المؤلفون: David Harrison, Mark G. Bock, John R. Doedens, Christopher A. Gabel, M. Katharine Holloway, Arwel Lewis, Jane Scanlon, Andrew Sharpe, Iain D. Simpson, Pamela Smolak, Grant Wishart, Alan P. Watt

المصدر: ACS Medicinal Chemistry Letters. 13:1321-1328

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67241e433174d9710ad5069778aac5f6
https://doi.org/10.1021/acsmedchemlett.2c00242

المؤلفون: Krzysztof Brzózka, Alan P. Watt, Michal Galezowski, Magdalena Mroczkowska, Stefan Chmielewski, Grzegorz Witold Topolnicki, Christopher A. Gabel, David J. Schultz, John R. Doedens, Charles-Henry Fabritius, Oleksandr Levenets, Piotr Kowalczyk, Piotr Urbanski, Katarzyna Palica, Nicolas Boutard, Anna Cierpich, Roderick A. Porter, Marta Bugaj, Jakub Woyciechowski, Marta Sowinska, David G. Harrison

المصدر: Bioorganicmedicinal chemistry letters. 30(23)

مصطلحات موضوعية: Inflammasomes, THP-1 Cells, Clinical Biochemistry, Pharmaceutical Science, Inflammation, Pharmacology, 01 natural sciences, Biochemistry, Heterocyclic Compounds, 4 or More Rings, Proinflammatory cytokine, Carboxylesterase, Mice, Structure-Activity Relationship, Drug Stability, Drug Discovery, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Animals, Humans, Urea, Sulfones, Furans, Molecular Biology, chemistry.chemical_classification, Sulfonamides, Innate immune system, integumentary system, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Rational design, Inflammasome, Esters, Prodrug, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Blood, chemistry, Indenes, Drug Design, Molecular Medicine, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9b9567b37c2ffb77ffeec192329547
https://pubmed.ncbi.nlm.nih.gov/32956781

المؤلفون: John R. Doedens, Thomas H. Giddings, Karla Kirkegaard

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.stanford.edu/group/kirkegaard/pdf/Doedens_JVirology_1997.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.5683; http://www.stanford.edu/group/kirkegaard/pdf/Doedens_JVirology_1997.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.5683
http://www.stanford.edu/group/kirkegaard/pdf/Doedens_JVirology_1997.pdf

المؤلفون: Damien Chaussabel, Wendell D. Jones, Richard J. Martin, Michael Mason, James Posada, Vivian H. Gersuk, Roy Fleischmann, Kay Hill, Maria Dall'Era, Cynthia Aranow, Stanley Cohen, Keith B. Elkon, John R. Doedens, Alan Kivitz, Daniel Burge, Philip J. Mease

المصدر: The Journal of Immunology. 197:2854-2863

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Immunology, Biology, Antigen-Antibody Reactions, Disease activity, 03 medical and health sciences, 0302 clinical medicine, Immune system, immune system diseases, RNA, Small Nuclear, RNA, Small Cytoplasmic, Gene expression, Humans, Lupus Erythematosus, Systemic, Immunology and Allergy, skin and connective tissue diseases, Gene, Autoantibodies, 030203 arthritis & rheumatology, Autoantibody, RNA, Middle Aged, Cross-Sectional Studies, 030104 developmental biology, Gene Expression Regulation, Case-Control Studies, Female, Interferons, Large group, Anti-SSA/Ro autoantibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0098e7ffcba710e274a9b48d78a3b7
https://doi.org/10.4049/jimmunol.1601142

المؤلفون: John R. Doedens, Beverly J Castner, Guixian Jin, Susan W. Sunnarborg, Roy A. Black, R. Cowling, Jennifer L. Slack, Richard S. Johnson, Keith Charrier, Ray Paxton, Duke Virca, David C. Lee, Lin Guo, Alison Wallace, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman

المصدر: Biochemical Society Symposia. 70:39-52

مصطلحات موضوعية: chemistry.chemical_classification, Metalloproteinase, TGF alpha, Alanine, biology, Metalloendopeptidases, Valine, ADAM17 Protein, Biochemistry, ADAM Proteins, Substrate Specificity, Enzyme, chemistry, Enzyme Induction, biology.protein, Disintegrin, Tumor necrosis factor alpha, Enzyme inducer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9727d6426c1d576731fc2cee98f33d8
https://doi.org/10.1042/bss0700039

المؤلفون: John R. Doedens, Ana Cumano, Neetu Gupta, Christel Brou, Roy A. Black, Christine Bessia, Alain Israël, Frédérique Logeat, Pascal Roux, Odile LeBail

المصدر: Molecular Cell. 5:207-216

مصطلحات موضوعية: Serrate-Jagged Proteins, Biochemistry, Notch proteins, Disintegrin, biology.protein, Notch signaling pathway, ADAM17 Protein, Cell Biology, Signal transduction, Biology, Cleavage (embryo), Molecular Biology, ADAM Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0a987d76757f0be96cdedf413511d5
https://doi.org/10.1016/s1097-2765(00)80417-7

المؤلفون: Roy A. Black, Matthew P. Stokes, Jeffrey C. Silva, Kimberly A. Lee, Paul S. Andrews, Tomas Mustelin, Lisa P. Hammerle, John R. Doedens

المصدر: The Journal of biological chemistry. 286(48)

مصطلحات موضوعية: Proteomics, Proteome, Genomics and Proteomics, Immunoprecipitation, Ubiquitin-Protein Ligases, Quantitative proteomics, Ubiquitin-conjugating enzyme, Biochemistry, Arthritis, Rheumatoid, Ubiquitin, Humans, Phosphorylation, Molecular Biology, health care economics and organizations, biology, Ubiquitination, Cell Biology, Protein ubiquitination, Ubiquitin ligase, biology.protein, Protein Processing, Post-Translational, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cb08a223e2e325d2d09239d5d2b154
https://pubmed.ncbi.nlm.nih.gov/21987572

المؤلفون: Rajeev M Mahimkar, John R. Doedens, Roy A. Black

المصدر: Biochemical and biophysical research communications. 308(2)

مصطلحات موضوعية: Cytoplasm, Cell, Biophysics, ADAM17 Protein, Biochemistry, Cell Line, Substrate Specificity, Mice, Transduction, Genetic, Extracellular, medicine, Disintegrin, Animals, Amino Acid Sequence, Molecular Biology, Metalloproteinase, Binding Sites, biology, Cell Membrane, Metalloendopeptidases, Cell Biology, ADAM Proteins, Molecular biology, Protein Structure, Tertiary, medicine.anatomical_structure, Cell culture, biology.protein, Tetradecanoylphorbol Acetate, Tumor necrosis factor alpha, Oligopeptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbaf67f35523541aee4b57ec7be7fa7
https://pubmed.ncbi.nlm.nih.gov/12901873

المؤلفون: John R. Doedens, Roy A. Black

المصدر: The Journal of biological chemistry. 275(19)

مصطلحات موضوعية: Lipopolysaccharides, Molecular Sequence Data, Down-Regulation, Biology, ADAM17 Protein, Endocytosis, Biochemistry, Monocytes, Cell Line, Feedback, chemistry.chemical_compound, Extracellular, Humans, Metalloprotease inhibitor, Amino Acid Sequence, Receptor, Molecular Biology, Cell adhesion molecule, Cell Membrane, Metalloendopeptidases, Cell Biology, Sheddase, Molecular biology, ADAM Proteins, chemistry, Microscopy, Fluorescence, Phorbol, Tetradecanoylphorbol Acetate, Tumor necrosis factor alpha

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc33907b144a2185216d14dd023bdfc7
https://pubmed.ncbi.nlm.nih.gov/10799546

المؤلفون: John R. Doedens, Karla Kirkegaard

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.stanford.edu/group/kirkegaard/pdf/Doedens_EMBO_1995.pdf.

مصطلحات موضوعية: Introduction

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.377.629; http://www.stanford.edu/group/kirkegaard/pdf/Doedens_EMBO_1995.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.377.629
http://www.stanford.edu/group/kirkegaard/pdf/Doedens_EMBO_1995.pdf