المؤلفون: Tom D Deegan, Progya P Mukherjee, Ryo Fujisawa, Cristian Polo Rivera, Karim Labib

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: DNA replication, termination, CMG helicase, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/60371; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/6c8161f617dc48f6bb5652e3e06dc23f

المؤلفون: Ye Hong, Remi Sonneville, Bin Wang, Viktor Scheidt, Bettina Meier, Alexander Woglar, Sarah Demetriou, Karim Labib, Verena Jantsch, Anton Gartner

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1e006c13ac23401faf2de36c69fca25c

المؤلفون: Marija Maric, Progya Mukherjee, Michael H. Tatham, Ronald Hay, Karim Labib

المصدر: Cell Reports, Vol 18, Iss 13, Pp 3033-3042 (2017)

مصطلحات موضوعية: CMG helicase, DNA replication termination, Cdc48, Ufd1-Npl4, ubiquitylation, ubiquitin, replisome, disassembly, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717303376; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/321274dabc7841daabeab2f9a61d2f35

المؤلفون: Remi Sonneville, Rahul Bhowmick, Saskia Hoffmann, Niels Mailand, Ian D Hickson, Karim Labib

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: DNA replication, genome stability, ubiquitin ligase, TRAIP, mitosis, fragile site, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/48686; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/7a4bbbba579a45c4a2b6bfe82441f165

المؤلفون: Ye Hong, Maria Velkova, Nicola Silva, Marlène Jagut, Viktor Scheidt, Karim Labib, Verena Jantsch, Anton Gartner

المصدر: PLoS Genetics, Vol 14, Iss 6, p e1007453 (2018)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/64caa845417046a49b92c42a3a4e1320

المؤلفون: Remi Sonneville, Gillian Craig, Karim Labib, Anton Gartner, J. Julian Blow

المصدر: Cell Reports, Vol 12, Iss 3, Pp 405-417 (2015)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124715006580; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/fe58d21069a64a398a313e57cc81a872

المؤلفون: Magdalena Foltman, Cecile Evrin, Giacomo De Piccoli, Richard C. Jones, Rick D. Edmondson, Yuki Katou, Ryuichiro Nakato, Katsuhiko Shirahige, Karim Labib

المصدر: Cell Reports, Vol 3, Iss 3, Pp 892-904 (2013)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713001046; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/4b4f4cc7789e4b009e9983ada1d5177c

المؤلفون: Raymond Buser, Vanessa Kellner, Andre Melnik, Caroline Wilson-Zbinden, René Schellhaas, Lisa Kastner, Wojciech Piwko, Martina Dees, Paola Picotti, Marija Maric, Karim Labib, Brian Luke, Matthias Peter

المصدر: PLoS Genetics, Vol 12, Iss 2, p e1005843 (2016)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4743919?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/110d152626304cb6aa16c4e593d316c1

المؤلفون: Md Ariful Haque, Liton Baroi, Ismat Ara Chowdhury Koly, Md Shakibul Hasan, Faiza Mahmud, Sifat Ara Eva, Moinul Karim Labib, Hazika Tuz-Zohura Nafisa, Salwa Islam, Irfat Islam Eva, Md. Rafiqul Islam, Lita Bose, Faming Tian

المصدر: Bulletin of Faculty of Physical Therapy, Vol 29, Iss 1, Pp 1-10 (2024)

مصطلحات موضوعية: BlackBerry thumb, De Quervain disease, Smartphone, Android phone, University students, Bangladesh, Miscellaneous systems and treatments, RZ409.7-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2536-9660

URL الوصول: https://doaj.org/article/1069fa6fa8dd4b8e8318166cf9d1c131

المؤلفون: Pedro Junior Nkosi, Bianca-Sabrina Targosz, Karim Labib, Alberto Sanchez-Diaz

المصدر: PLoS ONE, Vol 8, Iss 2, p e57846 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3585203?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/f70c7c38746c421caa38601e36738bb8

المؤلفون: Tom D Deegan, Karim Labib, Giuseppe Cannone, Michael Jenkyn-Bedford, Joseph T.P. Yeeles, Yasemin Baris, Morgan L. Jones

المساهمون: Jenkyn-Bedford, Michael [0000-0003-2335-8278], Jones, Morgan L [0000-0003-1948-4925], Yeeles, Joseph TP [0000-0002-2255-2119], Deegan, Tom D [0000-0001-9639-7636], Apollo - University of Cambridge Repository

المصدر: Nature
Jenkyn-Bedford, M, Jones, M L, Baris, Y, Labib, K P M, Cannone, G, Yeeles, J T P & Deegan, T D 2021, ' A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes ', Nature . https://doi.org/10.1038/s41586-021-04145-3

مصطلحات موضوعية: DNA Replication, Zinc finger, chemistry.chemical_classification, DNA ligase, Multidisciplinary, biology, Cryo-electron microscopy, Chemistry, Mechanism (biology), Ubiquitin-Protein Ligases, Cryoelectron Microscopy, DNA Helicases, Eukaryota, Eukaryotic DNA replication, DNA, Article, Cell biology, chemistry.chemical_compound, Ubiquitin, Electron microscopy, biology.protein, Humans, Replisome

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3762dde9c47e717fe2f32dd809798c47
https://doi.org/10.1038/s41586-021-04145-3

المؤلفون: Berta Canal, Tom D Deegan, Karim Labib, Agustina P Bertolin, Rupert Beale, John F.X. Diffley, Florian Weissmann, Michael Howell, Ryo Fujisawa, Mary Wu, Lucy S. Drury, Rachel Ulferts, Allison W McClure, Jingkun Zeng

المصدر: Biochemical Journal

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Endoribonuclease activity, Endoribonuclease, coronavirus, Drug Evaluation, Preclinical, Biology, In Vitro Techniques, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Antiviral Agents, endonuclease, Fluorescence, Chemical library, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, Biochemical Techniques & Resources, Allosteric Regulation, Exoribonuclease, Virology, Chlorocebus aethiops, Endoribonucleases, medicine, Animals, Molecular Biology, Vero Cells, Research Articles, Coronavirus, Enzyme Assays, SARS-CoV-2, COVID-19, Reproducibility of Results, Cell Biology, High-Throughput Screening Assays, Solutions, Kinetics, 030104 developmental biology, chemistry, nsp15, 030220 oncology & carcinogenesis, Vero cell, Antiviral drug, Viral genome replication, Naphthoquinones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3c0762d3a6f4930c63db5b106f20b7
http://europepmc.org/articles/PMC8286823

المؤلفون: Kang Wei Tan, Emma L. Roberts, Tiffany Mak, Lucy S. Drury, Souradeep Basu, Berta Canal, Michael Howell, Joseph F. Curran, Florian Weissmann, Karim Labib, Tom D Deegan, John F.X. Diffley, Allison W McClure, Ryo Fujisawa, Mary Wu, Victoria H. Cowling, Rachel Ulferts, Clovis Basier, Rupert Beale, Theresa U. Zeisner, Chew Theng Lim

المصدر: Biochemical Journal

مصطلحات موضوعية: Methyltransferase, Indoles, coronavirus, Drug Evaluation, Preclinical, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Substrate Specificity, Phenothiazines, Chlorocebus aethiops, Fluorescence Resonance Energy Transfer, Coronaviridae, Viral Regulatory and Accessory Proteins, Research Articles, Coronavirus, 0303 health sciences, Alanine, Translation (biology), Small molecule, covid-19, Indenes, mRNA cap, RNA Caps, Indazoles, Viral protein, Biology, Chlorobenzenes, Antiviral Agents, Small Molecule Libraries, 03 medical and health sciences, Biochemical Techniques & Resources, Trifluperidol, Virology, Nitriles, medicine, Animals, Molecular Biology, Vero Cells, 030304 developmental biology, Enzyme Assays, 030306 microbiology, SARS-CoV-2, RNA, Reproducibility of Results, Cell Biology, Methyltransferases, biology.organism_classification, Adenosine Monophosphate, High-Throughput Screening Assays, Viral replication, Purines, Exoribonucleases, methyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74acc162b19fe84f371a9c793c9d9297
http://europepmc.org/articles/PMC8286817

المؤلفون: Chew Theng Lim, Kang Wei Tan, Mary Wu, Rachel Ulferts, Lee A. Armstrong, Eiko Ozono, Lucy S. Drury, Jennifer C. Milligan, Theresa U. Zeisner, Jingkun Zeng, Florian Weissmann, Berta Canal, Ganka Bineva-Todd, Michael Howell, Nicola O'Reilly, Rupert Beale, Yogesh Kulathu, Karim Labib, John F.X. Diffley

المصدر: Biochemical Journal

مصطلحات موضوعية: 0301 basic medicine, viruses, coronavirus, Drug Evaluation, Preclinical, Coronavirus Papain-Like Proteases, Naphthalenes, Virus Replication, Biochemistry, Antiviral Agents, Small Molecule Libraries, 03 medical and health sciences, Inhibitory Concentration 50, 0302 clinical medicine, Biochemical Techniques & Resources, Virology, Flavins, ubiquitin, Chlorocebus aethiops, Fluorescence Resonance Energy Transfer, Animals, Furans, Molecular Biology, Vero Cells, Research Articles, Enzyme Assays, Alanine, Aniline Compounds, SARS-CoV-2, Quinones, COVID-19, Reproducibility of Results, protease, Drug Synergism, Cell Biology, Phenanthrenes, Adenosine Monophosphate, High-Throughput Screening Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Benzamides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc295ebc783870d82ca11f9dd713752
http://europepmc.org/articles/PMC8286840

المؤلفون: Michael R Botchan, Karim Labib

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd8923a96a3f3ccbac1becb4d4529da7
https://doi.org/10.7554/elife.77393.sa1

المؤلفون: Remi Sonneville, Tom D Deegan, Yisui Xia, Ryo Fujisawa, Karim Labib

المصدر: The EMBO Journal

مصطلحات موضوعية: DNA Replication, CMG helicase, CUL‐2LRR‐1, Synthetic lethality, DNA-Directed DNA Polymerase, General Biochemistry, Genetics and Molecular Biology, Article, Ubiquitin, Multienzyme Complexes, Animals, CDC‐48, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, UBXN‐3, General Immunology and Microbiology, biology, General Neuroscience, Helicase, Signal transducing adaptor protein, DNA Replication, Repair & Recombination, Post-translational Modifications, Proteolysis & Proteomics, Articles, biology.organism_classification, Cullin Proteins, TIMELESS‐TIPIN, Ubiquitin ligase, Cell biology, DNA replication termination, biology.protein, Replisome, Carrier Proteins, Synthetic Lethal Mutations

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9119b29ea961c229495c12108e47927
https://pubmed.ncbi.nlm.nih.gov/34269473

المؤلفون: Johanna Ainsworth, Thanh Thi Le, Thomas Macartney, Karim Labib, Cristian Polo Rivera

المصدر: Biochemical Journal

مصطلحات موضوعية: p97, CMG helicase, Protein subunit, Ubiquitin-Protein Ligases, Immunoblotting, cullin ligase, Spodoptera, Biochemistry, Cell Line, DNA synthesis and repair, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, ubiquitins, Valosin Containing Protein, Sf9 Cells, Animals, Humans, Cloning, Molecular, Molecular Biology, DNA, Chromosomes & Chromosomal Structure, Research Articles, 030304 developmental biology, chemistry.chemical_classification, CUL2LRR1, 0303 health sciences, Post-Translational Modifications, biology, Chemistry, Lysine, DNA Helicases, Ubiquitination, Helicase, Cell Biology, Cullin Proteins, Minichromosome Maintenance Complex Component 7, Cell biology, Repressor Proteins, Ubiquitins, Enzyme, Ubiquitin-Conjugating Enzymes, Cell Cycle, Growth & Proliferation, biology.protein, DNA replication termination, Replisome, 030217 neurology & neurosurgery, Cullin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f068f8dbb5cdef2c224c6af22c79442
https://pubmed.ncbi.nlm.nih.gov/34195792

المؤلفون: Rachel Ulferts, Souradeep Basu, John F.X. Diffley, Tom D Deegan, Joseph F. Curran, Lucy S. Drury, Chew Theng Lim, Tiffany Mak, Ryo Fujisawa, Clovis Basier, Mary Wu, Karim Labib, Theresa U. Zeisner, Kang Wei Tan, Florian Weissmann, Victoria H. Cowling, Michael Howell, Rupert Beale, Allison W McClure, Emma A. Roberts, Berta Canal

مصطلحات موضوعية: chemistry.chemical_classification, Methyltransferase, biology, Viral protein, RNA, Translation (biology), biology.organism_classification, medicine.disease_cause, Virology, Small molecule, Enzyme, Viral replication, chemistry, medicine, Coronaviridae

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f9af0849d5ef9495919122a84bdc9c1
https://doi.org/10.1101/2021.04.07.438810

المؤلفون: Mary Wu, Clovis Basier, George Papageorgiou, Michael Howell, Christelle Soudy, Theresa U. Zeisner, Rachel Ulferts, John F.X. Diffley, Chew Theng Lim, Dhira Joshi, Joseph F. Curran, Florian Weissmann, Hema Nagaraj, Tom D Deegan, Ryo Fujisawa, Berta Canal, Karim Labib, Kang Wei Tan, Ganka Bineva-Todd, Jennifer C. Milligan, Rupert Beale

مصطلحات موضوعية: Protease, Peptidomimetic, viruses, medicine.medical_treatment, medicine.disease_cause, Virology, In vitro, Chemical library, chemistry.chemical_compound, Papain, chemistry, Viral replication, medicine, Vero cell, Coronavirus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e9335764f2cf6ed64e157d65e251c782
https://doi.org/10.1101/2021.04.07.438804

المؤلفون: Florian Weissmann, Chew Theng Lim, Clovis Basier, Christelle Soudy, Nicola O’Reilly, Karim Labib, Tom D Deegan, Ganka Bineva-Todd, Theresa U. Zeisner, Kang Wei Tan, Berta Canal, Rachel Ulferts, John F.X. Diffley, Dhira Joshi, Rupert Beale, Jennifer C. Milligan, Joseph F. Curran, George Papageorgiou, Michael Howell, Mary Wu, Ryo Fujisawa, Hema Nagaraj

المصدر: Biochemical Journal

مصطلحات موضوعية: Azoles, Leupeptins, Peptidomimetic, viruses, medicine.medical_treatment, Drug Evaluation, Preclinical, coronavirus, Isoindoles, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Amino Acid Chloromethyl Ketones, Chemical library, chemistry.chemical_compound, 0302 clinical medicine, Organoselenium Compounds, Chlorocebus aethiops, nsp5, Fluorescence Resonance Energy Transfer, Coronavirus 3C Proteases, Research Articles, Coronavirus, 0303 health sciences, RNA-Binding Proteins, Antiviral Agents, Small Molecule Libraries, 03 medical and health sciences, Biochemical Techniques & Resources, Virology, medicine, Animals, Vero Cells, Molecular Biology, Enzyme Assays, 030304 developmental biology, Protease, SARS-CoV-2, Leupeptin, Reproducibility of Results, COVID-19, protease, Cell Biology, In vitro, High-Throughput Screening Assays, Viral replication, chemistry, Vero cell, Peptidomimetics, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d3622d6627d0c0a5a33acb1408e403
https://doi.org/10.1101/2021.04.07.438806