المؤلفون: Nataliia Petruk, Arafat Siddiqui, Sina Tadayon, Jorma Määttä, Pieta K. Mattila, Arja Jukkola, Jouko Sandholm, Katri S. Selander

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: CD73, TNBC, zoledronate, tumor growth, tumor-infiltrating lymphocytes, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179022/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/c691c9662b4e4c29ad3dfd77fdd5528d

المؤلفون: Nataliia Petruk, Sanni Tuominen, Malin Åkerfelt, Jesse Mattsson, Jouko Sandholm, Matthias Nees, Gennady G. Yegutkin, Arja Jukkola, Johanna Tuomela, Katri S. Selander

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/b2c631e7001b40c2910848b8522fac2a

المؤلفون: Arafat Siddiqui, Manuela Tumiati, Alia Joko, Jouko Sandholm, Pia Roering, Sofia Aakko, Reetta Vainionpää, Katja Kaipio, Kaisa Huhtinen, Liisa Kauppi, Johanna Tuomela, Sakari Hietanen

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: DNA repair, cell cycle arrest, c-Abl, imatinib, mitoxantrone, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.733700/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/6a72803515b2449c90dd67582d36c593

المؤلفون: Kirsi Savijoki, Tuula A. Nyman, Veera Kainulainen, Ilkka Miettinen, Pia Siljamäki, Adyary Fallarero, Jouko Sandholm, Reetta Satokari, Pekka Varmanen

المصدر: Frontiers in Microbiology, Vol 10 (2019)

مصطلحات موضوعية: Lactobacillus rhamnosus, probiotic, biofilm, surface protein, fructose, mucus, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.01272/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/97bcac8ca6524187b9453786b3df8f95

المؤلفون: Katriina Peltola, Maija Hollmen, Sanna-Mari Maula, Eeva Rainio, Raija Ristamäki, Marjaana Luukkaa, Jouko Sandholm, Maria Sundvall, Klaus Elenius, Päivi J. Koskinen, Reidar Grenman, Sirpa Jalkanen

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 7, Pp 629-636 (2009)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558609800158; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

URL الوصول: https://doaj.org/article/f39f0703391348d1b7ab961cee659c25

المؤلفون: Kemal Alpay, Mehdi Farshchian, Johanna Tuomela, Jouko Sandholm, Kaappo Aittokallio, Elina Siljamäki, Marko Kallio, Veli-Matti Kähäri, Sakari Hietanen

المصدر: PLoS ONE, Vol 9, Iss 8, p e105526 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4141754?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/00bce11addea4cc6b760d3a7f76310d7

المؤلفون: Mirko Scortichini (4007366), Riham Mohammed Idris (12004297), Susanne Moschütz (8682114), Antje Keim (12004300), Veronica Salmaso (2609254), Clemens Dobelmann (6493580), Paola Oliva (5065214), Karolina Losenkova (6493583), Heikki Irjala (456636), Samuli Vaittinen (4233496), Jouko Sandholm (620280), Gennady G. Yegutkin (421106), Norbert Sträter (1550494), Anna Junker (1950910), Christa E. Müller (1550497), Kenneth A. Jacobson (117993)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Virology, Chemical Sciences not elsewhere classified, predicted conformational diversity, benzyloxyimino group (<, >- amido group, 5 ′- α, blocking cd73 activity, two inhibitors indicated, human cd73 inhibitors, 3 ‑ methylcytidine, 24 , cd73 inhibitors, adenine inhibitors, p <, k <, e <, , ∼ 20, tumor tissues, subsequent conjugation, reporter moieties, recently reported

Relation: https://figshare.com/articles/journal_contribution/Structure_Activity_Relationship_of_3_Methylcytidine-5_-_-methylenediphosphates_as_CD73_Inhibitors/19074061

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01852.s001

المؤلفون: Arafat Siddiqui (11454622), Manuela Tumiati (8117963), Alia Joko (11454625), Jouko Sandholm (620280), Pia Roering (3178305), Sofia Aakko (11454628), Reetta Vainionpää (11454631), Katja Kaipio (463692), Kaisa Huhtinen (1725418), Liisa Kauppi (7595276), Johanna Tuomela (620279), Sakari Hietanen (620283)

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, DNA repair, cell cycle arrest, c-Abl, imatinib, mitoxantrone

Relation: https://figshare.com/articles/presentation/Presentation_1_Targeting_DNA_Homologous_Repair_Proficiency_With_Concomitant_Topoisomerase_II_and_c-Abl_Inhibition_zip/16643095

الاتاحة: https://doi.org/10.3389/fonc.2021.733700.s002

المؤلفون: Nataliia Petruk, Arafat Siddiqui, Sina Tadayon, Arja Jukkola, Jorma Määttä, Pieta Mattila, Jouko Sandholm, Katri S. Selander

المصدر: Cancer Research. 83:PD2-07

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d6f07c6a165ac29130f53a1e626d89b3
https://doi.org/10.1158/1538-7445.sabcs22-pd2-07

المؤلفون: Nataliia Petruk, Arafat Siddiqui, Jorma Määttä, Jouko Sandholm, Katri Selander

المصدر: Cancer Research. 82:PD3-09

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ebb647ed82876e44430697b10c099ed1
https://doi.org/10.1158/1538-7445.sabcs21-pd3-09

المؤلفون: Nataliia Petruk, Arafat Siddiqui, Sina Tadayon, Jorma Määttä, Pieta K. Mattila, Arja Jukkola, Jouko Sandholm, Katri S. Selander

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, CD73, TNBC, zoledronate, tumor growth, tumor-infiltrating lymphocytes

Relation: https://figshare.com/articles/dataset/DataSheet_1_CD73_regulates_zoledronate-induced_lymphocyte_infiltration_in_triple-negative_breast_cancer_tumors_and_lung_metastases_docx/23700951

الاتاحة: https://doi.org/10.3389/fimmu.2023.1179022.s001
https://figshare.com/articles/dataset/DataSheet_1_CD73_regulates_zoledronate-induced_lymphocyte_infiltration_in_triple-negative_breast_cancer_tumors_and_lung_metastases_docx/23700951

المؤلفون: Tove J. Grönroos, Eliisa Löyttyniemi, Johan Rajander, Thomas Keller, Dominik Eichin, Jouko Sandholm, Sanni Tuominen, Nataliia Petruk, Johanna Tuomela, Alejandra Verhassel, Francisco R. López-Picón

المصدر: European Journal of Nuclear Medicine and Molecular Imaging

مصطلحات موضوعية: 0301 basic medicine, Biodistribution, Fluorine Radioisotopes, medicine.medical_treatment, Inflammation, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Radiology, Nuclear Medicine and imaging, Tissue Distribution, Head and neck cancer, Radiotherapy, Chemistry, General Medicine, medicine.disease, Head and neck squamous-cell carcinoma, In vitro, Radiation therapy, 030104 developmental biology, PET, Pyrimidines, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Positron-Emission Tomography, [18F]F-DPA, Cancer research, Pyrazoles, Original Article, medicine.symptom, Preclinical imaging, Ex vivo, TSPO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e968edb3fe9024039e257b5d78a59da9
http://europepmc.org/articles/PMC8113193

المؤلفون: Kenneth A. Jacobson, Mirko Scortichini, Riham M. Idris, Susanne Moschütz, Antje Keim, Veronica A. Salmaso, Clemens Dobelmann, Paola A. Oliva, Karolina Losenkova, Heikki Irjala, Samuli Vaittinen, Jouko Sandholm, Gennady G. Yegutkin, Norbert Sträter, Anna Junker, Christa E. Müller

المصدر: The FASEB Journal. 36

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d1ffef5b7605e42873b5327ca2ba53d
https://doi.org/10.1096/fasebj.2022.36.s1.r3981

المؤلفون: Karolina Losenkova, Akira Takeda, Symantas Ragauskas, Marc Cerrada-Gimenez, Maria Vähätupa, Simon Kaja, Marius L. Paul, Constanze C. Schmies, Georg Rolshoven, Christa E. Müller, Jouko Sandholm, Sirpa Jalkanen, Giedrius Kalesnykas, Gennady G. Yegutkin

المصدر: Cellular and Molecular Life Sciences. 79

مصطلحات موضوعية: Male, Retinal Ganglion Cells, Pharmacology, Mice, Inbred BALB C, Adenosine, Light, Apyrase, Apoptosis, Cell Biology, Retina, Adenosine Diphosphate, Mice, Inbred C57BL, Mice, Cellular and Molecular Neuroscience, Adenosine Triphosphate, Antigens, CD, Animals, Humans, Molecular Medicine, Female, Photoreceptor Cells, Microglia, sense organs, 5'-Nucleotidase, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9e47fff3564e83ba322c099857abf2
https://doi.org/10.1007/s00018-022-04187-4

المؤلفون: Mirko Scortichini, Riham Mohammed Idris, Susanne Moschütz, Antje Keim, Veronica Salmaso, Clemens Dobelmann, Paola Oliva, Karolina Losenkova, Heikki Irjala, Samuli Vaittinen, Jouko Sandholm, Gennady G. Yegutkin, Norbert Sträter, Anna Junker, Christa E. Müller, Kenneth A. Jacobson

المصدر: J Med Chem

مصطلحات موضوعية: Adult, Male, Diphosphonates, Molecular Structure, Palatine Tonsil, Cytosine Nucleotides, Molecular Dynamics Simulation, GPI-Linked Proteins, Article, Molecular Docking Simulation, Structure-Activity Relationship, Neoplasms, Drug Discovery, Molecular Medicine, Humans, Enzyme Inhibitors, 5'-Nucleotidase, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09bf77533e645ca0044d06f97aaa505
http://hdl.handle.net/11577/3459805

المؤلفون: N Petruk, Johanna Tuomela, Jouko Sandholm, Katri S. Selander

المصدر: Cancer Research. 79:P2-06

مصطلحات موضوعية: Cancer Research, Mammary tumor, business.industry, medicine.medical_treatment, Cancer, TLR9, Bisphosphonate, medicine.disease, Breast cancer, Oncology, Cancer cell, medicine, Cancer research, Doxorubicin, business, Triple-negative breast cancer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::56b11670a7a3c7d8eed4721cdcffa938
https://doi.org/10.1158/1538-7445.sabcs18-p2-06-23

المؤلفون: Arafat Siddiqui (11454622), Manuela Tumiati (8117963), Alia Joko (11454625), Jouko Sandholm (620280), Pia Roering (3178305), Sofia Aakko (11454628), Reetta Vainionpää (11454631), Katja Kaipio (463692), Kaisa Huhtinen (1725418), Liisa Kauppi (7595276), Johanna Tuomela (620279), Sakari Hietanen (620283)

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, DNA repair, cell cycle arrest, c-Abl, imatinib, mitoxantrone

Relation: https://figshare.com/articles/dataset/DataSheet_1_Targeting_DNA_Homologous_Repair_Proficiency_With_Concomitant_Topoisomerase_II_and_c-Abl_Inhibition_pdf/16643086

الاتاحة: https://doi.org/10.3389/fonc.2021.733700.s001

المؤلفون: Diti Desai, Jaakko Lehtimäki, Tove J. Grönroos, Jouko Sandholm, Johanna Tuomela, Jixi Zhang, Jessica M. Rosenholm

المصدر: Molecular Pharmaceutics. 14:3218-3227

مصطلحات موضوعية: medicine.medical_treatment, ta221, Lipid Bilayers, Mice, Nude, Pharmaceutical Science, 02 engineering and technology, Pharmacology, ta3111, Zoledronic Acid, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Viability assay, ta216, Lipid bilayer, ta215, Diphosphonates, Chemistry, ta1182, Imidazoles, Mesoporous silica, Bisphosphonate, ta3122, Flow Cytometry, Silicon Dioxide, 021001 nanoscience & nanotechnology, Immunohistochemistry, In vitro, Zoledronic acid, 030220 oncology & carcinogenesis, Nanoparticles, Molecular Medicine, Nanocarriers, 0210 nano-technology, Porosity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed72145ab1427b28b139eb2017ab4761
https://doi.org/10.1021/acs.molpharmaceut.7b00519

المؤلفون: Kirsi Savijoki, Tuula A. Nyman, Veera Kainulainen, Ilkka Miettinen, Pia Siljamäki, Adyary Fallarero, Jouko Sandholm, Reetta Satokari, Pekka Varmanen

المساهمون: Division of Pharmaceutical Biosciences, Molecular Dairy Microbiology, Department of Food and Nutrition, HUMI - Human Microbiome Research, Faculty of Medicine, Medicum, Pharmaceutical Design and Discovery group, Faculty of Pharmacy, Drug Research Program, Reetta Maria Satokari / Principal Investigator, Food Sciences

المصدر: Frontiers in Microbiology
Frontiers in Microbiology, Vol 10 (2019)

مصطلحات موضوعية: Microbiology (medical), EXPRESSION, Protein moonlighting, lcsh:QR1-502, ADHESIVE MOONLIGHTING PROTEINS, Microbiology, Aminopeptidase, lcsh:Microbiology, biofilm, Pilus, BACILLUS-SUBTILIS, fructose, 03 medical and health sciences, chemistry.chemical_compound, Lactobacillus rhamnosus, mucus, REVEALS, EXTRACELLULAR-MATRIX, PROBIOTIC LACTOBACILLI, 1183 Plant biology, microbiology, virology, Original Research, 030304 developmental biology, surface protein, 0303 health sciences, FUNCTIONAL-ANALYSIS, biology, 030306 microbiology, Chemistry, BIOFILM FORMATION, Biofilm, Fructose, biology.organism_classification, Mucus, Bacterial adhesin, adhesion, Biochemistry, 317 Pharmacy, PROTEOMICS, probiotic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0d5836d3c3a3dfeb86b097b65317f8
https://doi.org/10.1101/579953

المؤلفون: Kevin W. Harris, Jeremy Clark, Jouko Sandholm, Aleksi Schrey, Arja Jukkola-Vuorinen, Jaakko Lehtimäki, Pirkko Härkönen, Katri S. Selander, Johanna Tuomela, Sadanandan E. Velu, Tamiko Ishizu

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Pathology, bisphosphonate, medicine.medical_treatment, ApppI, Breast Neoplasms, ta3111, p38 Mitogen-Activated Protein Kinases, 03 medical and health sciences, TLR9, Mice, 0302 clinical medicine, Breast cancer, breast cancer, Internal medicine, ABO blood group system, Cell Line, Tumor, medicine, Animals, Humans, RNA, Small Interfering, Veterans Affairs, Cell Proliferation, Diphosphonates, business.industry, Cancer, rap1 GTP-Binding Proteins, Bisphosphonate, medicine.disease, ta3122, 030104 developmental biology, Otorhinolaryngology, 030220 oncology & carcinogenesis, Toll-Like Receptor 9, Biomarker (medicine), biomarker, Female, business, Adjuvant, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bb071587aaa492569f53f630360fd1
http://europepmc.org/articles/PMC5349995