المؤلفون: Nour Ghaddar, Shuo Wang, Bethany Woodvine, Jothilatha Krishnamoorthy, Vincent van Hoef, Cedric Darini, Urszula Kazimierczak, Nicolas Ah-son, Helmuth Popper, Myriam Johnson, Leah Officer, Ana Teodósio, Massimo Broggini, Koren K. Mann, Maria Hatzoglou, Ivan Topisirovic, Ola Larsson, John Le Quesne, Antonis E. Koromilas

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c5184c726c2a4e1fa460c06a009a5df9

المؤلفون: Cedric Darini, Nour Ghaddar, Catherine Chabot, Gloria Assaker, Siham Sabri, Shuo Wang, Jothilatha Krishnamoorthy, Marguerite Buchanan, Adriana Aguilar-Mahecha, Bassam Abdulkarim, Jean Deschenes, Jose Torres, Josie Ursini-Siegel, Mark Basik, Antonis E. Koromilas

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/7ecf6c59b1264893ab9910b75de10e72

المؤلفون: Antonis E. Koromilas, Maria Hatzoglou, Shuo Wang, Arnold S. Kristof, Kirk A. Staschke, Arkady Khoutorsky, Urszula Kazimierczak, Zineb Mounir, Jothilatha Krishnamoorthy, Clara Tenkerian

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb33ca004ce4ffe933c09aa719d2e90
https://doi.org/10.1158/1541-7786.22514965.v1

المؤلفون: Maria Hatzoglou, Cedric Darini, Nour Ghaddar, John Le Quesne, Myriam Johnson, Ola Larsson, Leah Officer, Antonis E. Koromilas, Jothilatha Krishnamoorthy, Bethany Woodvine, Shuo Wang, Koren K. Mann, Vincent van Hoef, H. Popper, Massimo Broggini, Ivan Topisirovic, Ana Teodósio, Urszula Kazimierczak, Nicolas Ah-son

المساهمون: Woodvine, Bethany [0000-0001-8359-6476], Popper, Helmuth [0000-0003-4970-1265], Officer, Leah [0000-0002-3690-2386], Teodósio, Ana [0000-0002-1386-6730], Broggini, Massimo [0000-0002-8138-9358], Hatzoglou, Maria [0000-0003-2037-1231], Topisirovic, Ivan [0000-0002-5510-9762], Larsson, Ola [0000-0003-1412-1308], Le Quesne, John [0000-0003-3552-7446], Koromilas, Antonis E [0000-0003-1972-0799], Apollo - University of Cambridge Repository, Koromilas, Antonis E. [0000-0003-1972-0799]

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Male, 82/29, Translation, Indoles, Lung Neoplasms, Carcinogenesis, Eukaryotic Initiation Factor-2, General Physics and Astronomy, Kaplan-Meier Estimate, medicine.disease_cause, 0302 clinical medicine, 42/89, 631/337/574, Medicine, Phosphorylation, eIF2, Multidisciplinary, biology, Kinase, 631/67/1612/1350, 13/31, 030220 oncology & carcinogenesis, Adenocarcinoma, 38/39, 64/60, Female, KRAS, Mitogen-Activated Protein Kinases, Science, DUSP6, Mice, Nude, 13/106, Article, General Biochemistry, Genetics and Molecular Biology, 38/91, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Dual Specificity Phosphatase 6, Stress, Physiological, Cell Line, Tumor, Integrated stress response, Animals, Humans, Lung cancer, business.industry, Adenine, General Chemistry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, 14/63, biology.protein, Cancer research, 119, 82/51, business, Non-small-cell lung cancer

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a5c15cd00a31ef21743e79af306587
https://www.repository.cam.ac.uk/handle/1810/327411

المؤلفون: Jyotsana Gupta, Shinji Kuninaka, Jothilatha Krishnamoorthy, Zhilin Deng, Antonis E. Koromilas, Kamindla Rajesh, Shuo Wang, Andreas I. Papadakis, Urszula Kazimierczak

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, mRNA translation, Eukaryotic Initiation Factor-2, translation initiation factor eIF2, Protein Serine-Threonine Kinases, Biology, medicine.disease_cause, Mice, 03 medical and health sciences, large tumor suppressor 1, Cell Line, Tumor, Serine, medicine, Animals, Humans, Hippo Signaling Pathway, Protein phosphorylation, Phosphorylation, Mice, Knockout, Genetics, eIF2, Hippo signaling pathway, Cell Death, Cell growth, Activating Transcription Factor 4, protein phosphorylation, Cell biology, Oxidative Stress, 030104 developmental biology, Gene Expression Regulation, Oncology, Hippo signaling, Oxidative stress, Signal Transduction, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a554d1b1b765345896d7f2ac31ab9ca6
https://doi.org/10.18632/oncotarget.10480

المؤلفون: V. Van Hoef, Shuo Wang, Antonis E. Koromilas, Nour Ghaddar, Ivan Topisirovic, H. Popper, Jothilatha Krishnamoorthy, J. Le Quesne, Ola Larsson, Cedric Darini, B. Woodvine

المصدر: European Journal of Cancer. 138:S23

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Vulnerability, medicine.disease_cause, medicine.disease, Internal medicine, medicine, Integrated stress response, KRAS, Lung cancer, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::461486c54ad7398e4bfdf5ce9b3ea90a
https://doi.org/10.1016/s0959-8049(20)31126-6

المؤلفون: Jyotsana Gupta, Cedric Darini, Maria Hatzoglou, Shuo Wang, George Simos, Clara Tenkerian, Jothilatha Krishnamoorthy, Antonis E. Koromilas, Valentina Gandin, Kirk A. Staschke, Abhishek Ghosh, Arnold S. Kristof, Ivan Topisirovic, Nour Ghaddar

المصدر: Cell Death and Disease, Vol 9, Iss 3, Pp 1-12 (2018)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Time Factors, Eukaryotic Initiation Factor-2, Immunology, Down-Regulation, Mice, SCID, mTORC1, Mechanistic Target of Rapamycin Complex 1, medicine.disease_cause, Antioxidants, Article, Mice, eIF-2 Kinase, 03 medical and health sciences, Cellular and Molecular Neuroscience, Downregulation and upregulation, Tuberous Sclerosis, Neoplasms, Tuberous Sclerosis Complex 2 Protein, Serine, medicine, Animals, Humans, Phosphorylation, lcsh:QH573-671, Cells, Cultured, Cell Death, lcsh:Cytology, Chemistry, Endoplasmic reticulum, Cell Biology, Fibroblasts, Tumor Burden, Cell biology, Oxidative Stress, 030104 developmental biology, Tumor progression, Female, TSC2, Reactive Oxygen Species, Oxidative stress, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408829a74acb23be54886b2b0c645195
https://doi.org/10.1038/s41419-018-0326-2

المؤلفون: Antonis E. Koromilas, Zineb Mounir, Jennifer F. Raven, Jothilatha Krishnamoorthy

المصدر: Cell Cycle. 7:2346-2351

مصطلحات موضوعية: viruses, Eukaryotic Initiation Factor-2, Biology, Virus Replication, Antiviral Agents, environment and public health, Mice, eIF-2 Kinase, Animals, Humans, Phosphorylation, Molecular Biology, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, Mice, Knockout, Kinase, Vesiculovirus, Cell Biology, biology.organism_classification, Protein kinase R, Cell biology, Isoenzymes, enzymes and coenzymes (carbohydrates), Viral replication, Protein kinase domain, Vesicular stomatitis virus, biological phenomena, cell phenomena, and immunity, Vesicular Stomatitis, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933784e9f29fca670996b0d6c5b49e44
https://doi.org/10.4161/cc.6323

المؤلفون: Arnold S. Kristof, Urszula Kazimierczak, Clara Tenkerian, Zineb Mounir, Antonis E. Koromilas, Shuo Wang, Kirk A. Staschke, Maria Hatzoglou, Jothilatha Krishnamoorthy, Arkady Khoutorsky

المصدر: Molecular cancer research : MCR. 13(10)

مصطلحات موضوعية: Cancer Research, Fibrosarcoma, Eukaryotic Initiation Factor-2, AKT1, mTORC1, Mechanistic Target of Rapamycin Complex 2, Biology, Transfection, mTORC2, Mice, eIF-2 Kinase, Cell Line, Tumor, Serine, Animals, Humans, Phosphorylation, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, eIF2, TOR Serine-Threonine Kinases, RPTOR, Endoplasmic Reticulum Stress, Cell biology, Up-Regulation, Oncology, Multiprotein Complexes, Cancer research, Unfolded protein response, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda1b0bfea3631f0e939824c4d69a687
https://pubmed.ncbi.nlm.nih.gov/26130148

المؤلفون: Jothilatha Krishnamoorthy, Polixenia Kesoglidou, Kamindla Rajesh, Antonis E. Koromilas, Andreas I. Papadakis, Farzaneh Mirzajani

المصدر: Cell Cycle

مصطلحات موضوعية: endocrine system, Indoles, mRNA translation, Eukaryotic Initiation Factor-2, Antineoplastic Agents, translation initiation factor eIF2, Biology, Cell Line, Serine, 03 medical and health sciences, Mice, eIF-2 Kinase, 0302 clinical medicine, Report, Glucose homeostasis, Animals, Humans, Protein phosphorylation, PERK/PEK kinase, Phosphorylation, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, eIF2, Cell Death, Endoplasmic reticulum, Adenine, Cell Biology, unfolded protein response, Endoplasmic Reticulum Stress, pharmacological inhibitors, 3. Good health, Cell biology, protein phosphorylation, tumorigenesis, 030220 oncology & carcinogenesis, Unfolded protein response, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4c8dd6e941a3e3a932a7802df1ae8b
https://pubmed.ncbi.nlm.nih.gov/24401334

المؤلفون: Kamindla Rajesh, Shuo Wang, Antonis E. Koromilas, Jothilatha Krishnamoorthy, Andreas I. Papadakis, Urszula Kazimierczak, S Huang, Clara Tenkerian

المصدر: Cell Death & Disease

مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell Survival, Eukaryotic Initiation Factor-2, Immunology, mTORC1, Mechanistic Target of Rapamycin Complex 1, Protein Serine-Threonine Kinases, Biology, Models, Biological, Mice, Phosphoserine, eIF-2 Kinase, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Animals, Humans, Cell Lineage, Phosphorylation, Protein kinase B, PI3K/AKT/mTOR pathway, 030304 developmental biology, Sirolimus, 0303 health sciences, eIF2, Cell Death, Cell growth, TOR Serine-Threonine Kinases, Cell Biology, Oxidants, Activating Transcription Factor 4, 3. Good health, Cell biology, Enzyme Activation, Oxidative Stress, chemistry, Multiprotein Complexes, 030220 oncology & carcinogenesis, Cancer research, Original Article, Proto-Oncogene Proteins c-akt, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cd957301128cf199f99d4b07343c0c
https://doi.org/10.1038/cddis.2014.554

المؤلفون: Urszula Kazimierczak, Jothilatha Krishnamoorthy, Shuo Wang, Antonis E. Koromilas, Clara Tenkerian, R. Kamindla

المصدر: European Journal of Cancer. 50:148

مصطلحات موضوعية: Antitumor activity, Cancer Research, Tuberous sclerosis, Pathology, medicine.medical_specialty, Oncology, medicine, Cancer research, Phosphorylation, Mutant cell, Adaptation, Biology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ac94d8139edcaf9d15854f786b28e18f
https://doi.org/10.1016/s0959-8049(14)70578-7