المؤلفون: Bruno Roy, Claudio Sturino, Nicolas Lachance, Robert Zamboni, Kathleen M. Metters, Christine Brideau, Lianhai Li, John Scheigetz, Danielle Denis, Deborah Slipetz, Marie-Claude Carrière, Elizabeth Cauchon, Gillian Greig, Gary P. O'Neill, Carl Berthelette, Michael J. Boyd, Marie-Claude Mathieu, Sonia Lamontagne, Nicole Sawyer, Robert N. Young, Nancy N. Tsou, Zhaoyin Wang, Stacia Kargman, Marc Labelle

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:3043-3048

مصطلحات موضوعية: Indole test, Indoles, Molecular Structure, Chemistry, Receptors, Prostaglandin, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Biochemistry, Chemical synthesis, In vitro, Structure-Activity Relationship, chemistry.chemical_compound, Safrole, Drug Discovery, Molecular Medicine, Prostaglandin D2, Receptors, Immunologic, Receptor, Molecular Biology, Prostaglandin G2, Prostaglandin D2 receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569d39021562795735b87f35c9aa72c4
https://doi.org/10.1016/j.bmcl.2006.02.062

المؤلفون: Oballa Renata Marcella, Sylvie Desmarais, Dana E. Davis, Frederic Masse, John R. Somoza, Sheldon N. Crane, Natalie Chauret, Marc Ouellet, W. Cameron Black, Greg Wesolowski, Joel Robichaud, Daniel James Mckay, Eduardo L. Setti, Christopher I. Bayly, Julie Paquet, Carmai Seto, James T. Palmer, John Scheigetz

المصدر: Journal of Medicinal Chemistry. 49:1066-1079

مصطلحات موضوعية: Male, Models, Molecular, Molecular model, Stereochemistry, medicine.drug_class, Cathepsin K, Biological Availability, Carboxamide, Crystallography, X-Ray, Chemical synthesis, Rats, Sprague-Dawley, Structure-Activity Relationship, Dogs, Cyclohexanes, Drug Discovery, medicine, Aminoacetonitrile, Animals, IC50, chemistry.chemical_classification, biology, Stereoisomerism, Amides, Cathepsins, Rats, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a4724abe55727ec51c6e5d1534ebc7
https://doi.org/10.1021/jm051059p

المؤلفون: Dwight Macdonald, Antoinette Drahus-Paone, Roy Helmy, Denis Deschenes, Guo-Jie Ho, John Scheigetz, James M. McNamara, Brenda Pipik, Yao-Jun Shi, David A. Conlon, Michel Gallant, Bruno Roy, J. Michael Williams, Anthony Mastracchio

المصدر: Organic Process Research & Development. 10:36-45

مصطلحات موضوعية: chemistry.chemical_compound, Scale (ratio), Chemistry, Process development, Organic Chemistry, Quinoline, Organic chemistry, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b0e5ea4b5cc94d87e173aec7aa586840
https://doi.org/10.1021/op050116l

المؤلفون: Dwight Macdonald, Anthony Mastracchio, Hélène Perrier, Daniel Dubé, Michel Gallant, Patrick Lacombe, Denis Deschênes, Bruno Roy, John Scheigetz, Kevin Bateman, Chun Li, Laird A. Trimble, Stephen Day, Nathalie Chauret, Deborah A. Nicoll-Griffith, Jose M. Silva, Zheng Huang, France Laliberté, Susana Liu, Diane Ethier, Doug Pon, Eric Muise, Louise Boulet, Chi Chung Chan, Angela Styhler, Stella Charleson, Joseph Mancini, Paul Masson, David Claveau, Donald Nicholson, Mervyn Turner, Robert N. Young, Yves Girard

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:5241-5246

مصطلحات موضوعية: Phosphodiesterase Inhibitors, Vomiting, Stereochemistry, Bronchoconstriction, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, Pharmacokinetics, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Saimiri, Molecular Biology, Whole blood, chemistry.chemical_classification, Sheep, biology, Organic Chemistry, In vitro, Cyclic Nucleotide Phosphodiesterases, Type 4, Rats, Enzyme, chemistry, 3',5'-Cyclic-AMP Phosphodiesterases, Enzyme inhibitor, Quinolines, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff58af67854878403c87410ee5934af1
https://doi.org/10.1016/j.bmcl.2005.08.036

المؤلفون: John Scheigetz, Robert Zamboni, Chun Li, Carl Berthelette

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 47:881-889

مصطلحات موضوعية: chemistry.chemical_classification, Carboxylic acid, Aryl, Organic Chemistry, Radiochemistry, Mass spectrometry, Biochemistry, Chemical synthesis, Analytical Chemistry, Sulfone, chemistry.chemical_compound, chemistry, Deuterium, Drug Discovery, Organic chemistry, Radiology, Nuclear Medicine and imaging, Tritium, Spectroscopy, Lactone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0e179df91aa49e3892230c536f56e640
https://doi.org/10.1002/jlcr.880

المؤلفون: Carl Berthelette, John Scheigetz

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 47:891-894

مصطلحات موضوعية: Diketone, chemistry.chemical_classification, Ketone, Bicyclic molecule, Aryl, Organic Chemistry, Biochemistry, Chemical synthesis, Analytical Chemistry, chemistry.chemical_compound, Deuterium, chemistry, Drug Discovery, Organic chemistry, Radiology, Nuclear Medicine and imaging, Tritium, Spectroscopy, Methyl group

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1433c861823721fc3c22485efcddedc5
https://doi.org/10.1002/jlcr.879

المؤلفون: Michael J. Boyd, Nicolas Lachance, Claudio Sturino, John Scheigetz, Robert Zamboni, Carl Berthelette, Bruno Roy

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 47:107-113

مصطلحات موضوعية: Chemistry, Aryl, Organic Chemistry, Diastereomer, Biochemistry, Chemical synthesis, Analytical Chemistry, chemistry.chemical_compound, Thioether, Bromide, Drug Discovery, Organic chemistry, Radiology, Nuclear Medicine and imaging, Epimer, Pyridinium, Tribromide, Spectroscopy, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::615debe26318fd9a48eee0af0746d32d
https://doi.org/10.1002/jlcr.803

المؤلفون: Bruno Roy, Qingping Wang, Michael J. Gresser, John Scheigetz, Chidambaram Ramachandran

المصدر: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1601:19-28

مصطلحات موضوعية: Phosphatase, Organophosphonates, Biophysics, Protein tyrosine phosphatase, Spodoptera, Transfection, Biochemistry, Cell Line, Substrate Specificity, Analytical Chemistry, Jurkat Cells, chemistry.chemical_compound, Antigens, CD, Animals, Humans, Nucleotide, Tyrosine, Fluorescein, Molecular Biology, chemistry.chemical_classification, Photolysis, Chemistry, Substrate (chemistry), Inositol trisphosphate, Fluoresceins, Recombinant Proteins, Kinetics, Leukocyte Common Antigens, Alkaline phosphatase, Protein Tyrosine Phosphatases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef7bb884a20471cac1963164c0f73ad
https://doi.org/10.1016/s1570-9639(02)00412-0

المؤلفون: Pascal Dube, Michel Belley, Sarah J. Dolman, John Scheigetz

المصدر: Synlett. 2001:0222-0225

مصطلحات موضوعية: Indole test, chemistry.chemical_compound, Trifluoromethyl, chemistry, Organic Chemistry, Carboxylate, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9da2a1b27b6a68b4a431c24e1d6109c5
https://doi.org/10.1055/s-2001-10784

المؤلفون: Bruno Roy, John Scheigetz

المصدر: Synthetic Communications. 30:1437-1445

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Organic Chemistry, Fluorescein, Photochemistry, Fluorescence, Intracellular, Adduct

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1d3e3c0794bba96e584f526ace34cf48
https://doi.org/10.1080/00397910008087172

المؤلفون: Sylvie Desmarais, Chidambaram Ramachandran, Qingping Wang, Robert Zamboni, John Scheigetz, Zheng Huang, Arvind Gorvindarajan, Hoa D. Ly

المصدر: SLAS Discovery. 4:327-334

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Chromogenic, Phosphatase, Substrate (chemistry), Peptide, Protein tyrosine phosphatase, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Hydrolysis, 030104 developmental biology, chemistry, Molecular Medicine, Fluorescein, Tyrosine, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa908a950e0c1790029bafb43f9460a0
https://doi.org/10.1177/108705719900400608

المؤلفون: Qingping Wang, Chidambaram Ramachandran, Michael J. Gilbert, Jamie Snider, John Scheigetz

المصدر: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1431:14-23

مصطلحات موضوعية: Organophosphonates, Biophysics, Substrate (chemistry), Protein tyrosine phosphatase, Fluoresceins, Phosphate, Cleavage (embryo), Biochemistry, Fluorescence, Substrate Specificity, Dephosphorylation, Kinetics, chemistry.chemical_compound, chemistry, Structural Biology, Leukocyte Common Antigens, Spectrophotometry, Ultraviolet, Enzyme kinetics, Protein Tyrosine Phosphatases, Fluorescein, Molecular Biology, Fluorescent Dyes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e84409235335347b54e45d465385d1
https://doi.org/10.1016/s0167-4838(99)00042-4

المؤلفون: Robert Zamboni, Michael J. Gilbert, John Scheigetz

المصدر: Organic Preparations and Procedures International. 29:561-568

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, education, Organic Chemistry, Fluorescein, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::20da031e768b174789f2c30e7451f369
https://doi.org/10.1080/00304949709355232

المؤلفون: Robert Zamboni, Michael A. Bernstein, John Scheigetz, Bruno Roy

المصدر: Organic Preparations and Procedures International. 27:637-644

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Organic Chemistry, N-Acetylneuraminic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::59a43b3c1436e001f20752981fbc474f
https://doi.org/10.1080/00304949509458521

المؤلفون: Robert Zamboni, Bruno Roy, John Scheigetz

المصدر: Synthetic Communications. 25:2791-2806

مصطلحات موضوعية: chemistry.chemical_compound, Ethylene, chemistry, Computational chemistry, Organic Chemistry, Displacement (orthopedic surgery), Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::106f9e4c58892edf1bce90a2ee8c3ebd
https://doi.org/10.1080/00397919508011826

المؤلفون: Elise Isabel, Christophe Mellon, Michael J. Boyd, Nathalie Chauret, Denis Deschênes, Sylvie Desmarais, Jean-Pierre Falgueyret, Jacques Yves Gauthier, Karine Khougaz, Cheuk K. Lau, Serge Léger, Dorothy A. Levorse, Chun Sing Li, Frédéric Massé, M. David Percival, Bruno Roy, John Scheigetz, Michel Thérien, Vouy Linh Truong, Gregg Wesolowski, Robert N. Young, Robert Zamboni, W. Cameron Black

المصدر: Bioorganicmedicinal chemistry letters. 21(3)

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Cathepsin K, Pharmaceutical Science, Administration, Oral, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Dogs, Amide, Drug Discovery, Ethylamines, Animals, Protease Inhibitors, Molecular Biology, Cathepsin, biology, Organic Chemistry, Biphenyl Compounds, Active site, Amides, Rats, Biphenyl compound, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Odanacatib

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7ac2065bec9654d54655621ebfc7a4
https://pubmed.ncbi.nlm.nih.gov/21232956

المؤلفون: John Scheigetz, Michael J. Therien, Dwight Macdonald, John H. Hutchinson, Ernest J. McEachern

المصدر: ChemInform. 24

مصطلحات موضوعية: Indole test, chemistry.chemical_compound, Thiopyran, chemistry, Intramolecular force, Yield (chemistry), Electrophile, Substituent, General Medicine, Lewis acids and bases, Ring (chemistry), Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::851154f00748053ade3cdebd612d19ee
https://doi.org/10.1002/chin.199301189

المؤلفون: John Scheigetz, Jeffrey D. Chambers, Claude Dufresne, Haydn W. R. Williams, Cheuk K. Lau, Michael A. Bernstein, Jason Crawford

المصدر: ChemInform. 24

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Thermal decomposition, Intermolecular force, Ethyl vinyl ether, General Medicine, Medicinal chemistry, Quinone methide, Cycloaddition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1886c907720c5c40f70e8fc6e3278778
https://doi.org/10.1002/chin.199308228

المؤلفون: Christine Brideau, Jocelyne Guay, Thomas R. Jones, H. Piechuta, Rejean Fortin, C. S. Mcfarlane, Daniel Delorme, Jean-Pierre Falgueyret, Denis Riendeau, Pierre Hamel, Michael J. Therien, John Scheigetz, Yves Girard, Philip Tagari, John H. Hutchinson, Dwight Macdonald, D. Denis, Chi-Chung Chan

المصدر: ChemInform. 25

مصطلحات موضوعية: Orally active, biology, Stereochemistry, Chemistry, Arachidonate 5-lipoxygenase, biology.protein, General Medicine, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d09012672934e3b2ea463e60566ee9a5
https://doi.org/10.1002/chin.199410177

المؤلفون: Yves Girard, C. S. Mcfarlane, Jillian F. Evans, Denis Riendeau, Donald W. Nicholson, H. Piechuta, Stella Charleson, Stacia Kargman, Dwight Macdonald, Karst Hoogsteen, John Scheigetz, John H. Hutchinson, Thomas R. Jones, Michael J. Therien, Jean-Pierre Falgueyret

المصدر: ChemInform. 27

مصطلحات موضوعية: chemistry.chemical_compound, Leukotriene C4, chemistry, ATP synthase, biology, Biochemistry, Stereochemistry, Arachidonate 5-lipoxygenase, biology.protein, General Medicine, 5-lipoxygenase-activating protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::18432bb338fa7f5b2840a8eb597ab6ab
https://doi.org/10.1002/chin.199610195