المؤلفون: Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David D Thomas, William CK Pomerantz, Tanya S Freedman, Nicholas M Levinson

المصدر: eLife, Vol 13 (2024)

مصطلحات موضوعية: BRAF, kinase inhibitor, paradoxical activation, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/95481; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/908aea3f4eb7430b8ef82e94417a536d

المؤلفون: Dongmei Chen, Keith M. Wirth, Scott Kizy, Joseph M. Muretta, Todd W. Markowski, Peter Yong, Adam Sheka, Hisham Abdelwahab, Ann V. Hertzel, Sayeed Ikramuddin, Masato Yamamoto, David A. Bernlohr

المصدر: Molecular Cancer Research. :OF1-OF13

مصطلحات موضوعية: Cancer Research, Oncology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0d105107297ecc0672dca71345be9542
https://doi.org/10.1158/1541-7786.mcr-22-0763

المؤلفون: Cristina Olivieri, Yingjie Wang, Geoffrey C Li, Manu V S, Jonggul Kim, Benjamin R Stultz, Matthew Neibergall, Fernando Porcelli, Joseph M Muretta, David DT Thomas, Jiali Gao, Donald K Blumenthal, Susan S Taylor, Gianluigi Veglia

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: recombinant dna, protein expression, isotopic labeling, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/55607; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/34c13da9463648a9980c22009c9c1bf8

المؤلفون: David A. Bernlohr, Masato Yamamoto, Sayeed Ikramuddin, Ann V. Hertzel, Hisham Abdelwahab, Adam Sheka, Peter Yong, Todd W. Markowski, Joseph M. Muretta, Scott Kizy, Keith M. Wirth, Dongmei Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38739b241c31daaf654392c0214e24c
https://doi.org/10.1158/1541-7786.23145191.v1

المؤلفون: David A. Bernlohr, Masato Yamamoto, Sayeed Ikramuddin, Ann V. Hertzel, Hisham Abdelwahab, Adam Sheka, Peter Yong, Todd W. Markowski, Joseph M. Muretta, Scott Kizy, Keith M. Wirth, Dongmei Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6c6a3952c6c8df56d6b5a302c65f81
https://doi.org/10.1158/1541-7786.c.6662486

المؤلفون: David A. Bernlohr, Masato Yamamoto, Sayeed Ikramuddin, Ann V. Hertzel, Hisham Abdelwahab, Adam Sheka, Peter Yong, Todd W. Markowski, Joseph M. Muretta, Scott Kizy, Keith M. Wirth, Dongmei Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3316839da54bdc2cb5e1dda1e41c57
https://doi.org/10.1158/1541-7786.23145185

المؤلفون: Damien M. Rasmussen, Manny M. Semonis, Joseph M. Muretta, Andrew R. Thompson, David D. Thomas, William C.K. Pomerantz, Nicholas M. Levinson

المصدر: bioRxiv

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be22b6affe409fae8cfbcfc0f229d60
https://doi.org/10.1101/2023.04.18.536450

المؤلفون: Emily F Ruff, Joseph M Muretta, Andrew R Thompson, Eric W Lake, Soreen Cyphers, Steven K Albanese, Sonya M Hanson, Julie M Behr, David D Thomas, John D Chodera, Nicholas M Levinson

المصدر: eLife, Vol 7 (2018)

مصطلحات موضوعية: protein kinase, phosphorylation, protein dynamics, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/32766; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/f6eb943b1d3d40128485f13e5dbe282f

المؤلفون: Joseph Atherton, I-Mei Yu, Alexander Cook, Joseph M Muretta, Agnel Joseph, Jennifer Major, Yannick Sourigues, Jeffrey Clause, Maya Topf, Steven S Rosenfeld, Anne Houdusse, Carolyn A Moores

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: cryo-electron microscopy, kinesins, mechanochemistry, microtubules, mitosis, ATPase, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/27793; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/d38f07913d0549e292ce64aaddf8922a

المؤلفون: Piyali Guhathakurta, Anna L. Carter, Andrew R. Thompson, Dillon Kurila, Jeffrey LaFrence, Li Zhang, Jake R. Trask, Bri Vanderheyden, Joseph M. Muretta, James M. Ervasti, David D. Thomas

المصدر: Journal of Biological Chemistry. 298:102675

مصطلحات موضوعية: Dystrophin, Muscular Dystrophy, Duchenne, Small Molecule Libraries, Protein Domains, Humans, Genetic Therapy, Cell Biology, Molecular Biology, Biochemistry, Actins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1492b3313d87227e3159520649edb94
https://doi.org/10.1016/j.jbc.2022.102675

المؤلفون: Joseph M. Muretta, Sami Chu, David D. Thomas

مصطلحات موضوعية: chemistry.chemical_classification, education.field_of_study, Förster resonance energy transfer, Chemistry, Kinetics, Myosin, Population, Biophysics, Nucleotide, State (functional analysis), education, Beta (finance), Fluorescence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7bcb78bc31177ca5dda2cb834e81c01c
https://doi.org/10.1101/2021.06.29.450383

المؤلفون: Gianluigi Veglia, Cristina Olivieri, Manu V S, Benjamin R Stultz, Fernando Porcelli, Geoffrey Li, Joseph M. Muretta, Donald K. Blumenthal, Jonggul Kim, Susan S. Taylor, Yingjie Wang, Jiali Gao, Matthew Neibergall, David D. Thomas

المصدر: eLife, Vol 9 (2020)
eLife

مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, Magnetic Resonance Spectroscopy, Binding Kinetics, Coupled Binding and Folding, Intrinsically Disordered Proteins, Protein Kinase Inhibitor, Protein kinases, Structural Biology and Molecular Biophysics, Receptors, Cytoplasmic and Nuclear, 01 natural sciences, Mice, Settore BIO/10 - Biochimica, Biology (General), Settore CHIM/02 - Chimica Fisica, Chemistry, General Neuroscience, Intracellular Signaling Peptides and Proteins, General Medicine, Protein kinase inhibitor, Markov Chains, Cell biology, recombinant dna, Medicine, Rabbits, Research Article, QH301-705.5, medicine.drug_class, Science, Protein subunit, Protein domain, Active Transport, Cell Nucleus, Karyopherins, 010402 general chemistry, Intrinsically disordered proteins, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Escherichia coli, medicine, Animals, Nuclear export signal, Protein kinase A, Protein Kinase Inhibitors, protein expression, isotopic labeling, General Immunology and Microbiology, E. coli, Cyclic AMP-Dependent Protein Kinases, 0104 chemical sciences, 030104 developmental biology, Structural biology, Ran

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fbc6a9abdbb256fc5bf2bdd6668d7a
https://doi.org/10.7554/elife.55607

المؤلفون: Jiali Gao, Yingjie Wang, Benjamin R Stultz, Susan S. Taylor, Donald K. Blumenthal, Geoffrey Li, Matthew Neibergall, David D. Thomas, Gianluigi Veglia, Joseph M. Muretta, Jonggul Kim, Cristina Olivieri, Manu V S, Fernando Porcelli

مصطلحات موضوعية: Multi state, Chemistry, medicine.drug_class, medicine, Protein kinase inhibitor, Protein kinase A, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c726818768e85e758013d1ada1ba02c1
https://doi.org/10.7554/elife.55607.sa2

المؤلفون: Sami Chu, David D. Thomas, Joseph M. Muretta

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: structure–function, Benzylamines, Accelerated Communication, cardiac muscle, SRX, super-relaxed state, Amino Acid Motifs, Population, Kinetics, HMM, heavy meromyosin, myosin, Myosins, Biochemistry, IHM, interacting-heads motif, Myosin, Fluorescence Resonance Energy Transfer, medicine, Animals, Uracil, education, Molecular Biology, education.field_of_study, Heavy meromyosin, Chemistry, Structure function, Cardiac muscle, Cell Biology, Cardiomyopathy, Hypertrophic, Enzyme structure, enzyme structure, medicine.anatomical_structure, Förster resonance energy transfer, fluorescence resonance energy transfer (FRET), Biophysics, TR-FRET, time-resolved fluorescence resonance energy transfer, Cattle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ead090cf9050707368126534b29f93c
https://doi.org/10.1016/j.jbc.2021.101157

المؤلفون: Joseph M. Muretta

المصدر: Biophysical Journal. 119:1041-1042

مصطلحات موضوعية: Focus (computing), Chemistry, Myosin, Biophysics, Data science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0d4a0176a31662d2d5d7c89b469272c6
https://doi.org/10.1016/j.bpj.2020.08.010

المؤلفون: Abir Majumdar, Gianluigi Veglia, Andrew R. Thompson, Tiffany A. Engel, Manu Veliparambil Subrahmanian, Nicholas M. Levinson, David D. Thomas, Joseph M. Muretta, David J. Burban, Damien M. Rasmussen

المصدر: Nature chemical biology

مصطلحات موضوعية: Allosteric regulation, Cell Cycle Proteins, Cyclin A, Models, Biological, Article, 03 medical and health sciences, Allosteric Regulation, Cyclin-dependent kinase, Cyclins, Proto-Oncogene Proteins, Humans, Phosphorylation, Molecular Biology, Protein Kinase Inhibitors, 030304 developmental biology, Cyclin, 0303 health sciences, Cyclin binding, biology, Chemistry, Kinase, Tumor Suppressor Proteins, 030302 biochemistry & molecular biology, Cyclin-dependent kinase 2, Cell Cycle, Cyclin-Dependent Kinase 2, Cell Biology, Cell cycle, Cyclin-Dependent Kinases, Cell biology, enzymes and coenzymes (carbohydrates), biology.protein, biological phenomena, cell phenomena, and immunity, Microtubule-Associated Proteins, Allosteric Site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718f99a0223b2986545629535aa25c49
https://pubmed.ncbi.nlm.nih.gov/33526892

المؤلفون: Abir Majumdar, Damien M. Rasmussen, Erik B. Faber, Andrew R. Thompson, David D. Thomas, Joseph M. Muretta, Emily F. Ruff, Nicholas M. Levinson, Eric W. Lake

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Amino Acid Motifs, Allosteric regulation, Aurora inhibitor, Cell Cycle Proteins, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Aurora kinase, Allosteric Regulation, Humans, Protein Interaction Domains and Motifs, Phosphorylation, Protein Kinase Inhibitors, Mitosis, conformational selectivity, Aurora Kinase A, protein kinases, Binding Sites, Aurora inhibitors, Multidisciplinary, Chemistry, Kinase, Nuclear Proteins, Biological Sciences, 3. Good health, Cell biology, Molecular Docking Simulation, Biophysics and Computational Biology, 030104 developmental biology, PNAS Plus, 030220 oncology & carcinogenesis, Physical Sciences, DFG motif, Signal transduction, Selectivity, Microtubule-Associated Proteins, Oligopeptides, Cell Division, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7e838b277600ebbd4a0d0e15f08a2e
https://doi.org/10.1073/pnas.1811158115

المؤلفون: Joseph M. Muretta, Laura K. Gunther, Wanjian Tang, Shane D. Walton, Darshan V. Trivedi, William C. Unrath, John A. Rohde, David D. Thomas, Christopher M. Yengo

المصدر: The Journal of biological chemistry. 294(5)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, ATPase, Population, Myosin Type V, Sequence Homology, Motor Activity, medicine.disease_cause, Biochemistry, Mechanotransduction, Cellular, Motor protein, 03 medical and health sciences, Adenosine Triphosphate, Protein Domains, ATP hydrolysis, Myosin, medicine, Molecular motor, Animals, Amino Acid Sequence, education, Molecular Biology, Actin, Adenosine Triphosphatases, Mutation, education.field_of_study, 030102 biochemistry & molecular biology, biology, Chemistry, Cell Biology, Adenosine Diphosphate, 030104 developmental biology, biology.protein, Biophysics, Enzymology, Chickens, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93f1ffcafc742381a4f8907e6e86759
https://pubmed.ncbi.nlm.nih.gov/30518549

المؤلفون: Joseph M. Muretta, John A. Rohde, Osha Roopnarine, David D. Thomas

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(32)

مصطلحات موضوعية: 0301 basic medicine, Benzylamines, ATPase, Allosteric regulation, Kinetics, macromolecular substances, 03 medical and health sciences, 0302 clinical medicine, Adenosine Triphosphate, Allosteric Regulation, Myosin, medicine, Cardiomyopathy, Hypertrophic, Familial, Humans, Uracil, Actin, Multidisciplinary, biology, Chemistry, Protein Stability, Hypertrophic cardiomyopathy, Myosin Subfragments, Cardiac myosin, medicine.disease, Actins, Adenosine Diphosphate, 030104 developmental biology, PNAS Plus, biology.protein, Molecular mechanism, Biophysics, cardiovascular system, Cardiac Myosins, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f3c225fda35ed5d5f1966984e054a7
https://pubmed.ncbi.nlm.nih.gov/30018063

المؤلفون: David D. Thomas, Joseph M. Muretta, John A. Rohde

مصطلحات موضوعية: 0303 health sciences, biology, Chemistry, ATPase, Kinetics, Allosteric regulation, Hypertrophic cardiomyopathy, Cardiac myosin, macromolecular substances, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Myosin, Molecular mechanism, biology.protein, Biophysics, medicine, 030217 neurology & neurosurgery, Actin, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eece4f58b8503a3b6420d3a5f9d590e0