المؤلفون: Saumya Maheshwari, In Hwa Um, Struan Donachie, Nafeesa Asghar, Karina McDade, Tracey Millar, David J. Harrison, Javier A. Tello

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

مصطلحات موضوعية: Stroke, Intracerebral haemorrhage, ICH, Kisspeptin, Biomarker, Cerebral amyloid angiopathy, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/1399c9a1d03c45268e641fdaa457b1c9

المؤلفون: Zoeb Jiwaji, Sachin S. Tiwari, Rolando X. Avilés-Reyes, Monique Hooley, David Hampton, Megan Torvell, Delinda A. Johnson, Jamie McQueen, Paul Baxter, Kayalvizhi Sabari-Sankar, Jing Qiu, Xin He, Jill Fowler, James Febery, Jenna Gregory, Jamie Rose, Jane Tulloch, Jamie Loan, David Story, Karina McDade, Amy M. Smith, Peta Greer, Matthew Ball, Peter C. Kind, Paul M. Matthews, Colin Smith, Owen Dando, Tara L. Spires-Jones, Jeffrey A. Johnson, Siddharthan Chandran, Giles E. Hardingham

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3684566e972d48bda37be69378c00e42

المؤلفون: Colin Smith, Rustam Al-Shahi Salman, Karina McDade, Edward Christopher, Neshika Samarasekera, James J M Loan, Jamie Rose, Jack Barrington, Jeremy Hughes

المصدر: BMJ Neurology Open, Vol 4, Iss 1 (2022)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://neurologyopen.bmj.com/content/4/1/e000238.full; https://doaj.org/toc/2632-6140

URL الوصول: https://doaj.org/article/3cfe53a053a74e8583f76664a1754f3e

المؤلفون: Samantha K. Barton, Jenna M. Gregory, Bhuvaneish T. Selvaraj, Karina McDade, Christopher M. Henstridge, Tara L. Spires-Jones, Owen G. James, Arpan R. Mehta, David Story, Karen Burr, Dario Magnani, Adrian M. Isaacs, Colin Smith, Siddharthan Chandran

المصدر: Frontiers in Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: oligodendrocytes, RNA trafficking, myelination, ALS, myelin basic protein, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.705306/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/b45e0692110c4e06a184d5b851be4204

المؤلفون: Jenna M. Gregory, Daniel R. Whiten, Rebecca A. Brown, Teresa P. Barros, Janet R. Kumita, Justin J. Yerbury, Sandeep Satapathy, Karina McDade, Colin Smith, Leila M. Luheshi, Christopher M. Dobson, Mark R. Wilson

المصدر: Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: TDP-43, Cytoplasmic inclusions, Proteotoxicity, Chaperone translocation, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-017-0481-1; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/21bc7900713e4ebdb657794a389341be

المؤلفون: Poulomi Banerjee, Arpan R. Mehta, Raja S. Nirujogi, James Cooper, Owen G. James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R. Alessi, Bhuvaneish T. Selvaraj, Josef Priller, Siddharthan Chandran

المصدر: Science advances 9(16), eabq0651 (2023). doi:10.1126/sciadv.abq0651
Banerjee, P, Mehta, A, Nirujogi, R S, Cooper, J, James, O G, Nanda, J, Longden, J, Burr, K, McDade, K, Salzinger, A, Paza, E, Newton, J, Story, D, Pal, S, Smith, C, Alessi, D R, Thangaraj Selvaraj, B, Priller, J & Chandran, S 2023, ' Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration ', Science Advances . https://doi.org/10.1126/sciadv.abq0651

مصطلحات موضوعية: Multidisciplinary, ddc:500

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffe9b8361917d07a830b67f50046784
https://pub.dzne.de/record/257688

المؤلفون: Alexander Haglund, Verena Zuber, Yifei Yang, Maya Abouzeid, Rahel Feleke, Jeong Hun Ko, Alexi Nott, Ann C. Babtie, James D. Mills, Louwai Muhammed, Liisi Laaniste, Djordje O. Gveric, Daniel Clode, Susanna Pagni, Ravishankara Bellampalli, Alyma Somani, Karina McDade, Jasper J. Anink, Lucia Mesarosova, Eleonora Aronica, Maria Thom, Sanjay M. Sisodiya, Prashant K. Srivastava, Dheeraj Malhotra, Julien Bryois, Leonardo Bottolo, Michael R. Johnson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b1427c4abdeae3047a989d38ab0eea78
https://doi.org/10.1101/2022.11.28.517913

المؤلفون: Arpan R. Mehta, Karina McDade, Judith Newton, Marc-David Ruepp, Suvankar Pal, Siddharthan Chandran, Colin Smith, Bhuvaneish T. Selvaraj

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17ad522b3f14ff2056cb398e353fff09
https://doi.org/10.1101/2022.09.01.22279305

المؤلفون: Olivia M Rifai, James Longden, Judi O'Shaughnessy, Michael DE Sewell, Judith Pate, Karina McDade, Michael JD Daniels, Sharon Abrahams, Siddharthan Chandran, Barry W McColl, Christopher R Sibley, Jenna M Gregory

المصدر: Rifai, O M, Longden, J, O'Shaughnessy, J, Sewell, M D E, Pate, J, McDade, K, Daniels, M J D, Abrahams, S, Chandran, S, McColl, B W, Sibley, C R & Gregory, J M 2022, ' Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS ', The Journal of Pathology, vol. 258, no. 4, pp. 366-381 . https://doi.org/10.1002/path.6008

مصطلحات موضوعية: amyotrophic lateral sclerosis, C9orf72 Protein, TDP-43, Amyotrophic Lateral Sclerosis, microglia, frontotemporal dementia, neuroinflammation, Pathology and Forensic Medicine, machine learning, Frontotemporal Dementia, C9orf72, Mutation, Humans, Microglia, digital pathology, post-mortem tissue, FUS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d55e3013108500a0c42857e686b4ad4
https://pubmed.ncbi.nlm.nih.gov/36070099

المؤلفون: David Story, Karen Burr, Roderick N. Carter, Arpan R Mehta, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Colin Smith, Jenna M. Gregory, Giles E. Hardingham, Nicholas M. Morton, Don J. Mahad, Owen Dando, Karina McDade, Jyoti Nanda

المصدر: Mehta, A R, Gregory, J M, Dando, O, Carter, R N, Burr, K, Nanda, J, Story, D, Mcdade, K, Smith, C, Morton, N M, Mahad, D J, Hardingham, G E, Chandran, S & Selvaraj, B T 2021, ' Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis ', Acta Neuropathologica . https://doi.org/10.1007/s00401-020-02252-5
Acta Neuropathologica

مصطلحات موضوعية: Adult, Male, Motor neuron, Mitochondrial DNA, Induced Pluripotent Stem Cells, Gene Dosage, Mitochondrion, Biology, Axon, Pathology and Forensic Medicine, Electron Transport, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, C9orf72, medicine, Homeostasis, Humans, Neurodegeneration, Amyotrophic lateral sclerosis, Aged, 030304 developmental biology, Motor Neurons, Original Paper, 0303 health sciences, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Energy metabolism, Middle Aged, medicine.disease, Axons, Mitochondria, Cell biology, Posterior Horn Cells, medicine.anatomical_structure, Gene Expression Regulation, nervous system, Mitochondrial biogenesis, Female, Neurology (clinical), Frontotemporal dementia, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbc73ad975fbf9d387a95cbaa104da6
https://doi.org/10.1007/s00401-020-02252-5

المؤلفون: Olivia M. Rifai, James Longden, Judi O’Shaughnessy, Michael D.E. Sewell, Karina McDade, Michael J.D. Daniels, Sharon Abrahams, Siddharthan Chandran, Barry McColl, Christopher R. Sibley, Jenna M. Gregory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6ac71fb27c9e3f5b2f54232833b625af
https://doi.org/10.1101/2021.12.10.471808

المؤلفون: Poulomi Banerjee, Elizabeth Elliott, Olivia M Rifai, Judi O’Shaughnessy, Karina McDade, Sharon Abrahams, Siddharthan Chandran, Colin Smith, Jenna M Gregory

المصدر: Banerjee, P, Elliott, E, Rifai, O, O'shaughnessy, J, Mcdade, K, Abrahams, S, Chandran, S, Smith, C & Gregory, J M 2021, ' NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis ', The Journal of Pathology . https://doi.org/10.1002/path.5846

مصطلحات موضوعية: Cognition, Inflammasomes, Gene Expression Profiling, Amyotrophic Lateral Sclerosis, NLR Family, Pyrin Domain-Containing 3 Protein, Brain, Humans, Cognitive Dysfunction, Resilience, Psychological, Transcriptome, Pathology and Forensic Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b86186c0c8f84531f74ec68924cc0ab
https://pubmed.ncbi.nlm.nih.gov/35342958

المؤلفون: Timothy J. Aitman, Siddharthan Chandran, S. Marion de Proce, Karina McDade, Jenna M. Gregory, Colin Smith, I. Croy, Matthew R. Livesey

المصدر: Gregory, J M, McDade, K, Livesey, M R, Croy, I, Marion de Proce, S, Aitman, T, Chandran, S & Smith, C 2020, ' Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis ', Neuropathology and Applied Neurobiology, vol. 46, no. 5, pp. 441-457 . https://doi.org/10.1111/nan.12597

مصطلحات موضوعية: Male, 0301 basic medicine, Cell type, Histology, SOD1, In situ hybridization, Biology, Pathology and Forensic Medicine, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, C9orf72, Physiology (medical), medicine, Humans, Receptors, AMPA, Amyotrophic lateral sclerosis, DNA Repeat Expansion, Histocytological Preparation Techniques, C9orf72 Protein, Sequence Analysis, RNA, Molecular pathology, Gene Expression Profiling, Amyotrophic Lateral Sclerosis, Brain, Middle Aged, medicine.disease, 030104 developmental biology, Spinal Cord, Neurology, Female, Autopsy, Ubiquitin-Specific Proteases, Neurology (clinical), Trinucleotide repeat expansion, Ubiquitin Thiolesterase, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adb72db43045a3010b9d6a4e6c07f9e
https://doi.org/10.1111/nan.12597

المؤلفون: Karina McDade, Jenna M. Gregory, Bhuvaneish T. Selvaraj, Matthew R. Livesey, Siddharthan Chandran, Colin Smith, Samantha K. Barton

المصدر: The Journal of Pathology
Gregory, J M, Livesey, M R, Mcdade, K, Selvaraj, B T, Barton, S K, Chandran, S & Smith, C 2019, ' Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain ', Journal of Pathology, vol. 250, no. 1, pp. 67-78 . https://doi.org/10.1002/path.5351

مصطلحات موضوعية: Male, 0301 basic medicine, AMPAR, Superoxide Dismutase-1, 0302 clinical medicine, C9orf72, Amyotrophic lateral sclerosis, Motor Neurons, education.field_of_study, Brain, SOD1, Middle Aged, Original Papers, medicine.anatomical_structure, Receptors, Glutamate, Spinal Cord, 030220 oncology & carcinogenesis, Female, Autopsy, Motor cortex, Induced Pluripotent Stem Cells, Population, BaseScope, Biology, Cell Line, Pathology and Forensic Medicine, 03 medical and health sciences, post‐mortem, medicine, Humans, Genetic Predisposition to Disease, Receptors, AMPA, education, Aged, Original Paper, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Motor neuron, medicine.disease, neuron, 030104 developmental biology, Gene Expression Regulation, nervous system, Case-Control Studies, sporadic, Mutation, RNA, Neuron, ALS, Trinucleotide repeat expansion, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32dcae21a2efc2c38c8d14a172b53cf
https://doi.org/10.1002/path.5351

المؤلفون: Colin Smith, Siddharthan Chandran, Suvankar Pal, Thomas H. Bak, Jenna M. Gregory, Karina McDade, Sharon Abrahams

المصدر: Gregory, J, McDade, K, Bak, T, Pal, S, Chandran, S, Smith, C & Abrahams, S 2020, ' Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS ', Journal of Neurology, Neurosurgery & Psychiatry, vol. 91, no. 2, pp. 149-157 . https://doi.org/10.1136/jnnp-2019-320807
Journal of Neurology, Neurosurgery, and Psychiatry

مصطلحات موضوعية: Male, cognition, medicine.medical_specialty, TDP-43, Neuropathology, Neuropsychological Tests, Audiology, Executive Function, 03 medical and health sciences, Fluency, 0302 clinical medicine, medicine, Humans, Dementia, Verbal fluency test, Cognitive Dysfunction, Neurodegeneration, Amyotrophic lateral sclerosis, 030304 developmental biology, Cerebral Cortex, Language Disorders, neuropathology, 0303 health sciences, Verbal Behavior, business.industry, Amyotrophic Lateral Sclerosis, Cognition, Middle Aged, ECAS, medicine.disease, Executive functions, Cognitive test, DNA-Binding Proteins, Psychiatry and Mental health, Female, Surgery, Neurology (clinical), ALS, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d31793b8826c619dbaa20d70b19bfe4
https://doi.org/10.1136/jnnp-2019-320807

المؤلفون: Siddharthan Chandran, Elizabeth Elliott, Suvankar Pal, Thomas H. Bak, Jenna M. Gregory, Karina McDade, Sharon Abrahams, Colin Smith

المصدر: Neuropathology and Applied Neurobiology
Gregory, J M, Elliot, E, Mcdade, K, Bak, T, Pal, S, Chandran, S, Abrahams, S & Smith, C 2019, ' Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis ', Neuropathology and Applied Neurobiology . https://doi.org/10.1111/nan.12575

مصطلحات موضوعية: 0301 basic medicine, cognition, Male, Histology, neuropatholofy, TDP-43, Cell, Neuropathology, In situ hybridization, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Physiology (medical), Medicine, Humans, Cognitive Dysfunction, Amyotrophic lateral sclerosis, Pathological, Neurons, neuropathology, Clusterin, biology, business.industry, Amyotrophic Lateral Sclerosis, Brain, Original Articles, ECAS, Middle Aged, medicine.disease, DNA-Binding Proteins, TDP‐43, 030104 developmental biology, Proteostasis, medicine.anatomical_structure, Neurology, biology.protein, Original Article, Female, Neurology (clinical), ALS, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60ec9d6db4e9799a578331bac324c7f
http://europepmc.org/articles/PMC7318312

المؤلفون: Elizabeth Elliott, Jenna M Gregory, Owen Dando, Karina McDade, Colin Smith, Siddharthan Chandran

المصدر: Journal of Neurology, Neurosurgery & Psychiatry. 93:A3.2-A3

مصطلحات موضوعية: Psychiatry and Mental health, Surgery, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c1e290ad49d25e437272dc0bd986f165
https://doi.org/10.1136/jnnp-2022-abn.8

المؤلفون: Samantha K. Barton (11369952), Jenna M. Gregory (7478666), Bhuvaneish T. Selvaraj (8998664), Karina McDade (4578235), Christopher M. Henstridge (10259461), Tara L. Spires-Jones (9176741), Owen G. James (11369955), Arpan R. Mehta (10259458), David Story (2308), Karen Burr (510199), Dario Magnani (175697), Adrian M. Isaacs (8572119), Colin Smith (6343), Siddharthan Chandran (94755)

مصطلحات موضوعية: Neuroscience, Biological Engineering, Developmental Biology, Stem Cells, Artificial Intelligence and Image Processing, Endocrinology, Radiology and Organ Imaging, Autonomic Nervous System, Cellular Nervous System, Central Nervous System, Sensory Systems, Clinical Nursing: Tertiary (Rehabilitative), Decision Making, Rehabilitation Engineering, Biomedical Engineering not elsewhere classified, Signal Processing, Neurogenetics, Image Processing, oligodendrocytes, RNA trafficking, myelination, ALS, myelin basic protein

Relation: https://figshare.com/articles/figure/Image_1_Dysregulation_in_Subcellular_Localization_of_Myelin_Basic_Protein_mRNA_Does_Not_Result_in_Altered_Myelination_in_Amyotrophic_Lateral_Sclerosis_TIFF/16552263

الاتاحة: https://doi.org/10.3389/fnins.2021.705306.s001

المؤلفون: Jenna M. Gregory, Karina McDade, Siddharthan Chandran, Arpan R Mehta, Samantha K. Barton, Bhuvaneish T. Selvaraj, Colin Smith, Sharon Abrahams

المصدر: Brain communications
Mehta, A R, Selvaraj, B T, Barton, S K, Mcdade, K, Abrahams, S, Chandran, S, Smith, C & Gregory, J M 2020, ' Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction ', Brain Communications, vol. 2, no. 1, fcaa009 . https://doi.org/10.1093/braincomms/fcaa009

مصطلحات موضوعية: cognition, 0301 basic medicine, Pathology, medicine.medical_specialty, Cell type, TDP-43, sense RNA foci, In situ hybridization, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, C9orf72, Sense (molecular biology), medicine, Amyotrophic lateral sclerosis, antisense RNA foci, General Engineering, RNA, Spinal cord, medicine.disease, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, ALS, Trinucleotide repeat expansion, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed885757c8f80d35254e180cb7a9bbc
https://doi.org/10.1093/braincomms/fcaa009

المؤلفون: Maureen M. Bain, Daoqing Gong, Peter W.F. Wilson, Karina McDade, Yves Nys, Jiri Kalina, Virginie Hervé-Grépinet, Ian C. Dunn

المساهمون: University of Edinburgh, Yangzhou University, Faculty of Veterinary Medicine, University of Glasgow, Unité de Recherches Avicoles (URA), Institut National de la Recherche Agronomique (INRA)

المصدر: BMC Immunology
BMC Immunology, BioMed Central, 2010, 11, pp.1-15. ⟨10.1186/1471-2172-11-12⟩
BMC Immunology, Vol 11, Iss 1, p 12 (2010)
BMC Immunology (11), 1-15. (2010)
Gong, D, Wilson, P W, Bain, M M, McDade, K, Kalina, J, Herve-Grepinet, V, Nys, Y & Dunn, I C 2010, ' Gallin; an antimicrobial peptide member of a new avian defensin family, the ovodefensins, has been subject to recent gene duplication ', BMC Immunology, vol. 11, 12, pp.-. https://doi.org/10.1186/1471-2172-11-12

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, beta-Defensins, animal structures, expression génique, [SDV]Life Sciences [q-bio], Amino Acid Motifs, Immunology, Egg protein, Oviducts, Biology, Evolution, Molecular, 03 medical and health sciences, Anti-Infective Agents, Gene Duplication, Research article, Gene duplication, Animals, [INFO]Computer Science [cs], Defensin, Gene, Phylogeny, 030304 developmental biology, Genetics, 0303 health sciences, Innate immune system, blanc d'oeuf, gène, Egg Proteins, 030302 biochemistry & molecular biology, Computational Biology, poule, gallus domesticus, Antimicrobial, Immunity, Innate, protéine antimicrobienne, volaille, Beta defensin, Xanthenes, protéine, Multigene Family, oeuf, Female, lcsh:RC581-607, Chickens, Egg white

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27a246ada4ab8087b6f662c0827ec7e