المؤلفون: Jennifer R. Brown, Sunita R. Setlur, Gad Getz, Charles Lee, Josephine L. Klitgaard, Saranya Radhakrishnan, Stacey M. Fernandes, Reina Improgo, Bethany Tesar, Andrew Aw, Kevin Hoang, Wei Du, Parul Benien, Siddha N. Kasar, Haesook T. Kim, Lijian Yu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f14ba1af0279d843c81f86abbdcf719
https://doi.org/10.1158/1078-0432.22464900

المؤلفون: Caroline Holm Nørgaard, Lasse Hjort Jakobsen, Andrew J Gentles, Karen Dybkær, Tarec Christoffer El-Galaly, Julie Støve Bødker, Alexander Schmitz, Preben Johansen, Tobias Herold, Karsten Spiekermann, Jennifer R Brown, Josephine L Klitgaard, Hans Erik Johnsen, Martin Bøgsted

المصدر: PLoS ONE, Vol 13, Iss 3, p e0193249 (2018)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5841735?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/54d6f02da4e545279292e8d9f730b34d

المؤلفون: Catherine J. Wu, Arnold S. Freedman, Stacey M. Fernandes, Eric D. Jacobsen, Josephine L. Klitgaard, Matthew S. Davids, Jennifer R. Brown, Michael Xiang, Erik A. Nelson, Sarah R. Walker, Zachary T. Giaccone, Maria Nicolais, Jennifer E. Yeh, Mousumi Chaudhury, Svitlana Tyekucheva, Yasmin Kroll, David C. Fisher, Lisa N. Heppler, Jeffrey G. Supko, David A. Frank

المصدر: Am J Hematol

مصطلحات موضوعية: Adult, Male, STAT3 Transcription Factor, Chronic lymphocytic leukemia, Constitutively active, Antineoplastic Agents, Pharmacology, Stat3 inhibitor, Article, Text mining, Cell Line, Tumor, Medicine, Humans, STAT3, Aged, Aged, 80 and over, B-Lymphocytes, biology, Dose-Response Relationship, Drug, business.industry, Gene Expression Regulation, Leukemic, Gene Expression Profiling, Drug Repositioning, Hematology, Middle Aged, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Progression-Free Survival, Neoplasm Proteins, Clinical trial, Pyrimethamine, Pharmacodynamics, biology.protein, Female, Drug Screening Assays, Antitumor, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f730dddc3d8b54c3dae3b58afdd506
https://europepmc.org/articles/PMC7954938/

المؤلفون: Jennifer R. Brown, Saranya Radhakrishnan, Sunita R. Setlur, Reina Improgo, Lijian Yu, Gad Getz, Kevin Hoang, Parul Benien, Stacey M. Fernandes, Charles Lee, Josephine L. Klitgaard, Haesook T. Kim, Bethany Tesar, Siddha Kasar, Wei Du, Andrew Aw

المصدر: Clinical Cancer Research. 23:735-745

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Somatic cell, Chronic lymphocytic leukemia, Gene Dosage, Kaplan-Meier Estimate, Biology, Polymorphism, Single Nucleotide, Gene dosage, Article, 03 medical and health sciences, Germline mutation, Exome Sequencing, medicine, Humans, Saliva, Germ-Line Mutation, In Situ Hybridization, Fluorescence, Exome sequencing, Aged, Aged, 80 and over, Genetics, Chromosome Breakage, Middle Aged, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Clone Cells, Leukemia, 030104 developmental biology, Oncology, Mutation, Disease Progression, Cancer research, Female, Chromosome Deletion, Tumor Suppressor Protein p53, Chromosome breakage, DDX3X, Chromosomes, Human, Pair 17

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787d0080f31b257c889de09e56f29ae6
https://doi.org/10.1158/1078-0432.ccr-16-0594

المؤلفون: Jennifer R. Brown, Divya Chaudhary, Bethany Tesar, Haesook T. Kim, Stacey M. Fernandes, Reuma Magori-Cohen, Lijian Yu, William F. Westlin, Siddha Kasar, Kevin Hoang, Ma. Reina Improgo, Wenyan Miao, Josephine L. Klitgaard

المصدر: British Journal of Haematology.

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Microarray, Genes, Immunoglobulin Heavy Chain, Biology, medicine.disease_cause, Cohort Studies, 03 medical and health sciences, Germline mutation, hemic and lymphatic diseases, Gene expression, medicine, Humans, Molecular Targeted Therapy, Gene, Aged, Mutation, Effector, Hematology, Middle Aged, Prognosis, Leukemia, Lymphocytic, Chronic, B-Cell, Interleukin-1 Receptor-Associated Kinases, 030104 developmental biology, Myeloid Differentiation Factor 88, Cancer research, Cytokines, Female, Signal transduction, Transcriptome, IGHV@, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd6220203b80bbed67ad8303952f94b
https://doi.org/10.1111/bjh.15714

المؤلفون: Josephine L. Klitgaard, Siddha Kasar, Deepti Gadi, Donald R. Polaski, Qiyuan Li, Matthew L. Freedman, Alexander J. Federation, Christopher J. Ott, Stacey M. Fernandes, Amanda Souza, James E. Bradner, Romina E. Lenci, Jennifer R. Brown, Matthew A. Lawlor, Logan Schwartz

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Chronic lymphocytic leukemia, Biology, Article, Histones, 03 medical and health sciences, Super-enhancer, Cell Line, Tumor, hemic and lymphatic diseases, Gene expression, medicine, Animals, Humans, Enhancer, Transcription factor, Mice, Knockout, Gene Expression Regulation, Leukemic, PAX5 Transcription Factor, Proteins, Nuclear Proteins, Acetylation, Azepines, Cell Biology, Triazoles, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Lymphocytic, Chronic, B-Cell, Chromatin, Bromodomain, Cell biology, Enhancer Elements, Genetic, 030104 developmental biology, Oncology, PAX5, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75dbad923dceb29064f184d31c23aa8
https://europepmc.org/articles/PMC6298230/

المؤلفون: Sarah R. Walker, Ellen Weisberg, Shariya Terrell, David A. Frank, Michal Bar-Natan, Martha R. Addorio, Laurie B. Gashin, Josephine L. Klitgaard, Erik A. Nelson, James D. Griffin, Loredana Santo, Rosemary Barrett, Benjamin L. Ebert

المصدر: Blood. 117:3421-3429

مصطلحات موضوعية: ABL, Immunology, breakpoint cluster region, Imatinib, Cell Biology, Hematology, Biology, medicine.disease, Biochemistry, Psychotropic drug, Nilotinib, hemic and lymphatic diseases, medicine, Cancer research, neoplasms, Tyrosine kinase, Chronic myelogenous leukemia, medicine.drug, K562 cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7f0896f1c376ec77a8ef250d626f4bb1
https://doi.org/10.1182/blood-2009-11-255232

المؤلفون: Sarah R. Walker, Erik Nelson, David A. Frank, Catherine J. Wu, Stacey M. Fernandes, Svitlana Tyekucheva, Michael Xiang, Zachary T. Giaccone, Lisa N. Heppler, Maria Nicolais, Jennifer R. Brown, Jeffrey G. Supko, Josephine L. Klitgaard, Jennifer E. Yeh, Mousumi Chaudhury, Yasmin Kroll

المصدر: Blood. 132:1855-1855

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Chronic lymphocytic leukemia, Immunology, Cell Biology, Hematology, medicine.disease, Stat3 inhibitor, Biochemistry, Clinical trial, Pyrimethamine, Internal medicine, medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3cfd32c861665587bea52d9a5a41d24f
https://doi.org/10.1182/blood-2018-99-118921

المؤلفون: David A. Frank, Klaus Koefoed, Mikkel W. Pedersen, Christian H. Geisler, Josephine L. Klitgaard, Ole V. Gadeberg, Jørgen Petersen, Jesper Jurlander

المصدر: British journal of haematology. 163(2)

مصطلحات موضوعية: Adult, Cytotoxicity, Immunologic, Male, medicine.drug_class, Cell Survival, chemical and pharmacologic phenomena, Ofatumumab, Monoclonal antibody, Antibodies, Monoclonal, Humanized, CD5 Antigens, Epitope, CD19, chemistry.chemical_compound, immune system diseases, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Humans, Alemtuzumab, Aged, CD20, Antibody-dependent cell-mediated cytotoxicity, Aged, 80 and over, Chromosome Aberrations, biology, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, hemic and immune systems, Drug Synergism, Hematology, Complement System Proteins, Middle Aged, Antigens, CD20, Leukemia, Lymphocytic, Chronic, B-Cell, Complement-dependent cytotoxicity, chemistry, Immunology, biology.protein, Female, CD5

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810eaf2164c0592642d4acd23aa69b4d
https://pubmed.ncbi.nlm.nih.gov/23927424

المؤلفون: Haesook T. Kim, Lijian Yu, Jennifer R. Brown, Kevin Hoang, William F. Westlin, Stacey M. Fernandes, Bethany Tesar, Reuma Magori-Cohen, Reina Improgo, Wenyan Miao, Josephine L. Klitgaard, Divya Chaudhary

المصدر: Blood. 126:491-491

مصطلحات موضوعية: Chronic lymphocytic leukemia, ZAP70, Immunology, breakpoint cluster region, TLR9, Cell Biology, Hematology, Biology, Gene signature, medicine.disease, Biochemistry, Gene expression profiling, Germline mutation, Cancer research, medicine, IGHV@

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ff3382ea8afcc9104dec98e252a6b4de
https://doi.org/10.1182/blood.v126.23.491.491

المؤلفون: Wei Du, Charles Lee, Josephine L. Klitgaard, Lijian Yu, Parul Benien, Jennifer R. Brown, Reina Improgo, Stacey M. Fernandes, Gady Getz, Haesook T. Kim, Sunita R. Setlur, Siddha Kasar, Kevin Hoang

المصدر: Blood. 126:2907-2907

مصطلحات موضوعية: Genetics, Oncology, medicine.medical_specialty, Chronic lymphocytic leukemia, Immunology, Cytogenetics, Wild type, Cell Biology, Hematology, Biology, medicine.disease, Biochemistry, Germline mutation, Internal medicine, medicine, Allele, DDX3X, Exome sequencing, SNP array

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::702b65757ff6230ced8ffe4a1093033e
https://doi.org/10.1182/blood.v126.23.2907.2907

المؤلفون: Siddha Kasar, Jennifer R. Brown, Alexander J. Federation, Christopher J. Ott, Josephine L. Klitgaard, James E. Bradner, Stacey M. Fernandes

المصدر: Blood. 126:436-436

مصطلحات موضوعية: Transcriptionally active chromatin, Genetics, Immunology, Enhancer RNAs, Promoter, Cell Biology, Hematology, Biology, Biochemistry, Chromatin, hemic and lymphatic diseases, Enhancer, Transcription factor, ChIA-PET, Epigenomics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8192bc6721194ef69c43d0005182437a
https://doi.org/10.1182/blood.v126.23.436.436

المؤلفون: Peter S. Andersen, Vincent W. Coljee, Lone Kjaer Rasmussen, John S. Haurum, Lars S. Nielsen, Søren Bregenholt, Josephine L. Klitgaard

المصدر: Journal of immunology (Baltimore, Md. : 1950). 177(6)

مصطلحات موضوعية: Recombinant Fusion Proteins, Immunology, Molecular Sequence Data, Immunoglobulin Variable Region, Inhibitory postsynaptic potential, law.invention, Mice, Immune system, In vivo, law, Immunology and Allergy, Animals, Humans, Amino Acid Sequence, Antibodies, Blocking, Mice, Inbred BALB C, Rh-Hr Blood-Group System, biology, Chemistry, Immunogenicity, Immune Sera, Antibodies, Monoclonal, Virology, Antibodies, Anti-Idiotypic, Protein Structure, Tertiary, Mice, Inbred C57BL, Immunization, Polyclonal antibodies, Immunoglobulin G, Recombinant DNA, biology.protein, Female, Binding Sites, Antibody, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298d79b5edac80fdfa53fa966e66d464
https://pubmed.ncbi.nlm.nih.gov/16951339

المؤلفون: Kevin Hoang, Haesook T. Kim, Bethany Tesar, Josephine L. Klitgaard, Reuma Magori-Cohen, Reina Improgo, Jennifer R. Brown, Stacey M. Fernandes

المصدر: Blood. 124:1972-1972

مصطلحات موضوعية: Chemokine, Stromal cell, biology, Chronic lymphocytic leukemia, Immunology, Context (language use), Cell Biology, Hematology, medicine.disease, Biochemistry, medicine.anatomical_structure, Apoptosis, hemic and lymphatic diseases, embryonic structures, cardiovascular system, medicine, biology.protein, Cancer research, sense organs, Bone marrow, biological phenomena, cell phenomena, and immunity, IGHV@, Lymph node

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c9357e03d12d2b0b1d5e7a80a0130657
https://doi.org/10.1182/blood.v124.21.1972.1972

المؤلفون: Mikkel W. Pedersen, Josephine L. Klitgaard, Christian H. Geisler

المصدر: Cancer Research. 71:4585-4585

مصطلحات موضوعية: CD20, Antibody-dependent cell-mediated cytotoxicity, Cancer Research, biology, CD52, medicine.drug_class, business.industry, Chronic lymphocytic leukemia, medicine.disease, Monoclonal antibody, Epitope, Oncology, immune system diseases, hemic and lymphatic diseases, Immunology, medicine, biology.protein, CD5, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7dc8b2dfae1944ac9a3e2aa213808de0
https://doi.org/10.1158/1538-7445.am2011-4585