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المؤلفون: Valentine Duru, Rekol Huy, Laurence Ma, David A. Fidock, Rotha Eam, Saorin Kim, Gregory Nuel, Benjamin Saintpierre, Christiane Bouchier, Sophy Chy, Didier Menard, Jean-Christophe Barale, Leila S. Ross, Odile Mercereau-Puijalon, Kaknika Loch, Eric Legrand, Benoit Witkowski, Frédéric Ariey, Johann Beghain, Chanra Khean, Rithea Leang, Anthony Bouillon, Nimol Khim, Malen Ken, Nimol Kloeung, Anais Domergue, Sopheakvatey Ke, Pascal Ringwald
المساهمون: Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), Columbia University Irving Medical Center (CUIMC), Génétique et Génomique des Insectes vecteurs, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Génomique (Plate-Forme) - Genomics Platform, Institut Pasteur [Paris] (IP), National Center for Malaria Control, Parasitology and Entomology, Ministry of Health of Cambodgia, Mathématiques Appliquées Paris 5 (MAP5 - UMR 8145), Université Paris Descartes - Paris 5 (UPD5)-Institut National des Sciences Mathématiques et de leurs Interactions (INSMI)-Centre National de la Recherche Scientifique (CNRS), Global Malaria Programme, Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Département Parasites et Insectes vecteurs - Department of Parasites and Insect Vectors, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by the Institut Pasteur in Cambodia, Institut Pasteur Paris, and WHO. DAF gratefully acknowledges partial funding for this work from the National Institutes of Health (NIH, R01 AI109023 and AI124678). LSR is a recipient of an NIH NRSA fellowship F32 AI120578. OM-P acknowledges funding from the French Government’s Investissement d’Avenir programme, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (grant number ANR-10-LABX-62-IBEID). VD was supported by a doctoral fellowship from the International Division, Institut Pasteur., We thank all patients enrolled in the therapeutic efficacy studies, the health centres’ staff, and the members of the National Center for Parasitology, Entomology and Malaria Control in Cambodia for their support. We are grateful to Daniel E Goldberg (Washington University School of Medicine, St Louis, MI, USA) for providing anti-plasmepsin 2 antibody., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Legrand, Eric, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Institut Pasteur du Cambodge-Réseau International des Instituts Pasteur ( RIIP ), Columbia University Medical Center ( CUMC ), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), Microbiologie structurale - Structural Microbiology, Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Génomique (Plate-Forme), Institut Pasteur [Paris], Mathématiques Appliquées à Paris 5 ( MAP5 - UMR 8145 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National des Sciences Mathématiques et de leurs Interactions-Centre National de la Recherche Scientifique ( CNRS ), WHO(OMS), Département Parasites et Insectes vecteurs, Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), ANR-10-LABX-62-IBEID,IBEID,Laboratoire d'Excellence 'Integrative Biology of Emerging Infectious Diseases' ( 2010 ), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: The Lancet. Infectious Diseases
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, In Press, Corrected Proof, 〈http://www.sciencedirect.com/science/article/pii/S1473309916304157〉. 〈10.1016/S1473-3099(16)30415-7〉
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩مصطلحات موضوعية: 0301 basic medicine, [ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, DNA Copy Number Variations, medicine.medical_treatment, Plasmodium falciparum, 030106 microbiology, Plasmepsin, Dihydroartemisinin, Drug resistance, Biology, Article, Antimalarials, 03 medical and health sciences, Piperaquine, parasitic diseases, Genotype, medicine, Aspartic Acid Endopeptidases, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, phenotype–genotype, Treatment Failure, Malaria, Falciparum, Genetic Association Studies, Genetics, biology.organism_classification, Artemisinins, Drug Resistance, Multiple, 3. Good health, Multiple drug resistance, Multidrug-resistant parasites, Infectious Diseases, Genetic marker, Quinolines, Cambodia, [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Biomarkers
وصف الملف: application/force-download
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المؤلفون: Benoit Witkowski, Hans-Peter Fuehrer, Garib Das Thakur, Céline Barnadas, Djibrine Djalle, Michael Ramharter, Mindy Leelawong, Wasif Ali-Khan, Harald Noedl, Bouasy Hongvanthong, Mohammad Shafiul-Alam, Hypolite Muhindo-Mavoko, Abdillahi Mohamed Hassan, Judith Straimer, Nimol Khim, Kigbafori D. Silué, Kaknika Loch, Barbara H. Stokes, Maria Dorina Bustos, Laura Berne, Dylan R. Pillai, Ayola A. Adegnika, Lin Hua Tang, Rotha Eam, Saorin Kim, Alioune Dieye, Mei Li, Carole E. Eboumbou-Moukoko, Lydie Canier, Marian Warsame, Didier Menard, David A. Fidock, Yap Boum, Lyndes Wini, Abdiqani Sheikh-Omar, Patrick Tshibangu-Wa-Tshibangu, Maman Laminou Ibrahim, Mohammad Jahirul-Karim, Malen Ken, Monique A. Dorkenoo, Sócrates Herrera, Odile Mercereau-Puijalon, Lise Musset, Valentine Duru, Eric Legrand, Maniphone Khanthavong, Pascal Ringwald, Bruno Pradines, Sandrine Houzé, Rachida Tahar, Olukemi K. Amodu, Johann Beghain, Sandie Menard, Liwang Cui, Colin J. Sutherland, Jun Hu Chen, Kesara Na-Bangchang, Khin Lin, Michael Nambozi, Rithea Leang, Jean Christophe Barale, Milijaona Randrianarivelojosia, Marcus V. G. Lacerda, Sophy Chy, Frédéric Ariey, Jean-Bosco Ouédraogo, Isabelle Morlais, Maria de Fátima Ferreira-da-Cruz, Lubin Jiang, Christophe Rogier, Jun Cao, Peter G. Kremsner, Bui Quang-Phuc, Inès Vigan-Womas, Din Syafruddin, Jetsumon Sattabongkot, Shigeyuki Kano, Abebe A. Fola, Louis Collet, Karamoko Niaré, Thierry Fandeur, Sedigheh Zakeri, Sodiomon B. Sirima, Antoine Berry, Jean Baptiste Mazarati, Fe Espino, Ghulam Rahim-Awab, Chanra Khean, Offianan Andre Toure
المساهمون: Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), Génétique et Génomique des Insectes vecteurs, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Centre de Recherche Médicale de Lambaréné, Albert Schweitzer, Leiden University Medical Center (LUMC), Universiteit Leiden, International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), University of Ibadan, Nangarhar University, Mahidol University [Bangkok], The Walter and Eliza Hall Institute of Medical Research (WEHI), University of Melbourne, Papua New Guinea Institute for Medical Research (PNGIMR), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Mbarara University of Science and Technology [Mbarara] (MUST), Epicentre Ouganda [Mbarara] [Médecins Sans Frontières], Epicentre [Paris] [Médecins Sans Frontières], World Health Organization (WHO), country office for Thailand, Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), JiangSu University, National Institute of Parasitic Diseases, Center for Disease Control, China, Centre Hospitalier de Mayotte, Pennsylvania State University (Penn State), Penn State System, Epidemiology and Disease Control division (EDCD), Ministry of Public Health [Nepal], Institut Pasteur de Dakar, Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), Institut Pasteur de Bangui, Université de Lomé [Togo], Université de Douala, Centre Pasteur du Cameroun, Research Institute for Tropical Medicine, Centre International de Recherches Médicales de Franceville (CIRMF), Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ), University of Gondar, Institute of Parasitology [Vienna], University of Veterinary Medicine, Vienna, World Health Organisation (WHO), country office for Somalia, Caucaseco scientific research center = Centro de Investigación Científica Caucaseco, National Center for Malariology, Parasitology and Entomology, Ministry of Health [Mozambique], Hôpital Bichat - Claude Bernard, Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (MERIT - UMR_D 216), Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5), Centre de Recherche Médicale et Sanitaire (Niamey, Niger) (CERMES), Directorate General of Health Services (DGHS), Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), National Center for Global Health and Medicine [Japan] (NCGM), Institut Pasteur du Laos, Instituto Leônidas e Maria Deane - Fiocruz Amazônia [Manaus, Brésil] (ILMD), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD), National Center for Malaria Control, Parasitology and Entomology, Ministry of Health of Cambodgia, Henry M. Jackson Foundation for the Advancement of Military Medicine (HJM), U.S. Naval Medical Research, The Department of Medical Research (Upper Myanmar), Rwanda Biomedical Center (RBC), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement [Yaoundé, Cameroun] (IRD [Cameroun]), Institut de Recherche pour le Développement (IRD), University of Kinshasa (UNIKIN), University of Antwerp (UA), Institut Pasteur de la Guyane, Thammasat University (TU), Tropical Diseases Research Center (TDRC), Université de Bamako, Medizinische Universität Wien = Medical University of Vienna, Institut de Recherche en Sciences de la Santé (IRSS) / Centre Muraz, Medicines for Malaria Venture (MMV), Université de Genève = University of Geneva (UNIGE), Global Malaria Programme, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National de Référence du Paludisme, Institut Pasteur de Madagascar, Ministry of Health and Human Services [Somalia], Centre Suisse de Recherches Scientifiques en Cote d'Ivoire [Abidjan] (CSRS-CI), Université Félix Houphouët-Boigny (UFHB), Groupe de recherche action en santé (GRAS), London School of Hygiene and Tropical Medicine (LSHTM), University of Hasanuddin, Eijkman Institute for Molecular Biology [Jakarta], Institut Pasteur de Côte d'Ivoire, Ministry of Health and Medical Services, Institut Pasteur d'Iran, Centre National de Référence du Paludisme [Cayenne, Guyane française] (CNR - laboratoire associé), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Columbia University Irving Medical Center (CUIMC), Institut de Recherche Biomédicale des Armées [Antenne Marseille] (IRBA), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5), Supported by the Institut Pasteur Paris, Institut Pasteur International Division, Institut Pasteur Cambodia, and the World Health Organization, by a grant (ANR-10-LABX-62-IBEID) from the French Government Investissement d’Avenir program, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases', a grant from Natixis Banques, a grant (R01I109023, to Dr. Fidock) from the National Institutes of Health, grants from the Fiocruz Fundação Oswaldo Cruz, Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro, Fundação de Amparo à Pesquisa do Estado do Amazonas, the Brazilian National Council for Scientific and Technological Development, the Agence Nationale de la Recherche (13-BSV3-0018-01 and11-BSV7-009-01), the Austrian Federal Ministry of Science, Research, and Econo-my, the Calgary Laboratory Services, the Centre International de Recherches Médicales de Franceville, the European and Developing Countries Clinical Trials Partnership (CT-2004-31070-001), the Drugs for Neglected Diseases Initiative, the Else Kroener Fresenius Stiftung, the Holger Poehlmann Stiftung, the European Community African–European Research Initiative 'IDEA' (HEALTH-F3-2009-241642), the Fonds Wetenschappelijk Onderzoek, the Vlaamse Interuniversitaire Raad–Universitaire Ontwikkelingssamenwerking, the Belgian Technical Cooperation in Democratic Republic of Congo, the European Community Seventh Framework Program (FP7/2007-2013, 242095, and 223601), the European Commission (REGPOT-CT-2011-285837-STRONGER), the Ministère de la Santé Publique du Niger (Laboratoire National de Référence Résistance aux Antipaludiques), the Foundation of National Science and Technology Major Program (2012ZX10004-220), the French Ministry of Health (Institut National de Veille Sanitaire), the Global Fund to Fight AIDS, Tuberculosis and Malaria, the 5% Initiative program (French Ministry of Foreign Affairs, France Expertise Internationale, 12INI109), the Institut Pasteur de Madagascar, the Government of the Philippines, the Institut de Recherche pour le Développement, the Foundation des Treilles, the Délégation Générale pour l’Armement (PDH-2-NRBC-4-B1-402), the Institut Pasteur de Bangui, the International Society for Health Research and Training, the Malaria Research Initiative Bandarban, Vienna, International Centre for Diarrhoeal Disease Research, Bangladesh, the Médecins sans Frontières (Centre Opérationnel Paris, France), Medicines for Malaria Venture, the National Research Council of Thailand, the Thammasat University, the National Natural Science Foundation of China (81271870, 81361120405, and 81271863), the Natural Science Foundation of Jiangsu Province (BK20130114 and BK20150001), the Jiangsu Science and Technology Department (BM2015024), the National Institutes of Health (R01 AI11646601, AI109023, and ICEMR U19AI089702, U19AI089672), the Pasteur Institute of Iran, the Malaria Division of the Iranian Center for Diseases Management and Control, Public Health England (Malaria Reference Service Contract), the Government of Rwanda, the U.S. Department of Defense Armed Forces Health Surveillance Center, Global Emerging Infections Surveillance and Response System (P0463-14-N6), the Fogarty International Center of the National Institutes of Health training (D43 TW007393), the Mahidol-Oxford Research Unit, the Government of Japan (Science and Technology Agency, Agency for Medical Research and Development, Japan International Cooperation Agency, and Science and Technology Research Partnership for Sustainable Development), and the President’s Malaria Initiative of the U.S. Agency for International Development., The KARMA Consortium, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-13-BSV3-0018,MALARTRES,Résistance de Plasmodium aux antipaludiques de la famille des artémisinines(2013), ANR-13-BSV7-0009,NEBEDIV,Le rôle des ennemis naturels dans la diversité béta des arbres tropicaux(2013), European Project: CT-2004-31070-001,EDCCTP, European Project: HEALTH-F3-2009-24164,IDEA, European Project: FP7/2007-2013, 24209,FP7, European Project: FP7/2007-2013, 22360,FP7, European Project: 285837,EC:FP7:REGPOT,FP7-REGPOT-2011-1,STRONGER(2011), European Project: 242095,EC:FP7:HEALTH,FP7-HEALTH-2009-single-stage,EVIMALAR(2009), European Project: 223601,EC:FP7:HEALTH,FP7-HEALTH-2007-B,MALVECBLOK(2009), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), CHU Toulouse [Toulouse], Fundação Oswaldo Cruz (FIOCRUZ), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Genève (UNIGE), INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Centre National de Référence du Paludisme [Cayenne, Guyane française] (CNR), Université Paris Diderot - Paris 7 (UPD7)-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Eberhard Karls Universität Tübingen, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Centre International de Recherches Médicales de Franceville, Caucaseco scientific research center, Mère et enfant face aux infections tropicales (MERIT - UMR_D 216), National Center for Global Health and Medicine (NCGM), Instituto Leônidas e Maria Deane (ILMD), Centre de Physiopathologie Toulouse Purpan ex IFR 30 et IFR 150 (CPTP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement [Yaoundé], Centre Suisse de Recherches Scientifiques en Côte d'Ivoire, Eijkman Institute for Molecular Biology, Laboratoire de Parasitologie, Centre National de Référence du Paludisme - Région Antilles-Guyane, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-WHO Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), ANR-10-LABX-62-IBEID,IBEID,Laboratoire d'Excellence 'Integrative Biology of Emerging Infectious Diseases'(2010), Van geertruyden, Jean-Pierre, KARMA Consortium
المصدر: New England Journal of Medicine
New England Journal of Medicine, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩
New England Journal of Medicine, Massachusetts Medical Society, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩
The New England journal of medicineمصطلحات موضوعية: 0301 basic medicine, Nonsynonymous substitution, MESH: Sequence Analysis, DNA, Endemic Diseases, MESH: Asia, Southeastern, Drug Resistance, Protozoan Proteins, Drug resistance, MESH: Genotype, Lactones, 0302 clinical medicine, Genotype, Artemisinin, Malaria, Falciparum, MESH: Protozoan Proteins, Asia, Southeastern, MESH: Plasmodium falciparum, Genetics, biology, MESH: Malaria, Falciparum, General Medicine, Artemisinins, MESH: China, 3. Good health, MESH: Endemic Diseases, MESH: Drug Resistance, Algorithms, MESH: Lactones, medicine.drug, China, MESH: Mutation, 030231 tropical medicine, 030106 microbiology, Plasmodium falciparum, MESH: Algorithms, 03 medical and health sciences, parasitic diseases, MESH: Artemisinins, MESH: Polymorphism, Genetic, medicine, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Allele, Polymorphism, Genetic, MESH: Humans, Haplotype, Sequence Analysis, DNA, medicine.disease, biology.organism_classification, Virology, Mutation, Human medicine, Malaria
وصف الملف: application/pdf; pdf
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المؤلفون: Anais Domergue, Odile Mercereau-Puijalon, Rithea Leang, Malen Ken, Dysoley Lek, Johann Beghain, Benoit Witkowski, Nimol Khim, Kaknika Loch, Rekol Huy, Frédéric Ariey, Saorin Kim, Chanra Khean, Nimol Kloeung, Valentine Duru, Rotha Eam, Philippe J Guerin, Sophy Chy, Didier Menard, Sopheakvatey Ke
المساهمون: Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), National Center for Parasitology, Entomology and Malaria Control [Phnom Penh, Cambodia] (CNM), Département Parasites et Insectes vecteurs - Department of Parasites and Insect Vectors, Institut Pasteur [Paris], WorldWide Antimalarial Resistance Network (WWARN), University of Oxford [Oxford]-Churchill Hospital Oxford Centre for Haematology, Centre for Tropical Medicine and Global Health [Oxford, UK], Nuffield Department of Medicine [Oxford, UK] (Big Data Institute), University of Oxford [Oxford]-University of Oxford [Oxford], This work was funded by grants from Institut Pasteur du Cambodge, USAID and BMGF through the World Health Organization, and Institut Pasteur Paris. PJG is member of the Worldwide Antimalarial Resistance Network supported by the Bill and Melinda Gates Foundation. VD is supported by a doctoral fellowship from the International Division, Institut Pasteur., We thank all patients enrolled in the therapeutic efficacy studies, the health centres staff and the staff from the National Center for Parasitology, Entomology and Malaria Control in Cambodia for their support. We are grateful to Joel Tarning (Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand, Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom) who performed the piperaquine concentration measurements., Institut Pasteur [Paris] (IP), University of Oxford-Churchill Hospital Oxford Centre for Haematology, University of Oxford-University of Oxford
المصدر: BMC Medicine
BMC Medicine, BioMed Central, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩مصطلحات موضوعية: Male, Oncology, MESH: Treatment Failure, Piperaquine resistance, Pharmacology, Dihydroartemisinin/piperaquine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Animals, Prospective Studies, Malaria, Falciparum, Artemisinin, Prospective cohort study, Ex vivo testing, MESH: Plasmodium falciparum, Artemisinin combination therapies, MESH: Treatment Outcome, Medicine(all), 0303 health sciences, biology, MESH: Malaria, Falciparum, General Medicine, Artemisinins, 3. Good health, Survival Rate, Treatment Outcome, Artemisinin resistance, MESH: Young Adult, Quinolines, Female, Cambodia, MESH: Quinolines, Research Article, medicine.drug, Adult, Falciparum, medicine.medical_specialty, Adolescent, MESH: Survival Rate, Plasmodium falciparum, Antimalarials, Young Adult, 03 medical and health sciences, Internal medicine, Piperaquine, parasitic diseases, MESH: Artemisinins, medicine, Animals, Humans, Parasites, Survival rate, In-vitro testing, MESH: Parasites, Retrospective Studies, 030304 developmental biology, MESH: Adolescent, MESH: Humans, 030306 microbiology, business.industry, MESH: Cambodia, MESH: Adult, MESH: Retrospective Studies, medicine.disease, biology.organism_classification, MESH: Antimalarials, MESH: Male, MESH: Prospective Studies, Malaria, Treatment failure, business, MESH: Female, Ex vivo
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
مصطلحات موضوعية: body regions, parasitic diseases, humanities
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
مصطلحات موضوعية: parasitic diseases
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
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المؤلفون: Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
مصطلحات موضوعية: parasitic diseases
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المؤلفون: Sambunny Uk, Lies Durnez, Nimol Khim, Lydie Canier, Charlotte Gryseels, Chanra Khean, Mao Sokny, Sochantha Tho, Boukheng Thavrin, Sophy Chy, Saorin Kim, Rotha Eam, Vincent Sluydts, Marc Coosemans, Dany Dourng, Didier Menard, Sovannaroath Siv, Karel Van Roey, Malen Ken, Hokkean Lim, Somony Heng, Char Meng Chuor, Pascal Masse-Navette, Vincent Deubel, Koen Peeters Grietens, Kaknika Loch
المصدر: Malaria Journal
Malaria journalمصطلحات موضوعية: Plasmodium, Time Factors, Plasmodium vivax, Plasmodium malariae, Biology, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, parasitic diseases, medicine, Humans, Mass Screening, Asymptomatic Infections, Mass screening, Molecular Epidemiology, Research, Anopheles, Plasmodium falciparum, biology.organism_classification, Plasmodium ovale, medicine.disease, Virology, Malaria, Cross-Sectional Studies, Infectious Diseases, Molecular Diagnostic Techniques, Immunology, Carrier State, Parasitology, Sample collection, Human medicine, Cambodia
وصف الملف: pdf