المؤلفون: Bethany Powell Gray, Linsley Kelly, Kady-Ann Steen-Burrell, Juliana M. Layzer, Rachel E. Rempel, Shahid M. Nimjee, Brian C. Cooley, Alice F. Tarantal, Bruce A. Sullenger

المصدر: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 440-451 (2023)

مصطلحات موضوعية: MT: Oligonucleotides: Diagnostics and Biosensors, aptamers, RNA, imaging, thrombosis, clot imaging, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123000124; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/1ee17a94201144fc8700f739b611a006

المؤلفون: Christopher R. Reed, Desiree Bonadonna, James C. Otto, Charles Griffin McDaniel, Charlene Vongai Chabata, Maragatha Kuchibhatla, James Frederiksen, Juliana M. Layzer, Gowthami M. Arepally, Bruce A. Sullenger, Elisabeth T. Tracy

المصدر: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 524-534 (2022)

مصطلحات موضوعية: anticoagulation, extracorporeal membrane oxygenation, pediatric surgery, mechanical support, heart failure, aptamers, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253121003140; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/d7436a28615d421ab29cdaa12ab5b3e2

المؤلفون: Shahid M Nimjee, Debra Wheeler, Stacy Nelson, Richard J Shea, Taegen Sullivan, Christina Mayer, Leo Pavliv, Juliana M Layzer, Jason Lickliter, Bruce Sullenger, Bruce Campbell, Richard C Becker

المصدر: Stroke. 54

مصطلحات موضوعية: Advanced and Specialized Nursing, Neurology (clinical), Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a851b5b851c76fcf3c96d2432b3fd710
https://doi.org/10.1161/str.54.suppl_1.94

المؤلفون: Korie Bush, Amy C. Yan, Keith Haynes, Juliana M. Layzer, Jonathan H. Zhou, Telmo Llanga, Bruce A. Sullenger

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2a9d8911097f813268bea790dfcee539
https://doi.org/10.2139/ssrn.4199638

المؤلفون: Imran Ozer, George A. Pitoc, Juliana M. Layzer, Angelo Moreno, Lyra B. Olson, Kyle D. Layzer, Angus M. Hucknall, Bruce A. Sullenger, Ashutosh Chilkoti

المصدر: Advanced materials (Deerfield Beach, Fla.). 34(10)

مصطلحات موضوعية: Mice, Mechanics of Materials, Polymers, Mechanical Engineering, Immunity, Animals, Anticoagulants, RNA, General Materials Science, Aptamers, Nucleotide, Polyethylene Glycols

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfa782582d91d2af0c8fc20c97c4b39
https://pubmed.ncbi.nlm.nih.gov/34994037

المؤلفون: Jenna Wilson, Debra G Wheeler, Laura J. Sommerville, David Dornbos, Kendyl Carlisle, Nicholas Venetos, Richard C. Becker, Shahid M Nimjee, Juliana M. Layzer, George A. Pitoc, Nicholas Musgrave, Allyson Huttinger, Spencer Talentino, Shoeb I. Khan, Holly Moody, Bruce A. Sullenger, Jay L. Zweier, Camille Bratton, Rachel E. Rempel, Matthew Joseph, Maureane Hoffman, Cheyenne Jones

المصدر: Mol Ther

مصطلحات موضوعية: Blood Platelets, Male, medicine.medical_specialty, Platelet Aggregation, Antidotes, Drug Evaluation, Preclinical, Oligonucleotides, Arterial Occlusive Diseases, Mice, 03 medical and health sciences, Dogs, Platelet Adhesiveness, 0302 clinical medicine, Fibrinolytic Agents, Von Willebrand factor, Internal medicine, von Willebrand Factor, Drug Discovery, Antithrombotic, Genetics, Animals, Humans, Medicine, Platelet, Myocardial infarction, Molecular Biology, Stroke, 030304 developmental biology, Whole blood, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, biology, business.industry, Vascular disease, Thrombosis, Aptamers, Nucleotide, medicine.disease, Healthy Volunteers, Mice, Inbred C57BL, 030220 oncology & carcinogenesis, Cardiology, biology.protein, Molecular Medicine, Original Article, Female, Carotid Artery Injuries, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4909ecd632d79e90e5038b60fb450
https://doi.org/10.1016/j.ymthe.2019.03.016

المؤلفون: Chandan K. Sen, Shahid M Nimjee, Allyson Huttinger, Bruce A. Sullenger, Debra G Wheeler, David Dornbos rd, Spencer Talentino, Cheyenne Jones, Nicholas Venetos, Camille Bratton, Juliana M. Layzer, Matthew Joseph, Nicholas Musgrave, Surya Gnyawali

المصدر: J Vis Exp

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Carotid arteries, General Chemical Engineering, Ferric Compounds, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Dogs, 0302 clinical medicine, Chlorides, Internal medicine, medicine, Animals, Humans, Thrombolytic Agent, Carotid Artery Thrombosis, Myocardial infarction, medicine.diagnostic_test, General Immunology and Microbiology, business.industry, General Neuroscience, Magnetic resonance imaging, Vascular System Injuries, medicine.disease, Thrombosis, Disease Models, Animal, 030104 developmental biology, Angiography, Cardiology, Medicine, business, 030217 neurology & neurosurgery, Large animal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa0e8357d6c5107b468f6cc855d277f
https://doi.org/10.3791/57981-v

المؤلفون: George A. Pitoc, Juliana M. Layzer, Alice F. Tarantal, Bruce A. Sullenger, Michael S. Hershfield, Nancy J. Ganson, Angelo Moreno

المصدر: Cell chemical biology, vol 26, iss 5
Cell Chem Biol

مصطلحات موضوعية: Clinical Biochemistry, Oligonucleotides, Pharmacology, Inbred C57BL, Aptamers, Ferric Compounds, 01 natural sciences, Biochemistry, Polyethylene Glycols, Antigen-Antibody Reactions, Mice, Drug Discovery, anti-PEG antibodies, Immunogenicity, PEGylation, aPTT, aptamer, Aptamers, Nucleotide, 5.1 Pharmaceuticals, Molecular Medicine, ELISA, Female, Partial Thromboplastin Time, hypersensitivity, Development of treatments and therapeutic interventions, Antibody, Nucleotide, Biotechnology, Single administration, REGULATE-PCI, Aptamer, macromolecular substances, Biology, RB006, Anticoagulant activity, Article, Antibodies, Factor IXa, Chlorides, Pharmacokinetics, PEG ratio, Animals, Humans, Molecular Biology, rhesus monkeys, Animal, 010405 organic chemistry, technology, industry, and agriculture, Anticoagulants, Thrombosis, PEG, Macaca mulatta, 0104 chemical sciences, Mice, Inbred C57BL, Disease Models, Animal, Disease Models, biology.protein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef375a25cdd6793ec2e815a62e8cf9c
https://doi.org/10.1016/j.chembiol.2019.02.001

المؤلفون: Bruce A. Sullenger, Juliana M. Layzer, David Boczkowski, Claudia M. Dollins, Jaewoo Lee, Eli Gilboa, Smita K. Nair

المصدر: Chemistry & Biology. 15(7):675-682

مصطلحات موضوعية: Agonist, Scaffold, medicine.drug_class, Aptamer, Chemistry, Pharmaceutical, Cell, Clinical Biochemistry, Biology, Ligands, Cancer Vaccines, Biochemistry, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Drug Discovery, medicine, Animals, Technology, Pharmaceutical, Receptor, Molecular Biology, 030304 developmental biology, Pharmacology, 0303 health sciences, Cell growth, NF-kappa B, RNA, General Medicine, Dendritic Cells, Receptors, OX40, Molecular biology, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, CHEMBIO, 030220 oncology & carcinogenesis, Drug Design, Molecular Medicine, Female, Nuclear localization sequence, Aptamers, Peptide, Neoplasm Transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce224aa1d05ef3000be38efeb776778

المؤلفون: Paloma H. Giangrande, Eran R. Andrechek, Walter J. Koch, JianXin Zhang, Juliana M. Layzer, Joseph R. Nevins, Andrea D. Eckhart, Alice K. Tanner, Janelle R. Keys, Bruce A. Sullenger, Rachel E. Rempel, Per Otto Hagen

المصدر: Proceedings of the National Academy of Sciences. 104:12988-12993

مصطلحات موضوعية: medicine.medical_specialty, Vascular smooth muscle, Intimal hyperplasia, Vena Cava, Inferior, Biology, Cell fate determination, Muscle, Smooth, Vascular, Mice, Internal medicine, medicine, Animals, RNA, Small Interfering, E2F, E2F4, Cells, Cultured, Cell Proliferation, Hyperplasia, Multidisciplinary, Cell growth, Aptamers, Nucleotide, Biological Sciences, Cell cycle, medicine.disease, E2F Transcription Factors, Endocrinology, Cancer research, Tunica Intima

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc46d7f7c3a2f81b6cae22255dbaa7
https://doi.org/10.1073/pnas.0704754104

المؤلفون: Bruce A. Sullenger, Juliana M. Layzer, George A. Pitoc, Thomas L. Ortel, Christopher P. Rusconi, Dougald M. Monroe, Elizabeth Scardino

المصدر: Nature. 419:90-94

مصطلحات موضوعية: medicine.drug_class, Aptamer, Antidotes, Molecular Sequence Data, Drug action, Pharmacology, Binding, Competitive, Factor IXa, chemistry.chemical_compound, medicine, Humans, Aptamer Technology, Factor VIIIa, Oligoribonucleotides, Multidisciplinary, Base Sequence, Heparin, business.industry, Contraindications, Factor X, Anticoagulant, Anticoagulants, Thrombocytopenia, chemistry, Drug Design, Prothrombin Time, Nucleic Acid Conformation, RNA, Partial Thromboplastin Time, Anticoagulant Agent, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f04b7627f12f040a6138f05f1790cf
https://doi.org/10.1038/nature00963

المؤلفون: Y. Xu, Martin L. Ogletree, Juliana M. Layzer, Bruce A. Sullenger, W. Wu, Rebecca S. Woodruff

المصدر: Journal of thrombosis and haemostasis : JTH. 11(7)

مصطلحات موضوعية: Factor XIIa, Aptamer, Fibrin, Article, Thrombin, medicine, Humans, Blood Coagulation, Blood coagulation test, Factor XII, biology, Dose-Response Relationship, Drug, Chemistry, SELEX Aptamer Technique, Anticoagulants, Hematology, Kallikrein, Aptamers, Nucleotide, Cell biology, Kinetics, Coagulation, Biochemistry, biology.protein, Blood Coagulation Tests, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8584d62a724a97c0e2f7a562100817a6
https://pubmed.ncbi.nlm.nih.gov/23692437

المؤلفون: Juliana M. Layzer, Rinku Majumder, William E. Plautz, Bruce A. Sullenger

المصدر: Blood. 128:4946-4946

مصطلحات موضوعية: Gla domain, Factor X, Aptamer, Immunology, Allosteric regulation, Cell Biology, Hematology, Biochemistry, chemistry.chemical_compound, Thrombin, chemistry, Coagulation, medicine, Systematic evolution of ligands by exponential enrichment, medicine.drug, Factor IX

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::85ae46e034212a60e13e78611de0cec5
https://doi.org/10.1182/blood.v128.22.4946.4946

المؤلفون: Genmin Lu, Sriram Krishnaswamy, Sai K. Buddai, Juliana M. Layzer, Christopher P. Rusconi, Dougald M. Monroe, Bruce A. Sullenger

مصطلحات موضوعية: Enzyme complex, medicine.drug_mechanism_of_action, Aptamer, Factor Xa Inhibitor, Biochemistry, chemistry.chemical_compound, Thrombin, Prothrombinase, Zymogen, medicine, Humans, Molecular Biology, biology, Chemistry, Factor X, Factor V, Anticoagulants, Cell Biology, Aptamers, Nucleotide, Factor Xa, biology.protein, Enzymology, Calcium, medicine.drug, Factor Xa Inhibitors, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b921d57aa48a5dac5966a16d82ecc1ed

المؤلفون: Juliana M. Layzer, Nanette L.S. Que-Gewirth, Shahid M Nimjee, Bruce A. Sullenger, Sabah Oney, David Ginsburg, Gowthami M. Arepally, Richard C. Becker

المصدر: Oligonucleotides. 17(3)

مصطلحات موضوعية: Blood Platelets, Platelet Aggregation, Platelet Function Tests, medicine.medical_treatment, Aptamer, Oligonucleotides, Pharmacology, Biology, Von Willebrand factor, von Willebrand Factor, Genetics, medicine, Humans, Platelet, Thrombus, Antidote, Molecular Biology, Vascular disease, SELEX Aptamer Technique, food and beverages, Thrombosis, Aptamers, Nucleotide, medicine.disease, Ristocetin, Immunology, biology.protein, Molecular Medicine, Platelet Aggregation Inhibitors, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5235919ab8dd91c856429510de619e61
https://pubmed.ncbi.nlm.nih.gov/17854267

المؤلفون: Juliana M. Layzer, Bruce A. Sullenger

المصدر: Oligonucleotides. 17(1)

مصطلحات موضوعية: Pyrimidine, Proteome, Aptamer, Biology, chemistry.chemical_compound, Matrix gla protein, Genetics, medicine, Humans, Molecular Biology, Factor IX, Factor VII, SELEX Aptamer Technique, Proteins, Aptamers, Nucleotide, Molecular biology, In vitro, Blood Coagulation Factors, Pyrimidines, chemistry, Biochemistry, Purines, biology.protein, Molecular Medicine, Prothrombin, 1-Carboxyglutamic Acid, Systematic evolution of ligands by exponential enrichment, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb523697259b22781402649859a2509
https://pubmed.ncbi.nlm.nih.gov/17461758

المؤلفون: Mark A. Kay, Bruce A. Sullenger, Anton P. McCaffrey, Juliana M. Layzer, Zan Huang, Alice K. Tanner

مصطلحات موضوعية: Nuclease, Small interfering RNA, biology, Trans-acting siRNA, RNA, Transfection, Endonucleases, In vitro, Mice, Biochemistry, In vivo, Report, Gene expression, Luminescent Measurements, biology.protein, Animals, RNA, Small Interfering, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f04193fcac072e99876e577770f1a9
https://europepmc.org/articles/PMC1370566/

المؤلفون: Juliana M. Layzer, Anton P. Mccaffrey, Alice K. Tanner, Zan Huang, Mark A. Kay, Bruce A. Sullenger

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://kaylab.stanford.edu/manuscripts/RNA-04-layzer.pdf.

مصطلحات موضوعية: RNAi, siRNA, modified nucleotides, luciferase

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.419.1361; http://kaylab.stanford.edu/manuscripts/RNA-04-layzer.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.419.1361
http://kaylab.stanford.edu/manuscripts/RNA-04-layzer.pdf

المؤلفون: Joseph R. Nevins, Paloma H. Giangrande, Juliana M. Layzer, JianXin Zhang, Otto Hagen, Bruce A. Sullenger

المصدر: Molecular Therapy. 11:S146-S147

مصطلحات موضوعية: Pharmacology, Tunica media, Pathology, medicine.medical_specialty, Intimal hyperplasia, Vascular smooth muscle, business.industry, medicine.medical_treatment, Ischemia, Anatomy, medicine.disease, Tunica intima, Stenosis, medicine.anatomical_structure, Restenosis, Angioplasty, Drug Discovery, Genetics, medicine, Molecular Medicine, business, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::583a8215a70585633f33c19b8ccfa53d
https://doi.org/10.1016/j.ymthe.2005.06.380