المؤلفون: John Dunlop, Gary Stack, Menelas N. Pangalos, Joseph Coupet, Deborah L. Smith, Sharon Rosenzweig-Lipson, James E. Barrett, Hossein Mazandarani, Boyd Harrison, Jean Zhang, Siva Ramamoorthy, Lee E. Schechter, Guoming Zhang, Stephanie W. Watts, Stanley Nawoschik

المصدر: Journal of Pharmacology and Experimental Therapeutics. 337:673-680

مصطلحات موضوعية: Male, Agonist, Serotonin, medicine.medical_specialty, medicine.drug_class, Receptor expression, CHO Cells, Vabicaserin, Pharmacology, Biology, Heterocyclic Compounds, 4 or More Rings, Partial agonist, Cell Line, Rats, Sprague-Dawley, Cricetulus, Cricetinae, Internal medicine, Receptor, Serotonin, 5-HT2B, Receptor, Serotonin, 5-HT2C, medicine, Animals, Humans, Receptor, Serotonin, 5-HT2A, Molecular Targeted Therapy, Receptor, 5-HT receptor, Binding Sites, Muscle, Smooth, Recombinant Proteins, Rats, Endocrinology, Dopamine receptor, Serotonin 5-HT2 Receptor Antagonists, Molecular Medicine, Antagonism, Serotonin 5-HT2 Receptor Agonists, Antipsychotic Agents, Muscle Contraction, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be883274f8e998bcc136daf48f9bd677
https://doi.org/10.1124/jpet.111.179572

المؤلفون: Ronald C. Bernotas, Guo Ming Zhang, Lee E. Schechter, Schuyler Adam Antane, Steven Edward Lenicek, Deborah L. Smith, Boyd L. Harrison, Simon Haydar, Joseph Coupet, Albert J. Robichaud

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:6935-6938

مصطلحات موضوعية: Agonist, Tertiary amine, Pyridines, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Ligands, Biochemistry, Chemical synthesis, Sulfone, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Pyrroles, Receptor, Molecular Biology, Bicyclic molecule, Organic Chemistry, In vitro, Serotonin Receptor Agonists, chemistry, Receptors, Serotonin, 5-HT6 receptor, Molecular Medicine, Serotonin Antagonists, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa35da68335dd080eacffafc9ecca94
https://doi.org/10.1016/j.bmcl.2009.10.067

المؤلفون: William Joseph Lennox, Hossein Mazandarani, John W. Ellingboe, Deborah L. Smith, Gregory J. Tawa, Joseph Coupet, Ronald C. Bernotas, Derek C. Cole, Guoming Zhang, Lee E. Schechter, Sabrina Lombardi

المصدر: Journal of Medicinal Chemistry. 48:353-356

مصطلحات موضوعية: Indole test, Sulfonamides, Indoles, Pyrrolidines, Stereochemistry, Chemistry, Stereoisomerism, HYDIA, Structure-Activity Relationship, Receptors, Serotonin, Drug Discovery, Cyclic AMP, 5-HT6 receptor, Humans, Molecular Medicine, Selective receptor modulator, Receptor, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888e3ffa0222fc5bff9e9054f207eed1
https://doi.org/10.1021/jm049243i

المؤلفون: George Theodore Grosu, Xun Ru, Joseph Coupet, Peter S. Chan, Fuk Wah Sum, Trina Saunders, J.Donald Albright, Marvin F Reich, Xumei Du, Efren Guillermo Delos Santos, Hossein Mazandarani, John P. Dusza

المصدر: Bioorganic & Medicinal Chemistry Letters. 13:2195-2198

مصطلحات موضوعية: Vasopressin, Arginine, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Pyrrolobenzodiazepine, Carboxamide, Biochemistry, Benzazepine, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Receptor, Molecular Biology, chemistry.chemical_classification, Kidney Medulla, Dose-Response Relationship, Drug, Organic Chemistry, Benzazepines, Rats, Arginine Vasopressin, Urodynamics, Liver, nervous system, chemistry, Molecular Medicine, Indicators and Reagents, hormones, hormone substitutes, and hormone antagonists, Vasopressin Antagonists, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1d45c3c77d723f2903fa078e46bae6
https://doi.org/10.1016/s0960-894x(03)00388-3

المؤلفون: Richard Eric Mewshaw, Rulin Zhao, Terrance H. Andree, Hossein Mazandarani, Joseph Coupet, Xiaojie Shi, Julie A. Brennan, Karen L. Marquis

المصدر: Bioorganic & Medicinal Chemistry Letters. 12:271-274

مصطلحات موضوعية: Receptors, Dopamine D2, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Dopaminergic, Pharmaceutical Science, Templates, Genetic, Biochemistry, Chemical synthesis, Models, Structural, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine Agonists, Drug Discovery, Molecular Medicine, Benzopyrans, Enantiomer, Molecular Biology, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca858bb8d8f997289c34724edf5853c5
https://doi.org/10.1016/s0960-894x(01)00778-8

المؤلفون: Sharon Rosenzweig-Lipson, Hossein Mazandarani, Denise Graziano, John Dunlop, John R. Potoski, Welmaker Gregory Scott, Yingxin Zhang, Joseph Coupet, Annmarie Louise Sabb, James Albert Nelson, Michael Z. Kagan, Joan E. Sabalski, Stacey J. Sukoff

المصدر: Bioorganic & Medicinal Chemistry Letters. 10:1991-1994

مصطلحات موضوعية: Male, Agonist, Food intake, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Eating, Structure-Activity Relationship, Quinoxalines, Appetite Depressants, Drug Discovery, Receptor, Serotonin, 5-HT2C, Sprague dawley rats, medicine, Animals, Structure–activity relationship, Molecular Biology, 5-HT receptor, ED50, Chemistry, Organic Chemistry, Rats, Serotonin Receptor Agonists, Pyrazines, Receptors, Serotonin, Molecular Medicine, Serotonin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7b37b2f16fc2b0b871ffb2bfc1c2da
https://doi.org/10.1016/s0960-894x(00)00400-5

المؤلفون: George Theodore Grosu, Xun Ru, Trina Saunders, Joseph Coupet, Hossein Mazandarani, Venkatesan Aranapakam, Peter S. Chan, J.Donald Albright

المصدر: Bioorganic & Medicinal Chemistry Letters. 9:1733-1736

مصطلحات موضوعية: medicine.drug_class, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Thiophenes, Biochemistry, Chemical synthesis, Benzazepine, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Oral administration, Drug Discovery, medicine, Animals, Moiety, Pyrroles, Molecular Biology, chemistry.chemical_classification, Benzodiazepine, Organic Chemistry, Antagonist, Azepines, Benzazepines, Fibroblasts, chemistry, Benzamides, Molecular Medicine, Diuretic, Antidiuretic Hormone Receptor Antagonists, hormones, hormone substitutes, and hormone antagonists, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc179e3e61f4572874d976c946756d74
https://doi.org/10.1016/s0960-894x(99)00278-4

المؤلفون: Karen L. Marquis, Terrance H. Andree, Georgia B. McGaughey, Antoine Verwijs, James Albert Nelson, Joseph Coupet, Julie A. Brennan, Richard Eric Mewshaw, Xiaojie Shi, Hossein Mazandarani

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:2675-2680

مصطلحات موضوعية: Agonist, Indoles, Molecular model, medicine.drug_class, Stereochemistry, Dopamine Agents, Clinical Biochemistry, Pharmaceutical Science, Phenylpiperazine, Biochemistry, Chemical synthesis, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine receptor D2, Drug Discovery, medicine, Animals, Molecular Biology, Psychotropic Drugs, Bicyclic molecule, Receptors, Dopamine D2, Chemistry, Organic Chemistry, Dopaminergic, Receptors, Dopamine D3, Templates, Genetic, Ligand (biochemistry), Corpus Striatum, Rats, Kinetics, Dopamine Agonists, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b420f2b135ef4e56d46372fa4d88b4
https://doi.org/10.1016/s0960-894x(98)00474-0

المؤلفون: Michael Byron Webb, Taylor Spangler, Magid Abou-Gharbia, Karen L. Marquis, Hossein Mazandarani, Georgia B. McGaughey, Julie A. Brennan, Theodore Wasik, Joseph Coupet, Rosemary Scerni, Terrance H. Andree, Gary Paul Stack, Richard Eric Mewshaw, Xiaojie Shi

المصدر: Tetrahedron. 54:7081-7108

مصطلحات موضوعية: Agonist, Indole test, Scaffold, Intrinsic activity, medicine.drug_class, Chemistry, Stereochemistry, Organic Chemistry, Dopaminergic, Rational design, Biochemistry, Combinatorial chemistry, Drug Discovery, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52739f381a6fde91b9f3f68e9e38eff1
https://doi.org/10.1016/s0040-4020(98)00349-4

المؤلفون: G. Vice, Joseph Coupet, Peter S. Chan, A.M. Venkatesan, Jeremy Ian Levin, T. K. Bailey

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:1819-1824

مصطلحات موضوعية: Angiotensin receptor, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro, chemistry.chemical_compound, Orally active, chemistry, In vivo, Drug Discovery, Molecular Medicine, Molecular Biology, Quinazolinone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47e7ee4f23fd946fda95100e7fef8c0a
https://doi.org/10.1016/s0960-894x(01)80377-2

المؤلفون: Joseph Coupet, Carl V. Hamby, Wei Cheng, Leonard G. Meggs, Peng Li, Piero Anversa, Joseph M. Capasso, Krzysztof Reiss

المصدر: Cardiovascular Research. 28:1070-1082

مصطلحات موضوعية: Male, Alkylating Agents, medicine.medical_specialty, Adrenergic receptor, Physiology, Inositol Phosphates, Molecular Sequence Data, Clonidine, Muscle hypertrophy, Dioxanes, Rats, Sprague-Dawley, Contractility, Norepinephrine, Cytosol, Left coronary artery, Receptors, Adrenergic, alpha-1, Physiology (medical), Internal medicine, medicine.artery, medicine, Animals, Myocyte, Receptor, Inositol phosphate, Adrenergic alpha-Antagonists, Cells, Cultured, Cell Size, chemistry.chemical_classification, Base Sequence, business.industry, Myocardium, Cardiac myocyte, Constriction, Coronary Vessels, Rats, Endocrinology, chemistry, Calcium, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4008f09740a18f36ced18d0a2814431
https://doi.org/10.1093/cvr/28.7.1070

المؤلفون: Fong Lai, G. Vice, T. K. Bailey, Jeremy Ian Levin, A. Cobuzzi, L. Thibault, Joseph Coupet, A.M. Venkatesan, Peter S. Chan

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:1703-1708

مصطلحات موضوعية: Angiotensin receptor, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Angiotensin II receptor antagonist, Biochemistry, Combinatorial chemistry, Orally active, Drug Discovery, Molecular Medicine, Molecular Biology, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::02b5142af6160b9d54f3dff7e779b100
https://doi.org/10.1016/s0960-894x(00)80365-0

المؤلفون: A. Cobuzzi, Jeremy Ian Levin, G. Vice, L. Thibault, A.M. Venkatesan, Fong Lai, Peter S. Chan, T. K. Bailey, Noel Mellish, Joseph Coupet

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:1709-1714

مصطلحات موضوعية: Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Angiotensin II receptor antagonist, Pharmacology, Biochemistry, In vitro, In vivo, Drug Discovery, Molecular Medicine, Enantiomer, Molecular Biology, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f90095b7fd813a3d84997c77d6215924
https://doi.org/10.1016/s0960-894x(00)80366-2

المؤلفون: Jeremy Ian Levin, J.S. Baker, G. Vice, Joseph Coupet, Andrew S. Katocs, T. K. Bailey, F.M. Lai, Gerardo D. Francisco, Peter S. Chan, A.M. Venkatesan

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:1135-1140

مصطلحات موضوعية: Angiotensin receptor, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biological activity, Angiotensin II receptor antagonist, Biochemistry, Chemical synthesis, Orally active, Oral administration, Drug Discovery, Molecular Medicine, Molecular Biology, Short duration, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9945a8a86472a021802cfb80a94e739c
https://doi.org/10.1016/s0960-894x(01)80243-2

المؤلفون: Jeremy Ian Levin, A.M. Venkatesan, J.S. Baker, Joseph Coupet, Peter S. Chan, T. K. Bailey

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:183-188

مصطلحات موضوعية: Angiotensin receptor, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Central nervous system, Pharmaceutical Science, macromolecular substances, Biochemistry, Chemical synthesis, Angiotensin II, In vitro, medicine.anatomical_structure, Cerebral cortex, Drug Discovery, medicine, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::235cb333e19a0f0cccfcd940a4324626
https://doi.org/10.1016/s0960-894x(01)81144-6

المؤلفون: G. Vice, L. Thibault, T. K. Bailey, Fong Lai, A.M. Venkatesan, Joseph Coupet, Jeremy Ian Levin, A. Cobuzzi, Peter S. Chan, Noel Mellish

المصدر: ChemInform. 26

مصطلحات موضوعية: Chemistry, In vivo, Angiotensin II receptor antagonist, General Medicine, Enantiomer, Pharmacology, In vitro, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::315a305fed3b91ab0575f9843e1daa35
https://doi.org/10.1002/chin.199505186

المؤلفون: G. Vice, A. Cobuzzi, Joseph Coupet, Peter S. Chan, A.M. Venkatesan, Jeremy Ian Levin, Fong Lai, T. K. Bailey, L. Thibault

المصدر: ChemInform. 26

مصطلحات موضوعية: Angiotensin receptor, Orally active, Chemistry, Angiotensin II receptor antagonist, General Medicine, Pharmacology, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4900ffb6db06ffb794ed39c813a62934
https://doi.org/10.1002/chin.199505185

المؤلفون: Terrance H. Andree, Richard Eric Mewshaw, Xiaojie Shi, H. Mazandarani, A. Verwijs, Karen L. Marquis, Georgia B. McGaughey, Julie A. Brennan, James Albert Nelson, Joseph Coupet

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Dopaminergic, Phenylpiperazine, General Medicine, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9db81de2b830f6685171e8090f5d5285
https://doi.org/10.1002/chin.199908168

المؤلفون: Joseph Coupet, Xun Ru, Venkatesan Aranapakam, J.Donald Albright, George Theodore Grosu, Peter S. Chan, Trina Saunders, Hossein Mazandarani

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_classification, Benzodiazepine, Chemistry, Stereochemistry, medicine.drug_class, General Medicine, Benzazepine, chemistry.chemical_compound, Orally active, Arginine Vasopressin Receptor, medicine, Moiety, hormones, hormone substitutes, and hormone antagonists, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ab3c91b78e7a6bed7f144fa3b6cc73d4
https://doi.org/10.1002/chin.199943156

المؤلفون: Uresh Shantilal Shah, James Albert Nelson, Hossein Mazandarani, Karen L. Marquis, Joseph Coupet, Richard Eric Mewshaw, Xiaojie Shi, Julie A. Brennan, Terrance H. Andree

المصدر: ChemInform. 30

مصطلحات موضوعية: Exploit, Chemistry, Dopaminergic, General Medicine, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6110e0b7d4b9a92c6c6a9715fc5d74a9
https://doi.org/10.1002/chin.199949117