المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/journal_contribution/Primers_used_to_make_mutant_HSV-1_strains_by_two-step_Red_recombination_/15174895

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s007

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/journal_contribution/SAXS_data_collection_and_analysis_parameters_/15174892

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s006

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Whole_genome_sequencing_of_wild-type_and_mutant_HSV-1_/15174886

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s004

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Adaptation_of_viruses_encoding_pUL21_PP1-binding_mutants_to_culture_in_Vero_cells_/15174883

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s003

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Potential_RVxF_motifs_of_pUL21_/15174877

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s001

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/dataset/Identification_of_putative_pUL21_cellular_interaction_partners_by_quantitative_mass_spectrometry_/15174898

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s008

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Purification_of_hyperphosphorylated_CERT_/15174880

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.s002

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/HSV-1_pUL21_directly_binds_host_proteins_CERT_and_PP1_promoting_CERT_dephosphorylation_/15174901

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g001

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/The_C-terminal_domain_of_pUL21_binds_CERT_whereas_the_N-terminal_domain_and_disordered_linker_bind_PP1_/15174904

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g002

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/pUL21_recruits_PP1_via_a_conserved_motif_in_the_linker_region_to_accelerate_CERT_dephosphorylation_/15174907

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g003

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Mutant_HSV-1_where_PP1_binding_of_pUL21_is_abolished_adapts_rapidly_to_cell_culture_via_compensatory_mutations_in_the_kinase_gene_US3_/15174910

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g004

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/Abolition_of_pUL21_PP1_binding_severely_restricts_HSV-1_replication_and_spread_/15174913

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g005

المؤلفون: Tomasz H. Benedyk (11278840), Julia Muenzner (1894084), Viv Connor (3175485), Yue Han (560788), Katherine Brown (3554930), Kaveesha J. Wijesinghe (11278843), Yunhui Zhuang (11242950), Susanna Colaco (41652), Guido A. Stoll (11278846), Owen S. Tutt (11278849), Stanislava Svobodova (11278852), Dmitri I. Svergun (25365), Neil A. Bryant (11278855), Janet E. Deane (3287961), Andrew E. Firth (10325575), Cy M. Jeffries (9173851), Colin M. Crump (7129754), Stephen C. Graham (9904198)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Evolutionary Biology, Ecology, Science Policy, Mental Health, Infectious Diseases, Plant Biology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, pUL 21 antagonises, pUS 3 activity, herpes simplex virus replication, herpes simplex virus, virus replication, pUL 21, spread, HSV, protein phosphatase 1, PP 1 recruitment, virus-directed phosphatase activity, pUL 21 PP 1-binding

Relation: https://figshare.com/articles/figure/pUL21_antagonises_pUS3-mediated_protein_phosphorylation_and_NEC_distribution_/15174916

الاتاحة: https://doi.org/10.1371/journal.ppat.1009824.g006