعية: Cancer Research, Co repressor, YY1 Transcription Factor, Transcription, Genetic, Art history, Down-Regulation, Biology, YIN-YANG-1, DNA-Binding Proteins, Oncology, Gene Expression Regulation, Genetics, Viral latency, Animals, Erythroid-Specific DNA-Binding Factors, Humans, Promoter Regions, Genetic, Co activator, Transcription Factors
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17
المؤلفون: Andamy S. Lee, Yuchu Hsiung, Katherine M. Galvin, Victor K. Wong, Wilfred W. Li, Yang Shi, Yanhong Zhou
مصطلحات موضوعية: Transcriptional Activation, Recombinant Fusion Proteins, Molecular Sequence Data, DNA, Single-Stranded, Biology, Transfection, DNA-binding protein, Bacterial Proteins, Transcription (biology), Heat shock protein, Humans, Cloning, Molecular, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, YY1 Transcription Factor, Ccaat-enhancer-binding proteins, Serine Endopeptidases, Nuclear Proteins, Promoter, Cell Biology, Sequence Analysis, DNA, Y box binding protein 1, Cold-shock domain, Molecular biology, Cell biology, Cold Temperature, DNA-Binding Proteins, NFI Transcription Factors, CCAAT-Enhancer-Binding Proteins, Erythroid-Specific DNA-Binding Factors, Y-Box-Binding Protein 1, Carrier Proteins, Research Article, HeLa Cells, Molecular Chaperones, Transcription Factors
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18
المؤلفون: Stephanie Faucette, Katherine M. Galvin, Mayank Patel, Xiaofei Zhou, Viviana Bozon, Jerome T. Mettetal, Michael Bargfrede, Jouhara Chouitar, Karthik Venkatakrishnan
المصدر: Molecular Cancer Therapeutics. 12:A215-A215
مصطلحات موضوعية: Cancer Research, education.field_of_study, Chemistry, Population, Pharmacology, NONMEM, Oncology, Pharmacokinetics, Free fraction, Pharmacodynamics, education, IC50, PK/PD models, EC50
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19
المؤلفون: Kurt Eng, Mike Kuranda, Steve Stroud, Masanori Okaniwa, Robyn Fabrey, Kazuhide Nakamura, Saurabh Menon, Patrick Vincent, Elizabeth Grace Carideo Cunniff, Teena Vagrhese, Katherine M. Galvin, Julie Zhang, Takeo Arita, Khristofer Garcia, Jerome T. Mettetal, Deanna Borelli, Akito Nakamura, Sei Yoshida, Tomoyasu Ishikawa, Jouhara Chouitar
المصدر: Molecular Cancer Therapeutics. 12:C146-C146
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Kinase, business.industry, Colorectal cancer, Melanoma, MEK inhibitor, Mutant, Cancer, Raf Kinase Inhibitor, Pharmacology, medicine.disease, Oncology, Cancer research, medicine, business
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20
المؤلفون: Masanori Okaniwa, Robyn Fabrey, Patrick Vincent, Takeo Arita, Mike Kuranda, Deanna Borrelli, Akito Nakamura, Kurt Eng, Saurabh Menon, Kazuhide Nakamura, Julie Zhang, Steve Stroud, Khristofer Garcia, Jerome T. Mettetal, Katherine M. Galvin, Teena Vagrhese, Jouhara Chouitar, Tomoyasu Ishikawa, Elizabeth Grace Carideo Cunniff, Sei Yoshida
المصدر: Journal of Clinical Oncology. 31:e13529-e13529
مصطلحات موضوعية: Cancer Research, Kinase, business.industry, Colorectal cancer, Melanoma, Mutant, Raf Kinase Inhibitor, medicine.disease, Combined treatment, Oncology, Cancer research, Medicine, business, neoplasms