المؤلفون: Juliana Maynard, Sally-Ann Emmas, Francois-Xavier Ble, Herve Barjat, Emily Lawrie, Urs Hancox, Urszula M Polanska, Alison Pritchard, Kevin Hudson

المصدر: PLoS ONE, Vol 12, Iss 8, p e0183048 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5555689?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/80f605b879c64cb1be9488d813ac5c25

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ea91e81a67f3f040a1bb9626f1a13
https://doi.org/10.1158/1535-7163.22498635

المؤلفون: Simon T. Barry, Francisco Cruzalegui, Susan E. Critchlow, Teresa Klinowska, Marie Cumberbatch, Alvaro Avivar-Valderas, Radoslaw Polanski, Carol Lenaghan, Catherine Eberlein, Catherine Trigwell, Juliana Maynard, Oona Delpuech, Ursula Hancox, Urszula M. Polanska, James T. Lynch

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a49696169a1bdafab82b251d9a41f65
https://doi.org/10.1158/1535-7163.22505517.v1

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26adbc826f9cc85329a52ca84cf29cd2
https://doi.org/10.1158/1535-7163.22498644.v1

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aca16ca8976daf5767839bc44394ac
https://doi.org/10.1158/1535-7163.22498647

المؤلفون: Simon T. Barry, Francisco Cruzalegui, Susan E. Critchlow, Teresa Klinowska, Marie Cumberbatch, Alvaro Avivar-Valderas, Radoslaw Polanski, Carol Lenaghan, Catherine Eberlein, Catherine Trigwell, Juliana Maynard, Oona Delpuech, Ursula Hancox, Urszula M. Polanska, James T. Lynch

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3b3a8efc07d530f0362f410fd03bbc96
https://doi.org/10.1158/1535-7163.c.6538098.v1

المؤلفون: Simon T. Barry, Francisco Cruzalegui, Susan E. Critchlow, Teresa Klinowska, Marie Cumberbatch, Alvaro Avivar-Valderas, Radoslaw Polanski, Carol Lenaghan, Catherine Eberlein, Catherine Trigwell, Juliana Maynard, Oona Delpuech, Ursula Hancox, Urszula M. Polanska, James T. Lynch

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91db55cea79f8877939d98d6dd7b2313
https://doi.org/10.1158/1535-7163.22505511

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3112b5ae732cb14b1fb9210be4bf92
https://doi.org/10.1158/1535-7163.22498638.v1

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59eda9af138e0854ae982cf0930bd6d1
https://doi.org/10.1158/1535-7163.22498641

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0694b929ca9bbf6674a0e14b9be57b20
https://doi.org/10.1158/1535-7163.22498650.v1

المؤلفون: Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cc27e4c5c098c582d92d81ddb5859a
https://doi.org/10.1158/1535-7163.c.6535935

المؤلفون: Sally A. Peyman, Malcolm Haddrick, William Townley, Michael Fairclough, Elizabeth M. A. Valleley, Nicola Ingram, Antonia Wierzbicki, Richard J. Bushby, Radwa H. Abou-Saleh, Stephen D. Evans, Pamela F. Jones, Gemma Marston, Darren Treanor, Milene Volpato, Antonia Charalambous, Juliana Maynard, Neil H. Thomson, Laura E. McVeigh, J. Anthony Evans, Jorge L Jimenez-Macias, A Wright, P. Louise Coletta, Peter B Simpson, Benjamin R. G. Johnson, Steven Freear, Alexander F. Markham, James R. McLaughlan, Paul M. Loadman

المصدر: Fairclough, M 2020, ' Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumour drug accumulation and limiting bioavailability and toxicity in normal tissues ', Theranostics, vol. 10, no. 4 . https://doi.org/10.7150/thno.49670
Ingram, N, McVeigh, L E, Abou-Saleh, R H, Maynard, J, Peyman, S A, McLaughlan, J R, Fairclough, M, Marston, G, Valleley, E M A, Jimenez-Macias, J L, Charalambous, A, Townley, W, Haddrick, M, Wierzbicki, A, Wright, A, Volpato, M, Simpson, P B, Treanor, D E, Thomson, N H, Loadman, P M, Bushby, R J, Johnson, B R G, Jones, P F, Evans, J A, Freear, S, Markham, A F, Evans, S D & Coletta, P L 2020, ' Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues ', Theranostics, vol. 10, no. 24, pp. 10973-10992 . https://doi.org/10.7150/thno.49670
Theranostics

مصطلحات موضوعية: Drug, Biodistribution, media_common.quotation_subject, Biological Availability, Medicine (miscellaneous), Antineoplastic Agents, colorectal cancer, 02 engineering and technology, Pharmacology, Irinotecan, Microbubble, 03 medical and health sciences, Drug Delivery Systems, 0302 clinical medicine, Therapeutic index, Cell Line, Tumor, medicine, Humans, Tissue Distribution, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), media_common, Liposome, Microbubbles, ultrasound, business.industry, nanoformulation, Microfluidic Analytical Techniques, 021001 nanoscience & nanotechnology, Combined Modality Therapy, Vascular Endothelial Growth Factor Receptor-2, Xenograft Model Antitumor Assays, VEGFR2, Ultrasonic Waves, Positron-Emission Tomography, 030220 oncology & carcinogenesis, Pharmacodynamics, Drug delivery, Female, Colorectal Neoplasms, 0210 nano-technology, business, Research Paper, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8743562efc9f20857e1d1305e425ca8f
https://www.research.manchester.ac.uk/portal/en/publications/ultrasoundtriggered-therapeutic-microbubbles-enhance-the-efficacy-of-cytotoxic-drugs-by-increasing-circulation-and-tumour-drug-accumulation-and-limiting-bioavailability-and-toxicity-in-normal-tissues(d99d292e-9ff7-4039-a343-5bfeafca0d06).html

المؤلفون: Sally Price, Peter B Simpson, Juliana Maynard, M. C. McElroy

المصدر: Idiopathic interstitial pneumonias.

مصطلحات موضوعية: Drug, Fluorodeoxyglucose positron emission tomography, Anti fibrotic, business.industry, media_common.quotation_subject, Cancer research, Biomarker (medicine), Medicine, business, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e5ff482ac69467e2dcee6fbae8b1307c
https://doi.org/10.1183/13993003.congress-2020.3388

المؤلفون: Ursula Hancox, Carol Lenaghan, Marie Cumberbatch, Juliana Maynard, Alvaro Avivar-Valderas, Catherine B. Trigwell, Radoslaw Polanski, Teresa Klinowska, Susan E. Critchlow, Oona Delpuech, Catherine Anne Eberlein, Urszula M. Polanska, James T. Lynch, Simon T. Barry, Francisco Cruzalegui

المصدر: Molecular Cancer Therapeutics. 17:2309-2319

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Mice, Nude, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Fluorodeoxyglucose F18, In vivo, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, PTEN, Protein Kinase Inhibitors, Transcription factor, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Cell Nucleus, Aniline Compounds, biology, Kinase, Cell growth, Chemistry, TOR Serine-Threonine Kinases, Forkhead Box Protein O3, PTEN Phosphohydrolase, Cancer, medicine.disease, Protein Transport, Glucose, 030104 developmental biology, Oncology, Chromones, FOXO3, biology.protein, Cancer research, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bc79c12b4c0a2616e2ca44a140867d
https://doi.org/10.1158/1535-7163.mct-18-0183

المؤلفون: Philippa Hart, Juliana Maynard

المصدر: SLAS discovery : advancing life sciences RD. 25(2)

مصطلحات موضوعية: medicine.medical_specialty, Drug molecule, Biochemistry, Clinical success, Analytical Chemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Lack of efficacy, medicine, Animals, Humans, Medical physics, 030304 developmental biology, Pharmaceutical industry, 0303 health sciences, Drug discovery, business.industry, Target engagement, Molecular Imaging, 030220 oncology & carcinogenesis, Models, Animal, Molecular Medicine, business, Preclinical imaging, Target organ, Biomarkers, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9661ae659b705b5d4eac7866bde449
https://pubmed.ncbi.nlm.nih.gov/31885303

المؤلفون: Fabian Kiessling, Holger Grüll, Juliana Maynard, Benjamin Theek, Michal Neeman, Sarah Baetke, Felix Gremse, Ruth Knuechel, Sally-Ann Ricketts, Wiltrud Lederle, Twan Lammers, Diana Möckel, Josef Ehling

المصدر: The American Journal of Pathology. 184:431-441

مصطلحات موضوعية: Tumor angiogenesis, 0303 health sciences, Pathology, medicine.medical_specialty, X-ray microtomography, Angiogenesis, Blood volume, Biology, Pathology and Forensic Medicine, Neovascularization, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Immunohistochemistry, Tomography, medicine.symptom, Micro ct, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::78c33764b70badf4d2567077c8e5735e
https://doi.org/10.1016/j.ajpath.2013.10.014

المؤلفون: Juliana Maynard, Stewart Davis, Marietta Scott, Sally-Ann Ricketts, Andrew P. Holmes, Angela Sykes, Helen Powell, Jane Stewart, Guy Healing

المصدر: Journal of Applied Toxicology. 34:1368-1372

مصطلحات موضوعية: Reproducibility, medicine.medical_specialty, Longitudinal study, business.industry, Sedation, Ultrasound, Toxicology, Beagle, law.invention, Surgery, Lens (optics), Lens thickness, In utero, law, Ophthalmology, medicine, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::114dd9cccc0de05943f73acedf45a2f4
https://doi.org/10.1002/jat.2967

المؤلفون: Rajesh Odedra, Sylvie Guichard, Stephen R. Wedge, Juliana Maynard, Heather Keen, Aoife M. Shannon, Sally-Ann Ricketts, Armelle Logie

المصدر: Molecular Imaging and Biology. 16:421-430

مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Morpholines, Mice, Nude, mTORC1, mTORC2, Mice, MTOR Kinase Inhibitor AZD8055, Fluorodeoxyglucose F18, Glioma, Biomarkers, Tumor, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, PI3K/AKT/mTOR pathway, Vascular Endothelial Growth Factor Receptor-1, Brain Neoplasms, business.industry, TOR Serine-Threonine Kinases, medicine.disease, Oncology, Cancer research, Biomarker (medicine), Female, business, Preclinical imaging, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c0f0e4a26b37073cc43e62f26b87fd
https://doi.org/10.1007/s11307-013-0705-0

المؤلفون: Hervé Barjat, Urszula M. Polanska, Alison Pritchard, Sally-Ann Emmas, Kevin Hudson, Juliana Maynard, François-Xavier Blé, Urs Hancox, Emily Lawrie

المصدر: PLoS ONE, Vol 12, Iss 8, p e0183048 (2017)
PLoS ONE

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, Imaging biomarker, Physiology, Glucose uptake, Cancer Treatment, Phases of clinical research, lcsh:Medicine, Drug research and development, Pharmacology, Biochemistry, Diagnostic Radiology, Phosphatidylinositol 3-Kinases, Clinical trials, 0302 clinical medicine, Cell Signaling, Piperidines, Medicine and Health Sciences, Homeostasis, Enzyme-Linked Immunoassays, lcsh:Science, Tomography, Phosphoinositide-3 Kinase Inhibitors, Oxadiazoles, Multidisciplinary, medicine.diagnostic_test, Phase I clinical investigation, Radiology and Imaging, Effective dose (pharmacology), Blood Sugar, Body Fluids, Blood, Oncology, Positron emission tomography, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Anatomy, Research Article, Signal Transduction, Imaging Techniques, Mice, Nude, Neuroimaging, Research and Analysis Methods, Glucose Signaling, 03 medical and health sciences, Diagnostic Medicine, Fluorodeoxyglucose F18, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, Immunoassays, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Dose-Response Relationship, Drug, business.industry, lcsh:R, Biology and Life Sciences, Cell Biology, Xenograft Model Antitumor Assays, 030104 developmental biology, Pharmacodynamics, Clinical medicine, Positron-Emission Tomography, Immunologic Techniques, lcsh:Q, business, Biomarkers, Positron Emission Tomography, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548441491c6d17128ee282a1e90d6883
http://europepmc.org/articles/PMC5555689?pdf=render

المؤلفون: Sally-Ann Ricketts, Christelle Gendrin, Phillippa Dudley, Barry R. Davies, Juliana Maynard

المصدر: Molecular Imaging and Biology. 15:476-485

مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Time Factors, Mice, Nude, Phases of clinical research, Antineoplastic Agents, Mice, Fluorodeoxyglucose F18, Predictive Value of Tests, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, Pyrroles, Radiology, Nuclear Medicine and imaging, Phosphorylation, Protein Kinase Inhibitors, Protein kinase B, PI3K/AKT/mTOR pathway, Dose-Response Relationship, Drug, medicine.diagnostic_test, Akt inhibitor AZD5363, business.industry, Xenograft Model Antitumor Assays, Tumor Burden, Enzyme Activation, Dose–response relationship, Glucose, Pyrimidines, Treatment Outcome, Oncology, Drug development, Positron emission tomography, Positron-Emission Tomography, Cancer research, Biomarker (medicine), Female, business, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d39c5044cbb3d1886f82bafb10e70d8
https://doi.org/10.1007/s11307-013-0613-3