المؤلفون: Brian A Droz, Bria L Sneed, Charles V Jackson, Karen M Zimmerman, M Dodson Michael, Paul J Emmerson, Tamer Coskun, Richard G Peterson

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179808 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/bb9f14c1cae741f99f99a57996878039

المؤلفون: Richard G Peterson, Charles Van Jackson, Karen M Zimmerman, Jorge Alsina-Fernandez, M Dodson Michael, Paul J Emmerson, Tamer Coskun

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179856 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5480999?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fdbd942c01ab4fed9cac047452dc65e7

المؤلفون: Guoqing Cao, Thomas P. Beyer, Youyan Zhang, Robert J. Schmidt, Yan Q. Chen, Sandra L. Cockerham, Karen M. Zimmerman, Sotirios K. Karathanasis, Ellen A. Cannady, Todd Fields, Nathan B. Mantlo

المصدر: Journal of Lipid Research, Vol 52, Iss 12, Pp 2169-2176 (2011)

مصطلحات موضوعية: CETP, cholesterol, cholesterol/metabolism, drug therapy, lipoproteins/metabolism, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520408211; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/814d7db5161b4c7e8b11650ddcf3aa93

المؤلفون: Courtney Finnearty, Charles V. Jackson, Yixin Wang, Karen M. Zimmerman, Richard G. Peterson, Guodong Zhang, George E. Sandusky, Li-Kun Zhang, Gao Sun

المصدر: BMC Gastroenterology
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Male, medicine.medical_specialty, Metabolic disease, Fructose, Type 2 diabetes, Diet, High-Fat, digestive system, High cholesterol, Mice, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Insulin resistance, Non-alcoholic Fatty Liver Disease, FATZO mouse, NAFLD, Internal medicine, Animals, Medicine, Obesity, lcsh:RC799-869, business.industry, Fatty liver, NASH, Gastroenterology, nutritional and metabolic diseases, General Medicine, medicine.disease, digestive system diseases, Disease Models, Animal, Endocrinology, Diabetes Mellitus, Type 2, Liver, Diet, Western, Sweetening Agents, 030220 oncology & carcinogenesis, Disease Progression, lcsh:Diseases of the digestive system. Gastroenterology, 030211 gastroenterology & hepatology, Liver function, Steatosis, Steatohepatitis, business, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d5e5aec897049aae466b28bb6f2a5a
https://doi.org/10.1186/s12876-019-0958-4

المؤلفون: Richard G. Peterson, Karen M. Zimmerman, M. Dodson Michael, Bria L. Sneed, Paul J. Emmerson, Brian A. Droz, Charles V. Jackson, Tamer Coskun

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179808 (2017)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Leptin, Blood Glucose, Male, Physiology, medicine.medical_treatment, Peptide Hormones, Type 2 diabetes, Biochemistry, Fats, Eating, Mice, 0302 clinical medicine, Endocrinology, Hyperinsulinemia, Medicine and Health Sciences, Medicine, Insulin, 2. Zero hunger, Multidisciplinary, Organic Compounds, Monosaccharides, Animal Models, Lipids, 3. Good health, Chemistry, Physiological Parameters, Experimental Organism Systems, Physical Sciences, medicine.symptom, Research Article, medicine.medical_specialty, Offspring, Science, Carbohydrates, 030209 endocrinology & metabolism, Mouse Models, Research and Analysis Methods, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Model Organisms, Diabetes mellitus, Internal medicine, Animals, Obesity, Pancreas, Nutrition, Diabetic Endocrinology, business.industry, Body Weight, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, medicine.disease, Hormones, Diet, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, business, Weight gain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff96d25ea08c7654451bfe234ee4c5a
https://doaj.org/article/bb9f14c1cae741f99f99a57996878039

المؤلفون: David Andrew Neel, Karen M. Zimmerman, Matthew L. Brown, Prabhakar Kondaji Jadhav, Robert Anthony Doti, Defauw Jean Marie, Stephon C. Smith, Peter Ambrose Lander, Sally Ann Kelley, Todd Fields, Timothy Alan Grese, Mitchell I. Steinberg

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:2553-2557

مصطلحات موضوعية: Indoles, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Steroid, Radioligand Assay, chemistry.chemical_compound, Mineralocorticoid receptor, Drug Discovery, medicine, Humans, skin and connective tissue diseases, Molecular Biology, Mineralocorticoid Receptor Antagonists, Chemistry, fungi, Organic Chemistry, Antagonist, In vitro, body regions, Nuclear receptor, Lactam, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1d4dba037b66ab19558a85f754cd62
https://doi.org/10.1016/j.bmcl.2005.03.086

المؤلفون: Michael K. Hansen, Norman D. Huebert, Charles V. Jackson, Karen M. Zimmerman, Richard G. Peterson, Willem de Winter

المصدر: Journal of Diabetes Research
Journal of Diabetes Research, Vol 2015 (2015)

مصطلحات موضوعية: Blood Glucose, Leptin, Male, medicine.medical_specialty, Article Subject, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Population, Type 2 diabetes, lcsh:Diseases of the endocrine glands. Clinical endocrinology, Endocrinology, Insulin resistance, Diabetes mellitus, Internal medicine, Glucose Intolerance, medicine, Animals, Insulin, Obesity, education, Metabolic Syndrome, education.field_of_study, lcsh:RC648-665, business.industry, nutritional and metabolic diseases, medicine.disease, Rats, Disease Models, Animal, Diabetes Mellitus, Type 2, Metabolic syndrome, Insulin Resistance, business, Dyslipidemia, Signal Transduction, Research Article

وصف الملف: text/xhtml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9a11f31919db9f7ece9693f8b4ecf1
https://pubmed.ncbi.nlm.nih.gov/25961053

المؤلفون: Matthew D. Belvo, Michael Gregory Bell, Douglas Linn Gernert, V. Scott Sharp, Joseph H. Kennedy, Hannah Yu, Peter Stanley Borromeo, Timothy Alan Grese, Sally Ann Kelley, Gregory A. Stephenson, Mitchell I. Steinberg, Prabhakar Kondaji Jadhav, Jeffrey D. Williams, Karen M. Zimmerman, Rachel N. Richey, Stanley P. Kolis, Peter Ambrose Lander

المصدر: Journal of Medicinal Chemistry. 50:6443-6445

مصطلحات موضوعية: Models, Molecular, Indole test, Sulfonamides, Indoles, Stereochemistry, Chemistry, Antagonist, Stereoisomerism, Biological activity, Crystallography, X-Ray, Chemical synthesis, Rats, Rats, Sprague-Dawley, Structure-Activity Relationship, Mineralocorticoid receptor, In vivo, Drug Discovery, Animals, Molecular Medicine, Structure–activity relationship, Antihypertensive Agents, Mineralocorticoid Receptor Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7278bc07b6e6e72013351da2997c964
https://doi.org/10.1021/jm701186z

المؤلفون: Alan David Palkowitz, Donald B. Boyd, Kenneth Lee Hauser, Mitchell I. Steinberg, Karen M. Zimmerman, K. Jeff Thrasher

المصدر: Bioorganic & Medicinal Chemistry Letters. 5:1015-1020

مصطلحات موضوعية: Benzimidazole, Angiotensin receptor, Aryl, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Angiotensin II, chemistry.chemical_compound, chemistry, Drug Discovery, Molecular Medicine, Imidazole, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a8d0a626b825c642d1f71a428dada9e8
https://doi.org/10.1016/0960-894x(95)00159-q

المؤلفون: Mitchell I. Steinberg, Kenneth Jeff Thrasher, Pfeifer William, Celia Ann Whitesitt, Kenneth Lee Hauser, Alan David Carmel Palkowitz, Karen M. Zimmerman, Sally A. Wiest, Jon K. Reel, Richard Lee Simon

المصدر: Journal of Medicinal Chemistry. 37:4508-4521

مصطلحات موضوعية: Male, Angiotensin receptor, medicine.drug_class, Stereochemistry, Carboxamide, Pharmacology, Chemical synthesis, Rats, Sprague-Dawley, Angiotensin Receptor Antagonists, Structure-Activity Relationship, Spontaneously hypertensive rat, In vivo, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Receptor, Antihypertensive Agents, Chemistry, Angiotensin II, Rats, Losartan, Molecular Medicine, Rabbits, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f4cfd5eafcb562336485c291efa4b7
https://doi.org/10.1021/jm00052a010

المؤلفون: Donald B. Boyd, K. Takeuchi, Pfeifer William, Richard Lee Simon, Kenneth Jeff Thrasher, K.G. Bermis, Winston Stanley Marshall, Karen M. Zimmerman, Alan David Carmel Palkowitz, Jon K. Reel, Lifer Sherryl Lynn, Celia Ann Whitesitt, Sally A. Wiest, Thomas Michael Wilson, Venkatraghavan Vasudevan, Kenneth Lee Hauser, Jack B. Deeter, Mitchell I. Steinberg, Charles Jackson Barnett

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:51-56

مصطلحات موضوعية: Angiotensin II receptor type 1, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Diastereomer, Pharmaceutical Science, Biological activity, Biochemistry, Chemical synthesis, Angiotensin II, In vitro, Drug Discovery, Molecular Medicine, Receptor, Molecular Biology, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e3bf8f385807f9691ffe04c6eccbf4e
https://doi.org/10.1016/s0960-894x(01)81121-5

المؤلفون: Nathan Bryan Mantlo, Youyan Zhang, Sandra L. Cockerham, Sotirios K. Karathanasis, Karen M. Zimmerman, Thomas P. Beyer, Guoqing Cao, Ellen A. Cannady, Robert J. Schmidt, Yan Q. Chen, Todd Fields

المصدر: Journal of Lipid Research, Vol 52, Iss 12, Pp 2169-2176 (2011)

مصطلحات موضوعية: Male, medicine.medical_specialty, cholesterol/metabolism, Blood Pressure, QD415-436, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Benzodiazepines, Mice, Endocrinology, lipoproteins/metabolism, Mice, Inbred NOD, Internal medicine, Cell Line, Tumor, Cholesterylester transfer protein, CETP, medicine, Animals, Humans, CETP inhibitor, Aldosterone, Research Articles, biology, Cholesterol, Cholesterol, HDL, Torcetrapib, cholesterol, Cell Biology, drug therapy, Cholesterol Ester Transfer Proteins, Rats, carbohydrates (lipids), chemistry, Cholesteryl ester, biology.protein, lipids (amino acids, peptides, and proteins), Evacetrapib, Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2b0fc5f8e6c4687b31c3ca39062428
https://pubmed.ncbi.nlm.nih.gov/21957197

المؤلفون: Robert Theodore Vasileff, Brown Raymond Frank, J. F. Quay, F. T. Counter, J. A. Webber, E. O. Davidson, Terry D. Lindstrom, Jeffrey S. Kasher, William Henry Walker Lunn, Mitchell I. Steinberg, J. M. Jun. Morin, J. A. Eudaly, Paul W. Ensminger, R. E. Koehler, Allen S. Katner, Michael Dean Kinnick, John K. Swartzendruber, Jan R. Turner, David A. Preston, J. K. Shadle, Walter E. Wright, J. F. Stucky, K. D. Kurz, John L. Ott, Karen M. Zimmerman

المصدر: ChemInform. 22

مصطلحات موضوعية: chemistry.chemical_compound, medicine.drug_class, Chemistry, Stereochemistry, Cephalosporin, medicine, Organic chemistry, Ammonium, General Medicine, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::386baf125ef02cf683bca51f026f46c4
https://doi.org/10.1002/chin.199104334

المؤلفون: Donald B. Boyd, Ho Shen Lin, Ashraff A. Rampersaud, Karen M. Zimmerman, Mitchell I. Steinberg

المصدر: Journal of Medicinal Chemistry. 35:2658-2667

مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, Tetrazoles, In Vitro Techniques, Ring (chemistry), Losartan, Angiotensin Receptor Antagonists, chemistry.chemical_compound, Computational chemistry, Drug Discovery, medicine, Animals, Imidazole, Moiety, Computer Simulation, Hydroxymethyl, Receptor, Biphenyl Compounds, Imidazoles, Rats, Inbred Strains, Rats, Biphenyl compound, chemistry, Molecular Medicine, Rabbits, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8776dd537fc142e0b2eeb9ca447fec70
https://doi.org/10.1021/jm00092a017

المؤلفون: Paul D. Gesellchen, Sally A. Wiest, Karen M. Zimmerman, Mitchell I. Steinberg

المصدر: Biochemical and Biophysical Research Communications. 170:462-469

مصطلحات موضوعية: Male, medicine.medical_specialty, genetic structures, Molecular Sequence Data, Angiotensinogen, Biophysics, Aorta, Thoracic, Peptide hormone, Biology, Binding, Competitive, Biochemistry, Non-competitive inhibition, Cell surface receptor, Internal medicine, medicine, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Receptor, Molecular Biology, Gene, chemistry.chemical_classification, Messenger RNA, Receptors, Angiotensin, Base Sequence, Angiotensin II, Cell Membrane, Rats, Inbred Strains, Cell Biology, Adrenergic beta-Agonists, Rats, Amino acid, Endocrinology, chemistry, cardiovascular system, Zona Glomerulosa, Rabbits, sense organs, hormones, hormone substitutes, and hormone antagonists, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14308ef0cfe1981c08bffaa2059cfb84
https://doi.org/10.1016/0006-291x(90)92114-f

المؤلفون: Stuart Friedrich, Evelyn D. Lobo, Karen M. Zimmerman, Carlos Garner, Anthony G. Borel

المصدر: Biotechnology: Pharmaceutical Aspects ISBN: 9780387340562

مصطلحات موضوعية: Pharmaceutical drug, Finance, business.industry, medicine.medical_treatment, Drug prices, Discount points, Food and drug administration, Lead (geology), White paper, medicine, business, health care economics and organizations, PK/PD models, Pharmaceutical industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93cd621d652be34345083d783cc479a9
https://doi.org/10.1007/978-0-387-44961-6_15

المؤلفون: Boris A. Czeskis, Minxia M. He, Mitchell I. Steinberg, Wolfgang Stenzel, Wirth David Dale, Karen M. Zimmerman, Ulrike Roettig

المصدر: European journal of medicinal chemistry. 37(1)

مصطلحات موضوعية: medicine.medical_specialty, Time Factors, Pyrimidine, Metabolite, Administration, Oral, Blood Pressure, Mice, Inbred Strains, Pharmacology, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Pharmacokinetics, Imidazolidine, Oral administration, Heart Rate, Internal medicine, Drug Discovery, medicine, Animals, Humans, Antihypertensive Agents, Moxonidine, Organic Chemistry, Imidazoles, Biological activity, General Medicine, Metabolism, Rats, Inbred F344, Rats, Endocrinology, chemistry, Oxidation-Reduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5045b98a912def29eac4e08fbe6218a2
https://pubmed.ncbi.nlm.nih.gov/11841872

المؤلفون: Mitchell I Steinberg, Sally A Wiest, Karen M Zimmerman, Phillip J Ertel, Kerry G Bemis, David W Robertson

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jpet.aspetjournals.org/content/jpet/256/1/222.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.8249; http://jpet.aspetjournals.org/content/jpet/256/1/222.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.8249
http://jpet.aspetjournals.org/content/jpet/256/1/222.full.pdf

المؤلفون: Original Investigation, Xiao Lu, Xiaomei Guo, Sotirios K Karathanasis, Karen M Zimmerman, Jude E Onyia, Richard G Peterson, Ghassan S Kassab

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.biomedcentral.com/content/pdf/1475-2840-9-19.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.5935; http://www.biomedcentral.com/content/pdf/1475-2840-9-19.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.5935
http://www.biomedcentral.com/content/pdf/1475-2840-9-19.pdf

المؤلفون: Donald B. Boyd, Pfeifer William, Kumiko Takeuchi, Celia Ann Whitesitt, Jon K. Reel, Vasu Vasudevan, Alan David Palkowitz, Richard Lee Simon, Sally A. Wiest, Kenneth Lee Hauser, Aaron D. Kossoy, Jack B. Deeter, Lifer Sherryl Lynn, K. Jeff Thrasher, Winston Stanley Marshall, Karen M. Zimmerman, Mitchell I. Steinberg

المصدر: ACS Symposium Series ISBN: 9780841231603
Computer-Aided Molecular Design: Applications in Agrochemicals, Materials, and Pharmaceuticals

مصطلحات موضوعية: Angiotensin receptor, Quantitative structure–activity relationship, Molecular model, Biochemistry, Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d864bf657ccd6412e142eb39a941696c
https://doi.org/10.1021/bk-1995-0589.ch002