المؤلفون: Nianhang Chen, Nastya Kassir, Abderrahmane Laadem, Stephen E. Maxwell, Priya Sriraman, Ana Carolina Giuseppi, Steve Ritland, Peter G. Linde, Balasubrahmanyam Budda, Joseph G. Reynolds, Simon Zhou, Maria Palmisano

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 7, Pp 395-404 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/b71c1d3971b14218bd2a4fcb5ebcb47a

المؤلفون: Simon Zhou, Priya Sriraman, Ana Carolina Giuseppi, Stephen E. Maxwell, Balasubrahmanyam Budda, Peter G. Linde, Steve Ritland, Maria Palmisano, Joseph G. Reynolds, Nianhang Chen, Abderrahmane Laadem, Nastya Kassir

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 7, Pp 395-404 (2020)
CPT: Pharmacometrics & Systems Pharmacology

مصطلحات موضوعية: Adult, Male, Time Factors, Anemia, Activin Receptors, Type II, Recombinant Fusion Proteins, Population, Physiology, Article, Pharmacokinetics, Humans, Medicine, Pharmacology (medical), Dosing, Adverse effect, education, Research Articles, Aged, Aged, 80 and over, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, lcsh:RM1-950, Articles, Middle Aged, medicine.disease, Immunoglobulin Fc Fragments, Regimen, Treatment Outcome, lcsh:Therapeutics. Pharmacology, Myelodysplastic Syndromes, Modeling and Simulation, Luspatercept, Hematinics, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902d129e84b79a9e9ae185d6825800f1
https://doaj.org/article/b71c1d3971b14218bd2a4fcb5ebcb47a

المؤلفون: Balasubrahmanyam Budda, Nianhang Chen, Jeevan K. Shetty, Nastya Kassir, Ana Carolina Giuseppi, Steve Ritland, Maria Palmisano, Joseph G. Reynolds, Peter G. Linde, Priya Sriraman, Abderrahmane Laadem, Simon Zhou, Stephen E. Maxwell

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Anemia, Metabolic Clearance Rate, Thalassemia, Activin Receptors, Type II, Injections, Subcutaneous, Recombinant Fusion Proteins, 030226 pharmacology & pharmacy, Gastroenterology, 03 medical and health sciences, Hemoglobins, Young Adult, 0302 clinical medicine, Pharmacokinetics, Pharmacometrics, population pharmacokinetics, Internal medicine, medicine, Humans, Pharmacology (medical), biologics, Dosing, Adverse effect, luspatercept, Aged, Pharmacology, beta‐thalassemia, Dose-Response Relationship, Drug, business.industry, Incidence (epidemiology), Body Weight, beta-Thalassemia, Beta thalassemia, Middle Aged, medicine.disease, anemia, Immunoglobulin Fc Fragments, 030220 oncology & carcinogenesis, Area Under Curve, Hematinics, exposure‐response, Female, Hemoglobin, business, Monte Carlo Method

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bff7703dbe565b3e957a72d5febe725
http://europepmc.org/articles/PMC7754485

المؤلفون: Kathy D. Miller, István Molnár, Barry A. Siegel, Thomas Wickham, Cynthia X. Ma, Pamela N. Munster, Joseph G. Reynolds, Ian E. Krop, Patricia LoRusso, Anthony F. Shields, Bart S. Hendriks, Victor Moyo, Elena Geretti, Bambang Adiwijaya, Karen Campbell

المصدر: British Journal of Cancer
British journal of cancer, vol 119, iss 9

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunoconjugates, Receptor, ErbB-2, Gastroenterology, ErbB-2, 0302 clinical medicine, Breast cancer, Trastuzumab, Antineoplastic Combined Chemotherapy Protocols, Cancer, Brain, Hematology, Metastatic breast cancer, 3. Good health, Treatment Outcome, Oncology, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Public Health and Health Services, Female, Drug, Receptor, medicine.drug, Adult, medicine.medical_specialty, Cyclophosphamide, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Breast Neoplasms, Neutropenia, Article, Drug Administration Schedule, Dose-Response Relationship, 03 medical and health sciences, Clinical Research, Phase I trials, Internal medicine, Breast Cancer, medicine, Humans, Doxorubicin, Oncology & Carcinogenesis, Adverse effect, Survival analysis, Aged, Dose-Response Relationship, Drug, business.industry, medicine.disease, Survival Analysis, 030104 developmental biology, business, Febrile neutropenia, Single-Chain Antibodies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ed490d86acd89a47e560cfe096b3ba
http://europepmc.org/articles/PMC6219487

المؤلفون: Carolyn Barron, Xiaosha Zhang, Ulrich Germing, Karin Mayer, Markus P. Radsak, Joseph G. Reynolds, Joerg Chromik, Uwe Platzbecker, Philipp Kiewe, Abderrahmane Laadem, Kenneth M. Attie, Katharina Götze, Thomas Wolff, Aristoteles Giagounidis

المصدر: Clinical Lymphoma Myeloma and Leukemia. 20:S319-S320

مصطلحات موضوعية: myalgia, Cancer Research, medicine.medical_specialty, Erythema, business.industry, Myelodysplastic syndromes, Peripheral edema, Phases of clinical research, Hematology, medicine.disease, Lower risk, Clinical trial, Oncology, hemic and lymphatic diseases, Internal medicine, medicine, medicine.symptom, Bone pain, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0f492ac7af6c34ebe1ae882900a0b077
https://doi.org/10.1016/s2152-2650(20)30974-5

المؤلفون: Jason Gotlib, Joseph Pariseau, Jennie Zhang, Peter G. Linde, Marina Kremyanskaya, Kelly McCaul, Alessandro M. Vannucchi, Jeanne Palmer, Srdan Verstovsek, Adam J. Mead, Abderrahmane Laadem, Vincent Ribrag, Joseph G. Reynolds, Robert Peter Gale, Giovanni Barosi, Ruben A. Mesa, Claire N. Harrison, Jean-Jacques Kiladjian, Aaron T. Gerds, Torsten Gerike, Francesco Passamonti

المصدر: Blood. 134:557-557

مصطلحات موضوعية: Ruxolitinib, medicine.medical_specialty, Blood transfusion, Thrombocytosis, Anemia, business.industry, medicine.medical_treatment, Immunology, Beta thalassemia, Cell Biology, Hematology, medicine.disease, Biochemistry, Gastroenterology, Polycythemia vera, Internal medicine, medicine, medicine.symptom, Myelofibrosis, Bone pain, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c40d817eb953cf1614700e1a6cd170f3
https://doi.org/10.1182/blood-2019-122546

المؤلفون: Jennie Zhang, Wendy L. See, Pierre Fenaux, María Díez-Campelo, Peter G. Linde, Kevin Tsai, Uwe Platzbecker, Diana Ronai Dunshee, Alberto Risueño, Alan F. List, Martin Schwickart, Jianglin Ma, Rena Buckstein, Daniel Menezes, Valeria Santini, Ghulam J. Mufti, Abderrahmane Laadem, Guillermo Garcia-Manero, Rami S. Komrokji, Anita Rampersad, Mikkael A. Sekeres, Kyle J. MacBeth, Joseph G. Reynolds

المصدر: Blood. 134:2999-2999

مصطلحات موضوعية: 0301 basic medicine, Rbc transfusion, medicine.medical_specialty, Poor prognosis, business.industry, Immunology, Cell Biology, Hematology, Ring sideroblasts, Gene mutation, Patient response, Biochemistry, Frequency spectrum, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Internal medicine, medicine, In patient, Investigational therapy, business, health care economics and organizations, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::138ce9c874c21d002cb3ce63d41bade5
https://doi.org/10.1182/blood-2019-123655

المؤلفون: Bart S. Hendriks, Joseph G. Reynolds, Daniel F. Gaddy, Christopher W. Espelin, Stephan G. Klinz, Thomas Wickham

المصدر: Molecular Cancer Therapeutics. 12:1816-1828

مصطلحات موضوعية: Cancer Research, Receptor, ErbB-2, Cell, Population, Pharmacology, Mice, Drug Delivery Systems, Antigen, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Doxorubicin, Molecular Targeted Therapy, skin and connective tissue diseases, Receptor, education, education.field_of_study, Liposome, Antibiotics, Antineoplastic, Chemistry, medicine.anatomical_structure, Oncology, Cell culture, Liposomes, Drug delivery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5d63e3c1ba28d0609d04a11de86466
https://doi.org/10.1158/1535-7163.mct-13-0180

المؤلفون: Debu Tripathy, Javier Cortes, Sara A. Hurvitz, Sunil Verma, Kaveh Riahi, Kathy D. Miller, Joseph G. Reynolds, István Molnár, Thomas Wickham, Ian E. Krop, Denise A. Yardley

المصدر: BMC cancer, vol 16, iss 1
BMC Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Immunoconjugates, Receptor, ErbB-2, Polyethylene Glycols, Study Protocol, 0302 clinical medicine, ErbB-2, Trastuzumab, Antineoplastic Combined Chemotherapy Protocols, Clinical endpoint, MM­302, Molecular Targeted Therapy, Neoplasm Metastasis, skin and connective tissue diseases, Cancer, MM302, Immunotoxins, HER2-targeted liposomal doxorubicin, Metastatic breast cancer, Research Design, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Public Health and Health Services, Female, Pertuzumab, Immunoliposome, HERMIONE, medicine.drug, Receptor, medicine.medical_specialty, Anthracycline, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Breast Neoplasms, Vinorelbine, 03 medical and health sciences, Rare Diseases, Breast cancer, Clinical Research, Advanced/metastatic breast cancer, Internal medicine, Breast Cancer, Genetics, medicine, Adjuvant therapy, Humans, Oncology & Carcinogenesis, Human epidermal growth factor receptor 2/HER2/Erb2, business.industry, Evaluation of treatments and therapeutic interventions, medicine.disease, Cardiotoxicity, 030104 developmental biology, Doxorubicin, Antibody-conjugate, business, Antibody–conjugate, Single-Chain Antibodies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36066e07acaf59b1fd040bb8d35892aa
https://escholarship.org/uc/item/7b19m18n

المؤلفون: Bart S. Hendriks, Thomas Wickham, Samuel V. Agresta, Helen Lee, Elena Geretti, Clet Niyikiza, Stephan G. Klinz, Petra B. Lücker, Peter W. Zandstra, Shannon C. Leonard, Daryl C. Drummond, Joseph G. Reynolds, Ulrik B. Nielsen, Charles O. Noble, Kenneth J. Olivier

المصدر: Toxicology and Applied Pharmacology. 262:1-10

مصطلحات موضوعية: Drug, Anthracycline, Receptor, ErbB-2, media_common.quotation_subject, Induced Pluripotent Stem Cells, Mice, Nude, Breast Neoplasms, Pharmacology, Toxicology, Mice, Drug Delivery Systems, Trastuzumab, medicine, Animals, Humans, Myocytes, Cardiac, Doxorubicin, skin and connective tissue diseases, Induced pluripotent stem cell, media_common, Cardiotoxicity, Antibiotics, Antineoplastic, business.industry, Clinical trial, Female, Stem cell, business, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383e69192e693fd9989d11f09b21fab6
https://doi.org/10.1016/j.taap.2012.04.008

المؤلفون: Min Y. Cho, Joseph G. Reynolds, Hartmut Weiler, Francisco J. Naya, Chia-Ling Wu, Susan C. Kandarian, Ondra M. Kielbasa, Christine M. Snyder

المصدر: The FASEB Journal. 25:2276-2286

مصطلحات موضوعية: Scaffold protein, Immunoblotting, Phosphatase, Cobra Cardiotoxin Proteins, Muscle Proteins, Mice, Transgenic, Biology, Biochemistry, Cell Line, Research Communications, Muscle hypertrophy, Mice, Chlorocebus aethiops, Genetics, medicine, Animals, Immunoprecipitation, Regeneration, Myocyte, Muscle, Skeletal, Molecular Biology, Cells, Cultured, Costamere, Binding Sites, Calcineurin, Intracellular Signaling Peptides and Proteins, Skeletal muscle, Crotoxin, Molecular biology, Rats, Cell biology, Drug Combinations, Muscle Fibers, Slow-Twitch, medicine.anatomical_structure, Animals, Newborn, COS Cells, Carrier Proteins, C2C12, Protein Binding, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0cf3d4fea8159605eb67aaef267219
https://doi.org/10.1096/fj.10-169219

المؤلفون: Chris Rovaldi, Uwe Platzbecker, Philipp Kiewe, Matthew L. Sherman, Abderrahmane Laadem, Markus P. Radsak, Thomas Wolff, Carolyn Barron, Joseph G. Reynolds, Jörg Chromik, Peter G. Linde, Ulrich Germing, Xiaosha Zhang, Katharina Götze, Rajasekhar Nvs Suragani, Karin Mayer, Aristoteles Giagounidis, Uta Oelschlägel

المصدر: Journal of Clinical Oncology. 36:7018-7018

مصطلحات موضوعية: Cancer Research, Oncology, business.industry, Phase (matter), Myelodysplastic syndromes, Luspatercept, Cancer research, Medicine, Hemoglobin, business, Ligand (biochemistry), medicine.disease, Lower risk

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e79f199e1aece75ebd5a4a67a9f56b9
https://doi.org/10.1200/jco.2018.36.15_suppl.7018

المؤلفون: Sarah A. McCalmon, Joseph G. Reynolds, Julie A. Donaghey, Francisco J. Naya

المصدر: Journal of Biological Chemistry. 283:8070-8074

مصطلحات موضوعية: Scaffold protein, Accelerated Publications, Duchenne muscular dystrophy, Down-Regulation, Muscle Proteins, Biology, Biochemistry, Muscular Dystrophies, Cell Line, Dystrophin, Mice, Chlorocebus aethiops, medicine, Animals, Protein kinase A signaling, Muscular dystrophy, Cyclic AMP Response Element-Binding Protein, Protein kinase A, Molecular Biology, Costamere, Intracellular Signaling Peptides and Proteins, Cell Biology, medicine.disease, Cyclic AMP-Dependent Protein Kinases, Molecular biology, Hindlimb, Cell biology, Mice, Inbred mdx, biology.protein, Signal transduction, Carrier Proteins, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a951d733bb41c9623d46aef245ef8e56
https://doi.org/10.1074/jbc.c700221200

المؤلفون: James A. Richardson, Hartmut Weiler, Ondra M. Brand, Lavanya Muthukumar, Francisco J. Naya, Joseph G. Reynolds, Jennifer T. Durham, Michael Arnold

المصدر: Journal of Biological Chemistry. 281:6841-6849

مصطلحات موضوعية: Sarcomeres, Molecular Sequence Data, Muscle Proteins, Mice, Transgenic, Biology, Biochemistry, Mice, Complementary DNA, Chlorocebus aethiops, medicine, Animals, Humans, Actinin, Muscle, Skeletal, Promoter Regions, Genetic, Molecular Biology, Gene, Transcription factor, Costamere, Oligonucleotide Array Sequence Analysis, Mice, Knockout, Base Sequence, MEF2 Transcription Factors, Microarray analysis techniques, Myocardium, Intracellular Signaling Peptides and Proteins, Skeletal muscle, Cell Biology, Molecular biology, Open reading frame, medicine.anatomical_structure, Myogenic Regulatory Factors, COS Cells, Carrier Proteins, ITGA7

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb62543e50b22e037d3ab305688365dc
https://doi.org/10.1074/jbc.m510499200

المؤلفون: Kathy D. Miller, Denise A. Yardley, Joseph G. Reynolds, Debu Tripathy, Sara A. Hurvitz, Michelle Dionne, Javier Cortes, István Molnár, Ian E. Krop, Thomas Wickham, Karen Campbell, Sunil Verma

المصدر: Journal of Clinical Oncology. 34:TPS631-TPS631

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Chemotherapy, Ado-trastuzumab emtansine, Anthracycline, business.industry, medicine.medical_treatment, Locally advanced, medicine.disease, Metastatic breast cancer, Trastuzumab, Internal medicine, medicine, Pertuzumab, skin and connective tissue diseases, Previously treated, business, neoplasms, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2dce6f3bc152969b20bce0a90d59fb04
https://doi.org/10.1200/jco.2016.34.15_suppl.tps631

المؤلفون: Cynthia X. Ma, Victor Moyo, Kathy D. Miller, Patricia LoRusso, Thomas Wickham, Anthony F. Shields, István Molnár, Joseph G. Reynolds, Ty McClure, Karen Campbell, Ian E. Krop, Barry A. Siegel, Bart S. Hendriks, Pamela N. Munster

المصدر: Cancer Research. 75:CT234-CT234

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, education.field_of_study, Anthracycline, Cyclophosphamide, business.industry, Population, Neutropenia, medicine.disease, Gastroenterology, Surgery, Oncology, Trastuzumab, Internal medicine, medicine, Pertuzumab, Progression-free survival, skin and connective tissue diseases, business, education, Febrile neutropenia, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f36e7553be7c0865ca015c230fbd31a
https://doi.org/10.1158/1538-7445.am2015-ct234

المؤلفون: Kathy Miller, Javier Cortes, Sara A. Hurvitz, Ian E. Krop, Debu Tripathy, Sunil Verma, Kaveh Riahi, Joseph G. Reynolds, Thomas J. Wickham, Istvan Molnar, Denise A. Yardley

المصدر: Journal of Clinical Oncology. 33:TPS641-TPS641

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::29e03bd62e556faf93af227a978f64e3
https://doi.org/10.1200/jco.2015.33.15_suppl.tps641

المؤلفون: Thomas D. Gilmore, Joseph G. Reynolds, Daniel T. Starczynowski

المصدر: Oncogene. 24(49)

مصطلحات موضوعية: Transcriptional Activation, Cancer Research, animal structures, Mutant, Blotting, Western, Electrophoretic Mobility Shift Assay, Biology, In Vitro Techniques, medicine.disease_cause, Serine, Transactivation, Genetics, medicine, Animals, Humans, Immunoprecipitation, Phosphorylation, Luciferases, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Cells, Cultured, Sequence Deletion, Mutation, Reporter gene, Superoxide Dismutase, Tumor Necrosis Factor-alpha, Fibroblasts, Cell Transformation, Viral, Proto-Oncogene Proteins c-rel, Cell biology, embryonic structures, Cancer research, Mutagenesis, Site-Directed, REL, Chickens, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def833380f248359e011678a9c422696
https://pubmed.ncbi.nlm.nih.gov/16027730

المؤلفون: Thomas D. Gilmore, Joseph G. Reynolds, Daniel T. Starczynowski

المصدر: Oncogene. 22(44)

مصطلحات موضوعية: Transcriptional Activation, Cancer Research, animal structures, Recombinant Fusion Proteins, Mutant, Chick Embryo, Biology, chemistry.chemical_compound, Transactivation, Transcription (biology), Genetics, Animals, Humans, Amino Acid Sequence, Molecular Biology, Transcription factor, Cells, Cultured, Sequence Deletion, Cell Nucleus, NF-κB, Fibroblasts, Subcellular localization, Cell Transformation, Viral, Proto-Oncogene Proteins c-rel, Cell biology, Protein Structure, Tertiary, Retroviridae, chemistry, Cytoplasm, embryonic structures, Cancer research, Fatty Acids, Unsaturated, Mutagenesis, Site-Directed, Genes, rel, REL, Chickens, Spleen, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfef73040283c39e1543ad7f58f5b6c
https://pubmed.ncbi.nlm.nih.gov/14534540

المؤلفون: Elena Geretti, Bart S. Hendriks, Thomas Wickham, Helen Lee, Shannon C. Leonard, Stephan G. Klinz, Ulrik B. Nielsen, Joseph G. Reynolds, Daniel F. Gaddy, Christopher W. Espelin

المصدر: CPT: Pharmacometrics & Systems Pharmacology

مصطلحات موضوعية: Drug, Liposome, business.industry, Liposomal Doxorubicin, media_common.quotation_subject, Pharmacology, Pegylated Liposomal Doxorubicin, Safety profile, Pharmacokinetics, Modeling and Simulation, Drug delivery, Medicine, Original Article, Pharmacology (medical), Doxorubicin, business, media_common, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e371287fac2413a6c836ae39eb0a5d
https://doi.org/10.1038/psp.2012.16