المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/journal_contribution/Raw_western_blot_images_/15024723

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s011

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/figure/Additional_file_1_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714281

الاتاحة: https://doi.org/10.6084/m9.figshare.16714281.v1

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/figure/Additional_file_2_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714284

الاتاحة: https://doi.org/10.6084/m9.figshare.16714284.v1

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/figure/Additional_file_3_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714287

الاتاحة: https://doi.org/10.6084/m9.figshare.16714287.v1

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/dataset/Additional_file_7_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714296

الاتاحة: https://doi.org/10.6084/m9.figshare.16714296.v1

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/dataset/Additional_file_5_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714290

الاتاحة: https://doi.org/10.6084/m9.figshare.16714290.v1

المؤلفون: Anika V. Prabhu (11509623), Insung Kang (608313), Raffaella De Pace (5147120), Christopher A. Wassif (11509626), Hideji Fujiwara (644110), Pamela Kell (11509629), Xuntian Jiang (2031358), Daniel S. Ory (260307), Juan S. Bonifacino (7257743), Michael E. Ward (9653039), Forbes D. Porter (125687)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Human induced pluripotent stem cells, Human neurons, Niemann-Pick disease, type C1, Neurodegeneration, NPC1, Lysosomal disease

Relation: https://figshare.com/articles/figure/Additional_file_6_of_A_human_iPSC-derived_inducible_neuronal_model_of_Niemann-Pick_disease_type_C1/16714293

الاتاحة: https://doi.org/10.6084/m9.figshare.16714293.v1

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/_-Syn_fibrils_are_transferred_from_donor_to_acceptor_cells_inside_of_lysosomes_through_TNTs_/15024693

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s002

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/Lysosome_positioning_affects_the_efficiency_of_-syn_fibrils_transfer_in_HeLa_cells_/15024708

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s006

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/Validation_of_CAD-HeLa_coculture_system_with_additional_information_/15024711

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s007

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/EM_images_of_control_CAD_cells_/15024690

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s001

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/media/Monitoring_of_CAD_cells_overexpressing_soluble_-syn-GFP_up_to_4_hours_/15024717

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s009

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/Time_frames_of_S1_and_S2_Movies_of_CAD_cells_overexpressing_soluble_-syn-GFP_treated_or_not_with_Alexa_568_tagged_-syn_fibrils_up_to_4_hours_/15024702

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s005

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/_-Syn_fibrils_do_not_induce_lysophagy_/15024699

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s004

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/Schematic_presentation_of_experimental_designs_/15024696

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s003

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/dataset/Numerical_raw_data_/15024720

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s010

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/Lysosome_positioning_affects_the_efficiency_of_-syn_fibrils_transfer_/15024744

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.g007

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/_-Syn_fibrils_affect_the_function_of_lysosomes_/15024729

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.g002

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/media/Seeding_of_-syn-GFP_aggregates_in_CAD_cells_overexpressing_soluble_-syn-GFP_treated_with_-syn_fibrils_up_to_4_hours_/15024714

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.s008

المؤلفون: Aysegul Dilsizoglu Senol (11160729), Maura Samarani (11160732), Sylvie Syan (211304), Carlos M. Guardia (4379614), Takashi Nonaka (76323), Nalan Liv (284305), Patricia Latour-Lambert (411010), Masato Hasegawa (144940), Judith Klumperman (20009), Juan S. Bonifacino (7257743), Chiara Zurzolo (263796)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, lysosome, fibril, acceptor cells, lysosomal membrane permeabilization, tunneling nanotubes, PD, EM, TFEB, transfer, heterotypic coculture system, LMP, SR, TNT, syn, transcription factor EB

Relation: https://figshare.com/articles/figure/_-Syn_fibrils_induce_LMP_upon_arrival_in_the_acceptor_cells_/15024747

الاتاحة: https://doi.org/10.1371/journal.pbio.3001287.g008