نتائج البحث - "KEIRNS, J"

1

Academic Journal

The IQ-CSRC prospective clinical Phase 1 study: "Can early QT assessment using exposure response analysis replace the thorough QT study?"

المؤلفون: Darpo, B, Sarapa, N, Garnett, C, Benson, C, Dota, C, Ferber, G, Jarugula, V, Johannesen, L, Keirns, J, Krudys, K, Ortemann-Renon, C, Riley, S, Rogers-Subramaniam, D, Stockbridge, N

المصدر: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. 19(1):70-81

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:128279555

View record in SwePub

Full Text Finder

2

Academic Journal

Can Bias Evaluation Provide Protection Against False-Negative Results in QT Studies Without a Positive Control Using Exposure-Response Analysis?

المؤلفون: Ferber, G, Zhou, MJ, Dota, C, Garnett, C, Keirns, J, Malik, M, Stockbridge, N, Darpo, B

المصدر: Journal of clinical pharmacology. 57(1):85-95

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:135033238

3

Academic Journal

Implications of the IQ-CSRC Prospective Study: Time to Revise ICH E14

المؤلفون: Darpo, B, Garnett, C, Keirns, J, Stockbridge, N

المصدر: Drug safety. 38(9):773-780

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:131957571

4

Academic Journal

Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase

المؤلفون: Darpo, B, Benson, C, Dota, C, Ferber, G, Garnett, C, Green, CL, Jarugula, V, Johannesen, L, Keirns, J, Krudys, K, Liu, J, Ortemann-Renon, C, Riley, S, Sarapa, N, Smith, B, Stoltz, RR, Zhou, M, Stockbridge, N

المصدر: Clinical pharmacology and therapeutics. 97(4):326-335

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:130902159

5

Academic Journal

Cardiac Safety Research Consortium: can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward

المؤلفون: Darpo, B, Garnett, C, Benson, CT, Keirns, J, Leishman, D, Malik, M, Mehrotra, N, Prasad, K, Riley, S, Rodriguez, I, Sager, P, Sarapa, N, Wallis, R

المصدر: American heart journal. 168(3):262-272

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:129677477

6

Academic Journal

QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization

المؤلفون: Keirns, J, Desai, A, Kowalski, D, Lademacher, C, Mujais, S, Parker, B, Schneidkraut, MJ, Townsend, R, Wojtkowski, T, Yamazaki, T, Yen, M, Kowey, PR

المصدر: Clinical Pharmacology & Therapeutics ; volume 101, issue 6, page 782-790 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.620
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcpt.620
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.620

View record in BASE

7

Academic Journal

A Phase 1, Randomized Ascending Single-Dose Study of Antagonist Anti-Human CD40 ASKP1240 in Healthy Subjects

المؤلفون: Goldwater, R., Keirns, J., Blahunka, P., First, R., Sawamoto, T., Zhang, W., Kowalski, D., Kaibara, A., Holman, J.

المساهمون: Astellas Pharma Global Development

المصدر: American Journal of Transplantation ; volume 13, issue 4, page 1040-1046 ; ISSN 1600-6135

الاتاحة: http://dx.doi.org/10.1111/ajt.12082
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fajt.12082
https://api.elsevier.com/content/article/PII:S1600613522259097?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1600613522259097?httpAccept=text/plain
http://onlinelibrary.wiley.com/wol1/doi/10.1111/ajt.12082/fullpdf

View record in BASE

8

Academic Journal

Once-Daily Tacrolimus Extended-Release Formulation: 1-Year Post-Conversion in Stable Pediatric Liver Transplant Recipients

المؤلفون: Heffron, T.G., Pescovitz, M.D., Florman, S., Kalayoglu, M., Emre, S., Smallwood, G., Wisemandle, K., Anania, C., Dhadda, S., Sawamoto, T., Keirns, J., Fitzsimmons, W., First, M.R.

المصدر: American Journal of Transplantation ; volume 7, issue 6, page 1609-1615 ; ISSN 1600-6135

الاتاحة: http://dx.doi.org/10.1111/j.1600-6143.2007.01803.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1600-6143.2007.01803.x
https://api.elsevier.com/content/article/PII:S160061352202771X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S160061352202771X?httpAccept=text/plain
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1600-6143.2007.01803.x/fullpdf

View record in BASE

9

Academic Journal

Steady-State Pharmacokinetics of Micafungin and Voriconazole after Separate and Concomitant Dosing in Healthy Adults

المؤلفون: Keirns, J., Sawamoto, T., Holum, M., Buell, D., Wisemandle, W., Alak, A.

المصدر: Antimicrobial Agents and Chemotherapy ; volume 51, issue 2, page 787-790 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.00673-06
https://journals.asm.org/doi/pdf/10.1128/AAC.00673-06

View record in BASE

10

Academic Journal

Pharmacokinetics of nevirapine: initial single-rising-dose study in humans

المؤلفون: Cheeseman, S H, Hattox, S E, McLaughlin, M M, Koup, R A, Andrews, C, Bova, C A, Pav, J W, Roy, T, Sullivan, J L, Keirns, J J

المصدر: Antimicrobial Agents and Chemotherapy ; volume 37, issue 2, page 178-182 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.37.2.178
https://journals.asm.org/doi/pdf/10.1128/AAC.37.2.178

View record in BASE

11

Academic Journal

Microwave Spectrum of Acryloyl Fluoride.

المؤلفون: Keirns, J. J., Curl, R. F.

المصدر: Journal of Chemical Physics; Apr1968, Vol. 48 Issue 8, p3773-3778, 6p

12

Academic Journal

THU0256 Pharmacodynamics of ASP015K, A Novel Janus Kinase Inhibitor, in Healthy Volunteers

المؤلفون: Zhu, T., Valluri, U., Lewand, M., Cao, Y., Cho, K., Holman, J., Sawamoto, T., Keirns, J.

المصدر: Annals of the Rheumatic Diseases ; volume 72, issue Suppl 3, page A252.1-A252 ; ISSN 0003-4967 1468-2060

الاتاحة: http://dx.doi.org/10.1136/annrheumdis-2013-eular.784
https://syndication.highwire.org/content/doi/10.1136/annrheumdis-2013-eular.784

View record in BASE

13

Academic Journal

AB0364 Pharmacokinetics, safety, and tolerability of asp015k, a novel janus kinase inhibitor, in healthy volunteers

المؤلفون: Zhu, T., Sawamoto, T., Valluri, U., Lewand, M., Cao, Y., Swan, S., Lasseter, K., Matson, M., Holman, J., Keirns, J.

المصدر: Annals of the Rheumatic Diseases ; volume 72, issue Suppl 3, page A898.3-A899 ; ISSN 0003-4967 1468-2060

الاتاحة: http://dx.doi.org/10.1136/annrheumdis-2013-eular.2686
https://syndication.highwire.org/content/doi/10.1136/annrheumdis-2013-eular.2686

View record in BASE

14

Academic Journal

Proarrhythmic Safety of Repeat Doses of Mirabegron in Healthy Subjects: A Randomized, Double-Blind, Placebo-, and Active-Controlled Thorough QT Study

المؤلفون: Malik, M, van Gelderen, E M, Lee, J H, Kowalski, D L, Yen, M, Goldwater, R, Mujais, S K, Schaddelee, M P, de Koning, P, Kaibara, A, Moy, S S, Keirns, J J

المصدر: Clinical Pharmacology & Therapeutics ; volume 92, issue 6, page 696-706 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1038/clpt.2012.181

View record in BASE

15

Academic Journal

No pharmacokinetic interaction between ipragliflozin and sitagliptin, pioglitazone, or glimepiride in healthy subjects

المؤلفون: Smulders, R. A., Zhang, W., Veltkamp, S. A., van Dijk, J., Krauwinkel, W. J. J., Keirns, J., Kadokura, T.

المصدر: Diabetes, Obesity and Metabolism ; volume 14, issue 10, page 937-943 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/j.1463-1326.2012.01624.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1463-1326.2012.01624.x
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1463-1326.2012.01624.x/fullpdf

View record in BASE

16

Academic Journal

Disposition and Mass Balance of [ 14 C]Vernakalant After Single Intravenous and Oral Doses in Healthy Volunteers

المؤلفون: L. Mao, Z., Alak, A., J. Wheeler, J., Keirns, J.

المصدر: Drug Metabolism Letters ; volume 5, issue 2, page 114-125 ; ISSN 1872-3128

الاتاحة: http://dx.doi.org/10.2174/187231211795305249
http://eurekaselect.com/article/download/94414

View record in BASE

17

Academic Journal

Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant

المؤلفون: Hiemenz, J., Cagnoni, P., Simpson, D., Devine, S., Chao, N., Keirns, J., Lau, W., Facklam, D., Buell, D.

المصدر: Open Access Publications

وصف الملف: application/pdf

Relation: https://digitalcommons.wustl.edu/open_access_pubs/2358; https://digitalcommons.wustl.edu/context/open_access_pubs/article/3367/viewcontent/PharmacokineticAndMaximumToleratedDoseStudy.pdf

الاتاحة: https://digitalcommons.wustl.edu/open_access_pubs/2358
https://doi.org/10.1128/AAC.49.4.1331-1336.2005
https://digitalcommons.wustl.edu/context/open_access_pubs/article/3367/viewcontent/PharmacokineticAndMaximumToleratedDoseStudy.pdf

View record in BASE

18

Academic Journal

Nevirapine induces both CYP3A4 and CYP2B6 metabolic pathways

المؤلفون: LAMSON, M, MACGREGOR, T, RISKA, P, ERICKSON, D, MAXFIELD, P, ROWLAND, L, GIGLIOTTI, M, ROBINSON, P, AZZAM, S, KEIRNS, J

المصدر: Clinical Pharmacology & Therapeutics ; volume 65, issue 2, page 137-137 ; ISSN 0009-9236

الاتاحة: http://dx.doi.org/10.1016/s0009-9236(99)80079-4

View record in BASE

19

Academic Journal

A comparison of 1- and 2-cell ova production by F2 50% Meishan versus F1 White line gilts

المؤلفون: Martin, M.J., Merriman, C., Freeman, B., Merriman, J., Keirns, J., Pumfrey, R.A.

المصدر: Theriogenology ; volume 39, issue 3, page 763-769 ; ISSN 0093-691X

الاتاحة: http://dx.doi.org/10.1016/0093-691x(93)90259-8
https://api.elsevier.com/content/article/PII:0093691X93902598?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:0093691X93902598?httpAccept=text/plain

View record in BASE

20

Academic Journal

Oral pharmacokinetics of pirenzepine in patients with chronic renal insufficiency, failure, and maintenance haemodialysis

المؤلفون: MacGregor, T., Matzek, K., Keirns, J., Vinocur, M., Chonko, A.

المصدر: European Journal of Clinical Pharmacology ; volume 38, issue 4, page 405-406 ; ISSN 0031-6970 1432-1041

الاتاحة: http://dx.doi.org/10.1007/bf00315586
http://link.springer.com/content/pdf/10.1007/BF00315586.pdf
http://link.springer.com/article/10.1007/BF00315586/fulltext.html
http://link.springer.com/content/pdf/10.1007/BF00315586

View record in BASE

تنقيح النتائج