المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L Harris, Karl J Morten, Francesca M Buffa

المصدر: PLoS Computational Biology, Vol 20, Iss 3, p e1011944 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011944&type=printable; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/0eb01951447743aaa95598c797984cf8

المؤلفون: Karl J Morten, Michelle Potter, Luned Badder, Pamela Sivathondan, Rebecca Dragovic, Abigale Neumann, James Gavin, Roshan Shrestha, Svetlana Reilly, Kanchan Phadwal, Tiffany A. Lodge, Angela Borzychowski, Sharon Cookson, Corey Mitchell, Alireza Morovat, Anna Katharina Simon, Johanna Uusimaa, James Hynes, Joanna Poulton

المصدر: Wellcome Open Research, Vol 2 (2019)

مصطلحات موضوعية: pancreas, Medicine, Science

وصف الملف: electronic resource

Relation: https://wellcomeopenresearch.org/articles/2-14/v3; https://doaj.org/toc/2398-502X

URL الوصول: https://doaj.org/article/fe13c9ee59e34f6b87ed8a15400ee82f

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/S4_Fig_-/25420548

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s008

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Multi-scale_modelling_framework_/25420539

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s005

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/sigQC_metrics_were_calculated_for_our_network_genes_in_TCGA_and_CCLE_breast_cancer_RNA_Seq_datasets_/25420554

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s010

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Methodology_and_Parameters_/25420527

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s001

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/The_cell_regulatory_network_of_our_model_microC_model_/25420542

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s006

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Different_time_scales_are_used_for_different_processes_/25420545

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s007

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Dynamics_of_total_glycolytic_glycoATP_and_OXPHOS_mitoATP_cell_populations_over_time_under_different_application_strategies_of_MCT1_and_GLUT1_inhibitors_/25420578

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s018

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Metabolic_symbiotic_simulations_with_network_gene_alterations_Enriched_and_Knockout_-_status_and_wild_type_WT_status_/25420557

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s011

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Symbiosis-induced_changes_of_glucose_and_oxygen_of_the_microenvironment_over_time_/25420560

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s012

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_curves_are_shown_for_different_combinations_of_oxygen_and_glucose_/25420566

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s014

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_over_time_at_different_combinations_of_GLUT1_and_MCT1_inhibitors_/25420572

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s016

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_under_different_environmental_conditions_different_levels_of_glucose_lactate_and_oxygen_are_shown_for_p53wt_and_p53-_cells_/25420563

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s013

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/The_effect_of_half-saturation_coefficients_of_oxygen_and_glucose_on_the_metabolic_pathways_is_shown_/25420569

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s015

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/MCT1_and_GLUT1_inhibition_/25420575

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s017

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Partial_correlation_coefficients_between_symbiosis-induced_growth_increment_of_tumour_and_model_parameters_over_time_/25420584

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s020

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Partial_correlation_coefficients_between_model_parameters_and_outputs_over_time_/25420581

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s019

المؤلفون: Sławomir Kujawski, Joanna Słomko, Karl J. Morten, Modra Murovska, Katarzyna Buszko, Julia L. Newton, Paweł Zalewski

المصدر: Medicina, Vol 60, Iss 2, p 255 (2024)

مصطلحات موضوعية: n/a, Medicine (General), R5-920

Relation: https://www.mdpi.com/1648-9144/60/2/255; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144; https://doaj.org/article/d41b6036106b43a2b075a0a0dcf7e48a

الاتاحة: https://doi.org/10.3390/medicina60020255
https://doaj.org/article/d41b6036106b43a2b075a0a0dcf7e48a

المؤلفون: Jiabao Xu, Tiffany Lodge, Caroline Kingdon, James W. L. Strong, John Maclennan, Eliana Lacerda, Slawomir Kujawski, Pawel Zalewski, Wei E. Huang, Karl J. Morten

المصدر: Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)

مصطلحات موضوعية: machine learning, mitochondria, multiple sclerosis, myalgic encephalomyelitis/chronic fatigue syndrome, peripheral blood mononuclear cells, Raman microspectroscopy, Science

Relation: https://doi.org/10.1002/advs.202302146; https://doaj.org/toc/2198-3844; https://doaj.org/article/e64e3d5fa7774b50b117e525bc11f7a5

الاتاحة: https://doi.org/10.1002/advs.202302146
https://doaj.org/article/e64e3d5fa7774b50b117e525bc11f7a5