المؤلفون: Mariany L. C. Folly, Gabriella F. Ferreira, Maiara R. Salvador, Ana A. Sathler, Guilherme F. da Silva, Joice Castelo Branco Santos, Julliana R. A. dos Santos, Wallace Ribeiro Nunes Neto, João Francisco Silva Rodrigues, Elizabeth Soares Fernandes, Luís Cláudio Nascimento da Silva, Gustavo José Cota de Freitas, Ângelo M. Denadai, Ivanildes V. Rodrigues, Leonardo M. Mendonça, Andrea Souza Monteiro, Daniel Assis Santos, Gabriela M. Cabrera, Gastón Siless, Karen L. Lang

المصدر: Frontiers in Microbiology, Vol 10 (2020)

مصطلحات موضوعية: Cryptococcus spp., Xylosma prockia, antifungal agents, natural products, biodiversity, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.03114/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/c18e9606fb724a53a9676d9ef8aabc55

المؤلفون: Vanessa R. Machado, Karen L. Lang, Fernando J. Durán, Gabriela M. Cabrera, Jorge A. Palermo, Eloir P. Schenkel, Lílian S. C. Bernardes

المصدر: Química Nova, Vol 38, Iss 1, Pp 37-41 (2015)

مصطلحات موضوعية: Wilbrandia ebracteata, glycosylated cucurbitacins, O-glycosylation reaction, molecular modification, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000100037&lng=en&tlng=en; https://doaj.org/toc/1678-7064

URL الوصول: https://doaj.org/article/b33f083b05af4dd0965afae5f9686f60

المؤلفون: Eloir P. Schenkel, Fernando J. Durán, Cláudia M. O. Simões, Miriam Falkenberg, Jorge A. Palermo, Maria V. Mañalich Arana, Cíntia Lhullier, Izabella T. Silva, Lara A. Zimmermann, Karen L. Lang

المصدر: Marine Drugs, Vol 10, Iss 10, Pp 2254-2264 (2012)

مصطلحات موضوعية: elatol, isoobtusol, sesquiterpenes, synthesis, cytotoxic activity, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1660-3397/10/10/2254; https://doaj.org/toc/1660-3397

URL الوصول: https://doaj.org/article/9eabc32edbb44e15b7a9794d8d2b5c45

المؤلفون: Karen L. Lang, Gabriella Freitas Ferreira, Emanuel Almeida Moreira de Oliveira

المصدر: Medicinal Chemistry Research. 31:26-39

مصطلحات موضوعية: Drug, medicine.medical_specialty, biology, Chemistry, media_common.quotation_subject, Organic Chemistry, Mebendazole, Cryptococcus, Flubendazole, Disease, biology.organism_classification, medicine.disease, Drug repositioning, chemistry.chemical_compound, Cryptococcosis, medicine, Anthelmintic, General Pharmacology, Toxicology and Pharmaceutics, Intensive care medicine, medicine.drug, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4554be4d4f6976643c8c17e190ef15e
https://doi.org/10.1007/s00044-021-02824-4

المؤلفون: Carla da Silva Machado, Maiara R. Salvador, Daniel M. Machado, Leonardo Meneghin Mendonça, Karen L. Lang

المصدر: Brazilian Journal of Health and Pharmacy. 3:12-21

مصطلحات موضوعية: Alismataceae, biology, Traditional medicine, Echinodorus macrophyllus, biology.organism_classification, medicine.disease_cause, Peripheral blood mononuclear cell, In vitro, medicine, General Earth and Planetary Sciences, Cytotoxic T cell, Cytotoxicity, Micronucleus, Genotoxicity, General Environmental Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::00fc57300ed5907a904f0ad860877ca0
https://doi.org/10.29327/226760.3.1-2

المؤلفون: Izabella T Silva, Annelise Carvalho, Karen L Lang, Sabine E Dudek, Dörthe Masemann, Fernando J Durán, Miguel S B Caro, Ulf R Rapp, Viktor Wixler, Eloir P Schenkel, Cláudia M O Simões, Stephan Ludwig

المصدر: PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC4326133?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/229051bf1cf8454caca58ab6e36010c1

الاتاحة: https://doi.org/10.1371/journal.pone.0117794
https://doaj.org/article/229051bf1cf8454caca58ab6e36010c1

المؤلفون: Maiara R. Salvador, Karen L. Lang, Carla da Silva Machado, Paulo César Stringheta, Daniel M. Machado, Michele Correa Bertoldi, Iann Lucas Lago e S. Mascarenhas, Leonardo M. Machado

المصدر: Corantes Naturais: da diversidade da natureza as aplicações e benefícios

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4326909cdbab2f924fb58b5ff94471b6
https://doi.org/10.29327/540979.1-8

المؤلفون: Isoobtusol, Karen L. Lang, Izabella T. Silva, Lara A. Zimmermann, Cíntia Lhullier, Maria V. Mañalich Arana, Jorge A. Palermo, Miriam Falkenberg, Cláudia M. O. Simões, Eloir P. Schenkel, O J. Durán

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1660-3397/10/10/2254/pdf/.

مصطلحات موضوعية: elatol, isoobtusol, sesquiterpenes, synthesis, cytotoxic activityMar. Drugs 2012, 10 2255

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.393.8170; http://www.mdpi.com/1660-3397/10/10/2254/pdf/

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.393.8170
http://www.mdpi.com/1660-3397/10/10/2254/pdf/

المؤلفون: Mariany L C, Folly, Gabriella F, Ferreira, Maiara R, Salvador, Ana A, Sathler, Guilherme F, da Silva, Joice Castelo Branco, Santos, Julliana R A, Dos Santos, Wallace Ribeiro, Nunes Neto, João Francisco Silva, Rodrigues, Elizabeth Soares, Fernandes, Luís Cláudio Nascimento, da Silva, Gustavo José Cota, de Freitas, Ângelo M, Denadai, Ivanildes V, Rodrigues, Leonardo M, Mendonça, Andrea Souza, Monteiro, Daniel Assis, Santos, Gabriela M, Cabrera, Gastón, Siless, Karen L, Lang

المصدر: Frontiers in Microbiology

مصطلحات موضوعية: natural products, Cryptococcus spp, Xylosma prockia, antifungal agents, Microbiology, Original Research, biodiversity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::78ef5b0cbf5e386c7e10b84b92dd6529
https://pubmed.ncbi.nlm.nih.gov/32117083

المؤلفون: Mariany L. C. Folly, Gabriella F. Ferreira, Maiara R. Salvador, Ana A. Sathler, Guilherme F. da Silva, Joice Castelo Branco Santos, Julliana R. A. dos Santos, Wallace Ribeiro Nunes Neto, João Francisco Silva Rodrigues, Elizabeth Soares Fernandes, Luís Cláudio Nascimento da Silva, Gustavo José Cota de Freitas, Ângelo M. Denadai, Ivanildes V. Rodrigues, Leonardo M. Mendonça, Andrea Souza Monteiro, Daniel Assis Santos, Gabriela M. Cabrera, Gastón Siless, Karen L. Lang

مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, Cryptococcus spp, Xylosma prockia, antifungal agents, natural products, biodiversity

Relation: https://figshare.com/articles/dataset/Data_Shee_1_Evaluation_of_in_vitro_Antifungal_Activity_of_Xylosma_prockia_Turcz_Turcz_Salicaceae_Leaves_Against_Cryptococcus_spp_docx/11813604

الاتاحة: https://doi.org/10.3389/fmicb.2019.03114.s001
https://figshare.com/articles/dataset/Data_Shee_1_Evaluation_of_in_vitro_Antifungal_Activity_of_Xylosma_prockia_Turcz_Turcz_Salicaceae_Leaves_Against_Cryptococcus_spp_docx/11813604

المؤلفون: Eloir Paulo Schenkel, Ana Luísa Malaco Morotti, Ivone Carvalho, Karen L. Lang, Lílian Sibelle Campos Bernardes

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Stereochemistry, Cucurbitacin, Organic Chemistry, Triazole, Glycoside, BIOLOGIA CELULAR, Glycosidic bond, Cucurbitane, Galactoside, Biochemistry, chemistry.chemical_compound, Cucurbitacins, Drug Discovery, Moiety, Organic chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3bdba159fff8f5850370a4467a89b0

المؤلفون: Sabine Eva Dudek, Cláudia Maria Oliveira Simões, Marina Rodrigues Teixeira, Izabella Thaís Silva, Eloir Paulo Schenkel, Miguel S. B. Caro, Tatiana da Rosa Guimarães, Karen L. Lang, Stephan Ludwig, Fernando Javier Duran

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: A549 cell, Cancer Research, Mechanism (biology), Cucurbitacin, Chemistry, CUCURBITACINS, LUNG CANCER, Bioquímica y Biología Molecular, Wilbrandia ebracteata, medicine.disease, Ciencias Biológicas, purl.org/becyt/ford/1 [https], Cucurbitacins, Oncology, Apoptosis, Cancer research, medicine, Non small cell, A549 CELL, purl.org/becyt/ford/1.6 [https], Lung cancer, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8f9fea9e9bc6c2c39dab2d36302d5f
https://doi.org/10.3923/ijcr.2013.54.68

المؤلفون: Jorge Alejandro Palermo, Eloir Paulo Schenkel, Lara Almida Zimmermann, Carmen Rossini, Karen L. Lang, Vanessa Rocha Machado, Lílian Sibelle Campos Bernardes, Fernando Javier Duran, Emilio Deagosto

المصدر: Journal of Agricultural and Food Chemistry. 61:5534-5539

مصطلحات موضوعية: media_common.quotation_subject, SEMISINTESIS, Allomone, Insect, Lepidoptera genitalia, Cucurbitacins, Species Specificity, Botany, Animals, ANTIINSECTO, media_common, Molecular Structure, biology, Plant Extracts, DETERRENTE, Cucurbitacin, Otras Ciencias Químicas, Ciencias Químicas, Feeding Behavior, General Chemistry, biology.organism_classification, ANTIHERVIVORO, Coleoptera, Lepidoptera, Cucurbitaceae, TRITERPENOIDE, Kairomone, CUCURBITACINAS, Noctuidae, Coccinellidae, General Agricultural and Biological Sciences, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59154cb3faedf87ed6ce334ac32a4ae4
https://doi.org/10.1021/jf4002457

المؤلفون: Jorge Alejandro Palermo, Eloir Paulo Schenkel, Miriam Falkenberg, Karen L. Lang

المصدر: Biochemical Systematics and Ecology. 35:805-808

مصطلحات موضوعية: ACANTHOPHORA SPICIFERA, Acanthophora spicifera, biology, Stereochemistry, STEROIDS, Otras Ciencias Químicas, Ciencias Químicas, CHOLEST-4-EN-3,6-DIONE, biology.organism_classification, Biochemistry, 6Β-HYDROXY-CHOLEST-4-EN-3-ONE, CIENCIAS NATURALES Y EXACTAS, Ecology, Evolution, Behavior and Systematics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbf795db64e8366b6621df5d06bd96c
https://doi.org/10.1016/j.bse.2007.04.001

المؤلفون: Izabella T, Silva, Annelise, Carvalho, Karen L, Lang, Sabine E, Dudek, Dörthe, Masemann, Fernando J, Durán, Miguel S B, Caro, Ulf R, Rapp, Viktor, Wixler, Eloir P, Schenkel, Cláudia M O, Simões, Stephan, Ludwig

المصدر: PLoS ONE

مصطلحات موضوعية: Male, STAT3 Transcription Factor, Lung Neoplasms, Antineoplastic Agents, Apoptosis, Mice, Transgenic, Mice, Phosphatidylinositol 3-Kinases, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Animals, Humans, Phosphorylation, Cytoskeleton, Tumor Stem Cell Assay, Cell Proliferation, Caspase 3, Cell Cycle Checkpoints, Xenograft Model Antitumor Assays, Triterpenes, respiratory tract diseases, ErbB Receptors, Disease Models, Animal, raf Kinases, Apoptosis Regulatory Proteins, Proto-Oncogene Proteins c-akt, Signal Transduction, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::703f9e9cec14dc0cdecfb10875cf644a
https://pubmed.ncbi.nlm.nih.gov/25674792

المؤلفون: Eloir Paulo Schenkel, Izabella Thaís Silva, Lara Almida Zimmermann, Fernando Javier Duran, Miguel S. B. Caro, Eduardo Borges de Melo, Vanessa Rocha Machado, Cláudia Maria Oliveira Simões, Karen L. Lang, Lílian Sibelle Campos Bernardes

المصدر: Journal of molecular graphicsmodelling. 48

مصطلحات موضوعية: Multivariate statistics, Quantitative structure–activity relationship, Stereochemistry, Quantitative Structure-Activity Relationship, CUCURBITACINS, Antineoplastic Agents, PLS, Human lung, Inhibitory Concentration 50, Cucurbitacins, Cell Line, Tumor, Partial least squares regression, Materials Chemistry, medicine, Cytotoxic T cell, Humans, Physical and Theoretical Chemistry, Cytotoxicity, Spectroscopy, Cucurbitacin, Chemistry, QSAR, Otras Ciencias Químicas, Ciencias Químicas, LUNG CANCER, Computer Graphics and Computer-Aided Design, medicine.anatomical_structure, Biochemistry, Models, Chemical, Multivariate Analysis, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db81002eed68a443ca8f65e5c4f79cb
https://pubmed.ncbi.nlm.nih.gov/24378396

المؤلفون: Lara Almida Zimmermann, María Victoria Mañalich Arana, Cláudia Maria Oliveira Simões, Fernando Javier Duran, Jorge Alejandro Palermo, Izabella Thaís Silva, Karen L. Lang, Miriam Falkenberg, Eloir Paulo Schenkel, Cintia Lhullier

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Marine Drugs
Marine Drugs, Vol 10, Iss 10, Pp 2254-2264 (2012)
Marine Drugs; Volume 10; Issue 10; Pages: 2254-2264

مصطلحات موضوعية: Isoobtusol, Carbamate, isoobtusol, synthesis, Stereochemistry, medicine.medical_treatment, In vitro cytotoxicity, Pharmaceutical Science, Tumor cells, Antineoplastic Agents, SYNTHESIS, Laurencia, CYTOTOXIC ACTIVITY, Article, Semi synthetic, Cell Line, elatol, purl.org/becyt/ford/1 [https], sesquiterpenes, cytotoxic activity, Drug Discovery, medicine, purl.org/becyt/ford/1.4 [https], Molecule, Cytotoxic T cell, Humans, Spiro Compounds, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), lcsh:QH301-705.5, SESQUITERPENES, Molecular Structure, ELATOL, Chemistry, Otras Ciencias Químicas, Ciencias Químicas, Combinatorial chemistry, ISOOBTUSOL, In vitro, lcsh:Biology (General), CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4734340f0d6d838ec0cd18934cf967ec
https://www.mdpi.com/1660-3397/10/10/2254

المؤلفون: Tatiana da Rosa Guimarães, Jorge Alejandro Palermo, Eloir Paulo Schenkel, Cláudia Maria Oliveira Simões, Vanessa Rocha Machado, Marina Rodrigues Teixeira, Miguel S. B. Caro, Fernando Javier Duran, Lara Almida Zimmermann, Karen L. Lang, Izabella Thaís Silva

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Stereochemistry, Cell Survival, Pharmaceutical Science, CUCURBITACINS, Pharmacognosy, Biology, Plant Roots, Analytical Chemistry, WILBRANDIA EBRACTEATA, Cucurbitacins, CUCURBITACEAE, Triterpene, Cell Line, Tumor, Drug Discovery, Cytotoxic T cell, Humans, CYTOTOXICITY, Cytotoxicity, Chromatography, High Pressure Liquid, Pharmacology, chemistry.chemical_classification, Plants, Medicinal, Molecular Structure, Plant Extracts, Organic Chemistry, Ciencias Químicas, Wilbrandia ebracteata, Terpenoid, Cucurbitaceae, Química Orgánica, Complementary and alternative medicine, chemistry, Molecular Medicine, Medicine, Traditional, Brazil, CIENCIAS NATURALES Y EXACTAS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c05c4d0644cddf73ac169d0a3cf6be
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1270962

المؤلفون: Fábio S. Murakami, Cassiana Mendes, Karen L. Lang, Marco Aurélio da Silva Carvalho Filho, Ariane P. Cruz, Marcos Antonio Segatto Silva

المصدر: Journal of pharmaceutical and biomedical analysis. 49(1)

مصطلحات موضوعية: Hot Temperature, Diffuse reflectance infrared fourier transform, Chemical Phenomena, Clinical Biochemistry, Analytical chemistry, Pharmaceutical Science, Omeprazole Sodium, Analytical Chemistry, law.invention, Crystallinity, Differential scanning calorimetry, Drug Stability, X-Ray Diffraction, law, Drug Discovery, Spectroscopy, Fourier Transform Infrared, Crystallization, Enzyme Inhibitors, Thermal analysis, Nuclear Magnetic Resonance, Biomolecular, Spectroscopy, Calorimetry, Differential Scanning, Molecular Structure, Chemistry, Spectrum Analysis, Titrimetry, Water, Hydrogen Bonding, Stereoisomerism, Thermogravimetry, Microscopy, Electron, Scanning, Powders, Hydrate, Omeprazole, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e826dc092994a964616d3c3d50646099
https://pubmed.ncbi.nlm.nih.gov/19038514

المؤلفون: M. I. G. Moritz, Karen L. Lang, Eloir Paulo Schenkel, L. Baratto, Miguel S. B. Caro, Miriam Falkenberg

المصدر: Planta Medica. 73

مصطلحات موضوعية: Pharmacology, Synthetic drugs, Complementary and alternative medicine, Traditional medicine, business.industry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Medicine, Identification (biology), business, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8d12077aa41929bc572a397a9329cc6
https://doi.org/10.1055/s-2007-987062