المؤلفون: Naoya Kitamura (4340512), Michael Dominic Sacco (10693136), Chunlong Ma (278995), Yanmei Hu (481598), Julia Alma Townsend (10693139), Xiangzhi Meng (310468), Fushun Zhang (158697), Xiujun Zhang (390551), Mandy Ba (10693142), Tommy Szeto (10213100), Adis Kukuljac (10693145), Michael Thomas Marty (10693148), David Schultz (1753279), Sara Cherry (170695), Yan Xiang (50965), Yu Chen (29959), Jun Wang (5906)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, novel binding pocket, one-pot Ugi four-component reaction, structure-based drug design, GC 376, 23 R, S 4 pockets, noncovalent SARS-CoV -2 M, 8-76-3A, XII, SARS-CoV -2 M, inhibitor GC 376, calpain inhibitors II

Relation: https://figshare.com/articles/journal_contribution/Expedited_Approach_toward_the_Rational_Design_of_Noncovalent_SARS-CoV_2_Main_Protease_Inhibitors/14478119

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00509.s001

المؤلفون: Naoya Kitamura (4340512), Michael Dominic Sacco (10693136), Chunlong Ma (278995), Yanmei Hu (481598), Julia Alma Townsend (10693139), Xiangzhi Meng (310468), Fushun Zhang (158697), Xiujun Zhang (390551), Mandy Ba (10693142), Tommy Szeto (10213100), Adis Kukuljac (10693145), Michael Thomas Marty (10693148), David Schultz (1753279), Sara Cherry (170695), Yan Xiang (50965), Yu Chen (29959), Jun Wang (5906)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, novel binding pocket, one-pot Ugi four-component reaction, structure-based drug design, GC 376, 23 R, S 4 pockets, noncovalent SARS-CoV -2 M, 8-76-3A, XII, SARS-CoV -2 M, inhibitor GC 376, calpain inhibitors II

Relation: https://figshare.com/articles/dataset/Expedited_Approach_toward_the_Rational_Design_of_Noncovalent_SARS-CoV_2_Main_Protease_Inhibitors/14478122

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00509.s002

المؤلفون: Chunlong Ma (278995), Michael Dominic Sacco (10693136), Zilei Xia (1447603), George Lambrinidis (148996), Julia Alma Townsend (10693139), Yanmei Hu (481598), Xiangzhi Meng (310468), Tommy Szeto (10213100), Mandy Ba (10693142), Xiujun Zhang (390551), Maura Gongora (10994951), Fushun Zhang (158697), Michael Thomas Marty (10693148), Yan Xiang (50965), Antonios Kolocouris (1322580), Yu Chen (29959), Jun Wang (5906)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, cell-based FlipGFP assay, SARS-CoV -2, GRL 0617, BL 2 loop, fluorescence resonance energy trans., Jun 9-75-4, Jun 9-72-2, PL, X-ray crystal structure, FlipGFP-Based Reporter Assay, Molecular dynamics simulations, SARS-CoV -2 antivirals, BSL -2, inhibitor

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_SARS-CoV_2_Papain-like_Protease_Inhibitors_through_a_Combination_of_High-Throughput_Screening_and_a_FlipGFP-Based_Reporter_Assay/14810492

الاتاحة: https://doi.org/10.1021/acscentsci.1c00519.s001